Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Rosenfeld, Nitzan"'
Autor:
Weaver, Jamie MJ, Ross-Innes, Caryn S, Shannon, Nicholas, Lynch, Andy G, Forshew, Tim, Barbera, Mariagnese, Murtaza, Muhammed, Ong, Chin-Ann J, Lao-Sirieix, Pierre, Dunning, Mark J, Smith, Laura, Smith, Mike L, Anderson, Charlotte L, Carvalho, Benilton, O'Donovan, Maria, Underwood, Timothy J, May, Andrew P, Grehan, Nicola, Hardwick, Richard, Davies, Jim, Oloumi, Arusha, Aparicio, Sam, Caldas, Carlos, Eldridge, Matthew D, Edwards, Paul AW, Rosenfeld, Nitzan, Tavaré, Simon, Fitzgerald, Rebecca C, OCCAMS Consortium
Publikováno v:
Nature genetics
Cancer genome sequencing studies have identified numerous driver genes, but the relative timing of mutations in carcinogenesis remains unclear. The gradual progression from premalignant Barrett's esophagus to esophageal adenocarcinoma (EAC) provides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e3f5463bad34aca63cca5b88b4991a
Autor:
Mouliere, Florent, Mair, Richard, Chandrananda, Dineika, Marass, Francesco, Smith, Christopher G, Su, Jing, Morris, James, Watts, Colin, Brindle, Kevin M, Rosenfeld, Nitzan
Publikováno v:
EMBO Molecular Medicine, Vol 10, Iss 12, Pp n/a-n/a (2018)
Mouliere, F, Mair, R, Chandrananda, D, Marass, F, Smith, C G, Su, J, Morris, J, Watts, C, Brindle, K M & Rosenfeld, N 2018, ' Detection of cell-free DNA fragmentation and copy number alterations in cerebrospinal fluid from glioma patients ', Embo Molecular Medicine, vol. 10, no. 12, e9323 . https://doi.org/10.15252/emmm.201809323
Embo Molecular Medicine, 10(12):e9323. Wiley-Blackwell
EMBO Molecular Medicine, 10 (12)
EMBO Molecular Medicine
Mouliere, F, Mair, R, Chandrananda, D, Marass, F, Smith, C G, Su, J, Morris, J, Watts, C, Brindle, K M & Rosenfeld, N 2018, ' Detection of cell-free DNA fragmentation and copy number alterations in cerebrospinal fluid from glioma patients ', Embo Molecular Medicine, vol. 10, no. 12, e9323 . https://doi.org/10.15252/emmm.201809323
Embo Molecular Medicine, 10(12):e9323. Wiley-Blackwell
EMBO Molecular Medicine, 10 (12)
EMBO Molecular Medicine
Glioma is difficult to detect or characterize using current liquid biopsy approaches. Detection of cell‐free tumor DNA (cftDNA) in cerebrospinal fluid (CSF) has been proposed as an alternative to detection in plasma. We used shallow whole‐genome
Autor:
Plagnol, Vincent, Woodhouse, Samuel, Howarth, Karen, Lensing, Stefanie, Smith, Matt, Epstein, Michael, Madi, Mikidache, Smalley, Sarah, Leroy, Catherine, Hinton, Jonathan, de Kievit, Frank, Musgrave-Brown, Esther, Herd, Colin, Baker-Neblett, Katherine, Brennan, Will, Dimitrov, Peter, Campbell, Nathan, Morris, Clive, Rosenfeld, Nitzan, Clark, James
Publikováno v:
PLoS ONE; 3/15/2018, Vol. 13 Issue 3, p1-18, 18p
Autor:
Parkinson, Christine A., Gale, Davina, Piskorz, Anna M., Biggs, Heather, Hodgkin, Charlotte, Addley, Helen, Freeman, Sue, Moyle, Penelope, Sala, Evis, Sayal, Karen, Hosking, Karen, Gounaris, Ioannis, Jimenez-Linan, Mercedes, Earl, Helena M., Qian, Wendi, Rosenfeld, Nitzan, Brenton, James D.
