Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Songchang Chen"'
Publikováno v:
Gene. 819
Substantial evidence now suggests an association between the FMR1 genotype and female fertility. The aim of this study was to determine whether a high normal FMR1 allele (35-54 repeats) affects in vitro fertilization (IVF) outcomes in Chinese women.
Publikováno v:
Frontiers in Genetics; 9/9/2022, Vol. 13, p1-6, 6p
Autor:
Songchang Chen, Weihui Shi, Yeqing Qian, Liya Wang, Junyu Zhang, Shuyuan Li, Yiyao Chen, Chunxin Chang, Hongjun Fei, Lanlan Zhang, Hefeng Huang, Chenming Xu
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Frontiers in Genetics
Frontiers in Genetics
Background X-linked lymphoproliferative disease (XLP) is a rare primary immunodeficiency disorder. We performed experiments based on two strategies of preimplantation genetic testing (PGT) for a family with XLP caused by a mutation in SH2D1A (c.191G
Publikováno v:
Frontiers in Genetics, Vol 10 (2020)
Frontiers in Genetics
Frontiers in Genetics
Alagille syndrome (ALGS), as known as congenital arteriohepatic dysplasia, is a rare autosomal dominant multi-systemic disorder. Mutations in JAG1 or more rarely NOTCH2 have been reported as the cause of ALGS. In this study, a 5-year old girl with ty
Autor:
Pingyuan Xie, Jun-Yu Zhang, Xuyang Yin, Yuting Hu, Hui Jiang, Xinming Liang, Ge Lin, Huijuan Yan, Hongjun Fei, Songchang Chen, Sijia Zhang, Fang Chen, Jun Xia, Yiyao Chen, Lanlan Zhang, Chenming Xu, Ping Liu
Publikováno v:
Human reproduction (Oxford, England). 36(1)
STUDY QUESTION Can whole genome sequencing (WGS) offer a relatively cost-effective approach for embryonic genome-wide haplotyping and preimplantation genetic testing (PGT) for monogenic disorders (PGT-M), aneuploidy (PGT-A) and structural rearrangeme
Autor:
Jun-Yu Zhang, Chenming Xu, Songchang Chen, Yu-Qian Xiang, Yinghua Shen, He-Feng Huang, Chunxin Chang, Yiyao Chen, Lanlan Zhang, Shuyuan Li
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172173 (2017)
PLoS ONE
PLoS ONE
X-linked lymphoproliferative disease type 1 (XLP1) is a rare primary immunodeficiency characterized by a clinical triad consisting of severe EBV-induced hemophagocytic lymphohistiocytosis, B-cell lymphoma, and dysgammaglobulinemia. Mutations in SH2D1
Autor:
Li Jin, Songchang Chen, Chenming Xu, Guo-Lian Ding, Jun-Yu Zhang, Xiao-Nan Yang, Changlin Mei, Dong-Mei Sun, Xiao-Li Xu, Bei Liu, He-Feng Huang
Publikováno v:
Scientific Reports
Here, we evaluate the applicability of a new method that combines targeted next-generation sequencing (NGS) with targeted haplotyping in identifying PKD2 gene mutations in human preimplantation embryos in vitro. To achieve this goal, a proband family