Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Gwendolyn Binder-Scholl"'
Autor:
Travis Wood, Dawn A. Maier, Andrea L. Brennan, Gabriela Plesa, Carl H. June, Gary Lee, Julio Cotte, Elena E. Perez, Bruce L. Levine, S. Kaye Spratt, Carmine Carpenito, Richard G. Carroll, Zhaohui Zheng, Philip D. Gregory, Michael C. Holmes, Gwendolyn Binder-Scholl, James L. Riley, Dale Ando, Shuguang Jiang
Publikováno v:
Human Gene Therapy. 24:245-258
Since HIV requires CD4 and a co-receptor, most commonly C-C chemokine receptor 5 (CCR5), for cellular entry, targeting CCR5 expression is an attractive approach for therapy of HIV infection. Treatment of CD4(+) T cells with zinc-finger protein nuclea
Autor:
Elizabeth Veloso, Zhaohui Zheng, Faten Aberra, Adonna Mackley, Jenny Zhan, Julio Cotte, Jean D. Boyer, Wei-Ting Hwang, Andrea L. Brennan, Ronald G. Collman, Troy Brady, Bruce L. Levine, Carl H. June, Tessio Rebello, Pablo Tebas, Luis J. Montaner, Rithun Mukherjee, Gwendolyn Binder-Scholl, David Stein, Michael Kalos, Daniel Schullery, Farida Shaheen, Vladimir Slepushkin, Frederic D. Bushman, Emmanouil Papasavvas, Laurent Humeau
Publikováno v:
Blood. 121(9)
We report the safety and tolerability of 87 infusions of lentiviral vector–modified autologous CD4 T cells (VRX496-T; trade name, Lexgenleucel-T) in 17 HIV patients with well-controlled viremia. Antiviral effects were studied during analytic treatm
Autor:
Naomi E. Aronson, Bruce L. Levine, Troy Brady, James L. Riley, John Scholler, Ronald T. Mitsuyasu, Gabriela Plesa, Steven G. Deeks, Ashley N. Vogel, Wendy B. Bernstein, Gwendolyn Binder-Scholl, Carl H. June, Michael Kalos, Kristen Hege, Frederic D. Bushman, Wei-Ting Hwang
Publikováno v:
Science Translational Medicine. 4
The success of adoptive T cell gene transfer for treatment of cancer and HIV is predicated on generating a response that is both durable and safe. We report long-term results from three clinical trials to evaluate gammaretroviral vector–engineered
Autor:
Carl H. June, Gianpietro Dotti, Steven A. Feldman, Gwendolyn Binder-Scholl, Steven A. Rosenberg, Helen E. Heslop, Cliona M. Rooney, Mark E. Dudley, Richard A. Morgan, Kenneth Cornetta, Sheila A Shurtleff, Adham S. Bear
Adoptive T-cell transfer is recognized as an innovative treatment strategy for various malignant diseases.1,2 To improve the efficacy and sometimes the safety of this approach, T cells can be genetically manipulated to modify their antigen specificit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e67a10253d0fb50aaa14ebaa906cded
https://europepmc.org/articles/PMC3277217/
https://europepmc.org/articles/PMC3277217/