Publikováno v:
PLoS Medicine; 12/20/2016, Vol. 13 Issue 12, p1-25, 25p
Autor:
Irena Hudecova, Christopher G. Smith, Robert Hänsel-Hertsch, Chandra S. Chilamakuri, James A. Morris, Aadhitthya Vijayaraghavan, Katrin Heider, Dineika Chandrananda, Wendy N. Cooper, Davina Gale, Javier Garcia-Corbacho, Simon Pacey, Richard D. Baird, Nitzan Rosenfeld, Florent Mouliere
Publikováno v:
Genome Research, 32(2), 215-227. Cold Spring Harbor Laboratory Press
Hudecova, I, Smith, C G, Hänsel-Hertsch, R, Chilamakuri, C S, Morris, J A, Vijayaraghavan, A, Heider, K, Chandrananda, D, Cooper, W N, Gale, D, Garcia-Corbacho, J, Pacey, S, Baird, R D, Rosenfeld, N & Mouliere, F 2022, ' Characteristics, origin, and potential for cancer diagnostics of ultrashort plasma cell-free DNA ', Genome Research, vol. 32, no. 2, pp. 215-227 . https://doi.org/10.1101/gr.275691.121
Hudecova, I, Smith, C G, Hänsel-Hertsch, R, Chilamakuri, C S, Morris, J A, Vijayaraghavan, A, Heider, K, Chandrananda, D, Cooper, W N, Gale, D, Garcia-Corbacho, J, Pacey, S, Baird, R D, Rosenfeld, N & Mouliere, F 2022, ' Characteristics, origin, and potential for cancer diagnostics of ultrashort plasma cell-free DNA ', Genome Research, vol. 32, no. 2, pp. 215-227 . https://doi.org/10.1101/gr.275691.121
Current evidence suggests that plasma cell-free DNA (cfDNA) is fragmented around a mode of 166 bp. Data supporting this view has been mainly acquired through the analysis of double-stranded cfDNA. The characteristics and diagnostic potential of singl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e2e5803e233f3957736b5a114e9e394
https://research.vumc.nl/en/publications/0dcd8aac-b1e7-4e97-8b60-e5c4207bef0c
https://research.vumc.nl/en/publications/0dcd8aac-b1e7-4e97-8b60-e5c4207bef0c
Autor:
Nitzan Rosenfeld, Jonathan C. M. Wan, Katrin Heider, Richard Mair, Marta Grzelak, Dominique-Laurent Couturier, Matthew D. Eldridge, Jing Su, Ymke van der Pol, Dineika Chandrananda, James Morris, Kevin M. Brindle, Colin Watts, Hui Zhao, Florent Mouliere, Irena Hudecova, Mareike Thompson, James Hadfield, Christopher Smith, Wendy N. Cooper, Davina Gale
Publikováno v:
EMBO Molecular Medicine
EMBO Molecular Medicine, Vol 13, Iss 8, Pp n/a-n/a (2021)
Embo Molecular Medicine, 13(8):e12881. Wiley-Blackwell
Mouliere, F, Smith, C G, Heider, K, Su, J, van der Pol, Y, Thompson, M, Morris, J, Wan, J C M, Chandrananda, D, Hadfield, J, Grzelak, M, Hudecova, I, Couturier, D-L, Cooper, W, Zhao, H, Gale, D, Eldridge, M, Watts, C, Brindle, K, Rosenfeld, N & Mair, R 2021, ' Fragmentation patterns and personalized sequencing of cell-free DNA in urine and plasma of glioma patients ', Embo Molecular Medicine, vol. 13, no. 8, e12881 . https://doi.org/10.15252/emmm.202012881, https://doi.org/10.15252/emmm.202012881
EMBO Molecular Medicine, Vol 13, Iss 8, Pp n/a-n/a (2021)
Embo Molecular Medicine, 13(8):e12881. Wiley-Blackwell
Mouliere, F, Smith, C G, Heider, K, Su, J, van der Pol, Y, Thompson, M, Morris, J, Wan, J C M, Chandrananda, D, Hadfield, J, Grzelak, M, Hudecova, I, Couturier, D-L, Cooper, W, Zhao, H, Gale, D, Eldridge, M, Watts, C, Brindle, K, Rosenfeld, N & Mair, R 2021, ' Fragmentation patterns and personalized sequencing of cell-free DNA in urine and plasma of glioma patients ', Embo Molecular Medicine, vol. 13, no. 8, e12881 . https://doi.org/10.15252/emmm.202012881, https://doi.org/10.15252/emmm.202012881
