Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Wiggs, Janey L."'
Autor:
Gharahkhani, Puya, Jorgenson, Eric, Hysi, Pirro, Khawaja, Anthony P, Pendergrass, Sarah, Han, Xikun, Ong, Jue Sheng, Hewitt, Alex W, Segrè, Ayellet V, Rouhana, John M, Hamel, Andrew R, Igo, Robert P, Choquet, Helene, Qassim, Ayub, Josyula, Navya S, Cooke Bailey, Jessica N, Bonnemaijer, Pieter WM, Iglesias, Adriana, Siggs, Owen M, Young, Terri L, Vitart, Veronique, Thiadens, Alberta AHJ, Karjalainen, Juha, Uebe, Steffen, Melles, Ronald B, Nair, K Saidas, Luben, Robert, Simcoe, Mark, Amersinghe, Nishani, Cree, Angela J, Hohn, Rene, Poplawski, Alicia, Chen, Li Jia, Rong, Shi-Song, Aung, Tin, Vithana, Eranga Nishanthie, NEIGHBORHOOD consortium, ANZRAG consortium, Biobank Japan project, FinnGen study, UK Biobank Eye and Vision Consortium, GIGA study group, 23 and Me Research Team, Tamiya, Gen, Shiga, Yukihiro, Yamamoto, Masayuki, Nakazawa, Toru, Currant, Hannah, Birney, Ewan, Wang, Xin, Auton, Adam, Lupton, Michelle K, Martin, Nicholas G, Ashaye, Adeyinka, Olawoye, Olusola, Williams, Susan E, Akafo, Stephen, Ramsay, Michele, Hashimoto, Kazuki, Kamatani, Yoichiro, Akiyama, Masato, Momozawa, Yukihide, Foster, Paul J, Khaw, Peng T, Morgan, James E, Strouthidis, Nicholas G, Kraft, Peter, Kang, Jae H, Pang, Chi Pui, Pasutto, Francesca, Mitchell, Paul, Lotery, Andrew J, Palotie, Aarno, van Duijn, Cornelia, Haines, Jonathan L, Hammond, Chris, Pasquale, Louis R, Klaver, Caroline CW, Hauser, Michael, Khor, Chiea Chuen, Mackey, David A, Kubo, Michiaki, Cheng, Ching-Yu, Craig, Jamie E, MacGregor, Stuart, Wiggs, Janey L
Publikováno v:
Nature Communications, 12(1):1258. Nature Publishing Group
NEIGHBORHOOD Consortium, ANZRAG consortium, Biobank Japan project, FinnGen study, UK Biobank Eye and Vision Consortium, GIGA study group & 23 and Me Research Team 2021, ' Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries ', Nature Communications, vol. 12, no. 1, 1258 . https://doi.org/10.1038/s41467-020-20851-4
Nature Communications
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications, 12
Nature Communications, 12, 1
NEIGHBORHOOD Consortium, ANZRAG consortium, Biobank Japan project, FinnGen study, UK Biobank Eye and Vision Consortium, GIGA study group & 23 and Me Research Team 2021, ' Genome-wide meta-analysis identifies 127 open-angle glaucoma loci with consistent effect across ancestries ', Nature Communications, vol. 12, no. 1, 1258 . https://doi.org/10.1038/s41467-020-20851-4
Nature Communications
Nature communications, vol 12, iss 1
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications, 12
Nature Communications, 12, 1
Primary open-angle glaucoma (POAG), is a heritable common cause of blindness world-wide. To identify risk loci, we conduct a large multi-ethnic meta-analysis of genome-wide association studies on a total of 34,179 cases and 349,321 controls, identify
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb7d731b3bc4c940606176a1a6a7f6af
https://pure.eur.nl/en/publications/729a5ab4-4899-4eec-b043-33a2963a1b20
https://pure.eur.nl/en/publications/729a5ab4-4899-4eec-b043-33a2963a1b20
Autor:
Bonnemaijer, Pieter WM, van Leeuwen, Elisabeth M, Iglesias, Adriana I, Gharahkhani, Puya, Vitart, Veronique, Khawaja, Anthony P, Simcoe, Mark, Hoehn, Rene, Cree, Angela J, Igo, Rob P, Burdon, Kathryn P, Craig, Jamie E, Hewitt, Alex W, Jonas, Jost, Khor, Chiea-Cheun, Pasutto, Francesca, Mackey, David A, Mitchell, Paul, Mishra, Aniket, Pang, Calvin, Pasquale, Louis R, Springelkamp, Henriette, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, Viswanathan, Ananth C, Wojciechowski, Robert, Wong, Tien, Young, Terrri L, Zeller, Tanja, Atan, Denize, Aslam, Tariq, Barman, Sarah A, Barrett, Jenny H, Bishop, Paul, Blows, Peter, Bunce, Catey, Carare, Roxana O, Chakravarthy, Usha, Chan, Michelle, Chua, Sharon YL, Crabb, David P, Cumberland, Philippa M, Day, Alexander, Desai, Parul, Dhillon, Bal, Dick, Andrew D, Egan, Cathy, Ennis, Sarah, Foster, Paul, Fruttiger, Marcus, Gallacher, John EJ, Garway, David F, Gibson, Jane, Gore, Dan, Guggenheim, Jeremy A, Hardcastle, Alison, Harding, Simon P, Hogg, Ruth E, Keane, Pearse A, Khaw, Peng T, Lascaratos, Gerassimos, Macgillivray, Tom, Mackie, Sarah, Martin, Keith, McGaughey, Michelle, McGuinness, Bernadette, Mckay, Gareth J, McKibbin, Martin, Mitry, Danny, Moore, Tony, Morgan, James E, Muthy, Zaynah A, O'Sullivan, Eoin, Owen, Chris G, Patel, Praveen, Paterson, Euan, Peto, Tunde, Petzold, Axel, Rahi, Jugnoo S, Rudnikca, Alicja R, Self, Jay, Sivaprasad, Sobha, Steel, David, Stratton, Irene, Strouthidis, Nicholas, Sudlow, Cathie, Thomas, Dhanes, Trucco, Emanuele, Tufail, Adnan, Vernon, Stephen A, Williams, Cathy, Williams, Katie, Woodside, Jayne V, Yates, Max M, Yip, Jennifer, Zheng, Yalin, Allingham, Rand, Budenz, Don, Bailey, Jessica Cooke, Fingert, John, Gaasterland, Douglas, Gaasterland, Teresa, Haines, Jonathan L, Hark, Lisa, Hauser, Michael, Kang, Jae Hee, Kraft, Peter, Lee, Richard, Lichter, Paul, Liu, Yutao, Moroi, Syoko, Pericak, Margaret, Realini, Anthony, Rhee, Doug, Richards, Julia R, Ritch, Robert, Scott, William K, Singh, Kuldev, Sit, Arthur, Vollrath, Douglas, Weinreb, Robert, Wollstein, Gadi, Wilmer, Don Zack, Gerhold-Ay, Aslihan, Nickels, Stefan, Wilson, James F, Hayward, Caroline, Boutin, Thibaud S, Polasek, Ozren, Aung, Tin, Khor, Chiea Chuen, Amin, Najaf, Lotery, Andrew J, Wiggs, Janey L, Cheng, Ching-Yu, Hysi, Pirro G, Hammond, Christopher J, Thiadens, Alberta AHJ, MacGregor, Stuart, Klaver, Caroline CW, van Duijn, Cornelia M, Consortium, Int Glaucoma Genetics, Consortium, Uk Biobank Eye Vision, Consortium, NEIGHBORHOOD
Publikováno v:
Communications Biology, Vol 2, Iss 1, Pp 1-12 (2019)
Communications Biology, 2:Unsp 435. Springer Nature
Communications biology, vol 2, iss 1
COMMUNICATIONS BIOLOGY
Communications Biology, 2, 435
Bonnemaijer, Pieter W M; Leeuwen, Elisabeth M van; Iglesias, Adriana I; Gharahkhani, Puya; Vitart, Veronique; Khawaja, Anthony P; Simcoe, Mark; Höhn, René; Cree, Angela J; Igo, Rob P; Gerhold-Ay, Aslihan; Nickels, Stefan; Wilson, James F; Hayward, Caroline; Boutin, Thibaud S; Polašek, Ozren; Aung, Tin; Khor, Chiea Chuen; Amin, Najaf; Lotery, Andrew J; ... (2019). Multi-trait genome-wide association study identifies new loci associated with optic disc parameters. Communications biology, 2, p. 435. Springer Nature 10.1038/s42003-019-0634-9
