Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Brian O'Connell"'
Publikováno v:
Human Gene Therapy. 12:2215-2223
Adenoviral vectors efficiently deliver exogenous genes to salivary glands. There are two general epithelial cell types, with very different functions, in salivary glands--acinar and ductal. To determine if gene expression can be restricted in vivo to
Publikováno v:
Nature Biotechnology. 18:176-180
A replication-deficient recombinant adenovirus encoding luciferase was constructed using 5' and 3' long terminal repeat (LTR) sequences of the Moloney murine leukemia virus. Gene expression was observed in cultured cells in vitro and in submandibular
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 268:G1074-G1078
The internalization of DNA can be facilitated by adenovirus infection. Using the replication-deficient adenovirus, Ad-dl312, and a plasmid-based firefly luciferase gene as a reporter, we have optimized the uptake and expression of DNA in rat submandi
Autor:
Christine Delporte, Brian O'Connell, Xinjun He, Peter Agre, Anne C. O'Connell, Bruce J. Baum, Henry E. Lancaster
A replication-deficient, recombinant adenovirus encoding human aquaporin-1 (hAQP1), the archetypal water channel, was constructed. This virus, AdhAQP1, directed hAQP1 expression in several epithelial cell lines in vitro . In polarized MDCK cell monol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a004255148b6a4f983dea4f77de2099c
https://europepmc.org/articles/PMC20358/
https://europepmc.org/articles/PMC20358/
Autor:
Thomas J. Walsh, Tao Xu, Frank G. Oppenheim, Ronald G. Crystal, Andrea Mastrangeli, Brian O'Connell, Tin Sein, Bruce J. Baum
Publikováno v:
Human gene therapy. 7(18)
Mucosal candidiasis, the most common opportunistic fungal infection in human immunodeficiency virus (HIV)-infected patients, is an early sign of clinically overt acquired immunodeficiency syndrome (AIDS) and an important cause of morbidity, particula
Autor:
C D Lillibridge, G Miller, Bruce J. Baum, Jane C. Atkinson, Christine Delporte, Brian O'Connell, Hideaki Kagami
Publikováno v:
Scopus-Elsevier
We have examined the safety of a replication-deficient recombinant adenovirus administered at a single, high dose intraductally to rat submandibular glands or systemically via the femoral vein. The virus used directed the synthesis of human aquaporin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a123cca0932593dd3470c2bd968df5d
http://www.scopus.com/inward/record.url?eid=2-s2.0-0031984649&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0031984649&partnerID=MN8TOARS