Zobrazeno 1 - 10
of 1 668
pro vyhledávání: '"Gregory, J."'
Autor:
Erica L. Lyons, Daniel Watson, Mohammad S. Alodadi, Sharie J. Haugabook, Gregory J. Tawa, Fady Hannah-Shmouni, Forbes D. Porter, Jack R. Collins, Elizabeth A. Ottinger, Uma S. Mudunuri
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-18 (2023)
Abstract Background Approximately 4–8% of the world suffers from a rare disease. Rare diseases are often difficult to diagnose, and many do not have approved therapies. Genetic sequencing has the potential to shorten the current diagnostic process,
Externí odkaz:
https://doaj.org/article/e690a548a1d4449da411eb08d584528a
Akademický článek
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Autor:
Zeineb Bakey, Oscar A Cabrera, Julia Hoefele, Dinu Antony, Kaman Wu, Michael W Stuck, Dimitra Micha, Thibaut Eguether, Abigail O Smith, Nicole N van der Wel, Matias Wagner, Lara Strittmatter, Philip L Beales, Julie A Jonassen, Isabelle Thiffault, Maxime Cadieux-Dion, Laura Boyes, Saba Sharif, Beyhan Tüysüz, Desiree Dunstheimer, Hans W M Niessen, William Devine, Cecilia W Lo, Hannah M Mitchison, Miriam Schmidts, Gregory J Pazour
Publikováno v:
PLoS Genetics, Vol 19, Iss 6, p e1010796 (2023)
Motile and non-motile cilia play critical roles in mammalian development and health. These organelles are composed of a 1000 or more unique proteins, but their assembly depends entirely on proteins synthesized in the cell body and transported into th
Externí odkaz:
https://doaj.org/article/e3c33751139d4a74a9903b2f1e069797
Autor:
Anthony Z. Wang, Jay A. Bowman-Kirigin, Rupen Desai, Liang-I Kang, Pujan R. Patel, Bhuvic Patel, Saad M. Khan, Diane Bender, M. Caleb Marlin, Jingxian Liu, Joshua W. Osbun, Eric C. Leuthardt, Michael R. Chicoine, Ralph G. Dacey, Gregory J. Zipfel, Albert H. Kim, David G. DeNardo, Allegra A. Petti, Gavin P. Dunn
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-25 (2022)
Abstract Background Recent investigations of the meninges have highlighted the importance of the dura layer in central nervous system immune surveillance beyond a purely structural role. However, our understanding of the meninges largely stems from t
Externí odkaz:
https://doaj.org/article/c17233161de54fbe91f8411660beec7a
Autor:
Sarah C. Pearce, Gregory J. Weber
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/53e61e80c874436294985e541140b93b
Publikováno v:
Genes, Vol 14, Iss 5, p 1061 (2023)
By targeting mRNA transcripts, non-coding small RNAs (sRNAs) regulate the expression of genes governing a wide range of bacterial functions. In the social myxobacterium Myxococcus xanthus, the sRNA Pxr serves as a gatekeeper of the regulatory pathway
Externí odkaz:
https://doaj.org/article/daaee9578aa84ea9b27b2cab75ff5828
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-31 (2021)
Abstract Haplotype phase represents the collective genetic variation between homologous chromosomes and is an essential feature of non-haploid genomes. Here we describe a computational strategy to reliably determine complete whole-chromosome haplotyp
Externí odkaz:
https://doaj.org/article/0bb7695dfc864bdfb41f9ce3ac504c23
Autor:
Benjamin E. Decato, Jianghan Qu, Xiaojing Ji, Elvin Wagenblast, Simon R. V. Knott, Gregory J. Hannon, Andrew D. Smith
Publikováno v:
Epigenetics & Chromatin, Vol 13, Iss 1, Pp 1-14 (2020)
Abstract Background Partially methylated domains (PMDs) are a hallmark of epigenomes in reproducible and specific biological contexts, including cancer cells, the placenta, and cultured cell lines. Existing methods for deciding whether PMDs exist in
Externí odkaz:
https://doaj.org/article/6f0120d5e1dd4e71bfe521b44c8e299b
Publikováno v:
PLoS Genetics, Vol 17, Iss 12, p e1009711 (2021)
Polycystic kidney disease is an inherited degenerative disease in which the uriniferous tubules are replaced by expanding fluid-filled cysts that ultimately destroy organ function. Autosomal dominant polycystic kidney disease (ADPKD) is the most comm
Externí odkaz:
https://doaj.org/article/26217d00b81a43db9143c50e1381457f
Autor:
Ying V. Liu, Clayton P. Santiago, Akin Sogunro, Gregory J. Konar, Ming-wen Hu, Minda M. McNally, Yu-chen Lu, Miguel Flores-Bellver, Silvia Aparicio-Domingo, Kang V. Li, Zhuo-lin Li, Dzhalal Agakishiev, Sarah E. Hadyniak, Katarzyna A. Hussey, Tyler J. Creamer, Linda D. Orzolek, Derek Teng, M. Valeria Canto-Soler, Jiang Qian, Zheng Jiang, Robert J. Johnston, Seth Blackshaw, Mandeep S. Singh
Publikováno v:
Stem Cell Reports. 18:1138-1154