Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Akinori Kashimura"'
Autor:
Eri Tabata, Akihiro Itoigawa, Takumi Koinuma, Hiroshi Tayama, Akinori Kashimura, Masayoshi Sakaguchi, Vaclav Matoska, Peter O Bauer, Fumitaka Oyama
Publikováno v:
Molecular Biology and Evolution
Acidic chitinase (Chia) digests the chitin of insects in the omnivorous stomach and the chitinase activity in carnivorous Chia is significantly lower than that of the omnivorous enzyme. However, mechanistic and evolutionary insights into the function
Autor:
Shunsuke Kobayashi, Fumitaka Oyama, Vaclav Matoska, Shotaro Honda, Yasusato Sugahara, Akinori Kashimura, Peter O. Bauer, Minori Kamaya, Masayoshi Sakaguchi, Masahiro Kimura, Satoshi Wakita
Publikováno v:
FEBS Letters. 591:3310-3318
Mouse acidic mammalian chitinase (AMCase) degrades chitin with highest efficiency at pH 2.0 and is active up to pH 8.0. Here, we report that mouse AMCase also exhibits transglycosylation activity under neutral conditions. We incubated natural and art
Autor:
Yuki Kobayashi, Yoshihiro Kino, Akinori Kashimura, Misa Ohno, Kazuaki Okawa, Fumitaka Oyama, Masahiro Kimura, Minori Kamaya, Masayoshi Sakaguchi, Peter O. Bauer, Yasusato Sugahara
Publikováno v:
Molecular Biology and Evolution
Acidic mammalian chitinase (AMCase) is implicated in asthma, allergic inflammation, and food processing. Little is known about genetic and evolutional regulation of chitinolytic activity of AMCase. Here, we relate human AMCase polymorphisms to the mo
Autor:
Akira Sato, Akinori Kashimura, Fumitaka Oyama, Peter O. Bauer, Kazuaki Okawa, Kazutaka Sekine, Daisuke Yamanaka, Kotarou Ishikawa, Yasusato Sugahara, Masayoshi Sakaguchi, Naohito Ohno, Satoshi Yoshikawa, Satoshi Wakita, Masahiro Kimura
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164367 (2016)
PLoS ONE
PLoS ONE
Chitotriosidase (Chit1) is an enzyme associated with various diseases, including Gaucher disease, chronic obstructive pulmonary disease, Alzheimer disease and cystic fibrosis. In this study, we first expressed mouse mature Chit1 fused with V5 and (Hi