Glioma‐derived cell‐free DNA (cfDNA) is challenging to detect using liquid biopsy because quantities in body fluids are low. We determined the glioma‐derived DNA fraction in cerebrospinal fluid (CSF), plasma, and urine samples from patients usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::579cfd4c20a7898809ae22e22883a395
https://www.repository.cam.ac.uk/handle/1810/325810
https://www.repository.cam.ac.uk/handle/1810/325810
Autor:
Christopher Smith, Katrin Heider, Tevita Aho, Maximilian Seles, Grant D. Stewart, Evis Sala, Johanna Field-Rayner, Irena Hudecova, Charles E. Massie, Anja L. Riediger, Tobias Klatte, Jonathan C. M. Wan, Ellen Heitzer, Florent Mouliere, Wendy N. Cooper, Antony C. P. Riddick, Matthew D. Eldridge, Dineika Chandrananda, James Morris, Tina Moser, Martin Pichler, Davina Gale, Nitzan Rosenfeld, Gabriel Wcislo, Anne Y. Warren, Samantha Perakis, Sarah J. Welsh, Tim Eisen, James N. Armitage, Stephan Ursprung, Thomas J. Mitchell, Andrea Ruiz-Valdepeñas, Athena Matakidou
Publikováno v:
Genome Medicine, Vol 12, Iss 1, Pp 1-17 (2020)
Genome Medicine, 12(1):23. BioMed Central
Smith, C G, Moser, T, Mouliere, F, Field-Rayner, J, Eldridge, M, Riediger, A L, Chandrananda, D, Heider, K, Wan, J C M, Warren, A Y, Morris, J, Hudecova, I, Cooper, W N, Mitchell, T J, Gale, D, Ruiz-Valdepenas, A, Klatte, T, Ursprung, S, Sala, E, Riddick, A C P, Aho, T F, Armitage, J N, Perakis, S, Pichler, M, Seles, M, Wcislo, G, Welsh, S J, Matakidou, A, Eisen, T, Massie, C E, Rosenfeld, N, Heitzer, E & Stewart, G D 2020, ' Comprehensive characterization of cell-free tumor DNA in plasma and urine of patients with renal tumors ', Genome Medicine, vol. 12, no. 1, 23, pp. 23 . https://doi.org/10.1186/s13073-020-00723-8
Genome Medicine
Genome Medicine, 12(1):23. BioMed Central
Smith, C G, Moser, T, Mouliere, F, Field-Rayner, J, Eldridge, M, Riediger, A L, Chandrananda, D, Heider, K, Wan, J C M, Warren, A Y, Morris, J, Hudecova, I, Cooper, W N, Mitchell, T J, Gale, D, Ruiz-Valdepenas, A, Klatte, T, Ursprung, S, Sala, E, Riddick, A C P, Aho, T F, Armitage, J N, Perakis, S, Pichler, M, Seles, M, Wcislo, G, Welsh, S J, Matakidou, A, Eisen, T, Massie, C E, Rosenfeld, N, Heitzer, E & Stewart, G D 2020, ' Comprehensive characterization of cell-free tumor DNA in plasma and urine of patients with renal tumors ', Genome Medicine, vol. 12, no. 1, 23, pp. 23 . https://doi.org/10.1186/s13073-020-00723-8
Genome Medicine
BackgroundCell-free tumor-derived DNA (ctDNA) allows non-invasive monitoring of cancers, but its utility in renal cell cancer (RCC) has not been established.MethodsHere, a combination of untargeted and targeted sequencing methods, applied to two inde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cbab7bf4108a7426b98121afa51b566
https://www.repository.cam.ac.uk/handle/1810/303983
https://www.repository.cam.ac.uk/handle/1810/303983
Autor:
Charles E. Massie, Nitzan Rosenfeld, James Morris, Francesco Marass, Suzanne Murphy, Andreas Mock
Publikováno v:
BMC Medical Genomics, Vol 10, Iss 1, Pp 1-12 (2017)
BMC Medical Genomics
BMC Medical Genomics
Background An increasing number of precision oncology programmes are being launched world-wide. To support this development, we present the Cancer Variant Explorer (CVE), an R package with an interactive Shiny web browser interface. Results Leveragin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e08f7bc8affac98371c5b5b308b780
https://www.repository.cam.ac.uk/handle/1810/264441
https://www.repository.cam.ac.uk/handle/1810/264441