Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Tim D. Spector"'
Autor:
Stavroula Kanoni, Sarah E. Graham, Yuxuan Wang, Ida Surakka, Shweta Ramdas, Xiang Zhu, Shoa L. Clarke, Konain Fatima Bhatti, Sailaja Vedantam, Thomas W. Winkler, Adam E. Locke, Eirini Marouli, Greg J. M. Zajac, Kuan-Han H. Wu, Ioanna Ntalla, Qin Hui, Derek Klarin, Austin T. Hilliard, Zeyuan Wang, Chao Xue, Gudmar Thorleifsson, Anna Helgadottir, Daniel F. Gudbjartsson, Hilma Holm, Isleifur Olafsson, Mi Yeong Hwang, Sohee Han, Masato Akiyama, Saori Sakaue, Chikashi Terao, Masahiro Kanai, Wei Zhou, Ben M. Brumpton, Humaira Rasheed, Aki S. Havulinna, Yogasudha Veturi, Jennifer Allen Pacheco, Elisabeth A. Rosenthal, Todd Lingren, QiPing Feng, Iftikhar J. Kullo, Akira Narita, Jun Takayama, Hilary C. Martin, Karen A. Hunt, Bhavi Trivedi, Jeffrey Haessler, Franco Giulianini, Yuki Bradford, Jason E. Miller, Archie Campbell, Kuang Lin, Iona Y. Millwood, Asif Rasheed, George Hindy, Jessica D. Faul, Wei Zhao, David R. Weir, Constance Turman, Hongyan Huang, Mariaelisa Graff, Ananyo Choudhury, Dhriti Sengupta, Anubha Mahajan, Michael R. Brown, Weihua Zhang, Ketian Yu, Ellen M. Schmidt, Anita Pandit, Stefan Gustafsson, Xianyong Yin, Jian’an Luan, Jing-Hua Zhao, Fumihiko Matsuda, Hye-Mi Jang, Kyungheon Yoon, Carolina Medina-Gomez, Achilleas Pitsillides, Jouke Jan Hottenga, Andrew R. Wood, Yingji Ji, Zishan Gao, Simon Haworth, Noha A. Yousri, Ruth E. Mitchell, Jin Fang Chai, Mette Aadahl, Anne A. Bjerregaard, Jie Yao, Ani Manichaikul, Chii-Min Hwu, Yi-Jen Hung, Helen R. Warren, Julia Ramirez, Jette Bork-Jensen, Line L. Kårhus, Anuj Goel, Maria Sabater-Lleal, Raymond Noordam, Pala Mauro, Floris Matteo, Aaron F. McDaid, Pedro Marques-Vidal, Matthias Wielscher, Stella Trompet, Naveed Sattar, Line T. Møllehave, Matthias Munz, Lingyao Zeng, Jianfeng Huang, Bin Yang, Alaitz Poveda, Azra Kurbasic, Claudia Lamina, Lukas Forer, Markus Scholz, Tessel E. Galesloot, Jonathan P. Bradfield, Sanni E. Ruotsalainen, EWarwick Daw, Joseph M. Zmuda, Jonathan S. Mitchell, Christian Fuchsberger, Henry Christensen, Jennifer A. Brody, Miguel Vazquez-Moreno, Mary F. Feitosa, Mary K. Wojczynski, Zhe Wang, Michael H. Preuss, Massimo Mangino, Paraskevi Christofidou, Niek Verweij, Jan W. Benjamins, Jorgen Engmann, Noah L. Tsao, Anurag Verma, Roderick C. Slieker, Ken Sin Lo, Nuno R. Zilhao, Phuong Le, Marcus E. Kleber, Graciela E. Delgado, Shaofeng Huo, Daisuke D. Ikeda, Hiroyuki Iha, Jian Yang, Jun Liu, Ayşe Demirkan, Hampton L. Leonard, Jonathan Marten, Mirjam Frank, Börge Schmidt, Laura J. Smyth, Marisa Cañadas-Garre, Chaolong Wang, Masahiro Nakatochi, Andrew Wong, Nina Hutri-Kähönen, Xueling Sim, Rui Xia, Alicia Huerta-Chagoya, Juan Carlos Fernandez-Lopez, Valeriya Lyssenko, Suraj S. Nongmaithem, Swati Bayyana, Heather M. Stringham, Marguerite R. Irvin, Christopher Oldmeadow, Han-Na Kim, Seungho Ryu, Paul R. H. J. Timmers, Liubov Arbeeva, Rajkumar Dorajoo, Leslie A. Lange, Gauri Prasad, Laura Lorés-Motta, Marc Pauper, Jirong Long, Xiaohui Li, Elizabeth Theusch, Fumihiko Takeuchi, Cassandra N. Spracklen, Anu Loukola, Sailalitha Bollepalli, Sophie C. Warner, Ya Xing Wang, Wen B. Wei, Teresa Nutile, Daniela Ruggiero, Yun Ju Sung, Shufeng Chen, Fangchao Liu, Jingyun Yang, Katherine A. Kentistou, Bernhard Banas, Giuseppe Giovanni Nardone, Karina Meidtner, Lawrence F. Bielak, Jennifer A. Smith, Prashantha Hebbar, Aliki-Eleni Farmaki, Edith Hofer, Maoxuan Lin, Maria Pina Concas, Simona Vaccargiu, Peter J. van der Most, Niina Pitkänen, Brian E. Cade, Sander W. van der Laan, Kumaraswamy Naidu Chitrala, Stefan Weiss, Amy R. Bentley, Ayo P. Doumatey, Adebowale A. Adeyemo, Jong Young Lee, Eva R. B. Petersen, Aneta A. Nielsen, Hyeok Sun Choi, Maria Nethander, Sandra Freitag-Wolf, Lorraine Southam, Nigel W. Rayner, Carol A. Wang, Shih-Yi Lin, Jun-Sing Wang, Christian Couture, Leo-Pekka Lyytikäinen, Kjell Nikus, Gabriel Cuellar-Partida, Henrik Vestergaard, Bertha Hidalgo, Olga Giannakopoulou, Qiuyin Cai, Morgan O. Obura, Jessica van Setten, Xiaoyin Li, Jingjing Liang, Hua Tang, Natalie Terzikhan, Jae Hun Shin, Rebecca D. Jackson, Alexander P. Reiner, Lisa Warsinger Martin, Zhengming Chen, Liming Li, Takahisa Kawaguchi, Joachim Thiery, Joshua C. Bis, Lenore J. Launer, Huaixing Li, Mike A. Nalls, Olli T. Raitakari, Sahoko Ichihara, Sarah H. Wild, Christopher P. Nelson, Harry Campbell, Susanne Jäger, Toru Nabika, Fahd Al-Mulla, Harri Niinikoski, Peter S. Braund, Ivana Kolcic, Peter Kovacs, Tota Giardoglou, Tomohiro Katsuya, Dominique de Kleijn, Gert J. de Borst, Eung Kweon Kim, Hieab H. H. Adams, M. Arfan Ikram, Xiaofeng Zhu, Folkert W. Asselbergs, Adriaan O. Kraaijeveld, Joline W. J. Beulens, Xiao-Ou Shu, Loukianos S. Rallidis, Oluf Pedersen, Torben Hansen, Paul Mitchell, Alex W. Hewitt, Mika Kähönen, Louis Pérusse, Claude Bouchard, Anke Tönjes, Yii-Der Ida Chen, Craig E. Pennell, Trevor A. Mori, Wolfgang Lieb, Andre Franke, Claes Ohlsson, Dan Mellström, Yoon Shin Cho, Hyejin Lee, Jian-Min Yuan, Woon-Puay Koh, Sang Youl Rhee, Jeong-Taek Woo, Iris M. Heid, Klaus J. Stark, Martina E. Zimmermann, Henry Völzke, Georg Homuth, Michele K. Evans, Alan B. Zonderman, Ozren Polasek, Gerard Pasterkamp, Imo E. Hoefer, Susan Redline, Katja Pahkala, Albertine J. Oldehinkel, Harold Snieder, Ginevra Biino, Reinhold Schmidt, Helena Schmidt, Stefania Bandinelli, George Dedoussis, Thangavel Alphonse Thanaraj, Sharon L. R. Kardia, Patricia A. Peyser, Norihiro Kato, Matthias B. Schulze, Giorgia Girotto, Carsten A. Böger, Bettina Jung, Peter K. Joshi, David A. Bennett, Philip L. De Jager, Xiangfeng Lu, Vasiliki Mamakou, Morris Brown, Mark J. Caulfield, Patricia B. Munroe, Xiuqing Guo, Marina Ciullo, Jost B. Jonas, Nilesh J. Samani, Jaakko Kaprio, Päivi Pajukanta, Teresa Tusié-Luna, Carlos A. Aguilar-Salinas, Linda S. Adair, Sonny Augustin Bechayda, H. Janaka de Silva, Ananda R. Wickremasinghe, Ronald M. Krauss, Jer-Yuarn Wu, Wei Zheng, Anneke Iden Hollander, Dwaipayan Bharadwaj, Adolfo Correa, James G. Wilson, Lars Lind, Chew-Kiat Heng, Amanda E. Nelson, Yvonne M. Golightly, James F. Wilson, Brenda Penninx, Hyung-Lae Kim, John Attia, Rodney J. Scott, D. C. Rao, Donna K. Arnett, Steven C. Hunt, Mark Walker, Heikki A. Koistinen, Giriraj R. Chandak, Josep M. Mercader, Maria C. Costanzo, Dongkeun Jang, Noël P. Burtt, Clicerio Gonzalez Villalpando, Lorena Orozco, Myriam Fornage, EShyong Tai, Rob M. van Dam, Terho Lehtimäki, Nish Chaturvedi, Mitsuhiro Yokota, Jianjun Liu, Dermot F. Reilly, Amy Jayne McKnight, Frank Kee, Karl-Heinz Jöckel, Mark I. McCarthy, Colin N. A. Palmer, Veronique Vitart, Caroline Hayward, Eleanor Simonsick, Cornelia M. van Duijn, Zi-Bing Jin, Jia Qu, Haretsugu Hishigaki, Xu Lin, Winfried März, Vilmundur Gudnason, Jean-Claude Tardif, Guillaume Lettre, Leen M.‘t Hart, Petra J. M. Elders, Scott M. Damrauer, Meena Kumari, Mika Kivimaki, Pim van der Harst, Tim D. Spector, Ruth J. F. Loos, Michael A. Province, Esteban J. Parra, Miguel Cruz, Bruce M. Psaty, Ivan Brandslund, Peter P. Pramstaller, Charles N. Rotimi, Kaare Christensen, Samuli Ripatti, Elisabeth Widén, Hakon Hakonarson, Struan F. A. Grant, Lambertus A. L. M. Kiemeney, Jacqueline de Graaf, Markus Loeffler, Florian Kronenberg, Dongfeng Gu, Jeanette Erdmann, Heribert Schunkert, Paul W. Franks, Allan Linneberg, J. Wouter Jukema, Amit V. Khera, Minna Männikkö, Marjo-Riitta Jarvelin, Zoltan Kutalik, Cucca Francesco, Dennis O. Mook-Kanamori, Ko Willems van Dijk, Hugh Watkins, David P. Strachan, Niels Grarup, Peter Sever, Neil Poulter, Lee-Ming Chuang, Jerome I. Rotter, Thomas M. Dantoft, Fredrik Karpe, Matt J. Neville, Nicholas J. Timpson, Ching-Yu Cheng, Tien-Yin Wong, Chiea Chuen Khor, Hengtong Li, Charumathi Sabanayagam, Annette Peters, Christian Gieger, Andrew T. Hattersley, Nancy L. Pedersen, Patrik K. E. Magnusson, Dorret I. Boomsma, Allegonda H. M. Willemsen, LAdrienne Cupples, Joyce B. J. van Meurs, Mohsen Ghanbari, Penny Gordon-Larsen, Wei Huang, Young Jin Kim, Yasuharu Tabara, Nicholas J. Wareham, Claudia Langenberg, Eleftheria Zeggini, Johanna Kuusisto, Markku Laakso, Erik Ingelsson, Goncalo Abecasis, John C. Chambers, Jaspal S. Kooner, Paul S. de Vries, Alanna C. Morrison, Scott Hazelhurst, Michèle Ramsay, Kari E. North, Martha Daviglus, Peter Kraft, Nicholas G. Martin, John B. Whitfield, Shahid Abbas, Danish Saleheen, Robin G. Walters, Michael V. Holmes, Corri Black, Blair H. Smith, Aris Baras, Anne E. Justice, Julie E. Buring, Paul M. Ridker, Daniel I. Chasman, Charles Kooperberg, Gen Tamiya, Masayuki Yamamoto, David A. van Heel, Richard C. Trembath, Wei-Qi Wei, Gail P. Jarvik, Bahram Namjou, M. Geoffrey Hayes, Marylyn D. Ritchie, Pekka Jousilahti, Veikko Salomaa, Kristian Hveem, Bjørn Olav Åsvold, Michiaki Kubo, Yoichiro Kamatani, Yukinori Okada, Yoshinori Murakami, Bong-Jo Kim, Unnur Thorsteinsdottir, Kari Stefansson, Jifeng Zhang, YEugene Chen, Yuk-Lam Ho, Julie A. Lynch, Daniel J. Rader, Philip S. Tsao, Kyong-Mi Chang, Kelly Cho, Christopher J. O’Donnell, John M. Gaziano, Peter W. F. Wilson, Timothy M. Frayling, Joel N. Hirschhorn, Sekar Kathiresan, Karen L. Mohlke, Yan V. Sun, Andrew P. Morris, Michael Boehnke, Christopher D. Brown, Pradeep Natarajan, Panos Deloukas, Cristen J. Willer, Themistocles L. Assimes, Gina M. Peloso
Publikováno v:
Genome Biology, 23(1):268. Springer Verlag
Genome Biology, 23:268. BMC
Genome biology, vol. 23, no. 1, pp. 268
Kanoni, S, Graham, S E, Wang, Y, Surakka, I, Ramdas, S, Zhu, X, Clarke, S L, Bhatti, K F, Vedantam, S, Winkler, T W, Locke, A E, Marouli, E, Zajac, G J M, Wu, K-H H, Ntalla, I, Hui, Q, Klarin, D, Hilliard, A T, Wang, Z, Xue, C, Thorleifsson, G, Helgadottir, A, Gudbjartsson, D F, Holm, H, Olafsson, I, Hwang, M Y, Han, S, Akiyama, M, Sakaue, S, Terao, C, Kanai, M, Zhou, W, Brumpton, B M, Rasheed, H, Havulinna, A S, Veturi, Y, Pacheco, J A, Rosenthal, E A, Lingren, T, Feng, Q, Kullo, I J, Narita, A, Takayama, J, Martin, H C, Hunt, K A, Trivedi, B, Haessler, J, Giulianini, F, Bradford, Y, Miller, J E, Campbell, A, Lin, K, Millwood, I Y, Rasheed, A, Hindy, G, Faul, J D, Zhao, W, Weir, D R, Turman, C, Huang, H, Graff, M, Choudhury, A, Sengupta, D, Mahajan, A, Brown, M R, Zhang, W, Yu, K, Schmidt, E M, Pandit, A, Gustafsson, S, Yin, X, Luan, J, Zhao, J-H, Matsuda, F, Jang, H-M, Yoon, K, Medina-Gomez, C, Pitsillides, A, Hottenga, J J, Wood, A R, Ji, Y, Gao, Z, Haworth, S, Yousri, N A, Mitchell, R E, Chai, J F, Aadahl, M, Bjerregaard, A A, Yao, J, Manichaikul, A, Hwu, C-M, Hung, Y-J, Warren, H R, Ramirez, J, Bork-Jensen, J, Kårhus, L L, Goel, A, Sabater-Lleal, M, Noordam, R, Mauro, P, Matteo, F, McDaid, A F, Marques-Vidal, P, Wielscher, M, Trompet, S, Sattar, N, Møllehave, L T, Munz, M, Zeng, L, Huang, J, Yang, B, Poveda, A, Kurbasic, A, Lamina, C, Forer, L, Scholz, M, Galesloot, T E, Bradfield, J P, Ruotsalainen, S E, Daw, EW, Zmuda, J M, Mitchell, J S, Fuchsberger, C, Christensen, H, Brody, J A, Vazquez-Moreno, M, Feitosa, M F, Wojczynski, M K, Wang, Z, Preuss, M H, Mangino, M, Christofidou, P, Verweij, N, Benjamins, J W, Engmann, J, Tsao, N L, Verma, A, Slieker, R C, Lo, K S, Zilhao, N R, Le, P, Kleber, M E, Delgado, G E, Huo, S, Ikeda, D D, Iha, H, Yang, J, Liu, J, Demirkan, A, Leonard, H L, Marten, J, Frank, M, Schmidt, B, Smyth, L J, Cañadas-Garre, M, Wang, C, Nakatochi, M, Wong, A, Hutri-Kähönen, N, Sim, X, Xia, R, Huerta-Chagoya, A, Fernandez-Lopez, J C, Lyssenko, V, Nongmaithem, S S, Bayyana, S, Stringham, H M, Irvin, M R, Oldmeadow, C, Kim, H-N, Ryu, S, Timmers, P R H J, Arbeeva, L, Dorajoo, R, Lange, L A, Prasad, G, Lorés-Motta, L, Pauper, M, Long, J, Li, X, Theusch, E, Takeuchi, F, Spracklen, C N, Loukola, A, Bollepalli, S, Warner, S C, Wang, Y X, Wei, W B, Nutile, T, Ruggiero, D, Sung, Y J, Chen, S, Liu, F, Yang, J, Kentistou, K A, Banas, B, Nardone, G G, Meidtner, K, Bielak, L F, Smith, J A, Hebbar, P, Farmaki, A-E, Hofer, E, Lin, M, Concas, M P, Vaccargiu, S, van der Most, P J, Pitkänen, N, Cade, B E, van der Laan, S W, Chitrala, K N, Weiss, S, Bentley, A R, Doumatey, A P, Adeyemo, A A, Lee, J Y, Petersen, E R B, Nielsen, A A, Choi, H S, Nethander, M, Freitag-Wolf, S, Southam, L, Rayner, N W, Wang, C A, Lin, S-Y, Wang, J-S, Couture, C, Lyytikäinen, L-P, Nikus, K, Cuellar-Partida, G, Vestergaard, H, Hidalgo, B, Giannakopoulou, O, Cai, Q, Obura, M O, van Setten, J, Li, X, Liang, J, Tang, H, Terzikhan, N, Shin, J H, Jackson, R D, Reiner, A P, Martin, L W, Chen, Z, Li, L, Kawaguchi, T, Thiery, J, Bis, J C, Launer, L J, Li, H, Nalls, M A, Raitakari, O T, Ichihara, S, Wild, S H, Nelson, C P, Campbell, H, Jäger, S, Nabika, T, Al-Mulla, F, Niinikoski, H, Braund, P S, Kolcic, I, Kovacs, P, Giardoglou, T, Katsuya, T, de Kleijn, D, de Borst, G J, Kim, E K, Adams, H H H, Ikram, M A, Zhu, X, Asselbergs, F W, Kraaijeveld, A O, Beulens, J W J, Shu, X-O, Rallidis, L S, Pedersen, O, Hansen, T, Mitchell, P, Hewitt, A W, Kähönen, M, Pérusse, L, Bouchard, C, Tönjes, A, Chen, Y-D I, Pennell, C E, Mori, T A, Lieb, W, Franke, A, Ohlsson, C, Mellström, D, Cho, Y S, Lee, H, Yuan, J-M, Koh, W-P, Rhee, S Y, Woo, J-T, Heid, I M, Stark, K J, Zimmermann, M E, Völzke, H, Homuth, G, Evans, M K, Zonderman, A B, Polasek, O, Pasterkamp, G, Hoefer, I E, Redline, S, Pahkala, K, Oldehinkel, A J, Snieder, H, Biino, G, Schmidt, R, Schmidt, H, Bandinelli, S, Dedoussis, G, Thanaraj, T A, Kardia, S L R, Peyser, P A, Kato, N, Schulze, M B, Girotto, G, Böger, C A, Jung, B, Joshi, P K, Bennett, D A, De Jager, P L, Lu, X, Mamakou, V, Brown, M, Caulfield, M J, Munroe, P B, Guo, X, Ciullo, M, Jonas, J B, Samani, N J, Kaprio, J, Pajukanta, P, Tusié-Luna, T, Aguilar-Salinas, C A, Adair, L S, Bechayda, S A, de Silva, H J, Wickremasinghe, A R, Krauss, R M, Wu, J-Y, Zheng, W, Hollander, A I, Bharadwaj, D, Correa, A, Wilson, J G, Lind, L, Heng, C-K, Nelson, A E, Golightly, Y M, Wilson, J G, Penninx, B, Kim, H-L, Attia, J, Scott, R J, Rao, D C, Arnett, D K, Hunt, S C, Walker, M, Koistinen, H A, Chandak, G R, Mercader, J M, Costanzo, M C, Jang, D, Burtt, N P, Villalpando, C G, Orozco, L, Fornage, M, Tai, ES, van Dam, R M, Lehtimäki, T, Chaturvedi, N, Yokota, M, Liu, J, Reilly, D F, McKnight, A J, Kee, F, Jöckel, K-H, McCarthy, M I, Palmer, C N A, Vitart, V, Hayward, C, Simonsick, E, van Duijn, C M, Jin, Z-B, Qu, J, Hishigaki, H, Lin, X, März, W, Gudnason, V, Tardif, J-C, Lettre, G, Hart, L M, Elders, P J M, Damrauer, S M, Kumari, M, Kivimaki, M, van der Harst, P, Spector, T D, Loos, R J F, Province, M A, Parra, E J, Cruz, M, Psaty, B M, Brandslund, I, Pramstaller, P P, Rotimi, C N, Christensen, K, Ripatti, S, Widén, E, Hakonarson, H, Grant, S F A, Kiemeney, L A L M, de Graaf, J, Loeffler, M, Kronenberg, F, Gu, D, Erdmann, J, Schunkert, H, Franks, P W, Linneberg, A, Jukema, J W, Khera, A V, Männikkö, M, Jarvelin, M-R, Kutalik, Z, Francesco, C, Mook-Kanamori, D O, van Dijk, K W, Watkins, H, Strachan, D P, Grarup, N, Sever, P, Poulter, N, Chuang, L-M, Rotter, J I, Dantoft, T M, Karpe, F, Neville, M J, Timpson, N J, Cheng, C-Y, Wong, T-Y, Khor, C C, Li, H, Sabanayagam, C, Peters, A, Gieger, C, Hattersley, A T, Pedersen, N L, Magnusson, P K E, Boomsma, D I, Willemsen, A H M, Cupples, LA, van Meurs, J B J, Ghanbari, M, Gordon-Larsen, P, Huang, W, Kim, Y J, Tabara, Y, Wareham, N J, Langenberg, C, Zeggini, E, Kuusisto, J, Laakso, M, Ingelsson, E, Abecasis, G, Chambers, J C, Kooner, J S, de Vries, P S, Morrison, A C, Hazelhurst, S, Ramsay, M, North, K E, Daviglus, M, Kraft, P, Martin, N G, Whitfield, J B, Abbas, S, Saleheen, D, Walters, R G, Holmes, M V, Black, C, Smith, B H, Baras, A, Justice, A E, Buring, J E, Ridker, P M, Chasman, D I, Kooperberg, C, Tamiya, G, Yamamoto, M, van Heel, D A, Trembath, R C, Wei, W-Q, Jarvik, G P, Namjou, B, Hayes, M G, Ritchie, M D, Jousilahti, P, Salomaa, V, Hveem, K, Åsvold, B O, Kubo, M, Kamatani, Y, Okada, Y, Murakami, Y, Kim, B-J, Thorsteinsdottir, U, Stefansson, K, Zhang, J, Chen, YE, Ho, Y-L, Lynch, J A, Rader, D J, Tsao, P S, Chang, K-M, Cho, K, O'Donnell, C J, Gaziano, J M, Wilson, P W F, Frayling, T M, Hirschhorn, J N, Kathiresan, S, Mohlke, K L, Sun, Y V, Morris, A P, Boehnke, M, Brown, C D, Natarajan, P, Deloukas, P, Willer, C J, Assimes, T L & Peloso, G M 2022, ' Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ', Genome Biology, vol. 23, no. 1, pp. 268 . https://doi.org/10.1186/s13059-022-02837-1
Kanoni, S, Graham, S E, Wang, Y, Surakka, I, Brumpton, B M, Rasheed, H, Haworth, S, Mitchell, R E, Wong, A, Timpson, N J, Zeggini, E, Willer, C J & Peloso, G M & et, A 2022, ' Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ', Genome Biology, vol. 23, no. 1, 268 . https://doi.org/10.1186/s13059-022-02837-1
Kanoni, S, Graham, S E, Wang, Y, Surakka, I, Ramdas, S, Zhu, X, Clarke, S L, Bhatti, K F, Vedantam, S, Winkler, T W, Locke, A E, Marouli, E, Zajac, G J M, Wu, K-H H, Ntalla, I, Hui, Q, Klarin, D, Hilliard, A T, Wang, Z, Xue, C, Thorleifsson, G, Helgadottir, A, Gudbjartsson, D F, Holm, H, Olafsson, I, Hwang, M Y, Han, S, Akiyama, M, Sakaue, S, Terao, C, Kanai, M, Zhou, W, Brumpton, B M, Rasheed, H, Havulinna, A S, Veturi, Y, Pacheco, J A, Rosenthal, E A, Lingren, T, Feng, Q, Kullo, I J, Narita, A, Takayama, J, Martin, H C, Hunt, K A, Trivedi, B, Haessler, J, Giulianini, F, Bradford, Y, Miller, J E, Campbell, A, Lin, K, Millwood, I Y, Rasheed, A, Hindy, G, Faul, J D, Zhao, W, Weir, D R, Turman, C, Huang, H, Graff, M, Choudhury, A, Sengupta, D, Mahajan, A, Brown, M R, Zhang, W, Yu, K, Schmidt, E M, Pandit, A, Gustafsson, S, Yin, X, Luan, J, Zhao, J-H, Matsuda, F, Jang, H-M, Yoon, K, Medina-Gomez, C, Pitsillides, A, Hottenga, J J, Wood, A R, Ji, Y, Gao, Z, Haworth, S, Yousri, N A, Mitchell, R E, Chai, J F, Aadahl, M, Bjerregaard, A A, Yao, J, Manichaikul, A, Hwu, C-M, Hung, Y-J, Warren, H R, Ramirez, J, Bork-Jensen, J, Kårhus, L L, Goel, A, Sabater-Lleal, M, Noordam, R, Mauro, P, Matteo, F, McDaid, A F, Marques-Vidal, P, Wielscher, M, Trompet, S, Sattar, N, Møllehave, L T, Munz, M, Zeng, L, Huang, J, Yang, B, Poveda, A, Kurbasic, A, Lamina, C, Forer, L, Scholz, M, Galesloot, T E, Bradfield, J P, Ruotsalainen, S E, Daw, EW, Zmuda, J M, Mitchell, J S, Fuchsberger, C, Christensen, H, Brody, J A, Vazquez-Moreno, M, Feitosa, M F, Wojczynski, M K, Wang, Z, Preuss, M H, Mangino, M, Christofidou, P, Verweij, N, Benjamins, J W, Engmann, J, Tsao, N L, Verma, A, Slieker, R C, Lo, K S, Zilhao, N R, Le, P, Kleber, M E, Delgado, G E, Huo, S, Ikeda, D D, Iha, H, Yang, J, Liu, J, Demirkan, A, Leonard, H L, Marten, J, Frank, M, Schmidt, B, Smyth, L J, Cañadas-Garre, M, Wang, C, Nakatochi, M, Wong, A, Hutri-Kähönen, N, Sim, X, Xia, R, Huerta-Chagoya, A, Fernandez-Lopez, J C, Lyssenko, V, Nongmaithem, S S, Bayyana, S, Stringham, H M, Irvin, M R, Oldmeadow, C, Kim, H-N, Ryu, S, Timmers, P R H J, Arbeeva, L, Dorajoo, R, Lange, L A, Prasad, G, Lorés-Motta, L, Pauper, M, Long, J, Li, X, Theusch, E, Takeuchi, F, Spracklen, C N, Loukola, A, Bollepalli, S, Warner, S C, Wang, Y X, Wei, W B, Nutile, T, Ruggiero, D, Sung, Y J, Chen, S, Liu, F, Yang, J, Kentistou, K A, Banas, B, Nardone, G G, Meidtner, K, Bielak, L F, Smith, J A, Hebbar, P, Farmaki, A-E, Hofer, E, Lin, M, Concas, M P, Vaccargiu, S, van der Most, P J, Pitkänen, N, Cade, B E, van der Laan, S W, Chitrala, K N, Weiss, S, Bentley, A R, Doumatey, A P, Adeyemo, A A, Lee, J Y, Petersen, E R B, Nielsen, A A, Choi, H S, Nethander, M, Freitag-Wolf, S, Southam, L, Rayner, N W, Wang, C A, Lin, S-Y, Wang, J-S, Couture, C, Lyytikäinen, L-P, Nikus, K, Cuellar-Partida, G, Vestergaard, H, Hidalgo, B, Giannakopoulou, O, Cai, Q, Obura, M O, van Setten, J, Li, X, Liang, J, Tang, H, Terzikhan, N, Shin, J H, Jackson, R D, Reiner, A P, Martin, L W, Chen, Z, Li, L, Kawaguchi, T, Thiery, J, Bis, J C, Launer, L J, Li, H, Nalls, M A, Raitakari, O T, Ichihara, S, Wild, S H, Nelson, C P, Campbell, H, Jäger, S, Nabika, T, Al-Mulla, F, Niinikoski, H, Braund, P S, Kolcic, I, Kovacs, P, Giardoglou, T, Katsuya, T, de Kleijn, D, de Borst, G J, Kim, E K, Adams, H H H, Ikram, M A, Zhu, X, Asselbergs, F W, Kraaijeveld, A O, Beulens, J W J, Shu, X-O, Rallidis, L S, Pedersen, O, Hansen, T, Mitchell, P, Hewitt, A W, Kähönen, M, Pérusse, L, Bouchard, C, Tönjes, A, Chen, Y-D I, Pennell, C E, Mori, T A, Lieb, W, Franke, A, Ohlsson, C, Mellström, D, Cho, Y S, Lee, H, Yuan, J-M, Koh, W-P, Rhee, S Y, Woo, J-T, Heid, I M, Stark, K J, Zimmermann, M E, Völzke, H, Homuth, G, Evans, M K, Zonderman, A B, Polasek, O, Pasterkamp, G, Hoefer, I E, Redline, S, Pahkala, K, Oldehinkel, A J, Snieder, H, Biino, G, Schmidt, R, Schmidt, H, Bandinelli, S, Dedoussis, G, Thanaraj, T A, Kardia, S L R, Peyser, P A, Kato, N, Schulze, M B, Girotto, G, Böger, C A, Jung, B, Joshi, P K, Bennett, D A, De Jager, P L, Lu, X, Mamakou, V, Brown, M, Caulfield, M J, Munroe, P B, Guo, X, Ciullo, M, Jonas, J B, Samani, N J, Kaprio, J, Pajukanta, P, Tusié-Luna, T, Aguilar-Salinas, C A, Adair, L S, Bechayda, S A, de Silva, H J, Wickremasinghe, A R, Krauss, R M, Wu, J-Y, Zheng, W, Hollander, A I, Bharadwaj, D, Correa, A, Wilson, J G, Lind, L, Heng, C-K, Nelson, A E, Golightly, Y M, Wilson, J F, Penninx, B, Kim, H-L, Attia, J, Scott, R J, Rao, D C, Arnett, D K, Hunt, S C, Walker, M, Koistinen, H A, Chandak, G R, Mercader, J M, Costanzo, M C, Jang, D, Burtt, N P, Villalpando, C G, Orozco, L, Fornage, M, Tai, ES, van Dam, R M, Lehtimäki, T, Chaturvedi, N, Yokota, M, Liu, J, Reilly, D F, McKnight, A J, Kee, F, Jöckel, K-H, McCarthy, M I, Palmer, C N A, Vitart, V, Hayward, C, Simonsick, E, van Duijn, C M, Jin, Z-B, Qu, J, Hishigaki, H, Lin, X, März, W, Gudnason, V, Tardif, J-C, Lettre, G, Hart, L M, Elders, P J M, Damrauer, S M, Kumari, M, Kivimaki, M, van der Harst, P, Spector, T D, Loos, R J F, Province, M A, Parra, E J, Cruz, M, Psaty, B M, Brandslund, I, Pramstaller, P P, Rotimi, C N, Christensen, K, Ripatti, S, Widén, E, Hakonarson, H, Grant, S F A, Kiemeney, L A L M, de Graaf, J, Loeffler, M, Kronenberg, F, Gu, D, Erdmann, J, Schunkert, H, Franks, P W, Linneberg, A, Jukema, J W, Khera, A V, Männikkö, M, Jarvelin, M-R, Kutalik, Z, Francesco, C, Mook-Kanamori, D O, van Dijk, K W, Watkins, H, Strachan, D P, Grarup, N, Sever, P, Poulter, N, Chuang, L-M, Rotter, J I, Dantoft, T M, Karpe, F, Neville, M J, Timpson, N J, Cheng, C-Y, Wong, T-Y, Khor, C C, Li, H, Sabanayagam, C, Peters, A, Gieger, C, Hattersley, A T, Pedersen, N L, Magnusson, P K E, Boomsma, D I, Willemsen, A H M, Cupples, LA, van Meurs, J B J, Ghanbari, M, Gordon-Larsen, P, Huang, W, Kim, Y J, Tabara, Y, Wareham, N J, Langenberg, C, Zeggini, E, Kuusisto, J, Laakso, M, Ingelsson, E, Abecasis, G, Chambers, J C, Kooner, J S, de Vries, P S, Morrison, A C, Hazelhurst, S, Ramsay, M, North, K E, Daviglus, M, Kraft, P, Martin, N G, Whitfield, J B, Abbas, S, Saleheen, D, Walters, R G, Holmes, M V, Black, C, Smith, B H, Baras, A, Justice, A E, Buring, J E, Ridker, P M, Chasman, D I, Kooperberg, C, Tamiya, G, Yamamoto, M, van Heel, D A, Trembath, R C, Wei, W-Q, Jarvik, G P, Namjou, B, Hayes, M G, Ritchie, M D, Jousilahti, P, Salomaa, V, Hveem, K, Åsvold, B O, Kubo, M, Kamatani, Y, Okada, Y, Murakami, Y, Kim, B-J, Thorsteinsdottir, U, Stefansson, K, Zhang, J, Chen, YE, Ho, Y-L, Lynch, J A, Rader, D J, Tsao, P S, Chang, K-M, Cho, K, O'Donnell, C J, Gaziano, J M, Wilson, P W F, Frayling, T M, Hirschhorn, J N, Kathiresan, S, Mohlke, K L, Sun, Y V, Morris, A P, Boehnke, M, Natarajan, P, Deloukas, P, Willer, C J, Assimes, T L & Peloso, G M 2022, ' Implicating genes, pleiotropy and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ', Genome biology, vol. 23, no. 1, 268 . https://doi.org/10.1186/s13059-022-02837-1
Kanoni, S, Graham, S E, Wang, Y, Surakka, I, Ramdas, S, Zhu, X, Clarke, S L, Bhatti, K F, Vedantam, S, Winkler, T W, Locke, A E, Marouli, E, Zajac, G J M, Wu, K H H, Ntalla, I, Hui, Q, Klarin, D, Hilliard, A T, Wang, Z, Xue, C, Thorleifsson, G, Helgadottir, A, Gudbjartsson, D F, Holm, H, Olafsson, I, Hwang, M Y, Han, S, Akiyama, M, Sakaue, S, Terao, C, Kanai, M, Zhou, W, Brumpton, B M, Rasheed, H, Havulinna, A S, Veturi, Y, Pacheco, J A, Rosenthal, E A, Lingren, T, Feng, Q P, Kullo, I J, Narita, A, Takayama, J, Martin, H C, Hunt, K A, Trivedi, B, Haessler, J, Giulianini, F, Bradford, Y, Miller, J E, Campbell, A, Lin, K, Millwood, I Y, Rasheed, A, Hindy, G, Faul, J D, Zhao, W, Weir, D R, Turman, C, Huang, H, Graff, M, Choudhury, A, Sengupta, D, Mahajan, A, Brown, M R, Zhang, W, Yu, K, Schmidt, E M, Pandit, A, Gustafsson, S, Yin, X, Luan, J, Zhao, J H, Matsuda, F, Jang, H M, Yoon, K, Medina-Gomez, C, Pitsillides, A, Hottenga, J J, Wood, A R, Ji, Y, Gao, Z, Haworth, S, Yousri, N A, Mitchell, R E, Chai, J F, Aadahl, M, Bjerregaard, A A, Yao, J, Manichaikul, A, Hwu, C M, Hung, Y J, Warren, H R, Ramirez, J, Bork-Jensen, J, Kårhus, L L, Goel, A, Sabater-Lleal, M, Noordam, R, Mauro, P, Matteo, F, McDaid, A F, Marques-Vidal, P, Wielscher, M, Trompet, S, Sattar, N, Møllehave, L T, Munz, M, Zeng, L, Huang, J, Yang, B, Poveda, A, Kurbasic, A, Lamina, C, Forer, L, Scholz, M, Galesloot, T E, Bradfield, J P, Ruotsalainen, S E, Daw, EW, Zmuda, J M, Mitchell, J S, Fuchsberger, C, Christensen, H, Brody, J A, Vazquez-Moreno, M, Feitosa, M F, Wojczynski, M K, Wang, Z, Preuss, M H, Mangino, M, Christofidou, P, Verweij, N, Benjamins, J W, Engmann, J, Tsao, N L, Verma, A, Slieker, R C, Lo, K S, Zilhao, N R, Le, P, Kleber, M E, Delgado, G E, Huo, S, Ikeda, D D, Iha, H, Yang, J, Liu, J, Demirkan, A, Leonard, H L, Marten, J, Frank, M, Schmidt, B, Smyth, L J, Cañadas-Garre, M, Wang, C, Nakatochi, M, Wong, A, Hutri-Kähönen, N, Sim, X, Xia, R, Huerta-Chagoya, A, Fernandez-Lopez, J C, Lyssenko, V, Nongmaithem, S S, Bayyana, S, Stringham, H M, Irvin, M R, Oldmeadow, C, Kim, H N, Ryu, S, Timmers, P R H J, Arbeeva, L, Dorajoo, R, Lange, L A, Prasad, G, Lorés-Motta, L, Pauper, M, Long, J, Li, X, Theusch, E, Takeuchi, F, Spracklen, C N, Loukola, A, Bollepalli, S, Warner, S C, Wang, Y X, Wei, W B, Nutile, T, Ruggiero, D, Sung, Y J, Chen, S, Liu, F, Yang, J, Kentistou, K A, Banas, B, Nardone, G G, Meidtner, K, Bielak, L F, Smith, J A, Hebbar, P, Farmaki, A E, Hofer, E, Lin, M, Concas, M P, Vaccargiu, S, van der Most, P J, Pitkänen, N, Cade, B E, van der Laan, S W, Chitrala, K N, Weiss, S, Bentley, A R, Doumatey, A P, Adeyemo, A A, Lee, J Y, Petersen, E R B, Nielsen, A A, Choi, H S, Nethander, M, Freitag-Wolf, S, Southam, L, Rayner, N W, Wang, C A, Lin, S Y, Wang, J S, Couture, C, Lyytikäinen, L P, Nikus, K, Cuellar-Partida, G, Vestergaard, H, Hidalgo, B, Giannakopoulou, O, Cai, Q, Obura, M O, van Setten, J, Li, X, Liang, J, Tang, H, Terzikhan, N, Shin, J H, Jackson, R D, Reiner, A P, Martin, L W, Chen, Z, Li, L, Kawaguchi, T, Thiery, J, Bis, J C, Launer, L J, Li, H, Nalls, M A, Raitakari, O T, Ichihara, S, Wild, S H, Nelson, C P, Campbell, H, Jäger, S, Nabika, T, Al-Mulla, F, Niinikoski, H, Braund, P S, Kolcic, I, Kovacs, P, Giardoglou, T, Katsuya, T, de Kleijn, D, de Borst, G J, Kim, E K, Adams, H H H, Ikram, M A, Zhu, X, Asselbergs, F W, Kraaijeveld, A O, Beulens, J W J, Shu, X O, Rallidis, L S, Pedersen, O, Hansen, T, Mitchell, P, Hewitt, A W, Kähönen, M, Pérusse, L, Bouchard, C, Tönjes, A, Chen, Y D I, Pennell, C E, Mori, T A, Lieb, W, Franke, A, Ohlsson, C, Mellström, D, Cho, Y S, Lee, H, Yuan, J M, Koh, W P, Rhee, S Y, Woo, J T, Heid, I M, Stark, K J, Zimmermann, M E, Völzke, H, Homuth, G, Evans, M K, Zonderman, A B, Polasek, O, Pasterkamp, G, Hoefer, I E, Redline, S, Pahkala, K, Oldehinkel, A J, Snieder, H, Biino, G, Schmidt, R, Schmidt, H, Bandinelli, S, Dedoussis, G, Thanaraj, T A, Kardia, S L R, Peyser, P A, Kato, N, Schulze, M B, Girotto, G, Böger, C A, Jung, B, Joshi, P K, Bennett, D A, De Jager, P L, Lu, X, Mamakou, V, Brown, M, Caulfield, M J, Munroe, P B, Guo, X, Ciullo, M, Jonas, J B, Samani, N J, Kaprio, J, Pajukanta, P, Tusié-Luna, T, Aguilar-Salinas, C A, Adair, L S, Bechayda, S A, de Silva, H J, Wickremasinghe, A R, Krauss, R M, Wu, J Y, Zheng, W, Hollander, A I, Bharadwaj, D, Correa, A, Wilson, J G, Lind, L, Heng, C K, Nelson, A E, Golightly, Y M, Wilson, J F, Penninx, B, Kim, H L, Attia, J, Scott, R J, Rao, D C, Arnett, D K, Hunt, S C, Walker, M, Koistinen, H A, Chandak, G R, Mercader, J M, Costanzo, M C, Jang, D, Burtt, N P, Villalpando, C G, Orozco, L, Fornage, M, Tai, ES, van Dam, R M, Lehtimäki, T, Chaturvedi, N, Yokota, M, Liu, J, Reilly, D F, McKnight, A J, Kee, F, Jöckel, K H, McCarthy, M I, Palmer, C N A, Vitart, V, Hayward, C, Simonsick, E, van Duijn, C M, Jin, Z B, Qu, J, Hishigaki, H, Lin, X, März, W, Gudnason, V, Tardif, J C, Lettre, G, Hart, L M T, Elders, P J M, Damrauer, S M, Kumari, M, Kivimaki, M, van der Harst, P, Spector, T D, Loos, R J F, Province, M A, Parra, E J, Cruz, M, Psaty, B M, Brandslund, I, Pramstaller, P P, Rotimi, C N, Christensen, K, Ripatti, S, Widén, E, Hakonarson, H, Grant, S F A, Kiemeney, L A L M, de Graaf, J, Loeffler, M, Kronenberg, F, Gu, D, Erdmann, J, Schunkert, H, Franks, P W, Linneberg, A, Jukema, J W, Khera, A V, Männikkö, M, Jarvelin, M R, Kutalik, Z, Francesco, C, Mook-Kanamori, D O, van Dijk, K W, Watkins, H, Strachan, D P, Grarup, N, Sever, P, Poulter, N, Chuang, L M, Rotter, J I, Dantoft, T M, Karpe, F, Neville, M J, Timpson, N J, Cheng, C Y, Wong, T Y, Khor, C C, Li, H, Sabanayagam, C, Peters, A, Gieger, C, Hattersley, A T, Pedersen, N L, Magnusson, P K E, Boomsma, D I, Willemsen, A H M, Cupples, LA, van Meurs, J B J, Ghanbari, M, Gordon-Larsen, P, Huang, W, Kim, Y J, Tabara, Y, Wareham, N J, Langenberg, C, Zeggini, E, Kuusisto, J, Laakso, M, Ingelsson, E, Abecasis, G, Chambers, J C, Kooner, J S, de Vries, P S, Morrison, A C, Hazelhurst, S, Ramsay, M, North, K E, Daviglus, M, Kraft, P, Martin, N G, Whitfield, J B, Abbas, S, Saleheen, D, Walters, R G, Holmes, M V, Black, C, Smith, B H, Baras, A, Justice, A E, Buring, J E, Ridker, P M, Chasman, D I, Kooperberg, C, Tamiya, G, Yamamoto, M, van Heel, D A, Trembath, R C, Wei, W Q, Jarvik, G P, Namjou, B, Hayes, M G, Ritchie, M D, Jousilahti, P, Salomaa, V, Hveem, K, Åsvold, B O, Kubo, M, Kamatani, Y, Okada, Y, Murakami, Y, Kim, B J, Thorsteinsdottir, U, Stefansson, K, Zhang, J, Chen, YE, Ho, Y L, Lynch, J A, Rader, D J, Tsao, P S, Chang, K M, Cho, K, O'Donnell, C J, Gaziano, J M, Wilson, P W F, Frayling, T M, Hirschhorn, J N, Kathiresan, S, Mohlke, K L, Sun, Y V, Morris, A P, Boehnke, M, Brown, C D, Natarajan, P, Deloukas, P, Willer, C J, Assimes, T L & Peloso, G M 2022, ' Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ', Genome Biology, vol. 23, no. 1, 268 . https://doi.org/10.1186/s13059-022-02837-1
Genome Biology, 23, 1
Genome Biology, 23(1). BMC
Genome Biology, 23(1):268. BioMed Central Ltd.
