Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Balázs Győrffy"'
Autor:
Stefan Prekovic, Theofilos Chalkiadakis, Merel Roest, Daniel Roden, Catrin Lutz, Karianne Schuurman, Mark Opdam, Liesbeth Hoekman, Nina Abbott, Tanja Tesselaar, Maliha Wajahat, Amy R Dwyer, Isabel Mayayo‐Peralta, Gabriela Gomez, Maarten Altelaar, Roderick Beijersbergen, Balázs Győrffy, Leonie Young, Sabine Linn, Jos Jonkers, Wayne Tilley, Theresa Hickey, Damir Vareslija, Alexander Swarbrick, Wilbert Zwart
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 12, Pp n/a-n/a (2023)
Abstract Glucocorticoid receptor (GR) is a transcription factor that plays a crucial role in cancer biology. In this study, we utilized an in silico‐designed GR activity signature to demonstrate that GR relates to the proliferative capacity of nume
Externí odkaz:
https://doaj.org/article/7f89e9b972df425581429cdb0b5d1a09
Publikováno v:
BMC Medical Genomics, Vol 10, Iss 1, Pp 1-8 (2017)
Abstract Background Inhibition of the PD-L1/PD-1 immune checkpoint axis represents one of the most promising approaches of immunotherapy for various cancer types. However, immune checkpoint inhibition is successful only in subpopulations of patients
Externí odkaz:
https://doaj.org/article/d34c25e1b6b9400b83beb86ea0eebc2c
Autor:
Crismita Dmello, Aarón Sonabend, Victor A. Arrieta, Daniel Y. Zhang, Deepak Kanojia, Li Chen, Andrew Gould, Jiangshan Zhang, Seong Jae Kang, Jan Winter, Craig Horbinski, Christina Amidei, Balázs Győrffy, Alex Cordero, Catalina Lee Chang, Brandyn Castro, Patrick Hsu, Atique U. Ahmed, Maciej S. Lesniak, Roger Stupp, Adam M. Sonabend
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research, vol 28, iss 14
Clin Cancer Res
Clin Cancer Res
Purpose: Paclitaxel (PTX) is one of the most potent and commonly used chemotherapies for breast and pancreatic cancer. Several ongoing clinical trials are investigating means of enhancing delivery of PTX across the blood–brain barrier for glioblast
Autor:
Balázs Győrffy
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 4101-4109 (2021)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Graphical abstract
Introduction Extensive research is directed to uncover new biomarkers capable to stratify breast cancer patients into clinically relevant cohorts. However, the overall performance ranking of such marker candidates compared to
Introduction Extensive research is directed to uncover new biomarkers capable to stratify breast cancer patients into clinically relevant cohorts. However, the overall performance ranking of such marker candidates compared to
Autor:
Balázs Győrffy, Otília Menyhárt
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 949-960 (2021)
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal
Highlights • Single-level data analysis produced by high-throughput technologies is limited by showing only a narrow window of cellular functions. • Data integration across different platforms, including genomics, epigenomics, transcriptomics, pr
Autor:
Jan Winter, Chidiebere U. Awah, Markella Zannikou, Denise M. Scholtens, Regina T. Martuscello, Edgar Gonzalez-Buendia, Li Chen, Patrick D. Hsu, Silvana Konerman, Atique Ahmed, Roger Stupp, Daniel Zhang, Dou Yu, Irina V. Balyasnikova, Louisa Warnke, Mukesh Bansal, Balázs Győrffy, Cheol Park, Kirsten Bell Burdett, Adam M. Sonabend, Meeki Lad, Aayushi Mahajan, Eric Feldstein
Publikováno v:
Oncogene
Oncogene, vol 39, iss 27
Oncogene, vol 39, iss 27
Topoisomerase II poisons are one of the most common class of chemotherapeutics used in cancer. We and others had shown that a subset of glioblastomas (GBM), the most malignant of all primary brain tumors in adults, are responsive to TOP2 poisons. To
Autor:
Jing Chen, Liqing Li, Cai Huang, Haining Zhu, Vesa P. Hytönen, Olli T. Pentikäinen, Sampo Kukkurainen, Zbigniew Baster, Zenon Rajfur, Balázs Győrffy
Publikováno v:
The FASEB Journal. 34:2227-2237
Cyanidin-3-glucoside (C3G) is a natural pigment, found in many colorful fruits and vegetables. It has many health benefits, including anti-inflammation, cancer prevention, and anti-diabetes. Although C3G is assumed to be an antioxidant, it has been r
Autor:
Andreas Möller, Cheng Liu, Futoshi Kawamata, Balázs Győrffy, Caroline Atkinson, Ming Q. Wei, Vicki L. J. Whitehall, Sunyoung Ham, Adrian P. Wiegmans, Alan L. Munn
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 13, Iss 4, Pp 725-737 (2019)
Molecular Oncology, Vol 13, Iss 4, Pp 725-737 (2019)
Epidermal growth factor receptor (EGFR) supports colorectal cancer progression via oncogenic signaling. Anti-EGFR therapy is being investigated as a clinical option for colorectal cancer, and an observed interaction between EGFR and Prion protein has
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0245824 (2021)
PLoS ONE
PLoS ONE
Scientists from nearly all disciplines face the problem of simultaneously evaluating many hypotheses. Conducting multiple comparisons increases the likelihood that a non-negligible proportion of associations will be false positives, clouding real dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70982aa28a9c4a9d3f904f21bb861076
https://doi.org/10.1101/2021.01.11.426197
https://doi.org/10.1101/2021.01.11.426197
Publikováno v:
International Journal of Antimicrobial Agents
Highlights • A database of 4566 SARS-CoV-2 virus sequences and follow-up data was established • Mutations were mapped to amino acid changes for 3,733 non-silent mutations • Mutations correlated to mild outcome were located in the ORF8, NSP6, OR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2041c4271f1d137e88b6c6990013e03
https://doi.org/10.1101/2020.10.16.20213710
https://doi.org/10.1101/2020.10.16.20213710