Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Vincent W. Keng"'
Autor:
Stephen C. Schmechel, David A. Largaespada, Vincent W. Keng, Anthony E. Rizzardi, Margaret H. Collins, Colleen L. Forster, Amanda L. Halfond, Caitlin B. Conboy, Eric P. Rahrmann, Aaron L. Sarver, Andrew D. Greeley, Adrienne L. Watson, Nancy Ratner, Margaret R. Wallace, Leah K. Anderson, Kwangmin Choi, Branden S. Moriarity, Brian R. Wahl
Publikováno v:
Cancer Discovery. 3:674-689
Genetic changes required for the formation and progression of human Schwann cell tumors remain elusive. Using a Sleeping Beauty forward genetic screen, we identified several genes involved in canonical Wnt signaling as potential drivers of benign neu
Autor:
Christopher L. Moertel, Adrienne L. Watson, Vincent W. Keng, David A. Largaespada, Natalie K. Wolf, Bernat Gel, Dominic A. Beckmann, Margaret H. Collins, Eduard Serra, Margaret R. Wallace, Aaron L. Sarver, Branden S. Moriarity, Kwangmin Choi, Nancy Ratner, Eric P. Rahrmann
Publikováno v:
Nature genetics
Malignant peripheral nerve sheath tumors (MPNSTs) are sarcomas of Schwann cell lineage origin that occur sporadically or in association with the inherited syndrome neurofibromatosis type 1. To identify genetic drivers of MPNST development, we used th
Abstract 63: A transposon-based forward genetic screen for steatosis-associated liver cancer drivers
Publikováno v:
Cancer Research. 76:63-63
Hepatocellular carcinoma (HCC), or liver cancer, is the second leading cause of death from cancer worldwide (Ferlay et al, Lyon, France: International Agency for Research on Cancer, 2013). HCC is linked with hepatic steatosis, or fatty liver disease,
Autor:
Timothy P. Kuka, Jason B. Bell, Branden S. Moriarity, Vincent W. Keng, David A. Largaespada, Barbara R. Tschida
Publikováno v:
Cancer Research. 74:929-929
The role of zinc finger and BTB domain containing 20 (ZBTB20) in hepatocellular carcinoma (HCC) is not well defined, as there are many discrepancies in the literature regarding its role in liver tumorigenesis. ZBTB20 has been implicated to play a rol