Kanoni, S, Graham, S E, Wang, Y, Hottenga, J J, Penninx, B, Boomsma, D I, Willemsen, G, Willer, C J, Assimes, T L, Peloso, G M & Global Lipids Genetics Consortium 2022, ' Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ', Genome Biology, vol. 23, no. 1, 268 . https://doi.org/10.1186/s13059-022-02837-1
Genome Biology
Genome Biology, 23
Kanoni, S, Graham, S E, Wang, Y, Surakka, I, Ramdas, S, Zhu, X, Clarke, S L, Bhatti, K F, Vedantam, S, Winkler, T W, Locke, A E, Marouli, E, Zajac, G J M, Wu, K-H H, Ntalla, I, Hui, Q, Klarin, D, Hilliard, A T, Wang, Z, Xue, C, Thorleifsson, G, Helgadottir, A, Gudbjartsson, D F, Holm, H, Olafsson, I, Hwang, M Y, Han, S, Akiyama, M, Sakaue, S, Terao, C, Kanai, M, Zhou, W, Brumpton, B M, Rasheed, H, Havulinna, A S, Veturi, Y, Pacheco, J A, Rosenthal, E A, Lingren, T, Feng, Q, Kullo, I J, Narita, A, Takayama, J, Martin, H C, Hunt, K A, Trivedi, B, Haessler, J, Giulianini, F, Bradford, Y, Miller, J E, Campbell, A, Lin, K, Millwood, I Y, Rasheed, A, Hindy, G, Faul, J D, Zhao, W, Weir, D R, Turman, C, Huang, H, Graff, M, Choudhury, A, Sengupta, D, Mahajan, A, Brown, M R, Zhang, W, Yu, K, Schmidt, E M, Pandit, A, Gustafsson, S, Yin, X, Luan, J, Zhao, J-H, Matsuda, F, Jang, H-M, Yoon, K, Medina-Gomez, C, Pitsillides, A, Hottenga, J J, Wood, A R, Ji, Y, Gao, Z, Haworth, S, Yousri, N A, Mitchell, R E, Chai, J F, Aadahl, M, Bjerregaard, A A, Yao, J, Manichaikul, A, Hwu, C-M, Hung, Y-J, Warren, H R, Ramirez, J, Bork-Jensen, J, Kårhus, L L, Goel, A, Sabater-Lleal, M, Noordam, R, Mauro, P, Matteo, F, McDaid, A F, Marques-Vidal, P, Wielscher, M, Trompet, S, Sattar, N, Møllehave, L T, Munz, M, Zeng, L, Huang, J, Yang, B, Poveda, A, Kurbasic, A, Lamina, C, Forer, L, Scholz, M, Galesloot, T E, Bradfield, J P, Ruotsalainen, S E, Daw, E W, Zmuda, J M, Mitchell, J S, Fuchsberger, C, Christensen, H, Brody, J A, Vazquez-Moreno, M, Feitosa, M F, Wojczynski, M K, Wang, Z, Preuss, M H, Mangino, M, Christofidou, P, Verweij, N, Benjamins, J W, Engmann, J, Tsao, N L, Verma, A, Slieker, R C, Lo, K S, Zilhao, N R, le, P, Kleber, M E, Delgado, G E, Huo, S, Ikeda, D D, Iha, H, Yang, J, Liu, J, Demirkan, A, Leonard, H L, Marten, J, Frank, M, Schmidt, B R, Smyth, L J, Cañadas-Garre, M, Wang, C, Nakatochi, M, Wong, A, Hutri-Kähönen, N, Sim, X, Xia, R, Huerta-Chagoya, A, Fernandez-Lopez, J C, Lyssenko, V, Nongmaithem, S S, Bayyana, S, Stringham, H M, Irvin, M R, Oldmeadow, C, Kim, H-N, Ryu, S, Timmers, P R H J, Arbeeva, L, Dorajoo, R, Lange, L A, Prasad, G, Lorés-Motta, L, Pauper, M, Long, J, Li, X, Theusch, E, Takeuchi, F, Spracklen, C N, Loukola, A, Bollepalli, S, Warner, S C, Wang, Y X, Wei, W B, Nutile, T, Ruggiero, D, Sung, Y J, Chen, S, Liu, F, Yang, J, Kentistou, K A, Banas, B, Nardone, G G, Meidtner, K, Bielak, L F, Smith, J A, Hebbar, P, Farmaki, A-E, Hofer, E, Lin, M, Concas, M P, Vaccargiu, S, van der Most, P J, Pitkänen, N, Cade, B E, van der Laan, S W, Chitrala, K N, Weiss, S, Bentley, A R, Doumatey, A P, Adeyemo, A A, Lee, J Y, Petersen, E R B, Nielsen, A A, Choi, H S, Nethander, M, Freitag-Wolf, S, Southam, L, Rayner, N W, Wang, C A, Lin, S-Y, Wang, J-S, Couture, C, Lyytikäinen, L-P, Nikus, K, Cuellar-Partida, G, Vestergaard, H, Hidalgo, B, Giannakopoulou, O, Cai, Q, Obura, M O, van Setten, J, Li, X, Liang, J, Tang, H, Terzikhan, N, Shin, J H, Jackson, R D, 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Genome Biol. 23:268 (2022)
Genome Biology, 23:268. BMC
Genome biology, vol. 23, no. 1, pp. 268
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Lyssenko, V, Nongmaithem, S S, Bayyana, S, Stringham, H M, Irvin, M R, Oldmeadow, C, Kim, H-N, Ryu, S, Timmers, P R H J, Arbeeva, L, Dorajoo, R, Lange, L A, Prasad, G, Lorés-Motta, L, Pauper, M, Long, J, Li, X, Theusch, E, Takeuchi, F, Spracklen, C N, Loukola, A, Bollepalli, S, Warner, S C, Wang, Y X, Wei, W B, Nutile, T, Ruggiero, D, Sung, Y J, Chen, S, Liu, F, Yang, J, Kentistou, K A, Banas, B, Nardone, G G, Meidtner, K, Bielak, L F, Smith, J A, Hebbar, P, Farmaki, A-E, Hofer, E, Lin, M, Concas, M P, Vaccargiu, S, van der Most, P J, Pitkänen, N, Cade, B E, van der Laan, S W, Chitrala, K N, Weiss, S, Bentley, A R, Doumatey, A P, Adeyemo, A A, Lee, J Y, Petersen, E R B, Nielsen, A A, Choi, H S, Nethander, M, Freitag-Wolf, S, Southam, L, Rayner, N W, Wang, C A, Lin, S-Y, Wang, J-S, Couture, C, Lyytikäinen, L-P, Nikus, K, Cuellar-Partida, G, Vestergaard, H, Hidalgo, B, Giannakopoulou, O, Cai, Q, Obura, M O, van Setten, J, Li, X, Liang, J, Tang, H, Terzikhan, N, Shin, J H, Jackson, R D, Reiner, A P, Martin, L W, Chen, Z, Li, L, Kawaguchi, T, Thiery, J, Bis, J C, Launer, L J, Li, H, Nalls, M A, Raitakari, O T, Ichihara, S, Wild, S H, Nelson, C P, Campbell, H, Jäger, S, Nabika, T, Al-Mulla, F, Niinikoski, H, Braund, P S, Kolcic, I, Kovacs, P, Giardoglou, T, Katsuya, T, de Kleijn, D, de Borst, G J, Kim, E K, Adams, H H H, Ikram, M A, Zhu, X, Asselbergs, F W, Kraaijeveld, A O, Beulens, J W J, Shu, X-O, Rallidis, L S, Pedersen, O, Hansen, T, Mitchell, P, Hewitt, A W, Kähönen, M, Pérusse, L, Bouchard, C, Tönjes, A, Chen, Y-D I, Pennell, C E, Mori, T A, Lieb, W, Franke, A, Ohlsson, C, Mellström, D, Cho, Y S, Lee, H, Yuan, J-M, Koh, W-P, Rhee, S Y, Woo, J-T, Heid, I M, Stark, K J, Zimmermann, M E, Völzke, H, Homuth, G, Evans, M K, Zonderman, A B, Polasek, O, Pasterkamp, G, Hoefer, I E, Redline, S, Pahkala, K, Oldehinkel, A J, Snieder, H, Biino, G, Schmidt, R, Schmidt, H, Bandinelli, S, Dedoussis, G, Thanaraj, T A, Kardia, S L R, Peyser, P A, Kato, N, Schulze, M B, Girotto, G, Böger, C A, Jung, B, Joshi, P K, Bennett, D A, De Jager, P L, Lu, X, Mamakou, V, Brown, M, Caulfield, M J, Munroe, P B, Guo, X, Ciullo, M, Jonas, J B, Samani, N J, Kaprio, J, Pajukanta, P, Tusié-Luna, T, Aguilar-Salinas, C A, Adair, L S, Bechayda, S A, de Silva, H J, Wickremasinghe, A R, Krauss, R M, Wu, J-Y, Zheng, W, Hollander, A I, Bharadwaj, D, Correa, A, Wilson, J G, Lind, L, Heng, C-K, Nelson, A E, Golightly, Y M, Wilson, J F, Penninx, B, Kim, H-L, Attia, J, Scott, R J, Rao, D C, Arnett, D K, Hunt, S C, Walker, M, Koistinen, H A, Chandak, G R, Mercader, J M, Costanzo, M C, Jang, D, Burtt, N P, Villalpando, C G, Orozco, L, Fornage, M, Tai, ES, van Dam, R M, Lehtimäki, T, Chaturvedi, N, Yokota, M, Liu, J, Reilly, D F, McKnight, A J, Kee, F, Jöckel, K-H, McCarthy, M I, Palmer, C N A, Vitart, V, Hayward, C, Simonsick, E, van Duijn, C M, Jin, Z-B, Qu, J, Hishigaki, H, Lin, X, März, W, Gudnason, V, Tardif, J-C, Lettre, G, Hart, L M, Elders, P J M, Damrauer, S M, Kumari, M, Kivimaki, M, van der Harst, P, Spector, T D, Loos, R J F, Province, M A, Parra, E J, Cruz, M, Psaty, B M, Brandslund, I, Pramstaller, P P, Rotimi, C N, Christensen, K, Ripatti, S, Widén, E, Hakonarson, H, Grant, S F A, Kiemeney, L A L M, de Graaf, J, Loeffler, M, Kronenberg, F, Gu, D, Erdmann, J, Schunkert, H, Franks, P W, Linneberg, A, Jukema, J W, Khera, A V, Männikkö, M, Jarvelin, M-R, Kutalik, Z, Francesco, C, Mook-Kanamori, D O, van Dijk, K W, Watkins, H, Strachan, D P, Grarup, N, Sever, P, Poulter, N, Chuang, L-M, Rotter, J I, Dantoft, T M, Karpe, F, Neville, M J, Timpson, N J, Cheng, C-Y, Wong, T-Y, Khor, C C, Li, H, Sabanayagam, C, Peters, A, Gieger, C, Hattersley, A T, Pedersen, N L, Magnusson, P K E, Boomsma, D I, Willemsen, A H M, Cupples, LA, van Meurs, J B J, Ghanbari, M, Gordon-Larsen, P, Huang, W, Kim, Y J, Tabara, Y, Wareham, N J, Langenberg, C, Zeggini, E, Kuusisto, J, Laakso, M, Ingelsson, E, Abecasis, G, Chambers, J C, Kooner, J S, de Vries, P S, Morrison, A C, Hazelhurst, S, Ramsay, M, North, K E, Daviglus, M, Kraft, P, Martin, N G, Whitfield, J B, Abbas, S, Saleheen, D, Walters, R G, Holmes, M V, Black, C, Smith, B H, Baras, A, Justice, A E, Buring, J E, Ridker, P M, Chasman, D I, Kooperberg, C, Tamiya, G, Yamamoto, M, van Heel, D A, Trembath, R C, Wei, W-Q, Jarvik, G P, Namjou, B, Hayes, M G, Ritchie, M D, Jousilahti, P, Salomaa, V, Hveem, K, Åsvold, B O, Kubo, M, Kamatani, Y, Okada, Y, Murakami, Y, Kim, B-J, Thorsteinsdottir, U, Stefansson, K, Zhang, J, Chen, YE, Ho, Y-L, Lynch, J A, Rader, D J, Tsao, P S, Chang, K-M, Cho, K, O'Donnell, C J, Gaziano, J M, Wilson, P W F, Frayling, T M, Hirschhorn, J N, Kathiresan, S, Mohlke, K L, Sun, Y V, Morris, A P, Boehnke, M, Natarajan, P, Deloukas, P, Willer, C J, Assimes, T L & Peloso, G M 2022, ' Implicating genes, pleiotropy and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ', Genome biology, vol. 23, no. 1, 268 . https://doi.org/10.1186/s13059-022-02837-1
Kanoni, S, Graham, S E, Wang, Y, Surakka, I, Ramdas, S, Zhu, X, Clarke, S L, Bhatti, K F, Vedantam, S, Winkler, T W, Locke, A E, Marouli, E, Zajac, G J M, Wu, K H H, Ntalla, I, Hui, Q, Klarin, D, Hilliard, A T, Wang, Z, Xue, C, Thorleifsson, G, Helgadottir, A, Gudbjartsson, D F, Holm, H, Olafsson, I, Hwang, M Y, Han, S, Akiyama, M, Sakaue, S, Terao, C, Kanai, M, Zhou, W, Brumpton, B M, Rasheed, H, Havulinna, A S, Veturi, Y, Pacheco, J A, Rosenthal, E A, Lingren, T, Feng, Q P, Kullo, I J, Narita, A, Takayama, J, Martin, H C, Hunt, K A, Trivedi, B, Haessler, J, Giulianini, F, Bradford, Y, Miller, J E, Campbell, A, Lin, K, Millwood, I Y, Rasheed, A, Hindy, G, Faul, J D, Zhao, W, Weir, D R, Turman, C, Huang, H, Graff, M, Choudhury, A, Sengupta, D, Mahajan, A, Brown, M R, Zhang, W, Yu, K, Schmidt, E M, Pandit, A, Gustafsson, S, Yin, X, Luan, J, Zhao, J H, Matsuda, F, Jang, H M, Yoon, K, Medina-Gomez, C, Pitsillides, A, Hottenga, J J, Wood, A R, Ji, Y, Gao, Z, Haworth, S, Yousri, N A, Mitchell, R E, Chai, J F, Aadahl, M, Bjerregaard, A A, Yao, J, Manichaikul, A, Hwu, C M, Hung, Y J, Warren, H R, Ramirez, J, Bork-Jensen, J, Kårhus, L L, Goel, A, Sabater-Lleal, M, Noordam, R, Mauro, P, Matteo, F, McDaid, A F, Marques-Vidal, P, Wielscher, M, Trompet, S, Sattar, N, Møllehave, L T, Munz, M, Zeng, L, Huang, J, Yang, B, Poveda, A, Kurbasic, A, Lamina, C, Forer, L, Scholz, M, Galesloot, T E, Bradfield, J P, Ruotsalainen, S E, Daw, EW, Zmuda, J M, Mitchell, J S, Fuchsberger, C, Christensen, H, Brody, J A, Vazquez-Moreno, M, Feitosa, M F, Wojczynski, M K, Wang, Z, Preuss, M H, Mangino, M, Christofidou, P, Verweij, N, Benjamins, J W, Engmann, J, Tsao, N L, Verma, A, Slieker, R C, Lo, K S, Zilhao, N R, Le, P, Kleber, M E, Delgado, G E, Huo, S, Ikeda, D D, Iha, H, Yang, J, Liu, J, Demirkan, A, Leonard, H L, Marten, J, Frank, M, Schmidt, B, Smyth, L J, Cañadas-Garre, M, Wang, C, Nakatochi, M, Wong, A, Hutri-Kähönen, N, Sim, X, Xia, R, Huerta-Chagoya, A, Fernandez-Lopez, J C, Lyssenko, V, Nongmaithem, S S, Bayyana, S, Stringham, H M, Irvin, M R, Oldmeadow, C, Kim, H N, Ryu, S, Timmers, P R H J, Arbeeva, L, Dorajoo, R, Lange, L A, Prasad, G, Lorés-Motta, L, Pauper, M, Long, J, Li, X, Theusch, E, Takeuchi, F, Spracklen, C N, Loukola, A, Bollepalli, S, Warner, S C, Wang, Y X, Wei, W B, Nutile, T, Ruggiero, D, Sung, Y J, Chen, S, Liu, F, Yang, J, Kentistou, K A, Banas, B, Nardone, G G, Meidtner, K, Bielak, L F, Smith, J A, Hebbar, P, Farmaki, A E, Hofer, E, Lin, M, Concas, M P, Vaccargiu, S, van der Most, P J, Pitkänen, N, Cade, B E, van der Laan, S W, Chitrala, K N, Weiss, S, Bentley, A R, Doumatey, A P, Adeyemo, A A, Lee, J Y, Petersen, E R B, Nielsen, A A, Choi, H S, Nethander, M, Freitag-Wolf, S, Southam, L, Rayner, N W, Wang, C A, Lin, S Y, Wang, J S, Couture, C, Lyytikäinen, L P, Nikus, K, Cuellar-Partida, G, Vestergaard, H, Hidalgo, B, Giannakopoulou, O, Cai, Q, Obura, M O, van Setten, J, Li, X, Liang, J, Tang, H, Terzikhan, N, Shin, J H, Jackson, R D, Reiner, A P, Martin, L W, Chen, Z, Li, L, Kawaguchi, T, Thiery, J, Bis, J C, Launer, L J, Li, H, Nalls, M A, Raitakari, O T, Ichihara, S, Wild, S H, Nelson, C P, Campbell, H, Jäger, S, Nabika, T, Al-Mulla, F, Niinikoski, H, Braund, P S, Kolcic, I, Kovacs, P, Giardoglou, T, Katsuya, T, de Kleijn, D, de Borst, G J, Kim, E K, Adams, H H H, Ikram, M A, Zhu, X, Asselbergs, F W, Kraaijeveld, A O, Beulens, J W J, Shu, X O, Rallidis, L S, Pedersen, O, Hansen, T, Mitchell, P, Hewitt, A W, Kähönen, M, Pérusse, L, Bouchard, C, Tönjes, A, Chen, Y D I, Pennell, C E, Mori, T A, Lieb, W, Franke, A, Ohlsson, C, Mellström, D, Cho, Y S, Lee, H, Yuan, J M, Koh, W P, Rhee, S Y, Woo, J T, Heid, I M, Stark, K J, Zimmermann, M E, Völzke, H, Homuth, G, Evans, M K, Zonderman, A B, Polasek, O, Pasterkamp, G, Hoefer, I E, Redline, S, Pahkala, K, Oldehinkel, A J, Snieder, H, Biino, G, Schmidt, R, Schmidt, H, Bandinelli, S, Dedoussis, G, Thanaraj, T A, Kardia, S L R, Peyser, P A, Kato, N, Schulze, M B, Girotto, G, Böger, C A, Jung, B, Joshi, P K, Bennett, D A, De Jager, P L, Lu, X, Mamakou, V, Brown, M, Caulfield, M J, Munroe, P B, Guo, X, Ciullo, M, Jonas, J B, Samani, N J, Kaprio, J, Pajukanta, P, Tusié-Luna, T, Aguilar-Salinas, C A, Adair, L S, Bechayda, S A, de Silva, H J, Wickremasinghe, A R, Krauss, R M, Wu, J Y, Zheng, W, Hollander, A I, Bharadwaj, D, Correa, A, Wilson, J G, Lind, L, Heng, C K, Nelson, A E, Golightly, Y M, Wilson, J F, Penninx, B, Kim, H L, Attia, J, Scott, R J, Rao, D C, Arnett, D K, Hunt, S C, Walker, M, Koistinen, H A, Chandak, G R, Mercader, J M, Costanzo, M C, Jang, D, Burtt, N P, Villalpando, C G, Orozco, L, Fornage, M, Tai, ES, van Dam, R M, Lehtimäki, T, Chaturvedi, N, Yokota, M, Liu, J, Reilly, D F, McKnight, A J, Kee, F, Jöckel, K H, McCarthy, M I, Palmer, C N A, Vitart, V, Hayward, C, Simonsick, E, van Duijn, C M, Jin, Z B, Qu, J, Hishigaki, H, Lin, X, März, W, Gudnason, V, Tardif, J C, Lettre, G, Hart, L M T, Elders, P J M, Damrauer, S M, Kumari, M, Kivimaki, M, van der Harst, P, Spector, T D, Loos, R J F, Province, M A, Parra, E J, Cruz, M, Psaty, B M, Brandslund, I, Pramstaller, P P, Rotimi, C N, Christensen, K, Ripatti, S, Widén, E, Hakonarson, H, Grant, S F A, Kiemeney, L A L M, de Graaf, J, Loeffler, M, Kronenberg, F, Gu, D, Erdmann, J, Schunkert, H, Franks, P W, Linneberg, A, Jukema, J W, Khera, A V, Männikkö, M, Jarvelin, M R, Kutalik, Z, Francesco, C, Mook-Kanamori, D O, van Dijk, K W, Watkins, H, Strachan, D P, Grarup, N, Sever, P, Poulter, N, Chuang, L M, Rotter, J I, Dantoft, T M, Karpe, F, Neville, M J, Timpson, N J, Cheng, C Y, Wong, T Y, Khor, C C, Li, H, Sabanayagam, C, Peters, A, Gieger, C, Hattersley, A T, Pedersen, N L, Magnusson, P K E, Boomsma, D I, Willemsen, A H M, Cupples, LA, van Meurs, J B J, Ghanbari, M, Gordon-Larsen, P, Huang, W, Kim, Y J, Tabara, Y, Wareham, N J, Langenberg, C, Zeggini, E, Kuusisto, J, Laakso, M, Ingelsson, E, Abecasis, G, Chambers, J C, Kooner, J S, de Vries, P S, Morrison, A C, Hazelhurst, S, Ramsay, M, North, K E, Daviglus, M, Kraft, P, Martin, N G, Whitfield, J B, Abbas, S, Saleheen, D, Walters, R G, Holmes, M V, Black, C, Smith, B H, Baras, A, Justice, A E, Buring, J E, Ridker, P M, Chasman, D I, Kooperberg, C, Tamiya, G, Yamamoto, M, van Heel, D A, Trembath, R C, Wei, W Q, Jarvik, G P, Namjou, B, Hayes, M G, Ritchie, M D, Jousilahti, P, Salomaa, V, Hveem, K, Åsvold, B O, Kubo, M, Kamatani, Y, Okada, Y, Murakami, Y, Kim, B J, Thorsteinsdottir, U, Stefansson, K, Zhang, J, Chen, YE, Ho, Y L, Lynch, J A, Rader, D J, Tsao, P S, Chang, K M, Cho, K, O'Donnell, C J, Gaziano, J M, Wilson, P W F, Frayling, T M, Hirschhorn, J N, Kathiresan, S, Mohlke, K L, Sun, Y V, Morris, A P, Boehnke, M, Brown, C D, Natarajan, P, Deloukas, P, Willer, C J, Assimes, T L & Peloso, G M 2022, ' Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ', Genome Biology, vol. 23, no. 1, 268 . https://doi.org/10.1186/s13059-022-02837-1
Genome Biology, 23, 1
Genome Biology, 23(1). BMC
Genome Biology, 23(1):268. BioMed Central Ltd.
Kanoni, S, Graham, S E, Wang, Y, Hottenga, J J, Penninx, B, Boomsma, D I, Willemsen, G, Willer, C J, Assimes, T L, Peloso, G M & Global Lipids Genetics Consortium 2022, ' Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ', Genome Biology, vol. 23, no. 1, 268 . https://doi.org/10.1186/s13059-022-02837-1
Genome Biology
Genome Biology, 23
Kanoni, S, Graham, S E, Wang, Y, Surakka, I, Ramdas, S, Zhu, X, Clarke, S L, Bhatti, K F, Vedantam, S, Winkler, T W, Locke, A E, Marouli, E, Zajac, G J M, Wu, K-H H, Ntalla, I, Hui, Q, Klarin, D, Hilliard, A T, Wang, Z, Xue, C, Thorleifsson, G, Helgadottir, A, Gudbjartsson, D F, Holm, H, Olafsson, I, Hwang, M Y, Han, S, Akiyama, M, Sakaue, S, Terao, C, Kanai, M, Zhou, W, Brumpton, B M, Rasheed, H, Havulinna, A S, Veturi, Y, Pacheco, J A, Rosenthal, E A, Lingren, T, Feng, Q, Kullo, I J, Narita, A, Takayama, J, Martin, H C, Hunt, K A, Trivedi, B, Haessler, J, Giulianini, F, Bradford, Y, Miller, J E, Campbell, A, Lin, K, Millwood, I Y, Rasheed, A, Hindy, G, Faul, J D, Zhao, W, Weir, D R, Turman, C, Huang, H, Graff, M, Choudhury, A, Sengupta, D, Mahajan, A, Brown, M R, Zhang, W, Yu, K, Schmidt, E M, Pandit, A, Gustafsson, S, Yin, X, Luan, J, Zhao, J-H, Matsuda, F, Jang, H-M, Yoon, K, Medina-Gomez, C, Pitsillides, A, Hottenga, J J, Wood, A R, Ji, Y, Gao, Z, Haworth, S, Yousri, N A, Mitchell, R E, Chai, J F, Aadahl, M, Bjerregaard, A A, Yao, J, Manichaikul, A, Hwu, C-M, Hung, Y-J, Warren, H R, Ramirez, J, Bork-Jensen, J, Kårhus, L L, Goel, A, Sabater-Lleal, M, Noordam, R, Mauro, P, Matteo, F, McDaid, A F, Marques-Vidal, P, Wielscher, M, Trompet, S, Sattar, N, Møllehave, L T, Munz, M, Zeng, L, Huang, J, Yang, B, Poveda, A, Kurbasic, A, Lamina, C, Forer, L, Scholz, M, Galesloot, T E, Bradfield, J P, Ruotsalainen, S E, Daw, E W, Zmuda, J M, Mitchell, J S, Fuchsberger, C, Christensen, H, Brody, J A, Vazquez-Moreno, M, Feitosa, M F, Wojczynski, M K, Wang, Z, Preuss, M H, Mangino, M, Christofidou, P, Verweij, N, Benjamins, J W, Engmann, J, Tsao, N L, Verma, A, Slieker, R C, Lo, K S, Zilhao, N R, le, P, Kleber, M E, Delgado, G E, Huo, S, Ikeda, D D, Iha, H, Yang, J, Liu, J, Demirkan, A, Leonard, H L, Marten, J, Frank, M, Schmidt, B R, Smyth, L J, Cañadas-Garre, M, Wang, C, Nakatochi, M, Wong, A, Hutri-Kähönen, N, Sim, X, Xia, R, Huerta-Chagoya, A, Fernandez-Lopez, J C, Lyssenko, V, Nongmaithem, S S, Bayyana, S, Stringham, H M, Irvin, M R, Oldmeadow, C, Kim, H-N, Ryu, S, Timmers, P R H J, Arbeeva, L, Dorajoo, R, Lange, L A, Prasad, G, Lorés-Motta, L, Pauper, M, Long, J, Li, X, Theusch, E, Takeuchi, F, Spracklen, C N, Loukola, A, Bollepalli, S, Warner, S C, Wang, Y X, Wei, W B, Nutile, T, Ruggiero, D, Sung, Y J, Chen, S, Liu, F, Yang, J, Kentistou, K A, Banas, B, Nardone, G G, Meidtner, K, Bielak, L F, Smith, J A, Hebbar, P, Farmaki, A-E, Hofer, E, Lin, M, Concas, M P, Vaccargiu, S, van der Most, P J, Pitkänen, N, Cade, B E, van der Laan, S W, Chitrala, K N, Weiss, S, Bentley, A R, Doumatey, A P, Adeyemo, A A, Lee, J Y, Petersen, E R B, Nielsen, A A, Choi, H S, Nethander, M, Freitag-Wolf, S, Southam, L, Rayner, N W, Wang, C A, Lin, S-Y, Wang, J-S, Couture, C, Lyytikäinen, L-P, Nikus, K, Cuellar-Partida, G, Vestergaard, H, Hidalgo, B, Giannakopoulou, O, Cai, Q, Obura, M O, van Setten, J, Li, X, Liang, J, Tang, H, Terzikhan, N, Shin, J H, Jackson, R D, Reiner, A P, Martin, L W, Chen, Z, Li, L, Kawaguchi, T, Thiery, J, Bis, J C, Launer, L J, Li, H, Nalls, M A, Raitakari, O T, Ichihara, S, Wild, S H, Nelson, C P, Campbell, H, Jäger, S, Nabika, T, Al-Mulla, F, Niinikoski, H, Braund, P S, Kolcic, I, Kovacs, P, Giardoglou, T, Katsuya, T, de Kleijn, D, de Borst, G J, Kim, E K, Adams, H H H, Ikram, M A, Zhu, X, Asselbergs, F W, Kraaijeveld, A O, Beulens, J W J, Shu, X-O, Rallidis, L S, Pedersen, O, Hansen, T, Mitchell, P, Hewitt, A W, Kähönen, M, Pérusse, L, Bouchard, C, Tönjes, A, Chen, Y-D I, Pennell, C E, Mori, T A, Lieb, W, Franke, A, Ohlsson, C, Mellström, D, Cho, Y S, Lee, H, Yuan, J-M, Koh, W-P, Rhee, S Y, Woo, J-T, Heid, I M, Stark, K J, Zimmermann, M E, Völzke, H, Homuth, G, Evans, M K, Zonderman, A B, Polasek, O, Pasterkamp, G, Hoefer, I E, Redline, S, Pahkala, K, Oldehinkel, A J, Snieder, H, Biino, G, Schmidt, R, Schmidt, H, Bandinelli, S, Dedoussis, G, Thanaraj, T A, Kardia, S L R, Peyser, P A, Kato, N, Schulze, M B, Girotto, G, Böger, C A, Jung, B, Joshi, P K, Bennett, D A, de Jager, P L, Lu, X, Mamakou, V, Brown, M, Caulfield, M J, Munroe, P B, Guo, X, Ciullo, M, Jonas, J B, Samani, N J, Kaprio, J, Pajukanta, P I, Tusié-Luna, T, Aguilar-Salinas, C A, Adair, L S, Bechayda, S A, de Silva, H J, Wickremasinghe, A R, Krauss, R M, Wu, J-Y, Zheng, W, Hollander, A I, Bharadwaj, D, Correa, A, Wilson, J G, Lind, L, Heng, C-K, Nelson, A E, Golightly, Y M, Wilson, J F, Penninx, B, Kim, H-L, Attia, J, Scott, R J, Rao, D C, Arnett, D K, Hunt, S C, Walker, M, Koistinen, H A, Chandak, G R, Mercader, J M, Costanzo, M C, Jang, D, Burtt, N P, Villalpando, C G, Orozco, L, Fornage, M, Tai, E S, van Dam, R M, Lehtimäki, T, Chaturvedi, N, Yokota, M, Liu, J, Reilly, D F, McKnight, A J, Kee, F, Jöckel, K-H, McCarthy, M I, Palmer, C N A, Vitart, V, Hayward, C, Simonsick, E, van Duijn, C M, Jin, Z-B, Qu, J, Hishigaki, H, Lin, X, März, W, Gudnason, V, Tardif, J-C, Lettre, G, Hart, L M, Elders, P J M, Damrauer, S M, Kumari, M, Kivimaki, M, van der Harst, P, Spector, T D, Loos, R J F, Province, M A, Parra, E J, Cruz, M, Psaty, B M, Brandslund, I, Pramstaller, P P, Rotimi, C N, Christensen, K, Ripatti, S, Widén, E, Hakonarson, H, Grant, S F A, Kiemeney, L A L M, de Graaf, J, Loeffler, M, Kronenberg, F, Gu, D, Erdmann, J, Schunkert, H, Franks, P W, Linneberg, A, Jukema, J W, Khera, A V, Männikkö, M, Jarvelin, M-R, Kutalik, Z, Francesco, C, Mook-Kanamori, D O, van Dijk, K W, Watkins, H, Strachan, D P, Grarup, N, Sever, P, Poulter, N, Chuang, L-M, Rotter, J I, Dantoft, T M, Karpe, F, Neville, M J, Timpson, N J, Cheng, C-Y, Wong, T-Y, Khor, C C, Li, H, Sabanayagam, C, Peters, A, Gieger, C, Hattersley, A T, Pedersen, N L, Magnusson, P K E, Boomsma, D I, Willemsen, A H M, Cupples, L A, van Meurs, J B J, Ghanbari, M, Gordon-Larsen, P, Huang, W, Kim, Y J, Tabara, Y, Wareham, N J, Langenberg, C, Zeggini, E, Kuusisto, J, Laakso, M, Ingelsson, E, Abecasis, G, Chambers, J C, Kooner, J S, de Vries, P S, Morrison, A C, Hazelhurst, S, Ramsay, M, North, K E, Daviglus, M, Kraft, P, Martin, N G, Whitfield, J B, Abbas, S, Saleheen, D, Walters, R G, Holmes, M V, Black, C, Smith, B H, Baras, A, Justice, A E, Buring, J E, Ridker, P M, Chasman, D I, Kooperberg, C, Tamiya, G, Yamamoto, M, van Heel, D A, Trembath, R C, Wei, W-Q, Jarvik, G P, Namjou, B, Hayes, M G, Ritchie, M D, Jousilahti, P, Salomaa, V, Hveem, K, Åsvold, B O, Kubo, M, Kamatani, Y, Okada, Y, Murakami, Y, Kim, B-J, Thorsteinsdottir, U, Stefansson, K, Zhang, J, Chen, Y E, Ho, Y-L, Lynch, J A, Rader, D J, Tsao, P S, Chang, K-M, Cho, K, O’Donnell, C J, Gaziano, J M, Wilson, P W F, Frayling, T M, Hirschhorn, J N, Kathiresan, S, Mohlke, K L, Sun, Y V, Morris, A P, Boehnke, M, Brown, C D, Natarajan, P, Deloukas, P, Willer, C J, Assimes, T L & Peloso, G M 2022, ' Implicating genes, pleiotropy, and sexual dimorphism at blood lipid loci through multi-ancestry meta-analysis ', Genome Biology, vol. 23, no. 1, 268 . https://doi.org/10.1186/s13059-022-02837-1
Genome Biol. 23:268 (2022)
Background: Genetic variants within nearly 1000 loci are known to contribute to modulation of blood lipid levels. However, the biological pathways underlying these associations are frequently unknown, limiting understanding of these findings and hind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cea2b9dfd52b0ec731c7927b5bf8400b
https://research.vu.nl/en/publications/9ce639f6-4d7e-4365-a087-bce0a6721e09
https://research.vu.nl/en/publications/9ce639f6-4d7e-4365-a087-bce0a6721e09
Autor:
Martina Müller-Nurasyid, Jerome I. Rotter, David M. Evans, John P. Kemp, Emelia J. Benjamin, Graciela E. Delgado, Vilmundur Gudnason, Ann Hammarstedt, Panos Deloukas, Aroon D. Hingorani, Riccardo E. Marioni, David Stacey, Jenny van Dongen, Eric Boerwinkle, Joachim Heinrich, Yongmei Liu, S. Goya Wannamethee, Delilah Zabaneh, Braxton D. Mitchell, Marie Standl, Jackie F. Price, Maria G. Stathopoulou, Yoav Ben-Shlomo, Joris Deelen, Eero Kajantie, Mohammadreza Abdollahi, Christie M. Ballantyne, Johan G. Eriksson, Ilkka Seppälä, Elnaz Naderi, Barbara J. Jefferis, Richard W Morris, Nicholas J. Timpson, George Dedoussis, Sirpa Jalkanen, Mika Kivimäki, Perminder S. Sachdev, Diana van Heemst, Melanie Waldenberger, Gaurav Singhal, Elisabeth Thiering, Olli T. Raitakari, Anders Hamsten, Zoltán Kutalik, L. Bain, Eco J. C. de Geus, Tarunveer S. Ahluwalia, Yuri Milaneschi, Hubert Scharnagl, Juan P. Casas, Georg Homuth, Claes Ohlsson, Abbas Dehghan, Nicola J. Armstrong, Behrooz Z. Alizadeh, Terho Lehtimäki, Steve E. Humphries, Naveed Sattar, Bram P. Prins, Peter Rossing, Sophie Visvikis-Siest, Joana A. Revez, Ilja M. Nolte, Stella Trompet, Harold Snieder, Marian Beekman, Diana Marek, Beate St Pourcain, Thorkild I. A. Sørensen, Silvia Naitza, Karen A. Mather, Uwe Völker, Eline Slagboom, Tina Shah, Magdalene C. Jawahar, Jens Baumert, Alexander Teumer, Dorret I. Boomsma, Marcus E. Kleber, Peter Vollenweider, Wolfgang Koenig, Brenda W.J.H. Penninx, Kenneth Rice, Ian J. Deary, Pedro Marques-Vidal, Donna K. Arnett, Eleonora Porcu, Jouke-Jan Hottenga, Maria Sabater-Lleal, Bruce M. Psaty, Matthias Nauck, Dan Mellström, Joel Eriksson, Bernhard T. Baune, Debbie A Lawlor, Catherine Toben, Peter H. Whincup, Toshiko Tanaka, Stavroula Kanoni, Katri Räikkönen, Gonneke Willemsen, Bengt Sennblad, Julian N. Trollor, Yalda Jamshidi, Sarah E. Harris, Jari Lahti, Joshua C. Bis, Peter Durda, Yen Pei C. Chang, Jorgen Engmann, Tom R. Gaunt, Stella Aslibekyan, Anbupalam Thalamuthu, Mary F. Feitosa, Angela Silveira, Tine Jess, Stela McLachlan, J. Wouter Jukema, Chen Lu, Simon P. Mooijaart, Tim D. Spector, Harald Grallert, Winfried März, Alexandros M. Petrelis, Manuel A. R. Ferreira, Meena Kumari
Publikováno v:
Human molecular genetics, 30(5), 393-409. Oxford University Press
Human Molecular Genetics, 30(5), 393-409. OXFORD UNIV PRESS
Human Molecular Genetics
Ahluwalia, T S, De Geus, E, Milaneschi, Y, Hottenga, J-J, Van Dongen, J, Willemsen, G, Boomsma, D I, Alizadeh, B Z & CHARGE Inflammation Working Group 2021, ' Genome-Wide Association Study of Circulating Interleukin 6 Levels Identifies Novel Loci ', Human molecular genetics, vol. 30, no. 5, pp. 393-409 . https://doi.org/10.1093/hmg/ddab023
Hum Mol Genet
Human Molecular Genetics, 30(5), 393-409. Oxford University Press
Human molecular genetics, vol. 30, no. 5, pp. 393-409
CHARGE Inflammation working group 2021, ' Genome-wide association study of circulating interleukin 6 levels identifies novel loci ', Human Molecular Genetics, vol. 30, no. 5, pp. 393-409 . https://doi.org/10.1093/hmg/ddab023
Human Molecular Genetics, Oxford University Press (OUP), 2021, ⟨10.1093/hmg/ddab023⟩
Hum. Mol. Genet. 30, 393-409 (2021)
Ahluwalia, T S, Prins, B P, Abdollahi, M, Armstrong, N J, Aslibekyan, S, Bain, L, Jefferis, B, Baumert, J, Beekman, M, Ben-shlomo, Y, Bis, J C, Mitchell, B D, De Geus, E, Delgado, G E, Marek, D, Eriksson, J, Kajantie, E, Kanoni, S, Kemp, J P, Lu, C, Marioni, R E, Mclachlan, S, Milaneschi, Y, Nolte, I M, Petrelis, A M, Porcu, E, Sabater-lleal, M, Naderi, E, Seppälä, I, Shah, T, Singhal, G, Standl, M, Teumer, A, Thalamuthu, A, Thiering, E, Trompet, S, Ballantyne, C M, Benjamin, E J, Casas, J P, Toben, C, Dedoussis, G, Deelen, J, Durda, P, Engmann, J, Feitosa, M F, Grallert, H, Hammarstedt, A, Harris, S E, Homuth, G, Hottenga, J, Jalkanen, S, Jamshidi, Y, Jawahar, M C, Jess, T, Kivimaki, M, Kleber, M E, Lahti, J, Liu, Y, Marques-vidal, P, Mellström, D, Mooijaart, S P, Müller-nurasyid, M, Penninx, B, Revez, J A, Rossing, P, Räikkönen, K, Sattar, N, Scharnagl, H, Sennblad, B, Silveira, A, Pourcain, B S, Timpson, N J, Trollor, J, Van Dongen, J, Van Heemst, D, Visvikis-siest, S, Vollenweider, P, Völker, U, Waldenberger, M, Willemsen, G, Zabaneh, D, Morris, R W, Arnett, D K, Baune, B T, Boomsma, D I, Chang, Y C, Deary, I J, Deloukas, P, Eriksson, J G, Evans, D M, Ferreira, M A, Gaunt, T, Gudnason, V, Hamsten, A, Heinrich, J, Hingorani, A, Humphries, S E, Jukema, J W, Koeing, W, Kumari, M, Kutalik, Z, Lawlor, D A, Lehtimäki, T, März, W, Mather, K, Naitza, S, Nauck, M, Ohlsson, C, Price, J F, Raitakari, O, Rice, K, Sachdev, P S, Slagboom, E, Sørensen, T I A, Spector, T, Stacey, D, Stathopoulou, M G, Tanaka, T, Wannamethee, S G, Whincup, P, Rotter, J I, Dehghan, A, Boerwinkle, E, Psaty, B M, Snieder, H & Alizadeh, B Z 2021, ' Genome-wide association study of circulating Interleukin 6 levels identifies novel loci ', Human Molecular Genetics . https://doi.org/10.1093/hmg/ddab023
European Journal of Human Genetics, 28(SUPPL 1), 307-308. Nature Publishing Group
Ahluwalia, T S, Prins, B P, Abdollahi, M, Armstrong, N J, Aslibekyan, S, Bain, L, Jefferis, B, Baumert, J, Beekman, M, Ben-Shlomo, Y, Bis, J C, Mitchell, B D, de Geus, E, Delgado, G E, Marek, D, Eriksson, J, Kajantie, E, Kanoni, S, Kemp, J P, Lu, C, Marioni, R E, McLachlan, S, Milaneschi, Y, Nolte, I M, Petrelis, A M, Porcu, E, Sabater-Lleal, M, Naderi, E, Seppälä, I, Shah, T, Singhal, G, Standl, M, Teumer, A, Thalamuthu, A, Thiering, E, Trompet, S, Ballantyne, C M, Benjamin, E J, Casas, J P, Toben, C, Dedoussis, G, Deelen, J, Durda, P, Engmann, J, Feitosa, M F, Grallert, H, Hammarstedt, A, Jess, T, Rossing, P, Sørensen, T I A & CHARGE Inflammation Working Group 2021, ' Genome-Wide Association Study of Circulating Interleukin 6 Levels Identifies Novel Loci ', Human Molecular Genetics, vol. 30, no. 5, pp. 393–409 . https://doi.org/10.1093/hmg/ddab023
Human Molecular Genetics, 30(5), 393-409. OXFORD UNIV PRESS
Human Molecular Genetics
Ahluwalia, T S, De Geus, E, Milaneschi, Y, Hottenga, J-J, Van Dongen, J, Willemsen, G, Boomsma, D I, Alizadeh, B Z & CHARGE Inflammation Working Group 2021, ' Genome-Wide Association Study of Circulating Interleukin 6 Levels Identifies Novel Loci ', Human molecular genetics, vol. 30, no. 5, pp. 393-409 . https://doi.org/10.1093/hmg/ddab023
Hum Mol Genet
Human Molecular Genetics, 30(5), 393-409. Oxford University Press
Human molecular genetics, vol. 30, no. 5, pp. 393-409
CHARGE Inflammation working group 2021, ' Genome-wide association study of circulating interleukin 6 levels identifies novel loci ', Human Molecular Genetics, vol. 30, no. 5, pp. 393-409 . https://doi.org/10.1093/hmg/ddab023
Human Molecular Genetics, Oxford University Press (OUP), 2021, ⟨10.1093/hmg/ddab023⟩
Hum. Mol. Genet. 30, 393-409 (2021)
Ahluwalia, T S, Prins, B P, Abdollahi, M, Armstrong, N J, Aslibekyan, S, Bain, L, Jefferis, B, Baumert, J, Beekman, M, Ben-shlomo, Y, Bis, J C, Mitchell, B D, De Geus, E, Delgado, G E, Marek, D, Eriksson, J, Kajantie, E, Kanoni, S, Kemp, J P, Lu, C, Marioni, R E, Mclachlan, S, Milaneschi, Y, Nolte, I M, Petrelis, A M, Porcu, E, Sabater-lleal, M, Naderi, E, Seppälä, I, Shah, T, Singhal, G, Standl, M, Teumer, A, Thalamuthu, A, Thiering, E, Trompet, S, Ballantyne, C M, Benjamin, E J, Casas, J P, Toben, C, Dedoussis, G, Deelen, J, Durda, P, Engmann, J, Feitosa, M F, Grallert, H, Hammarstedt, A, Harris, S E, Homuth, G, Hottenga, J, Jalkanen, S, Jamshidi, Y, Jawahar, M C, Jess, T, Kivimaki, M, Kleber, M E, Lahti, J, Liu, Y, Marques-vidal, P, Mellström, D, Mooijaart, S P, Müller-nurasyid, M, Penninx, B, Revez, J A, Rossing, P, Räikkönen, K, Sattar, N, Scharnagl, H, Sennblad, B, Silveira, A, Pourcain, B S, Timpson, N J, Trollor, J, Van Dongen, J, Van Heemst, D, Visvikis-siest, S, Vollenweider, P, Völker, U, Waldenberger, M, Willemsen, G, Zabaneh, D, Morris, R W, Arnett, D K, Baune, B T, Boomsma, D I, Chang, Y C, Deary, I J, Deloukas, P, Eriksson, J G, Evans, D M, Ferreira, M A, Gaunt, T, Gudnason, V, Hamsten, A, Heinrich, J, Hingorani, A, Humphries, S E, Jukema, J W, Koeing, W, Kumari, M, Kutalik, Z, Lawlor, D A, Lehtimäki, T, März, W, Mather, K, Naitza, S, Nauck, M, Ohlsson, C, Price, J F, Raitakari, O, Rice, K, Sachdev, P S, Slagboom, E, Sørensen, T I A, Spector, T, Stacey, D, Stathopoulou, M G, Tanaka, T, Wannamethee, S G, Whincup, P, Rotter, J I, Dehghan, A, Boerwinkle, E, Psaty, B M, Snieder, H & Alizadeh, B Z 2021, ' Genome-wide association study of circulating Interleukin 6 levels identifies novel loci ', Human Molecular Genetics . https://doi.org/10.1093/hmg/ddab023
European Journal of Human Genetics, 28(SUPPL 1), 307-308. Nature Publishing Group
Ahluwalia, T S, Prins, B P, Abdollahi, M, Armstrong, N J, Aslibekyan, S, Bain, L, Jefferis, B, Baumert, J, Beekman, M, Ben-Shlomo, Y, Bis, J C, Mitchell, B D, de Geus, E, Delgado, G E, Marek, D, Eriksson, J, Kajantie, E, Kanoni, S, Kemp, J P, Lu, C, Marioni, R E, McLachlan, S, Milaneschi, Y, Nolte, I M, Petrelis, A M, Porcu, E, Sabater-Lleal, M, Naderi, E, Seppälä, I, Shah, T, Singhal, G, Standl, M, Teumer, A, Thalamuthu, A, Thiering, E, Trompet, S, Ballantyne, C M, Benjamin, E J, Casas, J P, Toben, C, Dedoussis, G, Deelen, J, Durda, P, Engmann, J, Feitosa, M F, Grallert, H, Hammarstedt, A, Jess, T, Rossing, P, Sørensen, T I A & CHARGE Inflammation Working Group 2021, ' Genome-Wide Association Study of Circulating Interleukin 6 Levels Identifies Novel Loci ', Human Molecular Genetics, vol. 30, no. 5, pp. 393–409 . https://doi.org/10.1093/hmg/ddab023
Interleukin 6 (IL-6) is a multifunctional cytokine with both pro- and anti-inflammatory properties with a heritability estimate of up to 61%. The circulating levels of IL-6 in blood have been associated with an increased risk of complex disease patho
Autor:
Nicholas J. Timpson, Jackie F. Price, Henning Tiemeier, Caroline Hayward, Stephan J. L. Bakker, Christian Gieger, Tom Michoel, Catriona L. K. Barnes, Ville Karhunen, Peter K. Joshi, Katyayani Sukhavasi, Anubha Mahajan, Carol A. Wang, Igor Rudan, Maik Pietzner, Andrew P. Morris, Craig E. Pennell, Andrew A Crawford, Marjo-Riitta Järvelin, Henry Völzke, Harry Campbell, Johan L.M. Björkegren, Pim van der Harst, David W. Clark, Massimo Mangino, Claes Ohlsson, Tim D. Spector, Jari Lahti, Elisabeth Altmaier, Johan G. Eriksson, Alexander Neumann, Raili Ermel, Maria Nethander, Arno Ruusalepp, James R M Wilson, George Davey Smith, Nele Friedrich, Sean Bankier, Brian R. Walker, Stela McLachlan
Publikováno v:
Journal of human genetics
Journal of Human Genetics
Crawford, A, Bankier, S, Altmaier, E, Barnes, C L K, Clark, D W, Ermel, R, Friedrich, N, van der Harst, P, Joshi, P K, Karhunen, V, Lahti, J, Mahajan, A, Mangino, M, Nethander, M, Neumann, A, Pietzne, M, Sukhavasi, K, Wang, C A, Bakker, S J L, Björkegren, J L M, Campbell, H, Eriksson, J, Gieger, C, Hayward, C, Jarvelin, M-R, McLachlan, S, Morris, A P, Ohlsson, C, Pennell, C E, Price, J F, Rudan, I, Ruusalepp, A, Spector, T D, Tiemeier, H, Völzke, H, Wilson, J F, Michoel, T, Timpson, N J, Davey Smith, G & Walker, B R 2021, ' Variation in the SERPINA6SERPINA1 locusalters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expressionin peripheral tissues, and risk of cardiovascular disease ', Journal of Human Genetics . https://doi.org/10.1038/s10038-020-00895-6
Journal of human genetics, 66(6), 625-636. Nature Publishing Group
Journal of Human Genetics, 66(6), 625-636. Nature Publishing Group
Crawford, A A, Bankier, S, Altmaier, E, Barnes, C L K, Clark, D W, Ermel, R, Friedrich, N, Van Der Harst, P, Joshi, P K, Karhunen, V, Lahti, J, Mahajan, A, Mangino, M, Nethander, M, Neumann, A, Pietzner, M, Sukhavasi, K, Wang, C A, Bakker, S J L, Bjorkegren, J L M, Campbell, H, Eriksson, J, Gieger, C, Hayward, C, Jarvelin, M, Mclachlan, S, Morris, A P, Ohlsson, C, Pennell, C E, Price, J, Rudan, I, Ruusalepp, A, Spector, T, Tiemeier, H, Völzke, H, Wilson, J F, Michoel, T, Timpson, N J, Smith, G D & Walker, B R 2021, ' Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease ', Journal of Human Genetics, vol. 66, no. 6, pp. 625-636 . https://doi.org/10.1038/s10038-020-00895-6
J. Hum. Genet. 66, 625–636 (2021)
Crawford, A A, Bankier, S, Altmaier, E, Barnes, C L K, Clark, D W, Ermel, R, Friedrich, N, Van Der Harst, P, Joshi, P K, Karhunen, V, Lahti, J, Mahajan, A, Mangino, M, Nethander, M, Neumann, A, Pietzner, M, Sukhavasi, K, Wang, C A, Bakker, S J L, Björkegren, J L M, Campbell, H, Eriksson, J, Gieger, C, Hayward, C, Jarvelin, M-R, McLachlan, S, Morris, A P, Ohlsson, C, Pennell, C E, Price, J F, Rudan, I, Ruusalepp, A, Spector, T D, Tiemeier, H, Völzke, H, Wilson, J R M, Michoel, T, Timpson, N J, Davey Smith, G & Walker, B R 2021, ' Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease ', Journal of Human Genetics, vol. 66, no. 6, pp. 625-636 . https://doi.org/10.1038/s10038-020-00895-6
Journal of Human Genetics
Crawford, A, Bankier, S, Altmaier, E, Barnes, C L K, Clark, D W, Ermel, R, Friedrich, N, van der Harst, P, Joshi, P K, Karhunen, V, Lahti, J, Mahajan, A, Mangino, M, Nethander, M, Neumann, A, Pietzne, M, Sukhavasi, K, Wang, C A, Bakker, S J L, Björkegren, J L M, Campbell, H, Eriksson, J, Gieger, C, Hayward, C, Jarvelin, M-R, McLachlan, S, Morris, A P, Ohlsson, C, Pennell, C E, Price, J F, Rudan, I, Ruusalepp, A, Spector, T D, Tiemeier, H, Völzke, H, Wilson, J F, Michoel, T, Timpson, N J, Davey Smith, G & Walker, B R 2021, ' Variation in the SERPINA6SERPINA1 locusalters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expressionin peripheral tissues, and risk of cardiovascular disease ', Journal of Human Genetics . https://doi.org/10.1038/s10038-020-00895-6
Journal of human genetics, 66(6), 625-636. Nature Publishing Group
Journal of Human Genetics, 66(6), 625-636. Nature Publishing Group
Crawford, A A, Bankier, S, Altmaier, E, Barnes, C L K, Clark, D W, Ermel, R, Friedrich, N, Van Der Harst, P, Joshi, P K, Karhunen, V, Lahti, J, Mahajan, A, Mangino, M, Nethander, M, Neumann, A, Pietzner, M, Sukhavasi, K, Wang, C A, Bakker, S J L, Bjorkegren, J L M, Campbell, H, Eriksson, J, Gieger, C, Hayward, C, Jarvelin, M, Mclachlan, S, Morris, A P, Ohlsson, C, Pennell, C E, Price, J, Rudan, I, Ruusalepp, A, Spector, T, Tiemeier, H, Völzke, H, Wilson, J F, Michoel, T, Timpson, N J, Smith, G D & Walker, B R 2021, ' Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease ', Journal of Human Genetics, vol. 66, no. 6, pp. 625-636 . https://doi.org/10.1038/s10038-020-00895-6
J. Hum. Genet. 66, 625–636 (2021)
Crawford, A A, Bankier, S, Altmaier, E, Barnes, C L K, Clark, D W, Ermel, R, Friedrich, N, Van Der Harst, P, Joshi, P K, Karhunen, V, Lahti, J, Mahajan, A, Mangino, M, Nethander, M, Neumann, A, Pietzner, M, Sukhavasi, K, Wang, C A, Bakker, S J L, Björkegren, J L M, Campbell, H, Eriksson, J, Gieger, C, Hayward, C, Jarvelin, M-R, McLachlan, S, Morris, A P, Ohlsson, C, Pennell, C E, Price, J F, Rudan, I, Ruusalepp, A, Spector, T D, Tiemeier, H, Völzke, H, Wilson, J R M, Michoel, T, Timpson, N J, Davey Smith, G & Walker, B R 2021, ' Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and risk of cardiovascular disease ', Journal of Human Genetics, vol. 66, no. 6, pp. 625-636 . https://doi.org/10.1038/s10038-020-00895-6
The stress hormone cortisol modulates fuel metabolism, cardiovascular homoeostasis, mood, inflammation and cognition. The CORtisol NETwork (CORNET) consortium previously identified a single locus associated with morning plasma cortisol. Identifying a
Autor:
Unnur Styrkarsdottir, Lynda M. Rose, Rehannah Borup, Anne B. Newman, Georgia Chenevix-Trench, Chikashi Terao, Jeremy A. Daniel, Christa Meisinger, Albert V. Smith, Emil Peter Thrane Hertz, Raymond Noordam, Wei He, Jennifer A. Smith, Mikael Eriksson, Konstantin Strauch, Daniel I. Chasman, Nicholas J. Timpson, Melissa A. Troester, Claudia Langenberg, Montserrat Garcia-Closas, Mohammad Arfan Ikram, Sara Lindström, Gad Rennert, Pascal Guénel, Kristina W. Olsen, Pierre Fontanillas, Ozren Polasek, Daniel F. Gudbjartsson, Frank B. Hu, Archie Campbell, Celine M. Vachon, Sheila Ulivi, Robin N Beaumont, Robert Karlsson, Lenore J. Launer, Renée de Mutsert, Annette Peters, David Schlessinger, Stefania Bandinelli, Rico Rueedi, Joop S.E. Laven, Pascal Timshel, Joanne M. Murabito, Kuang Lin, Jazib Hussain, Dennis O. Mook-Kanamori, Manjeet K. Bolla, Catherine E. Aiken, Javier Martin Gonzalez, Simon S. Cross, Immaculata De Vivo, Paul M. Ridker, Christopher A. Haiman, Gerardo Heiss, Jessica Tyrrell, Paul R. H. J. Timmers, Hironori Abe, Mike A. Nalls, Luigi Ferrucci, Natalia Perjakova, Jouke J. Hottenga, Robin G. Walters, Reedik Mägi, Niclas Håkansson, Miriam Dwek, Barbara McKnight, Sandra Turon, Stasa Stankovic, Linda Broer, Stephen J. Chanock, Martina La Bianca, Jenny Chang-Claude, Loic Le Marchand, Hamdi Mbarek, Doris Stöckl, Andrew F. Olshan, Graham G. Giles, James F. Wilson, Micaella Joaquim, Amruta Shrikhande, Eva Hoffmann, Stefania Benonisdottir, Ana Martínez-Marchal, Anthony J. Swerdlow, David Karasik, Nicholas J. Wareham, Peter A. Fasching, Jane L. Tarry-Adkins, Charles Kooperberg, Peter Vollenweider, Douglas F. Easton, Paula Aguilera, Jessica D. Faul, Patrik K. E. Magnusson, Emmanouil Saloustros, Alpa V. Patel, Ellen W. Demerath, Qin Wang, Aditya Sankar, Christopher G. Scott, Iffat Rahman, Sharon L.R. Kardia, Peter K. Joshi, Caterina Barbieri, Claus Yding Andersen, Tõnu Esko, Massimo Mezzavilla, Nicholas G. Martin, Rebecca D. Jackson, Alison D. Murray, Marina Ciullo, Nicholas Bowker, Anna Murray, Patrick Deelen, Zoltán Kutalik, Alicja Wolk, Manuela Gago-Dominguez, Eleonora Porcu, Laura Crisponi, Michela Traglia, Katharina E. Schraut, Antonietta Robino, Chunyan He, Bruce H. R. Wolffenbuttel, Henry Völzke, Daniela Ruggiero, John R. B. Perry, Lude Franke, Igor Rudan, Angela Cox, Unnur Þorsteinsdottir, Christian Gieger, David R. Weir, Jodie N. Painter, Martha S. Linet, Massimo Mangino, Melissa C. Southey, Petr Solc, Tim D. Spector, Christiana Kartsonaki, Momoko Horikoshi, Meir J. Stampfer, Eulalia Catamo, Mònica Ferrer-Roda, Ko Willems van Dijk, Daniela Toniolo, Caroline Hayward, Lili Milani, Chloé Sarnowski, Jian'an Luan, Behrooz Z. Alizadeh, Jenny A. Visser, Stig E. Bojesen, Genevieve Lachance, Ulrike Peters, Antonella Mulas, John J. Spinelli, Elnaz Naderi, Andrew R. Wood, Paul D.P. Pharoah, Elinor J. Sawyer, Annique Claringbould, Saleh Shekari, David G. Hunter, Marie Louise Grøndahl, Vilmundur Gudnason, Nora Franceschini, Dale P. Sandler, Dale R. Nyholt, Jacques E. Rossouw, Amber N. Wilcox, Thomas U. Ahearn, Hedy S. Rennert, Olivier B. Bakker, Jingmei Li, Francesco Cucca, Eric Boerwinkle, Matthias W. Beckmann, Cristina Menni, Minouk J. Schoemaker, Esther M. John, Tune H. Pers, Andrés J. López-Contreras, Tanguy Corre, Jonathan Marten, Alice M. Arnold, N. Charlotte Onland-Moret, Lucie Knoblochova, Anna Pujol, Kathryn L. Lunetta, Marjanka K. Schmidt, Teresa Nutile, Serena Sanna, Gonneke Willemsen, Roger L. Milne, Kristan J. Aronson, Frits R. Rosendaal, Murielle Bochud, Ken K. Ong, Susan M. Ring, Nancy L. Pedersen, Blair H. Smith, Ivana Kolcic, Annelie Augustinsson, Jose E. Castelao, Alexander Teumer, Felix R. Day, Sven Bergmann, Timothy M. Frayling, Lauren R. Teras, George Davey Smith, Thomas Meitinger, Alison M. Dunning, Ignasi Roig, Dorret I. Boomsma, Harald Grallert, Toshiko Tanaka, Katherine S. Ruth, Julie E. Buring, Marek Zygmunt, Uwe Völker, Irene L. Andrulis, Håkan Olsson, Harry Campbell, Cari M. Kitahara, Annika Lindblom, Yvonne T. van der Schouw, Cinzia Sala, Debbie A Lawlor, Joe Dennis, Yongmei Liu, Yan Huang, Stephen Burgess, Brumat Marco, Veronique Vitart, Kari Stefansson, Susan E. Ozanne, Kamila Czene, Simin Liu, John L. Hopper, Joyce B. J. van Meurs, Satoshi H. Namekawa, Miya Kudo Høffding, Fergus J. Couch, Ajuna Azad, Eco J. C. de Geus, Liming Li, Grant W. Montgomery, Peter Kraft, André G. Uitterlinden, Arto Mannermaa, Heiko Becher, Allison W. Kurian, Vallari Shukla, Zhengming Chen, Per Hall, Jennifer A. Brody, Rossella Sorice, Wei Zhao, Andres Metspalu, Sarah E. Medland, Tricia Lindstrom, Clarice R. Weinberg, Bruce M. Psaty, Thérèse Truong, Anna Marie Mulligan, Deborah J. Thompson, Patrick Sulem
Publikováno v:
University of Bristol-PURE
Nature, 596(7872), 393-397. NATURE PORTFOLIO
Nature 596, 393-397 (2021)
Nature, 596(7872), 393-397. Nature Publishing Group
Nature (Lond.) 596 (2021): 393–397. doi:10.1038/s41586-021-03779-7
info:cnr-pdr/source/autori:Ruth K.S.; Day F.R.; Hussain J.; Martinez-Marchal A.; Aiken C.E.; Azad A.; Thompson D.J.; Knoblochova L.; Abe H.; Tarry-Adkins J.L.; Gonzalez J.M.; Fontanillas P.; Claringbould A.; Bakker O.B.; Sulem P.; Walters R.G.; Terao C.; Turon S.; Horikoshi M.; Lin K.; Onland-Moret N.C.; Sankar A.; Hertz E.P.T.; Timshel P.N.; Shukla V.; Borup R.; Olsen K.W.; Aguilera P.; Ferrer-Roda M.; Huang Y.; Stankovic S.; Timmers P.R.H.J.; Ahearn T.U.; Alizadeh B.Z.; Naderi E.; Andrulis I.L.; Arnold A.M.; Aronson K.J.; Augustinsson A.; Bandinelli S.; Barbieri C.M.; Beaumont R.N.; Becher H.; Beckmann M.W.; Benonisdottir S.; Bergmann S.; Bochud M.; Boerwinkle E.; Bojesen S.E.; Bolla M.K.; Boomsma D.I.; Bowker N.; Brody J.A.; Broer L.; Buring J.E.; Campbell A.; Campbell H.; Castelao J.E.; Catamo E.; Chanock S.J.; Chenevix-Trench G.; Ciullo M.; Corre T.; Couch F.J.; Cox A.; Crisponi L.; Cross S.S.; Cucca F.; Czene K.; Smith G.D.; de Geus E.J.C.N.; de Mutsert R.; De Vivo I.; Demerath E.W.; Dennis J.; Dunning A.M.; Dwek M.; Eriksson M.; Esko T.; Fasching P.A.; Faul J.D.; Ferrucci L.; Franceschini N.; Frayling T.M.; Gago-Dominguez M.; Mezzavilla M.; Garcia-Closas M.; Gieger C.; Giles G.G.; Grallert H.; Gudbjartsson D.F.; Gudnason V.; Guenel P.; Haiman C.A.; Hakansson N.; Hall P.; Hayward C.; He C.; He W.; Heiss G.; Hoffding M.K.; Hopper J.L.; Hottenga J.J.; Hu F.; Hunter D.; Ikram M.A.; Jackson R.D.; Joaquim M.D.R.; John E.M.; Joshi P.K.; Karasik D.; Kardia S.L.R.; Kartsonaki C.; Karlsson R.; Kitahara C.M.; Kolcic I.; Kooperberg C.; Kraft P.; Kurian A.W.; Kutalik Z.; La Bianca M.; LaChance G.; Langenberg C.; Launer L.J.; Laven J.S.E.; Lawlor D.A.; Le Marchand L.; Li J.; Lindblom A.; Lindstrom S.; Lindstrom T.; Linet M.; Liu Y.M.; Liu S.; Luan J.; Magi R.; Magnusson P.K.E.; Mangino M.; Mannermaa A.; Marco B.; Marten J.; Martin N.G.; Mbarek H.; McKnight B.; Medland S.E.; Meisinger C.; Meitinger T.; Menni C.; Metspalu A.; Milani L.; Milne R.L.; Montgomery G.W.; Mook-Kanamori D.O.; Mulas A.; Mulligan A.M.; Murray A.; Nalls M.A.; Newman A.; Noordam R.; Nutile T.; Nyholt D.R.; Olshan A.F.; Olsson H.; Painter J.N.; Patel A.V.; Pedersen N.L.; Perjakova N.; Peters A.; Peters U.; Pharoah P.D.P.; Polasek O.; Porcu E.; Psaty B.M.; Rahman I.; Rennert G.; Rennert H.S.; Ridker P.M.; Ring S.M.; Robino A.; Rose L.M.; Rosendaal F.R.; Rossouw J.; Rudan I.; Rueedi R.; Ruggiero D.; Sala C.F.; Saloustros E.; Sandler D.P.; Sanna S.; Sawyer E.J.; Sarnowski C.; Schlessinger D.; Schmidt M.K.; Schoemaker M.J.; Schraut K.E.; Scott C.; Shekari S.; Shrikhande A.; Smith A.V.; Smith B.H.; Smith J.A.; Sorice R.; Southey M.C.; Spector T.D.; Spinelli J.J.; Stampfer M.; Stockl D.; van Meurs J.B.J.; Strauch K.; Styrkarsdottir U.; Swerdlow A.J.; Tanaka T.; Teras L.R.; Teumer A.; Thorsteinsdottir U.; Timpson N.J.; Toniolo D.; Traglia M.; Troester M.A.; Truong T.; Tyrrell J.; Uitterlinden A.G.; Ulivi S.; Vachon C.M.; Vitart V.; Volker U.; Vollenweider P.; Volzke H.; Wang Q.; Wareham N.J.; Weinberg C.R.; Weir D.R.; Wilcox A.N.; van Dijk K.W.; Willemsen G.; Wilson J.F.; Wolffenbuttel B.H.R.; Wolk A.; Wood A.R.; Zhao W.; Zygmunt M.; Chen Z.; Li L.; Franke L.; Burgess S.; Deelen P.; Pers T.H.; Grondahl M.L.; Andersen C.Y.; Pujol A.; Lopez-Contreras A.J.; Daniel J.A.; Stefansson K.; Chang-Claude J.; van der Schouw Y.T.; Lunetta K.L.; Chasman D.I.; Easton D.F.; Visser J.A.; Ozanne S.E.; Namekawa S.H.; Solc P.; Murabito J.M.; Ong K.K.; Hoffmann E.R.; Murray A.; Roig I.; Perry J.R.B./titolo:Genetic insights into biological mechanisms governing human ovarian ageing/doi:10.1038%2Fs41586-021-03779-7/rivista:Nature (Lond.)/anno:2021/pagina_da:393/pagina_a:397/intervallo_pagine:393–397/volume:596
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature
Ruth, K S, Day, F R, Hussain, J, Martinez-Marchal, A, Aiken, C E, Azad, A, Thompson, D J, Knoblochova, L, Abe, H, Tarry-Adkins, J L, Gonzalez, J M, Fontanillas, P, Claringbould, A, Bakker, O B, Sulem, P, Walters, R G, Terao, C, Turon, S, Horikoshi, M, Lin, K, Onland-Moret, N C, Sankar, A, Hertz, E P T, Timshel, P N, Shukla, V, Borup, R, Olsen, K W, Aguilera, P, Ferrer-Roda, M, Huang, Y, Stankovic, S, Timmers, P R H J, Ahearn, T U, Alizadeh, B Z, Naderi, E, Andrulis, I L, Arnold, A M, Aronson, K J, Augustinsson, A, Bojesen, S E, Hoffding, M K, Shrikhande, A, Pers, T H, Grøndahl, M L, Andersen, C Y, Lopez-Contreras, A J, Daniel, J A, Hoffmann, E R, Biobank-based Integrative Omics St, eQTLGen Consortium, BioBank Japan Project, China Kadoorie Biobank Collaborati, kConFab Investigators, LifeLines Cohort Study, InterAct Consortium & 23 Me Res Team 2021, ' Genetic insights into biological mechanisms governing human ovarian ageing ', Nature, vol. 596, pp. 393-397 . https://doi.org/10.1038/s41586-021-03779-7
Ruth, K S, Davey Smith, G, Lawlor, D A, Ring, S M, Timpson, N J, Perry, J R B & al., E 2021, ' Genetic insights into biological mechanisms governing human ovarian ageing ', Nature . https://doi.org/10.1038/s41586-021-03779-7
Ruth, K S, Boomsma, D I, de Geus, E J C N, Hottenga, J J, Willemsen, G, Murray, A, Perry, J R B, China Kadoorie Biobank Collaborative Group, kConFab Investigators, The LifeLines Cohort Study, The InterAct consortium, 23Andme Research Team, Biobank-based Integrative Omics Study (BIOS) Consortium, eQTLGen Consortium & The Biobank Japan Project 2021, ' Genetic insights into biological mechanisms governing human ovarian ageing ', Nature, vol. 596, no. 7872, pp. 393-397 . https://doi.org/10.1038/s41586-021-03779-7
2021, ' Genetic insights into biological mechanisms governing human ovarian ageing ', Nature . https://doi.org/10.1038/s41586-021-03779-7
Nature, 596(7872), 393-397. NATURE PORTFOLIO
Nature 596, 393-397 (2021)
Nature, 596(7872), 393-397. Nature Publishing Group
Nature (Lond.) 596 (2021): 393–397. doi:10.1038/s41586-021-03779-7
info:cnr-pdr/source/autori:Ruth K.S.; Day F.R.; Hussain J.; Martinez-Marchal A.; Aiken C.E.; Azad A.; Thompson D.J.; Knoblochova L.; Abe H.; Tarry-Adkins J.L.; Gonzalez J.M.; Fontanillas P.; Claringbould A.; Bakker O.B.; Sulem P.; Walters R.G.; Terao C.; Turon S.; Horikoshi M.; Lin K.; Onland-Moret N.C.; Sankar A.; Hertz E.P.T.; Timshel P.N.; Shukla V.; Borup R.; Olsen K.W.; Aguilera P.; Ferrer-Roda M.; Huang Y.; Stankovic S.; Timmers P.R.H.J.; Ahearn T.U.; Alizadeh B.Z.; Naderi E.; Andrulis I.L.; Arnold A.M.; Aronson K.J.; Augustinsson A.; Bandinelli S.; Barbieri C.M.; Beaumont R.N.; Becher H.; Beckmann M.W.; Benonisdottir S.; Bergmann S.; Bochud M.; Boerwinkle E.; Bojesen S.E.; Bolla M.K.; Boomsma D.I.; Bowker N.; Brody J.A.; Broer L.; Buring J.E.; Campbell A.; Campbell H.; Castelao J.E.; Catamo E.; Chanock S.J.; Chenevix-Trench G.; Ciullo M.; Corre T.; Couch F.J.; Cox A.; Crisponi L.; Cross S.S.; Cucca F.; Czene K.; Smith G.D.; de Geus E.J.C.N.; de Mutsert R.; De Vivo I.; Demerath E.W.; Dennis J.; Dunning A.M.; Dwek M.; Eriksson M.; Esko T.; Fasching P.A.; Faul J.D.; Ferrucci L.; Franceschini N.; Frayling T.M.; Gago-Dominguez M.; Mezzavilla M.; Garcia-Closas M.; Gieger C.; Giles G.G.; Grallert H.; Gudbjartsson D.F.; Gudnason V.; Guenel P.; Haiman C.A.; Hakansson N.; Hall P.; Hayward C.; He C.; He W.; Heiss G.; Hoffding M.K.; Hopper J.L.; Hottenga J.J.; Hu F.; Hunter D.; Ikram M.A.; Jackson R.D.; Joaquim M.D.R.; John E.M.; Joshi P.K.; Karasik D.; Kardia S.L.R.; Kartsonaki C.; Karlsson R.; Kitahara C.M.; Kolcic I.; Kooperberg C.; Kraft P.; Kurian A.W.; Kutalik Z.; La Bianca M.; LaChance G.; Langenberg C.; Launer L.J.; Laven J.S.E.; Lawlor D.A.; Le Marchand L.; Li J.; Lindblom A.; Lindstrom S.; Lindstrom T.; Linet M.; Liu Y.M.; Liu S.; Luan J.; Magi R.; Magnusson P.K.E.; Mangino M.; Mannermaa A.; Marco B.; Marten J.; Martin N.G.; Mbarek H.; McKnight B.; Medland S.E.; Meisinger C.; Meitinger T.; Menni C.; Metspalu A.; Milani L.; Milne R.L.; Montgomery G.W.; Mook-Kanamori D.O.; Mulas A.; Mulligan A.M.; Murray A.; Nalls M.A.; Newman A.; Noordam R.; Nutile T.; Nyholt D.R.; Olshan A.F.; Olsson H.; Painter J.N.; Patel A.V.; Pedersen N.L.; Perjakova N.; Peters A.; Peters U.; Pharoah P.D.P.; Polasek O.; Porcu E.; Psaty B.M.; Rahman I.; Rennert G.; Rennert H.S.; Ridker P.M.; Ring S.M.; Robino A.; Rose L.M.; Rosendaal F.R.; Rossouw J.; Rudan I.; Rueedi R.; Ruggiero D.; Sala C.F.; Saloustros E.; Sandler D.P.; Sanna S.; Sawyer E.J.; Sarnowski C.; Schlessinger D.; Schmidt M.K.; Schoemaker M.J.; Schraut K.E.; Scott C.; Shekari S.; Shrikhande A.; Smith A.V.; Smith B.H.; Smith J.A.; Sorice R.; Southey M.C.; Spector T.D.; Spinelli J.J.; Stampfer M.; Stockl D.; van Meurs J.B.J.; Strauch K.; Styrkarsdottir U.; Swerdlow A.J.; Tanaka T.; Teras L.R.; Teumer A.; Thorsteinsdottir U.; Timpson N.J.; Toniolo D.; Traglia M.; Troester M.A.; Truong T.; Tyrrell J.; Uitterlinden A.G.; Ulivi S.; Vachon C.M.; Vitart V.; Volker U.; Vollenweider P.; Volzke H.; Wang Q.; Wareham N.J.; Weinberg C.R.; Weir D.R.; Wilcox A.N.; van Dijk K.W.; Willemsen G.; Wilson J.F.; Wolffenbuttel B.H.R.; Wolk A.; Wood A.R.; Zhao W.; Zygmunt M.; Chen Z.; Li L.; Franke L.; Burgess S.; Deelen P.; Pers T.H.; Grondahl M.L.; Andersen C.Y.; Pujol A.; Lopez-Contreras A.J.; Daniel J.A.; Stefansson K.; Chang-Claude J.; van der Schouw Y.T.; Lunetta K.L.; Chasman D.I.; Easton D.F.; Visser J.A.; Ozanne S.E.; Namekawa S.H.; Solc P.; Murabito J.M.; Ong K.K.; Hoffmann E.R.; Murray A.; Roig I.; Perry J.R.B./titolo:Genetic insights into biological mechanisms governing human ovarian ageing/doi:10.1038%2Fs41586-021-03779-7/rivista:Nature (Lond.)/anno:2021/pagina_da:393/pagina_a:397/intervallo_pagine:393–397/volume:596
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature
Ruth, K S, Day, F R, Hussain, J, Martinez-Marchal, A, Aiken, C E, Azad, A, Thompson, D J, Knoblochova, L, Abe, H, Tarry-Adkins, J L, Gonzalez, J M, Fontanillas, P, Claringbould, A, Bakker, O B, Sulem, P, Walters, R G, Terao, C, Turon, S, Horikoshi, M, Lin, K, Onland-Moret, N C, Sankar, A, Hertz, E P T, Timshel, P N, Shukla, V, Borup, R, Olsen, K W, Aguilera, P, Ferrer-Roda, M, Huang, Y, Stankovic, S, Timmers, P R H J, Ahearn, T U, Alizadeh, B Z, Naderi, E, Andrulis, I L, Arnold, A M, Aronson, K J, Augustinsson, A, Bojesen, S E, Hoffding, M K, Shrikhande, A, Pers, T H, Grøndahl, M L, Andersen, C Y, Lopez-Contreras, A J, Daniel, J A, Hoffmann, E R, Biobank-based Integrative Omics St, eQTLGen Consortium, BioBank Japan Project, China Kadoorie Biobank Collaborati, kConFab Investigators, LifeLines Cohort Study, InterAct Consortium & 23 Me Res Team 2021, ' Genetic insights into biological mechanisms governing human ovarian ageing ', Nature, vol. 596, pp. 393-397 . https://doi.org/10.1038/s41586-021-03779-7
Ruth, K S, Davey Smith, G, Lawlor, D A, Ring, S M, Timpson, N J, Perry, J R B & al., E 2021, ' Genetic insights into biological mechanisms governing human ovarian ageing ', Nature . https://doi.org/10.1038/s41586-021-03779-7
Ruth, K S, Boomsma, D I, de Geus, E J C N, Hottenga, J J, Willemsen, G, Murray, A, Perry, J R B, China Kadoorie Biobank Collaborative Group, kConFab Investigators, The LifeLines Cohort Study, The InterAct consortium, 23Andme Research Team, Biobank-based Integrative Omics Study (BIOS) Consortium, eQTLGen Consortium & The Biobank Japan Project 2021, ' Genetic insights into biological mechanisms governing human ovarian ageing ', Nature, vol. 596, no. 7872, pp. 393-397 . https://doi.org/10.1038/s41586-021-03779-7
2021, ' Genetic insights into biological mechanisms governing human ovarian ageing ', Nature . https://doi.org/10.1038/s41586-021-03779-7
Reproductive longevity is essential for fertility and influences healthy ageing in women1,2, but insights into its underlying biological mechanisms and treatments to preserve it are limited. Here we identify 290 genetic determinants of ovarian ageing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c116da3463b05311b0eb7aaf58170e4e
https://hdl.handle.net/1887/3217417
https://hdl.handle.net/1887/3217417
Autor:
Matteo D’Antonio, Jennifer P. Nguyen, Timothy D. Arthur, Hiroko Matsui, Agnieszka D’Antonio-Chronowska, Kelly A. Frazer, Benjamin M. Neale, Mark Daly, Andrea Ganna, Christine Stevens, Gita A. Pathak, Shea J. Andrews, Masahiro Kanai, Mattia Cordioli, Juha Karjalainen, Renato Polimanti, Matti Pirinen, Nadia Harerimana, Kumar Veerapen, Brooke Wolford, Huy Nguyen, Matthew Solomonson, Rachel G. Liao, Karolina Chwialkowska, Amy Trankiem, Mary K. Balaconis, Caroline Hayward, Anne Richmond, Archie Campbell, Marcela Morris, Chloe Fawns-Ritchie, Joseph T. Glessner, Douglas M. Shaw, Xiao Chang, Hannah Polikowski, Petty E. Lauren, Hung-Hsin Chen, Zhu Wanying, Hakon Hakonarson, David J. Porteous, Jennifer Below, Kari North, Joseph B. McCormick, Paul R.H.J. Timmers, James F. Wilson, Albert Tenesa, Kenton D’Mellow, Shona M. Kerr, Mari E.K. Niemi, Lindokuhle Nkambul, Kathrin Aprile von Hohenstaufen, Ali Sobh, Madonna M. Eltoukhy, Amr M. Yassen, Mohamed A.F. Hegazy, Kamal Okasha, Mohammed A. Eid, Hanteera S. Moahmed, Doaa Shahin, Yasser M. El-Sherbiny, Tamer A. Elhadidy, Mohamed S. Abd Elghafar, Jehan J. El-Jawhari, Attia A.S. Mohamed, Marwa H. Elnagdy, Amr Samir, Mahmoud Abdel-Aziz, Walid T. Khafaga, Walaa M. El-Lawaty, Mohamed S. Torky, Mohamed R. El-shanshory, Chiara Batini, Paul H. Lee, Nick Shrine, Alexander T. Williams, Martin D. Tobin, Anna L. Guyatt, Catherine John, Richard J. Packer, Altaf Ali, Robert C. Free, Xueyang Wang, Louise V. Wain, Edward J. Hollox, Laura D. Venn, Catherine E. Bee, Emma L. Adams, Ahmadreza Niavarani, Bahareh Sharififard, Rasoul Aliannejad, Ali Amirsavadkouhi, Zeinab Naderpour, Hengameh Ansari Tadi, Afshar Etemadi Aleagha, Saeideh Ahmadi, Seyed Behrooz Mohseni Moghaddam, Alireza Adamsara, Morteza Saeedi, Hamed Abdollahi, Abdolmajid Hosseini, Pajaree Chariyavilaskul, Monpat Chamnanphon, Thitima B. Suttichet, Vorasuk Shotelersuk, Monnat Pongpanich, Chureerat Phokaew, Wanna Chetruengchai, Watsamon Jantarabenjakul, Opass Putchareon, Pattama Torvorapanit, Thanyawee Puthanakit, Pintip Suchartlikitwong, Nattiya Hirankarn, Voraphoj Nilaratanakul, Pimpayao Sodsai, Ben M. Brumpton, Kristian Hveem, Cristen Willer, Wei Zhou, Tormod Rogne, Erik Solligard, Bjørn Olav Åsvold, Malak Abedalthagafi, Manal Alaamery, Saleh Alqahtani, Dona Baraka, Fawz Al Harthi, Ebtehal Alsolm, Leen Abu Safieh, Albandary M. Alowayn, Fatimah Alqubaishi, Amal Al Mutairi, Serghei Mangul, Abdulraheem Alshareef, Mona Sawaji, Mansour Almutairi, Nora Aljawini, Nour Albesher, Yaseen M. Arabi, Ebrahim S. Mahmoud, Amin K. Khattab, Roaa T. Halawani, Ziab Z. Alahmadey, Jehad K. Albakri, Walaa A. Felemban, Bandar A. Suliman, Rana Hasanato, Laila Al-Awdah, Jahad Alghamdi, Deema AlZahrani, Sameera AlJohani, Hani Al-Afghani, May Alrashed, Nouf AlDhawi, Hadeel AlBardis, Sarah Alkwai, Moneera Alswailm, Faisal Almalki, Maha Albeladi, Iman Almohammed, Eman Barhoush, Anoud Albader, Salam Massadeh, Abdulaziz AlMalik, Sara Alotaibi, Bader Alghamdi, Junghyun Jung, Mohammad S. Fawzy, Yunsung Lee, Per Magnus, Lill-Iren S. Trogstad, Øyvind Helgeland, Jennifer R. Harris, Massimo Mangino, Tim D. Spector, Duncan Emma, Sandra P. Smieszek, Bartlomiej P. Przychodzen, Christos Polymeropoulos, Vasilios Polymeropoulos, Mihael H. Polymeropoulos, Israel Fernandez-Cadenas, Jordi Perez-Tur, Laia Llucià-Carol, Natalia Cullell, Elena Muiño, Jara Cárcel-Márquez, Marta L. DeDiego, Lara Lloret Iglesias, Anna M. Planas, Alex Soriano, Veronica Rico, Daiana Agüero, Josep L. Bedini, Francisco Lozano, Carlos Domingo, Veronica Robles, Francisca Ruiz-Jaén, Leonardo Márquez, Juan Gomez, Eliecer Coto, Guillermo M. Albaiceta, Marta García-Clemente, David Dalmau, Maria J. Arranz, Beatriz Dietl, Alex Serra-Llovich, Pere Soler, Roger Colobrán, Andrea Martín-Nalda, Alba Parra Martínez, David Bernardo, Silvia Rojo, Aida Fiz-López, Elisa Arribas, Paloma de la Cal-Sabater, Tomás Segura, Esther González-Villa, Gemma Serrano-Heras, Joan Martí-Fàbregas, Elena Jiménez-Xarrié, Alicia de Felipe Mimbrera, Jaime Masjuan, Sebastian García-Madrona, Anna Domínguez-Mayoral, Joan Montaner Villalonga, Paloma Menéndez-Valladares, Daniel I. Chasman, Julie E. Buring, Paul M. Ridker, Giulianini Franco, Howard D. Sesso, JoAnn E. Manson, Joseph R. Glessner, Carolina Medina-Gomez, Andre G. Uitterlinden, M. Arfan Ikram, Kati Kristiansson, Sami Koskelainen, Markus Perola, Kati Donner, Katja Kivinen, Aarno Palotie, Samuli Ripatti, Sanni Ruotsalainen, Mari Kaunisto, null FinnGen, Tomoko Nakanishi, Guillaume Butler-Laporte, Vincenzo Forgetta, David R. Morrison, Biswarup Ghosh, Laetitia Laurent, Alexandre Belisle, Danielle Henry, Tala Abdullah, Olumide Adeleye, Noor Mamlouk, Nofar Kimchi, Zaman Afrasiabi, Nardin Rezk Branka Vulesevic, Meriem Bouab, Charlotte Guzman, Louis Petitjean, Chris Tselios, Xiaoqing Xue, Erwin Schurr, Jonathan Afilalo, Marc Afilalo, Maureen Oliveira, Bluma Brenner, Pierre Lepage, Jiannis Ragoussis, Daniel Auld, Nathalie Brassard, Madeleine Durand, Michaël Chassé, Daniel E. Kaufmann, G. Mark Lathrop, Vincent Mooser, J. Brent Richards, Rui Li, Darin Adra, Souad Rahmouni, Michel Georges, Michel Moutschen, Benoit Misset, Gilles Darcis, Julien Guiot, Julien Guntz, Samira Azarzar, Stéphanie Gofflot, Yves Beguin, Sabine Claassen, Olivier Malaise, Pascale Huynen, Christelle Meuris, Marie Thys, Jessica Jacques, Philippe Léonard, Frederic Frippiat, Jean-Baptiste Giot, Anne-Sophie Sauvage, Christian Von Frenckell, Yasmine Belhaj, Bernard Lambermont, Sara Pigazzini, Lindokuhle Nkambule, Michelle Daya, Jonathan Shortt, Nicholas Rafaels, Stephen J. Wicks, Kristy Crooks, Kathleen C. Barnes, Christopher R. Gignoux, Sameer Chavan, Triin Laisk, Kristi Läll, Maarja Lepamets, Reedik Mägi, Tõnu Esko, Ene Reimann, Lili Milani, Helene Alavere, Kristjan Metsalu, Mairo Puusepp, Andres Metspalu, Paul Naaber, Edward Laane, Jaana Pesukova, Pärt Peterson, Kai Kisand, Jekaterina Tabri, Raili Allos, Kati Hensen, Joel Starkopf, Inge Ringmets, Anu Tamm, Anne Kallaste, Pierre-Yves Bochud, Carlo Rivolta, Stéphanie Bibert, Mathieu Quinodoz, Dhryata Kamdar, Noémie Boillat, Semira Gonseth Nussle, Werner Albrich, Noémie Suh, Dionysios Neofytos, Véronique Erard, Cathy Voide, null FHoGID, null RegCOVID, null P-PredictUs, null SeroCOVID, null CRiPSI, Rafael de Cid, Iván Galván-Femenía, Natalia Blay, Anna Carreras, Beatriz Cortés, Xavier Farré, Lauro Sumoy, Victor Moreno, Josep Maria Mercader, Marta Guindo-Martinez, David Torrents, Manolis Kogevinas, Judith Garcia-Aymerich, Gemma Castaño-Vinyals, Carlota Dobaño, Alessandra Renieri, Francesca Mari, Chiara Fallerini, Sergio Daga, Elisa Benetti, Margherita Baldassarri, Francesca Fava, Elisa Frullanti, Floriana Valentino, Gabriella Doddato, Annarita Giliberti, Rossella Tita, Sara Amitrano, Mirella Bruttini, Susanna Croci, Ilaria Meloni, Maria Antonietta Mencarelli, Caterina Lo Rizzo, Anna Maria Pinto, Giada Beligni, Andrea Tommasi, Laura Di Sarno, Maria Palmieri, Miriam Lucia Carriero, Diana Alaverdian, Stefano Busani, Raffaele Bruno, Marco Vecchia, Mary Ann Belli, Nicola Picchiotti, Maurizio Sanarico, Marco Gori, Simone Furini, Stefania Mantovani, Serena Ludovisi, Mario Umberto Mondelli, Francesco Castelli, Eugenia Quiros-Roldan, Melania Degli Antoni, Isabella Zanella, Massimo Vaghi, Stefano Rusconi, Matteo Siano, Francesca Montagnani, Arianna Emiliozzi, Massimiliano Fabbiani, Barbara Rossetti, Elena Bargagli, Laura Bergantini, Miriana D’Alessandro, Paolo Cameli, David Bennett, Federico Anedda, Simona Marcantonio, Sabino Scolletta, Federico Franchi, Maria Antonietta Mazzei, Susanna Guerrini, Edoardo Conticini, Luca Cantarini, Bruno Frediani, Danilo Tacconi, Chiara Spertilli, Marco Feri, Alice Donati, Raffaele Scala, Luca Guidelli, Genni Spargi, Marta Corridi, Cesira Nencioni, Leonardo Croci, Maria Bandini, Gian Piero Caldarelli, Paolo Piacentini, Elena Desanctis, Silvia Cappelli, Anna Canaccini, Agnese Verzuri, Valentina Anemoli, Agostino Ognibene, Alessandro Pancrazzi, Maria Lorubbio, Antonella D’Arminio Monforte, Federica Gaia Miraglia, Massimo Girardis, Sophie Venturelli, Andrea Cossarizza, Andrea Antinori, Alessandra Vergori, Arianna Gabrieli, Agostino Riva, Daniela Francisci, Elisabetta Schiaroli, Francesco Paciosi, Pier Giorgio Scotton, Francesca Andretta, Sandro Panese, Renzo Scaggiante, Francesca Gatti, Saverio Giuseppe Parisi, Stefano Baratti, Matteo Della Monica, Carmelo Piscopo, Mario Capasso, Roberta Russo, Immacolata Andolfo, Achille Iolascon, Giuseppe Fiorentino, Massimo Carella, Marco Castori, Giuseppe Merla, Gabriella Maria Squeo, Filippo Aucella, Pamela Raggi, Carmen Marciano, Rita Perna, Matteo Bassetti, Antonio Di Biagio, Maurizio Sanguinetti, Luca Masucci, Serafina Valente, Marco Mandalà, Alessia Giorli, Lorenzo Salerni, Patrizia Zucchi, Pierpaolo Parravicini, Elisabetta Menatti, Tullio Trotta, Ferdinando Giannattasio, Gabriella Coiro, Fabio Lena, Domenico A. Coviello, Cristina Mussini, Enrico Martinelli, Sandro Mancarella, Luisa Tavecchia, Lia Crotti, Chiara Gabbi, Marco Rizzi, Franco Maggiolo, Diego Ripamonti, Tiziana Bachetti, Maria Teresa La Rovere, Simona Sarzi-Braga, Maurizio Bussotti, Stefano Ceri, Pietro Pinoli, Francesco Raimondi, Filippo Biscarini, Alessandra Stella, Kristina Zguro, Katia Capitani, Claudia Suardi, Simona Dei, Gianfranco Parati, Sabrina Ravaglia, Rosangela Artuso, Giordano Bottà, Paolo Di Domenico, Ilaria Rancan, Antonio Perrella Francesco Bianchi, Davide Romani, Paola Bergomi, Emanuele Catena, Riccardo Colombo, Marco Tanfoni, Antonella Vincenti, Claudio Ferri, Davide Grassi, Gloria Pessina, Mario Tumbarello, Massimo Di Pietro, Ravaglia Sabrina, Sauro Luchi, Chiara Barbieri, Donatella Acquilini, Elena Andreucci, Francesco Vladimiro Segala, Giusy Tiseo, Marco Falcone, Mirjam Lista, Monica Poscente, Oreste De Vivo, Paola Petrocelli, Alessandra Guarnaccia, Silvia Baroni, Albert V. Smith, Andrew P. Boughton, Kevin W. Li, Jonathon LeFaive, Aubrey Annis, Anne E. Justice, Tooraj Mirshahi, Geetha Chittoor, Navya Shilpa Josyula, Jack A. Kosmicki, Manuel A.R. Ferreira, Joseph B. Leader, Dave J. Carey, Matthew C. Gass, Julie E. Horowitz, Michael N. Cantor, Ashish Yadav, Aris Baras, Goncalo R. Abecasis, David A. van Heel, Karen A. Hunt, Dan Mason, Qin Qin Huang, Sarah Finer, null Genes & Health Research Team, Bhavi Trivedi, Christopher J. Griffiths, Hilary C. Martin, John Wright, Richard C. Trembath, Nicole Soranzo, Jing Hua Zhao, Adam S. Butterworth, John Danesh, Emanuele Di Angelantonio, Lude Franke Marike Boezen, Patrick Deelen, Annique Claringbould, Esteban Lopera, Robert Warmerdam, Judith.M. Vonk, Irene van Blokland, Pauline Lanting, Anil P.S. Ori, Brooke Wolford Sebastian Zöllner, Jiongming Wang, Andrew Beck, Gina Peloso, Yuk-Lam Ho, Yan V. Sun, Jennifer E. Huffman, Christopher J. O’Donnell, Kelly Cho, Phil Tsao, J. Michael Gaziano, Michel (M.G.) Nivard, Eco (E.J.C.) de geus, Meike Bartels, Jouke Jan Hottenga, Scott T. Weiss, Elizabeth W. Karlson, Jordan W. Smoller, Robert C. Green, Yen-Chen Anne Feng, Josep Mercader, Shawn N. Murphy, James B. Meigs, Ann E. Woolley, Emma F. Perez, Daniel Rader, Anurag Verma, Marylyn D. Ritchie, Binglan Li, Shefali S. Verma, Anastasia Lucas, Yuki Bradford, Hugo Zeberg, Robert Frithiof, Michael Hultström, Miklos Lipcsey, Lindo Nkambul, Nicolas Tardif, Olav Rooyackers, Jonathan Grip, Tomislav Maricic, Konrad J. Karczewski, Elizabeth G. Atkinson, Kristin Tsuo, Nikolas Baya, Patrick Turley, Rahul Gupta, Shawneequa Callier, Raymond K. Walters, Duncan S. Palmer, Gopal Sarma, Nathan Cheng, Wenhan Lu, Sam Bryant, Claire Churchhouse, Caroline Cusick, Jacqueline I. Goldstein, Daniel King, Cotton Seed, Hilary Finucane, Alicia R. Martin, F. Kyle Satterstrom, Daniel J. Wilson, Jacob Armstrong, Justine K. Rudkin, Gavin Band, Sarah G. Earle, Shang-Kuan Lin, Nicolas Arning, Derrick W. Crook, David H. Wyllie, Anne Marie O’Connell, Chris C.A. Spencer, Nils Koelling, Mark J. Caulfield, Richard H. Scott, Tom Fowler, Loukas Moutsianas, Athanasios Kousathanas, Dorota Pasko, Susan Walker, Augusto Rendon, Alex Stuckey, Christopher A. Odhams, Daniel Rhodes, Georgia Chan, Prabhu Arumugam, Catherine A. Ball, Eurie L. Hong, Kristin Rand, Ahna Girshick, Harendra Guturu, Asher Haug Baltzell, Genevieve Roberts, Danny Park, Marie Coignet, Shannon McCurdy, Spencer Knight, Raghavendran Partha, Brooke Rhead, Miao Zhang, Nathan Berkowitz, Michael Gaddis, Keith Noto, Luong Ruiz, Milos Pavlovic, Laura G. Sloofman, Alexander W. Charney, Noam D. Beckmann, Eric E. Schadt, Daniel M. Jordan, Ryan C. Thompson, Kyle Gettler, Noura S. Abul-Husn, Steven Ascolillo, Joseph D. Buxbaum, Kumardeep Chaudhary, Judy H. Cho, Yuval Itan, Eimear E. Kenny, Gillian M. Belbin, Stuart C. Sealfon, Robert P. Sebra, Irene Salib, Brett L. Collins, Tess Levy, Bari Britvan, Katherine Keller, Lara Tang, Michael Peruggia, Liam L. Hiester, Kristi Niblo, Alexandra Aksentijevich, Alexander Labkowsky, Avromie Karp, Menachem Zlatopolsky, Michael Preuss, Ruth J.F. Loos, Girish N. Nadkarni, Ron Do, Clive Hoggart, Sam Choi, Slayton J. Underwood, Paul O’Reilly, Laura M. Huckins, Marissa Zyndorf
Publikováno v:
Cell Reports
Cell reports, 37(7):110020. Cell Press
Cell Reports, Vol 37, Iss 7, Pp 110020-(2021)
Cell reports, vol 37, iss 7
Cell reports, 37(7):110020. Cell Press
Cell Reports, Vol 37, Iss 7, Pp 110020-(2021)
Cell reports, vol 37, iss 7
Variability in SARS-CoV-2 susceptibility and COVID-19 disease severity between individuals is partly due to genetic factors. Here, we identify 4 genomic loci with suggestive associations for SARS-CoV-2 susceptibility and 19 for COVID-19 disease sever
Autor:
Paul Farrant, Mark Goodfield, Catherine H. Smith, V. Jolliffe, Gregory Parkins, Caroline Champagne, Lu Liu, Nigel Burrows, A. S. Bryden, Kristie Wood, Anton B. Alexandroff, Irene Man, Alka Saxena, Su M. Lwin, Iaisha Ali, Catherine M. Stefanato, Kapil Bhargava, Sang Hyuck Lee, Melanie Page, Xavier Estivill, Tim D. Spector, Carsten Flohr, Susan Holmes, David de Berker, A. E. Macbeth, Ncoza C. Dlova, David Baudry, Jake Saklatvala, Nerea Ormaechea Perez, Archana Rao, David A. Fenton, Martin S Wade, Cedric Charles Banfield, Jennifer Jones, Evangelos A A Christou, Ravinder Atkar, Gregory A Michelotti, Sergio Vano-Galvan, Seth D. Seegobin, Jane Setterfield, Jonathan Barker, Chrysanthi Ainali, Christos Tziotzios, Charles Curtis, Rashida Pramanik, Matthew Harries, Girish K Patel, Niall Kirkpatrick, Venu Pullabhatla, Fiona Cunningham, Nick Dand, Hywel L Cooper, Rodney Sinclair, Keith Armstrong, Emanuele de Rinaldis, Andrew J. G. McDonagh, M R Kaur, Fiona Lewis, Michael A. Simpson, John A. McGrath, Charles E. Mitchell, Nicola Cooke, Fiona M. Watt, Alexandros Onoufriadis, Michael R. Ardern-Jones, Tee-Wei Siah, Ioulios Palamaras, Ana María Molina-Ruiz, Megan Mowbray, A. Takwale, Andrew G. Messenger, Giles Dunnill, Christos Petridis, Shyamal Wahie
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Nature Communications
Tziotzios, C, Petridis, C, Dand, N, Ainali, C, Saklatvala, J R, Pullabhatla, V, Onoufriadis, A, Pramanik, R, Baudry, D, Lee, S H, Wood, K, Liu, L, Seegobin, S, Michelotti, G A, Lwin, S M, Christou, E A A, Curtis, C J, de Rinaldis, E, Saxena, A, Holmes, S, Harries, M, Palamaras, I, Cunningham, F, Parkins, G, Kaur, M, Farrant, P, McDonagh, A, Messenger, A, Jones, J, Jolliffe, V, Ali, I, Ardern-Jones, M, Mitchell, C, Burrows, N, Atkar, R, Banfield, C, Alexandroff, A, Champagne, C, Cooper, H L, Vañó-Galván, S, Molina-Ruiz, A M, Perez, N O, Patel, G K, Macbeth, A, Page, M, Bryden, A, Mowbray, M, Wahie, S, Armstrong, K, Cooke, N, Goodfield, M, Man, I, de Berker, D, Dunnill, G, Takwale, A, Rao, A, Siah, T-W, Sinclair, R, Wade, M S, Dlova, N C, Setterfield, J, Lewis, F, Bhargava, K, Kirkpatrick, N, Estivill, X, Stefanato, C M, Flohr, C, Spector, T, Watt, F M, Smith, C H, Barker, J N, Fenton, D A, Simpson, M A & McGrath, J A 2019, ' Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02 ', Nature Communications, vol. 10, no. 1, 1150 . https://doi.org/10.1038/s41467-019-09117-w
Tziotzios, C, Petridis, C, Dand, N, Ainali, C, Saklatvala, J R, Pullabhatla, V, Onoufriadis, A, Pramanik, R, Baudry, D, Lee, S H, Wood, K, Liu, L, Seegobin, S, Michelotti, G A, Lwin, S M, Christou, E A A, Curtis, C J, de Rinaldis, E, Saxena, A, Holmes, S, Harries, M, Palamaras, I, Cunningham, F, Parkins, G, Kaur, M, Farrant, P, McDonagh, A, Messenger, A, Jones, J, Jolliffe, V, Ali, I, Ardern-Jones, M, Mitchell, C, Burrows, N, Atkar, R, Banfield, C, Alexandroff, A, Champagne, C, Cooper, H L, Vañó-Galván, S, Molina-Ruiz, A M, Perez, N O, Patel, G K, Macbeth, A, Page, M, Bryden, A, Mowbray, M, Wahie, S, Armstrong, K, Cooke, N, Goodfield, M, Man, I, de Berker, D, Dunnill, G, Takwale, A, Rao, A, Siah, T W, Sinclair, R, Wade, M S, Dlova, N C, Setterfield, J, Lewis, F, Bhargava, K, Kirkpatrick, N, Estivill, X, Stefanato, C M, Flohr, C, Spector, T, Watt, F M, Smith, C H, Barker, J N, Fenton, D A, Simpson, M A & McGrath, J A 2019, ' Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02 ', Nature Communications, vol. 10, no. 1, 1150 . https://doi.org/10.1038/s41467-019-09117-w
Nature Communications
Tziotzios, C, Petridis, C, Dand, N, Ainali, C, Saklatvala, J R, Pullabhatla, V, Onoufriadis, A, Pramanik, R, Baudry, D, Lee, S H, Wood, K, Liu, L, Seegobin, S, Michelotti, G A, Lwin, S M, Christou, E A A, Curtis, C J, de Rinaldis, E, Saxena, A, Holmes, S, Harries, M, Palamaras, I, Cunningham, F, Parkins, G, Kaur, M, Farrant, P, McDonagh, A, Messenger, A, Jones, J, Jolliffe, V, Ali, I, Ardern-Jones, M, Mitchell, C, Burrows, N, Atkar, R, Banfield, C, Alexandroff, A, Champagne, C, Cooper, H L, Vañó-Galván, S, Molina-Ruiz, A M, Perez, N O, Patel, G K, Macbeth, A, Page, M, Bryden, A, Mowbray, M, Wahie, S, Armstrong, K, Cooke, N, Goodfield, M, Man, I, de Berker, D, Dunnill, G, Takwale, A, Rao, A, Siah, T-W, Sinclair, R, Wade, M S, Dlova, N C, Setterfield, J, Lewis, F, Bhargava, K, Kirkpatrick, N, Estivill, X, Stefanato, C M, Flohr, C, Spector, T, Watt, F M, Smith, C H, Barker, J N, Fenton, D A, Simpson, M A & McGrath, J A 2019, ' Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02 ', Nature Communications, vol. 10, no. 1, 1150 . https://doi.org/10.1038/s41467-019-09117-w
Tziotzios, C, Petridis, C, Dand, N, Ainali, C, Saklatvala, J R, Pullabhatla, V, Onoufriadis, A, Pramanik, R, Baudry, D, Lee, S H, Wood, K, Liu, L, Seegobin, S, Michelotti, G A, Lwin, S M, Christou, E A A, Curtis, C J, de Rinaldis, E, Saxena, A, Holmes, S, Harries, M, Palamaras, I, Cunningham, F, Parkins, G, Kaur, M, Farrant, P, McDonagh, A, Messenger, A, Jones, J, Jolliffe, V, Ali, I, Ardern-Jones, M, Mitchell, C, Burrows, N, Atkar, R, Banfield, C, Alexandroff, A, Champagne, C, Cooper, H L, Vañó-Galván, S, Molina-Ruiz, A M, Perez, N O, Patel, G K, Macbeth, A, Page, M, Bryden, A, Mowbray, M, Wahie, S, Armstrong, K, Cooke, N, Goodfield, M, Man, I, de Berker, D, Dunnill, G, Takwale, A, Rao, A, Siah, T W, Sinclair, R, Wade, M S, Dlova, N C, Setterfield, J, Lewis, F, Bhargava, K, Kirkpatrick, N, Estivill, X, Stefanato, C M, Flohr, C, Spector, T, Watt, F M, Smith, C H, Barker, J N, Fenton, D A, Simpson, M A & McGrath, J A 2019, ' Genome-wide association study in frontal fibrosing alopecia identifies four susceptibility loci including HLA-B*07:02 ', Nature Communications, vol. 10, no. 1, 1150 . https://doi.org/10.1038/s41467-019-09117-w
Frontal fibrosing alopecia (FFA) is a recently described inflammatory and scarring type of hair loss affecting almost exclusively women. Despite a dramatic recent increase in incidence the aetiopathogenesis of FFA remains unknown. We undertake genome
Autor:
Cindy G. Boer, Konstantinos Hatzikotoulas, Lorraine Southam, Lilja Stefánsdóttir, Yanfei Zhang, Rodrigo Coutinho de Almeida, Tian T. Wu, Jie Zheng, April Hartley, Maris Teder-Laving, Anne Heidi Skogholt, Chikashi Terao, Eleni Zengini, George Alexiadis, Andrei Barysenka, Gyda Bjornsdottir, Maiken E. Gabrielsen, Arthur Gilly, Thorvaldur Ingvarsson, Marianne B. Johnsen, Helgi Jonsson, Margreet Kloppenburg, Almut Luetge, Sigrun H. Lund, Reedik Mägi, Massimo Mangino, Rob R.G.H.H. Nelissen, Manu Shivakumar, Julia Steinberg, Hiroshi Takuwa, Laurent F. Thomas, Margo Tuerlings, George C. Babis, Jason Pui Yin Cheung, Jae Hee Kang, Peter Kraft, Steven A. Lietman, Dino Samartzis, P. Eline Slagboom, Kari Stefansson, Unnur Thorsteinsdottir, Jonathan H. Tobias, André G. Uitterlinden, Bendik Winsvold, John-Anker Zwart, George Davey Smith, Pak Chung Sham, Gudmar Thorleifsson, Tom R. Gaunt, Andrew P. Morris, Ana M. Valdes, Aspasia Tsezou, Kathryn S.E. Cheah, Shiro Ikegawa, Kristian Hveem, Tõnu Esko, J. Mark Wilkinson, Ingrid Meulenbelt, Ming Ta Michael Lee, Joyce B.J. van Meurs, Unnur Styrkársdóttir, Eleftheria Zeggini, John Loughlin, Nigel Arden, Fraser Birrell, Andrew Carr, Panos Deloukas, Michael Doherty, Andrew W. McCaskie, William E.R. Ollier, Ashok Rai, Stuart H. Ralston, Tim D. Spector, Gillian A. Wallis, Amy E. Martinsen, Cristen Willer, Egil Andreas Fors, Ingunn Mundal, Knut Hagen, Kristian Bernhard Nilsen, Marie Udnesseter Lie, Sigrid Børte, Ben Brumpton, Jonas Bille Nielsen, Lars G. Fritsche, Wei Zhou, Ingrid Heuch, Kjersti Storheim, Evangelos Tyrpenou, Athanasios Koukakis, Dimitrios Chytas, Dimitrios Stergios Evangelopoulos, Chronopoulos Efstathios, Spiros Pneumaticos, Vasileios S. Nikolaou, Konstantinos Malizos, Lydia Anastasopoulou, Goncalo Abecasis, Aris Baras, Michael Cantor, Giovanni Coppola, Andrew Deubler, Aris Economides, Luca A. Lotta, John D. Overton, Jeffrey G. Reid, Alan Shuldiner, Katia Karalis, Katherine Siminovitch, Christina Beechert, Caitlin Forsythe, Erin D. Fuller, Zhenhua Gu, Michael Lattari, Alexander Lopez, Thomas D. Schleicher, Maria Sotiropoulos Padilla, Louis Widom, Sarah E. Wolf, Manasi Pradhan, Kia Manoochehri, Xiaodong Bai, Suganthi Balasubramanian, Boris Boutkov, Gisu Eom, Lukas Habegger, Alicia Hawes, Olga Krasheninina, Rouel Lanche, Adam J. Mansfield, Evan K. Maxwell, Mona Nafde, Sean O’Keeffe, Max Orelus, Razvan Panea, Tommy Polanco, Ayesha Rasool, William Salerno, Jeffrey C. Staples, Dadong Li, Deepika Sharma, Ilanjana Banerjee, Jonas Bovijn, Adam Locke, Niek Verweij, Mary Haas, George Hindy, Tanima De, Parsa Akbari, Olukayode Sosina, Manuel A.R. Ferreira, Marcus B. Jones, Jason Mighty, Michelle G. LeBlanc, Lyndon J. Mitnaul
Publikováno v:
Cell
Cell 184, 4784-4818.e17 (2021)
Cell, 184(18), 4784-4818. CELL PRESS
Cell, 184(18), 4784-4818.e17. Cell Press
Boer, C G, Hatzikotoulas, K, Southam, L, Stefansdottir, L, Zhang, Y, Coutinho de Almeida, R, wu, T T, Zhang, J, Hartley, A E, Teder-Laving, M, Skogholt, A H, Terao, C, Zengini, E, Alexiadis, G, Barysenka, A, Bjornsdottir, G, Gabrielsen, M, Gilly, A, Ingvarsson, T, Johnsen, M B, Jonsson, H, Kloppenburg, M, Luetge, A, Lund, S H, Mägi, R, Mangino, M, Nelissen, R, Shivakumar, M, Steinberg, J, Takuwa, H, Thomas, L, Tuerlings, M, Babis, G C, Pui Yin Cheung, J, Kang, J H, Kraft, P, Lietman, S A, Samartzis, D, Slagboom, E, Stefansson, K, Thorsteinsdottir, U, Tobias, J H, Uitterlinden, A G, Winsvold, B S, Zwart, J-A, Davey Smith, G, Sham, P C, Thorleifsson, G, Gaunt, T R, Morris, A, Valdes, A M, Tsezou, A, S.E. Cheah, K, Ikegawa, S, Hveem, K, Esko, T, Wilkinson, J M, Meulenbelt, I, Ta Michael Lee, M, van Meurs, J B J, Styrkarsdottir, U & Zeggini, E 2021, ' Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations ', Cell, vol. 184, no. 18, pp. 4784-4818.e17 . https://doi.org/10.1016/j.cell.2021.07.038
Cell 184, 4784-4818.e17 (2021)
Cell, 184(18), 4784-4818. CELL PRESS
Cell, 184(18), 4784-4818.e17. Cell Press
Boer, C G, Hatzikotoulas, K, Southam, L, Stefansdottir, L, Zhang, Y, Coutinho de Almeida, R, wu, T T, Zhang, J, Hartley, A E, Teder-Laving, M, Skogholt, A H, Terao, C, Zengini, E, Alexiadis, G, Barysenka, A, Bjornsdottir, G, Gabrielsen, M, Gilly, A, Ingvarsson, T, Johnsen, M B, Jonsson, H, Kloppenburg, M, Luetge, A, Lund, S H, Mägi, R, Mangino, M, Nelissen, R, Shivakumar, M, Steinberg, J, Takuwa, H, Thomas, L, Tuerlings, M, Babis, G C, Pui Yin Cheung, J, Kang, J H, Kraft, P, Lietman, S A, Samartzis, D, Slagboom, E, Stefansson, K, Thorsteinsdottir, U, Tobias, J H, Uitterlinden, A G, Winsvold, B S, Zwart, J-A, Davey Smith, G, Sham, P C, Thorleifsson, G, Gaunt, T R, Morris, A, Valdes, A M, Tsezou, A, S.E. Cheah, K, Ikegawa, S, Hveem, K, Esko, T, Wilkinson, J M, Meulenbelt, I, Ta Michael Lee, M, van Meurs, J B J, Styrkarsdottir, U & Zeggini, E 2021, ' Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations ', Cell, vol. 184, no. 18, pp. 4784-4818.e17 . https://doi.org/10.1016/j.cell.2021.07.038
Summary Osteoarthritis affects over 300 million people worldwide. Here, we conduct a genome-wide association study meta-analysis across 826,690 individuals (177,517 with osteoarthritis) and identify 100 independently associated risk variants across 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2107ed7b2af740104437a8ef894bb702
http://hdl.handle.net/10852/89014
http://hdl.handle.net/10852/89014
Autor:
Kai-How Farh, Caleb Webber, Albert Hofman, George McMahon, Nicholas G. Martin, Paul M. Ridker, Lynn Cherkas, Mart Kals, Dorret I. Boomsma, George Davey Smith, Verneri Anttila, Tune H. Pers, Bertram Müller-Myhsok, Ville Artto, Benjamin M. Neale, Ester Cuenca-León, Anine H. Stam, Christopher Sivert Nielsen, Hieab H.H. Adams, Guntram Borck, Andres Metspalu, Maria Gudlaug Hrafnsdottir, Martin Dichgans, Reedik Mägi, Hailiang Huang, Daniel I. Chasman, Elizabeth Loehrer, John-Anker Zwart, Thomas Meitinger, Markus Färkkilä, Cornelia M. van Duijn, Arn M. J. M. van den Maagdenberg, Evie Stergiakouli, Johan G. Eriksson, Kauko Heikkilä, Hreinn Stefansson, Nicholas A. Furlotte, Minna Männikkö, Nicholas Eriksson, Jaakko Kaprio, David P. Strachan, Juho Wedenoja, Zameel M. Cader, Scott G. Gordon, Brenda W.J.H. Penninx, Linda M. Pedersen, Olli T. Raitakari, Phil Lee, André G. Uitterlinden, Ann-Louise Esserlind, Tobias Kurth, Arpo Aromaa, Priit Palta, Jes Olesen, Audun Stubhaug, Antti-Pekka Sarin, Andres Ingason, Stefan Schreiber, Salli Vepsäläinen, Hartmut Göbel, Kalle Pärn, Jouke-Jan Hottenga, Kari Stefansson, Bendik S. Winsvold, Markku Koiranen, Tim D. Spector, Evelin Mihailov, Mikko Muona, Marjo-Riitta Järvelin, Cynthia Sandor, Anne Francke Christensen, Lude Franke, Grant W. Montgomery, Tobias Freilinger, Caroline Ran, Thomas Werge, Maija Wessman, David A. Hinds, Lannie Ligthart, Terho Lehtimäki, Lili Milani, Mari A. Kaunisto, Lydia Quaye, Andrea Carmine Belin, Eija Hamalainen, M. Arfan Ikram, Veikko Salomaa, Mark J. Daly, Dale R. Nyholt, Pamela A. F. Madden, Andrew C. Heath, Tõnu Esko, Rainer Malik, Gisela M. Terwindt, Mitja I. Kurki, Aarno Palotie, Thomas Hansen, Padhraig Gormley, Michel D. Ferrari, Susan M. Ring, Julie E. Buring, Christian Kubisch, Mikko Kallela, Andrea Byrnes, Stacy Steinberg, Jie Huang, Markus Schürks
Publikováno v:
Gormley, P, Anttila, V, Winsvold, B S, Palta, P, Esko, T, Pers, T H, Farh, K H, Cuenca-Leon, E, Muona, M, Furlotte, N A, Kurth, T, Ingason, A, McMahon, G, Ligthart, L, Terwindt, G M, Kallela, M, Freilinger, T, Ran, C, Gordon, S G, Stam, A H, Steinberg, S, Borck, G, Koiranen, M, Quaye, L, Adams, H H H, Lehtimäki, T, Sarin, A P, Wedenoja, J, Hinds, D A, Buring, J E, Schürks, M, Ridker, P M, Gudlaug Hrafnsdottir, M, Stefansson, H, Ring, S M, Hottenga, J J, Penninx, B W J H, Färkkilä, M, Artto, V, Kaunisto, M A, Vepsäläinen, S, Malik, R, Heath, A C, Madden, P A F, Martin, N G, Montgomery, G W, Kurki, M I, Kals, M, Mägi, R, Pärn, K, Hämaläinen, E, Huang, H, Byrnes, A E, Franke, L, Huang, J, Stergiakouli, E, Lee, P H, Sandor, C, Webber, C, Cader, Z, Müller-Myhsok, B, Schreiber, S, Meitinger, T, Eriksson, J G, Salomaa, V, Heikkilä, K, Loehrer, A G, Uitterlinden, A G, Hofman, A, van Duijn, C M, Cherkas, L, Pedersen, L, Stubhaug, A, Nielsen, C S, Männikkö, M, Mihailov, E, Milani, L, Göbel, H, Esserlind, A L, Francke Christensen, A, Folkmann Hansen, T, Werge, T, Kaprio, J, Aromaa, A, Raitakari, O, Ikram, M A, Spector, T D, Järvelin, M R, Metspalu, A, Kubisch, C, Strachan, D P, Ferrari, M D, Belin, A C, Dichgans, M, Wessman, M, van den Maagdenberg, A M J M, Zwart, J A, Boomsma, D I, Davey Smith, G, Stefansson, K, Eriksson, N, Daly, M J, Neale, B M, Olesen, J, Chasman, D I, Nyholt, DR, Palotie, A & Posthuma, D 2016, ' Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine ', Nature Genetics, vol. 48, no. 8, pp. 856-866 . https://doi.org/10.1038/ng.3598
Nature Genetics
Nature Genetics, 48(8), 856
Nature Genetics, 48(8), 856-869. Nature Publishing Group
Gormley, P, Anttila, V, Winsvold, B S, Palta, P, Esko, T, Pers, T H, Farh, K-H, Cuenca-Leon, E, Muona, M, Furlotte, N A, Kurth, T, Ingason, A, McMahon, G, Ligthart, L, Terwindt, G M, Kallela, M, Freilinger, T M, Ran, C, Gordon, S G, Stam, A H, Steinberg, S, Borck, G, Koiranen, M, Quaye, L, Adams, H H H, Lehtimaki, T, Sarin, A-P, Wedenoja, J, Hinds, D A, Buring, J E, Schurks, M, Ridker, P M, Hrafnsdottir, M G, Stefansson, H, Ring, S M, Hottenga, J-J, Penninx, B W J H, Farkkila, M, Artto, V, Kaunisto, M, Vepsalainen, S, Malik, R, Heath, A C, Madden, P A F, Martin, N G, Montgomery, G W, Kurki, M I, Kals, M, Magi, R, Parn, K, Hamalainen, E, Huang, H, Byrnes, A E, Franke, L, Huang, J, Stergiakouli, E, Lee, P H, Sandor, C, Webber, C, Cader, Z, Muller-Myhsok, B, Schreiber, S, Meitinger, T, Eriksson, J G, Salomaa, V, Heikkila, K, Loehrer, E, Uitterlinden, A G, Hofman, A, van Duijn, C M, Cherkas, L, Pedersen, L M, Stubhaug, A, Nielsen, C S, Mannikko, M, Mihailov, E, Milani, L, Gobel, H, Esserlind, A-L, Christensen, A F, Hansen, T F, Werge, T, Kaprio, J, Aromaa, A J, Raitakari, O, Ikram, M A, Spector, T, Jarvelin, M-R, Metspalu, A, Kubisch, C, Strachan, D P, Ferrari, M D, Belin, A C, Dichgans, M, Wessman, M, van den Maagdenberg, A M J M, Zwart, J-A, Boomsma, D I, Smith, G D, Stefansson, K, Eriksson, N, Daly, M J, Neale, B M, Olesen, J, Chasman, D I, Nyholt, D R, Palotie, A & Posthuma, D 2016, ' Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine ', Nature Genetics, vol. 48, no. 8, pp. 856-866 . https://doi.org/10.1038/ng.3598
Nature Genetics, 48(8), 856-866. Nature Publishing Group
Dipòsit Digital de la UB
Universidad de Barcelona
Nat. Genet. 48, 856-866 (2016)
Gormley, P, Anttila, V, Winsvold, B S, Palta, P, Esko, T, Pers, T H, Farh, K-H, Cuenca-Leon, E, Muona, M, Furlotte, N A, Kurth, T, Ingason, A, McMahon, G, Ligthart, L, Terwindt, G M, Kallela, M, Freilinger, T M, Ran, C, Gordon, S G, Stam, A H, Steinberg, S, Borck, G, Koiranen, M, Quaye, L, Adams, H H H, Lehtimäki, T, Sarin, A-P, Wedenoja, J, Hinds, D A, Buring, J E, Schürks, M, Ridker, P M, Hrafnsdottir, M G, Stefansson, H, Ring, S M, Hottenga, J-J, Penninx, B W J H, Färkkilä, M, Artto, V, Kaunisto, M, Vepsäläinen, S, Malik, R, Heath, A C, Madden, P A F, Martin, N G, Montgomery, G W, Kurki, M I, Kals, M, Stergiakouli, E, Smith, G D 2016, ' Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine ', Nature Genetics, vol. 48, no. 8, pp. 856-66 . https://doi.org/10.1038/ng.3598
Nature Genetics
Nature Genetics, 48(8), 856
Nature Genetics, 48(8), 856-869. Nature Publishing Group
Gormley, P, Anttila, V, Winsvold, B S, Palta, P, Esko, T, Pers, T H, Farh, K-H, Cuenca-Leon, E, Muona, M, Furlotte, N A, Kurth, T, Ingason, A, McMahon, G, Ligthart, L, Terwindt, G M, Kallela, M, Freilinger, T M, Ran, C, Gordon, S G, Stam, A H, Steinberg, S, Borck, G, Koiranen, M, Quaye, L, Adams, H H H, Lehtimaki, T, Sarin, A-P, Wedenoja, J, Hinds, D A, Buring, J E, Schurks, M, Ridker, P M, Hrafnsdottir, M G, Stefansson, H, Ring, S M, Hottenga, J-J, Penninx, B W J H, Farkkila, M, Artto, V, Kaunisto, M, Vepsalainen, S, Malik, R, Heath, A C, Madden, P A F, Martin, N G, Montgomery, G W, Kurki, M I, Kals, M, Magi, R, Parn, K, Hamalainen, E, Huang, H, Byrnes, A E, Franke, L, Huang, J, Stergiakouli, E, Lee, P H, Sandor, C, Webber, C, Cader, Z, Muller-Myhsok, B, Schreiber, S, Meitinger, T, Eriksson, J G, Salomaa, V, Heikkila, K, Loehrer, E, Uitterlinden, A G, Hofman, A, van Duijn, C M, Cherkas, L, Pedersen, L M, Stubhaug, A, Nielsen, C S, Mannikko, M, Mihailov, E, Milani, L, Gobel, H, Esserlind, A-L, Christensen, A F, Hansen, T F, Werge, T, Kaprio, J, Aromaa, A J, Raitakari, O, Ikram, M A, Spector, T, Jarvelin, M-R, Metspalu, A, Kubisch, C, Strachan, D P, Ferrari, M D, Belin, A C, Dichgans, M, Wessman, M, van den Maagdenberg, A M J M, Zwart, J-A, Boomsma, D I, Smith, G D, Stefansson, K, Eriksson, N, Daly, M J, Neale, B M, Olesen, J, Chasman, D I, Nyholt, D R, Palotie, A & Posthuma, D 2016, ' Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine ', Nature Genetics, vol. 48, no. 8, pp. 856-866 . https://doi.org/10.1038/ng.3598
Nature Genetics, 48(8), 856-866. Nature Publishing Group
Dipòsit Digital de la UB
Universidad de Barcelona
Nat. Genet. 48, 856-866 (2016)
Gormley, P, Anttila, V, Winsvold, B S, Palta, P, Esko, T, Pers, T H, Farh, K-H, Cuenca-Leon, E, Muona, M, Furlotte, N A, Kurth, T, Ingason, A, McMahon, G, Ligthart, L, Terwindt, G M, Kallela, M, Freilinger, T M, Ran, C, Gordon, S G, Stam, A H, Steinberg, S, Borck, G, Koiranen, M, Quaye, L, Adams, H H H, Lehtimäki, T, Sarin, A-P, Wedenoja, J, Hinds, D A, Buring, J E, Schürks, M, Ridker, P M, Hrafnsdottir, M G, Stefansson, H, Ring, S M, Hottenga, J-J, Penninx, B W J H, Färkkilä, M, Artto, V, Kaunisto, M, Vepsäläinen, S, Malik, R, Heath, A C, Madden, P A F, Martin, N G, Montgomery, G W, Kurki, M I, Kals, M, Stergiakouli, E, Smith, G D 2016, ' Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine ', Nature Genetics, vol. 48, no. 8, pp. 856-66 . https://doi.org/10.1038/ng.3598
Migraine is a debilitating neurological disorder affecting around one in seven people worldwide, but its molecular mechanisms remain poorly understood. There is some debate about whether migraine is a disease of vascular dysfunction or a result of ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b91b1615fdb6badd6cf24af716bb7404
https://doi.org/10.1038/ng.3598
https://doi.org/10.1038/ng.3598
Autor:
Dennis O. Mook-Kanamori, Yalda Jamshidi, Peter K. Joshi, Seung Hoan Choi, Henry J. Lin, Rebecca D. Jackson, Alison D. Murray, May E. Montasser, Veikko Salomaa, Charles Kooperberg, Moritz F. Sinner, Gianfranco Sinagra, Luisa Foco, James G. Wilson, Johan Sundström, Kathleen A. Ryan, Eric A. Whitsel, Bruno H. Stricker, Sandosh Padmanabhan, Christopher Newton-Cheh, Ozren Polasek, Unnur Thorsteinsdottir, Niek Verweij, Pier D. Lambiase, Nathan R. Tucker, Stefan Kääb, Jun Ding, Stefan Weiss, Daniel F. Gudbjartsson, David Conen, Lars Lind, Ivana Kolcic, Lu-Chen Weng, J. Wouter Jukema, Kirill V. Tarasov, Xiuqing Guo, Stella Trompet, Patricia B. Munroe, Albert V. Smith, Elsayed Z. Soliman, Andrew Tinker, Antti Jula, J. Gustav Smith, Alexander P. Reiner, Sébastien Thériault, Kathryn L. Lunetta, Vilmundur Gudnason, Mika Kähönen, Massimo Mangino, Raymond Noordam, Joshua C. Bis, Alan R. Shuldiner, Tim D. Spector, Borbala Mifsud, Stefan van Duijvenboden, Jeffrey R. O'Connell, Emelia J. Benjamin, M. Benjamin Shoemaker, Stephan B. Felix, Peter W. Macfarlane, Lorenz Risch, Uwe Völker, Stephanie M. Gogarten, Maria Fernanda Lima-Costa, Julia Ramirez, Morten S. Olesen, Konstantin Strauch, Annette Peters, Aaron Isaacs, Steven A. Lubitz, Eric Boerwinkle, Carolina Roselli, James H. Cartwright, Nathalia M. Araujo, Ruth J. F. Loos, Diane Fatkin, Harry Campbell, Blair H. Smith, Thomas Meitinger, André G. Uitterlinden, Paul L. Huang, Tamara B. Harris, Kathleen F. Kerr, David J. Porteous, Martina Müller-Nurasyid, Francesco Cucca, Michiel Rienstra, Davíð O. Arnar, Amanda A. Seyerle, Caroline Hayward, M. Abdullah Said, Catriona L. K. Barnes, Kent D. Taylor, Nona Sotoodehnia, Nina Mononen, Dan M. Roden, Jonathan Marten, Terho Lehtimäki, Dan E. Arking, Anna F. Dominiczak, Jan A. Kors, Olli T. Raitakari, Igor Rudan, Yordi J. van de Vegte, Christopher P. Nelson, Erik Ingelsson, Ulrike Peters, Girish N. Nadkarni, Eduardo Tarazona-Santos, Edward G. Lakatta, Nina Hutri-Kähönen, Bruce M. Psaty, Patrick T. Ellinor, Christian Fuchsberger, Katharina Schramm, Amelia W. Hall, M. Yldau van der Ende, Alvaro Alonso, James F. Wilson, Sheila Ulivi, Rosa B. Thorolfsdottir, Stefanie Aeschbacher, Mary L. Biggs, Marten E. van den Berg, Nilesh J. Samani, Thibaud Boutin, Vilmantas Giedraitis, Honghuang Lin, Kjell Nikus, Helen R. Warren, Arie C. Maan, James J. Cranley, Adolfo Correa, Martin Gögele, Ian Ford, Katri Sääksjärvi, Georg Ehret, Michele Orini, Susan R. Heckbert, Cecilia M. Lindgren, Jie Yao, Maria Pina Concas, Pim van der Harst, Ioanna Ntalla, Jeffrey Haessler, Jerome I. Rotter, Pashupati P. Mishra, Michael J. Cutler, Erwin P. Bottinger, Cornelia M. van Duijn, Jennifer A. Brody, Paolo Gasparini, Lenore J. Launer, Andrew P. Morris, Renée de Mutsert, Aki S. Havulinna, James P. Cook, Hilma Holm, Patrick Sulem, Alessandro De Grandi, Cristian Pattaro, Gardar Sveinbjornsson, Antonio Luiz Pinho Ribeiro, Mark J. Caulfield, Gudmar Thorleifsson, Marcus Dörr, Muhammad B. Riaz, Peter P. Pramstaller, Yong Qian, Anubha Mahajan, Cathy C. Laurie, Kenneth Rice, Mark Chaffin, Kari Stefansson, Andrew A. Hicks, Solmaz Assa, Hao Mei, Leo-Pekka Lyytikäinen, Fabiola Del Greco M, Renan P. Souza, Michael Preuss, Adrienne M. Stilp, Barry London, Melanie Waldenberger, Christy L. Avery, Daniel Levy, Michael R. Barnes
Publikováno v:
Nature Communications, 11(1). Nature Publishing Group
Nature Communications, 11(1):2542. Nature Publishing Group
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications, 11(1). NATURE PUBLISHING GROUP
Ntalla, I, Weng, L-C, Cartwright, J H, Hall, A W, Sveinbjornsson, G, Tucker, N R, Choi, S H, Chaffin, M D, Roselli, C, Barnes, M R, Mifsud, B, Warren, H R, Hayward, C, Marten, J, Cranley, J J, Concas, M P, Gasparini, P, Boutin, T, Kolcic, I, Rudan, I, Araujo, N M, Lima-Costa, M F, Ribeiro, A L P, Souza, R P, Tarazona-Santos, E, Giedraitis, V, Ingelsson, E, Mahajan, A, Morris, A P, Del Greco M, F, Foco, L, Gögele, M, Hicks, A A, Lind, L, Lindgren, C M, Sundström, J, Nelson, C P, Riaz, M B, Samani, N J, Sinagra, G, Ulivi, S, Kähönen, M, Mishra, P P, Mononen, N, Nikus, K, Caulfield, M J, Dominiczak, A, Padmanabhan, S, Montasser, M E, O'Connell, J R, Ryan, K, Shuldiner, A R, Aeschbacher, S, Conen, D, Risch, L, Thériault, S, Hutri-Kähönen, N, Lehtimäki, T, Lyytikäinen, L-P, Raitakari, O T, Barnes, C L K, Campbell, H, Joshi, P K, Wilson, J, Isaacs, A, Kors, J A, van Duijn, C M, Huang, P L, Gudnason, V, Harris, T B, Launer, L J, Smith, A V, Bottinger, E P, Loos, R J F, Nadkarni, G N, Preuss, M H, Correa, A, Mei, H, Wilson, J, Meitinger, T, Müller-Nurasyid, M, Peters, A, Waldenberger, M, Mangino, M, Spector, T D, Rienstra, M, van de Vegte, Y J, van der Harst, P, Verweij, N, Kääb, S, Schramm, K, Sinner, M F, Strauch, K, Cutler, M J, Fatkin, D, London, B, Olesen, M, Roden, D M, Benjamin Shoemaker, M, Gustav Smith, J, Biggs, M L, Bis, J C, Brody, J A, Psaty, B M, Rice, K, Sotoodehnia, N, De Grandi, A, Fuchsberger, C, Pattaro, C, Pramstaller, P P, Ford, I, Wouter Jukema, J, Macfarlane, P W, Trompet, S, Dörr, M, Felix, S B, Völker, U, Weiss, S, Havulinna, A S, Jula, A, Sääksjärvi, K, Salomaa, V, Guo, X, Heckbert, S R, Lin, H J, Rotter, J I, Taylor, K D, Yao, J, de Mutsert, R, Maan, A C, Mook-Kanamori, D O, Noordam, R, Cucca, F, Ding, J, Lakatta, E G, Qian, Y, Tarasov, K V, Levy, D, Lin, H, Newton-Cheh, C H, Lunetta, K L, Murray, A D, Porteous, D J, Smith, B H, Stricker, B H, Uitterlinden, A, van den Berg, M E, Haessler, J, Jackson, R D, Kooperberg, C, Peters, U, Reiner, A P, Whitsel, E A, Alonso, A, Arking, D E, Boerwinkle, E, Ehret, G B, Soliman, E Z, Avery, C L, Gogarten, S M, Kerr, K F, Laurie, C C, Seyerle, A A, Stilp, A, Assa, S, Abdullah Said, M, Yldau van der Ende, M, Lambiase, P D, Orini, M, Ramirez, J, Van Duijvenboden, S, Arnar, D O, Gudbjartsson, D F, Holm, H, Sulem, P, Thorleifsson, G, Thorolfsdottir, R B, Thorsteinsdottir, U, Benjamin, E J, Tinker, A, Stefansson, K, Ellinor, P T, Jamshidi, Y, Lubitz, S A & Munroe, P B 2020, ' Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction ', Nature Communications, vol. 11, no. 1, pp. 2542 . https://doi.org/10.1038/s41467-020-15706-x
Ntalla, I, Weng, L C, Cartwright, J H, Hall, A W, Sveinbjornsson, G, Tucker, N R, Choi, S H, Chaffin, M D, Roselli, C, Barnes, M R, Mifsud, B, Warren, H R, Hayward, C, Marten, J, Cranley, J J, Concas, M P, Gasparini, P, Boutin, T, Kolcic, I, Polasek, O, Rudan, I, Araujo, N M, Lima-Costa, M F, Ribeiro, A L P, Souza, R P, Tarazona-Santos, E, Giedraitis, V, Ingelsson, E, Mahajan, A, Morris, A P, Del Greco M, F, Foco, L, Gögele, M, Hicks, A A, Cook, J P, Lind, L, Lindgren, C M, Sundström, J, Nelson, C P, Riaz, M B, Samani, N J, Sinagra, G, Ulivi, S, Kähönen, M, Mishra, P P, Mononen, N, Nikus, K, Caulfield, M J, Dominiczak, A, Padmanabhan, S, Montasser, M E, O’Connell, J R, Ryan, K, Shuldiner, A R, Aeschbacher, S, Conen, D, Risch, L, Thériault, S, Hutri-Kähönen, N, Lehtimäki, T, Lyytikäinen, L P, Raitakari, O T, Barnes, C L K, Campbell, H, Joshi, P K, Wilson, J F, Isaacs, A, Kors, J A, van Duijn, C M, Huang, P L, Gudnason, V, Harris, T B, Launer, L J, Smith, A V, Bottinger, E P, Loos, R J F, Nadkarni, G N, Preuss, M H, Correa, A, Mei, H, Wilson, J, Meitinger, T, Müller-Nurasyid, M, Peters, A, Waldenberger, M, Mangino, M, Spector, T D, Rienstra, M, van de Vegte, Y J, van der Harst, P, Verweij, N, Kääb, S, Schramm, K, Sinner, M F, Strauch, K, Cutler, M J, Fatkin, D, London, B, Olesen, M, Roden, D M, Benjamin Shoemaker, M, Gustav Smith, J, Biggs, M L, Bis, J C, Brody, J A, Psaty, B M, Rice, K, Sotoodehnia, N, De Grandi, A, Fuchsberger, C, Pattaro, C, Pramstaller, P P, Ford, I, Wouter Jukema, J, Macfarlane, P W, Trompet, S, Dörr, M, Felix, S B, Völker, U, Weiss, S, Havulinna, A S, Jula, A, Sääksjärvi, K, Salomaa, V, Guo, X, Heckbert, S R, Lin, H J, Rotter, J I, Taylor, K D, Yao, J, de Mutsert, R, Maan, A C, Mook-Kanamori, D O, Noordam, R, Cucca, F, Ding, J, Lakatta, E G, Qian, Y, Tarasov, K V, Levy, D, Lin, H, Newton-Cheh, C H, Lunetta, K L, Murray, A D, Porteous, D J, Smith, B H, Stricker, B H, Uitterlinden, A, van den Berg, M E, Haessler, J, Jackson, R D, Kooperberg, C, Peters, U, Reiner, A P, Whitsel, E A, Alonso, A, Arking, D E, Boerwinkle, E, Ehret, G B, Soliman, E Z, Avery, C L, Gogarten, S M, Kerr, K F, Laurie, C C, Seyerle, A A, Stilp, A, Assa, S, Abdullah Said, M, Yldau van der Ende, M, Lambiase, P D, Orini, M, Ramirez, J, Van Duijvenboden, S, Arnar, D O, Gudbjartsson, D F, Holm, H, Sulem, P, Thorleifsson, G, Thorolfsdottir, R B, Thorsteinsdottir, U, Benjamin, E J, Tinker, A, Stefansson, K, Ellinor, P T, Jamshidi, Y, Lubitz, S A & Munroe, P B 2020, ' Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction ', Nature Communications, vol. 11, no. 1, 2542 . https://doi.org/10.1038/s41467-020-15706-x
Ntalla, I, Weng, L-C, Cartwright, J H, Hall, A W, Sveinbjornsson, G, Tucker, N R, Choi, S H, Chaffin, M D, Roselli, C, Barnes, M R, Mifsud, B, Warren, H R, Hayward, C, Marten, J, Cranley, J J, Concas, M P, Gasparini, P, Boutin, T, Kolcic, I, Polasek, O, Rudan, I, Araujo, N M, Lima-Costa, M F, Ribeiro, A L P, Souza, R P, Tarazona-Santos, E, Giedraitis, V, Ingelsson, E, Mahajan, A, Morris, A P, Del Greco M, F, Foco, L, Gögele, M, Hicks, A A, Cook, J P, Lind, L, Lindgren, C M, Sundström, J, Nelson, C P, Riaz, M B, Samani, N J, Sinagra, G, Ulivi, S, Kähönen, M, Mishra, P P, Mononen, N, Nikus, K, Caulfield, M J, Dominiczak, A, Padmanabhan, S, Montasser, M E, O'Connell, J R, Ryan, K, Shuldiner, A R, Aeschbacher, S, Conen, D, Risch, L, Thériault, S, Hutri-Kähönen, N, Lehtimäki, T, Lyytikäinen, L-P, Raitakari, O T, Barnes, C L K, Campbell, H, Joshi, P K, Wilson, J F, Isaacs, A, Kors, J A, van Duijn, C M, Huang, P L, Gudnason, V, Harris, T B, Launer, L J, Smith, A V, Bottinger, E P, Loos, R J F, Nadkarni, G N, Preuss, M H, Correa, A, Mei, H, Wilson, J, Meitinger, T, Müller-Nurasyid, M, Peters, A, Waldenberger, M, Mangino, M, Spector, T D, Rienstra, M, van de Vegte, Y J, van der Harst, P, Verweij, N, Kääb, S, Schramm, K, Sinner, M F, Strauch, K, Cutler, M J, Fatkin, D, London, B, Olesen, M, Roden, D M, Benjamin Shoemaker, M, Gustav Smith, J, Biggs, M L, Bis, J C, Brody, J A, Psaty, B M, Rice, K, Sotoodehnia, N, De Grandi, A, Fuchsberger, C, Pattaro, C, Pramstaller, P P, Ford, I, Wouter Jukema, J, Macfarlane, P W, Trompet, S, Dörr, M, Felix, S B, Völker, U, Weiss, S, Havulinna, A S, Jula, A, Sääksjärvi, K, Salomaa, V, Guo, X, Heckbert, S R, Lin, H J, Rotter, J I, Taylor, K D, Yao, J, de Mutsert, R, Maan, A C, Mook-Kanamori, D O, Noordam, R, Cucca, F, Ding, J, Lakatta, E G, Qian, Y, Tarasov, K V, Levy, D, Lin, H, Newton-Cheh, C H, Lunetta, K L, Murray, A D, Porteous, D J, Smith, B H, Stricker, B H, Uitterlinden, A, van den Berg, M E, Haessler, J, Jackson, R D, Kooperberg, C, Peters, U, Reiner, A P, Whitsel, E A, Alonso, A, Arking, D E, Boerwinkle, E, Ehret, G B, Soliman, E Z, Avery, C L, Gogarten, S M, Kerr, K F, Laurie, C C, Seyerle, A A, Stilp, A, Assa, S, Abdullah Said, M, Yldau van der Ende, M, Lambiase, P D, Orini, M, Ramirez, J, Van Duijvenboden, S, Arnar, D O, Gudbjartsson, D F, Holm, H, Sulem, P, Thorleifsson, G, Thorolfsdottir, R B, Thorsteinsdottir, U, Benjamin, E J, Tinker, A, Stefansson, K, Ellinor, P T, Jamshidi, Y, Lubitz, S A & Munroe, P B 2020, ' Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction ', Nature Communications, vol. 11, no. 1, pp. 2542 . https://doi.org/10.1038/s41467-020-15706-x
Nature Communications, 11(1):2542. Nature Publishing Group
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications, 11(1). NATURE PUBLISHING GROUP
Ntalla, I, Weng, L-C, Cartwright, J H, Hall, A W, Sveinbjornsson, G, Tucker, N R, Choi, S H, Chaffin, M D, Roselli, C, Barnes, M R, Mifsud, B, Warren, H R, Hayward, C, Marten, J, Cranley, J J, Concas, M P, Gasparini, P, Boutin, T, Kolcic, I, Rudan, I, Araujo, N M, Lima-Costa, M F, Ribeiro, A L P, Souza, R P, Tarazona-Santos, E, Giedraitis, V, Ingelsson, E, