Zobrazeno 1 - 10
of 183 608
pro vyhledávání: '"medicine"'
Autor:
Jose H Arteaga, Jorma Hinkula, Edvard C.I Smith, Britta Wahren, Abdalla J. Mohamed, Maria E. Cardona, Kristin Gustafsson, Birger Christensson
Publikováno v:
Molecular Biology Reports. 49:11187-11192
Treatment with RNAi against HIV-1 transcripts efficiently inhibits viral replication but induces selection of escape mutants; therefore, the CCR5 coreceptor was suggested as an additional target. Blocking viral and host transcripts improved the antiv
Publikováno v:
Journal of Clinical Research in Pediatric Endocrinology. 15:97-102
Kenny-Caffey syndrome (KCS) is a rare autosomal recessive/dominant disease characterized by hypoparathyroidism, skeletal dysplasia, dwarfism, and dysmorphism. FAM111A or TBCE gene mutations are responsible for this syndrome. Osteocraniostenosis (OCS)
Autor:
Lei Liu, Jia Wu, Minxin Shi, Fengying Wang, Haimin Lu, Jibing Liu, Weiqin Chen, Guanzhen Yu, Dan Liu, Jing Yang, Qin Luo, Yan Ni, Xing Jin, Xiaoxia Jin, Wen-Lian Chen
Publikováno v:
Genomics, Proteomics & Bioinformatics. 20:670-687
Esophageal squamous cell carcinoma (ESCC) is a major histological subtype of esophageal cancer with a poor prognosis. Although several serum metabolomic investigations have been reported, ESCC tumor-associated metabolic alterations and predictive bio
Autor:
Hanieh Behravan, Ahmad Piroozmand, Azam Ghaziasadi, Khadijeh Jalalvand, Mahdieh Koshki, Fatemeh Tavangar, Angila Ataei-Pirkooh, Farid Yousefi, Masoumeh Bayani, Zohreh Fattahi, Hamed Fakhim, Mojtaba Varshochi, Mohammad Khazeni, Zakiye Mokhames, Fariba Shahraki-Sanavi, Reza Malekzadeh, Maryam Beheshtian, Yousef Yahyapour, Seyed Jalal Kiani, Fariba Keramat, Shokouh Ghafari, Behrooz Ataei, Alireza Abdollahi, Afagh Moattari, Fatemeh Keshavarzi, Mohammad Reza Haghshenas, Alireza AnsariMoghaddam, Maryam Azad, Mohammad Hassan Pouriayevali, Mohsen Moghadami, Azarakhsh Azaran, Zohreh Elahi, Farhang Babamahmoodi, Mohamad Soveyzi, Kimia Kahrizi, Hamid Reza Khorram Khorshid, Vahdat Poortahmasebi, Reza Najafipour, Farzane Zare Ashrafi, Akram Ezani, Farid Azizi Jalilian, Mostafa Salehi-Vaziri, Seyed Mohammad Jazayeri, Seyed Mohammad Hashemi-Shahri, Abdolvahab Moradi, Ali Mojtahedi, Fatemeh Ghodratpour, Marzieh Mohseni, Davod Javanmard, Mahsa Tavakoli, Ali Jafarpour, Hossein Najmabadi, Alijan Tabarraei, Alireza Soleimani, Tahmineh Jalali, Elahe Nasri, Mahmood Yaghoubi, Marzieh Kalhor, Farah Bokharaei-Salim, Iman Rezaeiazhar, Masood Ziaee
Publikováno v:
Archives of Iranian Medicine. 25:508-522
SARS-CoV-2 genome surveillance projects provide a good measure of transmission and monitor the circulating SARS-CoV-2 variants at regional and global scales. Iran is one of the most affected countries still involved with the virus circulating in at l
Autor:
Silvestre I, Sílvia Duarte, Sobral R, Luís Vieira, Alexandra Nunes, João Paulo Gomes, Borges, Maria José Borrego
Publikováno v:
Cellular and Molecular Biology. 68:1-8
Streptococcus agalactiae is a leading cause of neonatal infections and an increasing cause of infections in adults with underlying diseases. One of the first S. agalactiae isolates to be subjected to whole genome sequencing was NEM316, a strain respo
Autor:
Johnathan Abou-Fadel, Muaz Bhalli, Brian Grajeda, Alyssa-Marie D. Cailing-De La O, Akhil Padarti, Alexander D. Le, Jun Zhang, Xiaoting Jiang, Esmeralda Flores
Publikováno v:
Cancer Biomarkers. 34:607-636
Breast cancer is the most commonly diagnosed cancer worldwide and remains the second leading cause of cancer death. While breast cancer mortality has steadily declined over the past decades through medical advances, an alarming disparity in breast ca
Autor:
Amy Hurford, Abdou Moutalab Fofana
Publikováno v:
Journal of Evolutionary Biology. 35:1072-1086
Many parasites induce decreased host movement, known as lethargy, which can impact disease spread and the evolution of virulence. Mathematical models have investigated virulence evolution when parasites cause host death, but disease-induced decreased
Autor:
Yesennia Sánchez-Pérez, Yolanda I. Chirino, Miguel Santibáñez-Andrade, Diddier Prada, Claudia M. García-Cuellar, Octavio Alonso Larraga, Dennis Cerrato-Izaguirre, Javier Camacho, Angélica Hernández-Guerrero
Publikováno v:
Genes & Diseases. 9:928-940
Latin-America (LATAM) is the second region in gastric cancer incidence; gastric adenocarcinoma (GA) represents 95% of all cases. We provide a mutational landscape of GA highlighting a) germline pathogenic variants associated with hereditary GA, b) ge
Autor:
Cliff Heindel, Karlaina J.L. Osmon, Evan Woodley, John G. Keimel, Patrick Thompson, Subha Karumuthil-Melethil, William F. Kaemmerer, Jagdeep S. Walia, Steven J. Gray
Publikováno v:
Current Gene Therapy. 22:262-276
Background: GM2 gangliosidosis is a neurodegenerative, lysosomal storage disease caused by the deficiency of β-hexosaminidase A enzyme (Hex A), an α/β-subunit heterodimer. A novel variant of the human hexosaminidase α-subunit, coded by HEX M, has
Publikováno v:
Current Gene Therapy. 22:185-190
Pre existing immunity to Adeno-Associated Virus (AAV) poses a concern in AAV vector– mediated gene therapy. Localized administration of low doses of carefully chosen AAV serotypes can mitigate the risk of an immune response. This article will illus