International Glaucoma Genetics Consortium, NEIGHBORHOOD consortium & UK Biobank Eye and Vision Consortium 2019, ' Multi-trait genome-wide association study identifies new loci associated with optic disc parameters ', Communications Biology, vol. 2, no. 1, 435 . https://doi.org/10.1038/s42003-019-0634-9
Atan, D & van Duijn, C & et, A 2019, ' Multi-trait genome-wide association study identifies new loci associated with optic disc parameters ', Communications Biology, vol. 2, 435 (2019) . https://doi.org/10.1038/s42003-019-0634-9
Communications Biology
Bonnemaijer, P, van Leeuwen, E M, Iglesias, A I, Gharahkhani, P, Vitart, V, Khawaja, A P, Simcoe, M, Höhn, R, Cree, A J, Igo, R P & Gerhold-Ay, A & Wilson, J & Hayward, C & Boutin, T 2019, ' Multi-trait genome-wide association study identifies new loci associated with optic disc parameters ', Communications biology . https://doi.org/10.1038/s42003-019-0634-9
Communications Biology, 2, pp. 435
Communications Biology, 2:Unsp 435. Springer Nature
Communications biology, vol 2, iss 1
COMMUNICATIONS BIOLOGY
Communications Biology, 2, 435
Bonnemaijer, Pieter W M; Leeuwen, Elisabeth M van; Iglesias, Adriana I; Gharahkhani, Puya; Vitart, Veronique; Khawaja, Anthony P; Simcoe, Mark; Höhn, René; Cree, Angela J; Igo, Rob P; Gerhold-Ay, Aslihan; Nickels, Stefan; Wilson, James F; Hayward, Caroline; Boutin, Thibaud S; Polašek, Ozren; Aung, Tin; Khor, Chiea Chuen; Amin, Najaf; Lotery, Andrew J; ... (2019). Multi-trait genome-wide association study identifies new loci associated with optic disc parameters. Communications biology, 2, p. 435. Springer Nature 10.1038/s42003-019-0634-9
International Glaucoma Genetics Consortium, NEIGHBORHOOD consortium & UK Biobank Eye and Vision Consortium 2019, ' Multi-trait genome-wide association study identifies new loci associated with optic disc parameters ', Communications Biology, vol. 2, no. 1, 435 . https://doi.org/10.1038/s42003-019-0634-9
Atan, D & van Duijn, C & et, A 2019, ' Multi-trait genome-wide association study identifies new loci associated with optic disc parameters ', Communications Biology, vol. 2, 435 (2019) . https://doi.org/10.1038/s42003-019-0634-9
Communications Biology
Bonnemaijer, P, van Leeuwen, E M, Iglesias, A I, Gharahkhani, P, Vitart, V, Khawaja, A P, Simcoe, M, Höhn, R, Cree, A J, Igo, R P & Gerhold-Ay, A & Wilson, J & Hayward, C & Boutin, T 2019, ' Multi-trait genome-wide association study identifies new loci associated with optic disc parameters ', Communications biology . https://doi.org/10.1038/s42003-019-0634-9
Communications Biology, 2, pp. 435
A new avenue of mining published genome-wide association studies includes the joint analysis of related traits. The power of this approach depends on the genetic correlation of traits, which reflects the number of pleiotropic loci, i.e. genetic loci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8423f8a9deee97151aadd8c567bee9
https://ueaeprints.uea.ac.uk/id/eprint/73375/
https://ueaeprints.uea.ac.uk/id/eprint/73375/
Autor:
Bonnemaijer, Pieter W. M., Leeuwen, Elisabeth M. van, Iglesias, Adriana I., Gharahkhani, Puya, Vitart, Veronique, Khawaja, Anthony P., Simcoe, Mark, Hohn, Rene, Cree, Angela J., Igo, Rob P., International Glaucoma Genetics Consortium, NEIGHBORHOOD consortium, UK Biobank Eye and Vision Consortium, Barman, Sarah A., Gerhold-Ay, Aslihan, Nickels, Stefan, Wilson, James F., Hayward, Caroline, Boutin, Thibaud S., Polasek, Ozren, Aung, Tin, Khor, Chiea Chuen, Amin, Najaf, Lotery, Andrew J., Wiggs, Janey L., Cheng, Ching-Yu, Hysi, Pirro G., Hammond, Christopher J., Thiadens, Alberta A. H. J., MacGregor, Stuart, Klaver, Caroline C. W., Duijn, Cornelia M. van
Publikováno v:
Communications Biology
A new avenue of mining published genome-wide association studies includes the joint analysis of related traits. The power of this approach depends on the genetic correlation of traits, which reflects the number of pleiotropic loci, i.e. genetic loci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::048357a712879bb1d0587d16c24007a4
https://eprints.kingston.ac.uk/id/eprint/44683/1/Bonnemaijer-P-44683-VoR.pdf
https://eprints.kingston.ac.uk/id/eprint/44683/1/Bonnemaijer-P-44683-VoR.pdf
Autor:
Alward, Wallace LM, van der Heide, Carly, Khanna, Cheryl L, Roos, Ben R, Sivaprasad, Sobha, Kam, Jason, Ritch, Robert, Lotery, Andrew, Igo, Robert P, Cooke Bailey, Jessica N, Stone, Edwin M, Scheetz, Todd E, Kwon, Young H, Pasquale, Louis R, Wiggs, Janey L, Fingert, John H, NEIGHBORHOOD Consortium
Publikováno v:
JAMA ophthalmology, vol 137, iss 5
Importance:Mutations in the myocilin (MYOC) gene are the most common molecularly defined cause of primary open-angle glaucoma that typically occurs in patients with high intraocular pressures (IOP). One MYOC mutation, p.Gln368Ter, has been associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::f3ceae0d3be8f76c6a9813f95cab457b
https://escholarship.org/uc/item/5wg172mh
https://escholarship.org/uc/item/5wg172mh
Autor:
Iglesias, Adriana I, Mishra, Aniket, Vitart, Veronique, Bykhovskaya, Yelena, Höhn, René, Springelkamp, Henriët, Cuellar-Partida, Gabriel, Gharahkhani, Puya, Bailey, Jessica N Cooke, Willoughby, Colin E, Li, Xiaohui, Yazar, Seyhan, Nag, Abhishek, Khawaja, Anthony P, Polašek, Ozren, Siscovick, David, Mitchell, Paul, Tham, Yih Chung, Haines, Jonathan L, Kearns, Lisa S, Hayward, Caroline, Shi, Yuan, van Leeuwen, Elisabeth M, Taylor, Kent D, Blue Mountains Eye Study—GWAS group, Bonnemaijer, Pieter, Rotter, Jerome I, Martin, Nicholas G, Zeller, Tanja, Mills, Richard A, Souzeau, Emmanuelle, Staffieri, Sandra E, Jonas, Jost B, Schmidtmann, Irene, Boutin, Thibaud, Kang, Jae H, Lucas, Sionne EM, Wong, Tien Yin, Beutel, Manfred E, Wilson, James F, NEIGHBORHOOD Consortium, Wellcome Trust Case Control Consortium 2 (WTCCC2), Uitterlinden, André G, Vithana, Eranga N, Foster, Paul J, Hysi, Pirro G, Hewitt, Alex W, Khor, Chiea Chuen, Pasquale, Louis R, Montgomery, Grant W, Klaver, Caroline CW, Aung, Tin, Pfeiffer, Norbert, Mackey, David A, Hammond, Christopher J, Cheng, Ching-Yu, Craig, Jamie E, Rabinowitz, Yaron S, Wiggs, Janey L, Burdon, Kathryn P, van Duijn, Cornelia M, MacGregor, Stuart
Publikováno v:
Nature communications, vol 9, iss 1
Central corneal thickness (CCT) is a highly heritable trait associated with complex eye diseases such as keratoconus and glaucoma. We perform a genome-wide association meta-analysis of CCT and identify 19 novel regions. In addition to adding support
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::668be9ef24ca122fa58d2f84a9f44dc2
https://escholarship.org/uc/item/5bk0726x
https://escholarship.org/uc/item/5bk0726x
Autor:
King, Rebecca, Struebing, Felix L., Li, Ying, Wang, Jiaxing, Koch, Allison Ashley, Cooke Bailey, Jessica N., Gharahkhani, Puya, MacGregor, Stuart, Allingham, Rand, Hauser, Michael, Wiggs, Janey L., Geisert, Eldon E., Brilliant, Murray, Budenz, Don, Bailey, Jessica N.Cooke, Fingert, John, Gaasterland, Douglas, Gaasterland, Teresa, Haines, Jonathan L., Hark, Lisa, Igo, Rob, Kang, Jae Hee, Kraft, Peter, Lee, Richard, Lichter, Paul, Liu, Yutao, Moroi, Syoko, Pasquale, Louis R., Pericak-Vance, Margaret, Realini, Anthony, Rhee, Doug, Richards, Julia R., Ritch, Robert, Schuman, Joel, Scott, William K., Singh, Kuldev, Sit, Arthur, Vollrath, Douglas, Weinreb, Robert N., Wollstein, Gadi, Zack, Don, Aung, Tin, Burdon, Kathryn P., Cheng, Ching Yu, Craig, Jamie E., Cree, Angela J., Hammond, Christopher J.
Publikováno v:
PLoS Genetics, 14(1):e1007145. Public Library of Science
PLoS genetics, vol 14, iss 1
PLoS Genetics, Vol 14, Iss 1, p e1007145 (2018)
PLoS Genetics
PLoS genetics, vol 14, iss 1
PLoS Genetics, Vol 14, Iss 1, p e1007145 (2018)
PLoS Genetics
Central corneal thickness (CCT) is one of the most heritable ocular traits and it is also a phenotypic risk factor for primary open angle glaucoma (POAG). The present study uses the BXD Recombinant Inbred (RI) strains to identify novel quantitative t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f31d79ff99f00ae7be0acdaa10e2834
https://pure.eur.nl/en/publications/e4f26832-4193-4695-b82d-ebd7ebb9a785
https://pure.eur.nl/en/publications/e4f26832-4193-4695-b82d-ebd7ebb9a785
Autor:
Gao, Xiaoyi, Nannini, Drew R., Corrao, Kristen, Torres, Mina, Chen, Yii Der I., Fan, Bao J., Wiggs, Janey L., Taylor, Kent D., Gauderman, W. James, Rotter, Jerome I., Varma, Rohit, Aung, Tin, Burdon, Kathryn P., Cheng, Ching Yu, Craig, Jamie E., Cree, Angela J., Gharahkhani, Puya, Hammond, Christopher J., Hewitt, Alex W., Höhn, René, Hysi, Pirro, Gonzalez, Adriana I.Iglesias, Jonas, Jost, Khawaja, Anthony, Khor, Chiea Cheun, Klaver, Caroline C.W., Pasutto, Francesca, MacGregor, Stuart, Mackey, David, Mitchell, Paul, Mishra, Aniket, Pang, Calvin, Pasquale, Louis R., Springelkamp, Henriette, Thorleifsson, Gudmar, Thorsteinsdottir, Unnur, van Duijn, Cornelia M., Viswanathan, Ananth, Vitart, Veronique, Wojciechowski, Robert, Wong, Tien, Young, Terrri L., Zeller, Tanja
Publikováno v:
Human Molecular Genetics, 25(22), 5035-5045. Oxford University Press
The cornea is the outermost layer of the eye and is a vital component of focusing incoming light on the retina. Central corneal thickness (CCT) is now recognized to have a significant role in ocular health and is a risk factor for various ocular dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56628f52ed3ed866fa178f328fedabcf
https://europepmc.org/articles/PMC6078592/
https://europepmc.org/articles/PMC6078592/
Autor:
Springelkamp, Henriët., Höhn, René, Mishra, Aniket, Hysi, Pirro G., Khor, Chiea-Chuen, Loomis, Stephanie J., Bailey, Jessica N. Cooke, Gibson, Jane, Thorleifsson, Gudmar, Janssen, Sarah F., Luo, Xiaoyan, Ramdas, Wishal D., Vithana, Eranga, Nongpiur, Monisha E., Montgomery, Grant W., Xu, Liang, Mountain, Jenny E., Gharahkhani, Puya, Lu, Yi, Amin, Najaf, Karssen, Lennart C., Sim, Kar-Seng, van Leeuwen, Elisabeth M., Iglesias, Adriana I., Verhoeven, Virginie J. M., Hauser, Michael A., Loon, Seng-Chee, Despriet, Dominiek D. G., Nag, Abhishek, Venturini, Cristina, Sanfilippo, Paul G., Schillert, Arne, Kang, Jae H., Landers, John, Jonasson, Fridbert, Cree, Angela J., van Koolwijk, Leonieke M. E., Rivadeneira, Fernando, Souzeau, Emmanuelle, Jonsson, Vesteinn, Menon, Geeta, Mitchell, Paul, Wang, Jie Jin, Rochtchina, Elena, Attia, John, Scott, Rodney, Holliday, Elizabeth G., Wong, Tien-Yin, Baird, Paul N., Xie, Jing, Inouye, Michael, Viswanathan, Ananth, Sim, Xueling, Weinreb, Robert N., de Jong, Paulus T. V. M., Oostra, Ben A., Uitterlinden, André G., Hofman, Albert, Ennis, Sarah, Thorsteinsdottir, Unnur, Burdon, Kathryn P., Allingham, R. Rand, Brilliant, Murray H., Budenz, Donald L., Cooke Bailey, Jessica N., Christen, William G., Fingert, John, Friedman, David S., Gaasterland, Douglas, Gaasterland, Terry, Haines, Jonathan L., Kang, Jae Hee, Kraft, Peter, Lee, Richard K., Lichter, Paul R., Liu, Yutao, Moroi, Sayoko E., Pasquale, Louis R., Pericak-Vance, Margaret A., Realini, Anthony, Richards, Julia E., Schuman, Joel S., Scott, William K., Singh, Kuldev, Sit, Arthur J., Vollrath, Douglas, Wiggs, Janey L., Wollstein, Gadi, Zack, Donald J., Zhang, Kang, Donnelly (Chair), Peter, Barroso (Deputy Chair), Ines, Blackwell, Jenefer M., Bramon, Elvira, Brown, Matthew A., Casas, Juan P., Corvin, Aiden, Deloukas, Panos, Duncanson, Audrey, Jankowski, Janusz, Markus, Hugh S., Mathew, Christopher G., Palmer, Colin N. A., Plomin, Robert, Rautanen, Anna, Sawcer, Stephen J., Trembath, Richard C., Viswanathan, Ananth C., Wood, Nicholas W., Spencer, Chris C. A., Band, Gavin, Bellenguez, Céline, Freeman, Colin, Hellenthal, Garrett, Giannoulatou, Eleni, Pirinen, Matti, Pearson, Richard, Strange, Amy, Su, Zhan, Vukcevic, Damjan, Donnelly, Peter, Langford, Cordelia, Hunt, Sarah E., Edkins, Sarah, Gwilliam, Rhian, Blackburn, Hannah, Bumpstead, Suzannah J., Dronov, Serge, Gillman, Matthew, Gray, Emma, Hammond, Naomi, Jayakumar, Alagurevathi, McCann, Owen T., Liddle, Jennifer, Potter, Simon C., Ravindrarajah, Radhi, Ricketts, Michelle, Waller, Matthew, Weston, Paul, Widaa, Sara, Whittaker, Pamela, Barroso, Ines, Mathew (Chair), Christopher G., Spector, Timothy D., Mirshahi, Alireza, Saw, Seang-Mei, Vingerling, Johannes R., Teo, Yik-Ying, Wolfs, Roger C. W., Lemij, Hans G., Tai, E-Shyong, Jansonius, Nomdo M., Jonas, Jost B., Cheng, Ching-Yu, Aung, Tin, Klaver, Caroline C. W., Craig, Jamie E., Macgregor, Stuart, Mackey, David A., Lotery, Andrew J., Stefansson, Kari, Bergen, Arthur A. B., Young, Terri L., Pfeiffer, Norbert, Hewitt, Alex W., van Duijn, Cornelia M., Hammond, Christopher J.
Publikováno v:
Nature Communications
Nature communications, vol 5, iss 1
Nature Communications, 5. Nature Publishing Group
Nature Communications, 5:4883. Nature Publishing Group
Nature communications, 5. Nature Publishing Group
Nature Communications, 5
Nature communications, vol 5, iss 1
Nature Communications, 5. Nature Publishing Group
Nature Communications, 5:4883. Nature Publishing Group
Nature communications, 5. Nature Publishing Group
Nature Communications, 5
Glaucoma is characterized by irreversible optic nerve degeneration and is the most frequent cause of irreversible blindness worldwide. Here, the International Glaucoma Genetics Consortium conducts a meta-analysis of genome-wide association studies of
Autor:
Buys, Emmanuel S, Ko, Yu-Chien, Alt, Clemens, Hayton, Sarah R, Jones, Alexander, Tainsh, Laurel T, Ren, Ruiyi, Giani, Andrea, Clerté, Maeva, Abernathy, Emma, Tainsh, Robert ET, Oh, Dong-Jin, Malhotra, Rajeev, Arora, Pankaj, de Waard, Nadine, Yu, Binglan, Turcotte, Raphael, Nathan, Daniel, Scherrer-Crosbie, Marielle, Loomis, Stephanie J, Kang, Jae H, Lin, Charles P, Gong, Haiyan Y, Rhee, Douglas J, Brouckaert, Peter, Wiggs, Janey L, Gregory, Meredith S, Pasquale, Louis R, Bloch, Kenneth D, Ksander, Bruce R
Publikováno v:
PLOS ONE
Primary open angle glaucoma (POAG) is a leading cause of blindness worldwide. The molecular signaling involved in the pathogenesis of POAG remains unknown. Here, we report that mice lacking the alpha(1) subunit of the nitric oxide receptor soluble gu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______330::492a157dd4aeb09eeb5c516575f6599a
https://biblio.ugent.be/publication/3226647
https://biblio.ugent.be/publication/3226647
Autor:
Lee, Richard, Ulmer, Megan, Weinreb, Robert, Vollrath, Douglas, Richards, Julia E., Friedman, David S., Lichter, Paul, Liu, Yutao, Haines, Jonathan, Allingham, R. Rand, Yaspan, Brian L., Ashley-Koch, Allison, Zhang, Kang, Zack, Donald J., Realini, Anthony, Young, Terri, Kang, Jae H., Ozel, Ayse Bilge, Singh, Kuldev, Wiggs, Janey L., Wollstein, Gadi, Pericak-Vance, Margaret, Gaasterland, Douglas, Moroi, Sayoko E., Schuman, Joel S., Hawthorne, Felicia
To investigate the effects of central corneal thickness (CCT)-associated variants on primary open-angle glaucoma (POAG) risk using single nucleotide polymorphisms (SNP) data from the Glaucoma Genes and Environment (GLAUGEN) and National Eye Institute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b62cdd75e0dcccda3e81706f70c9b30c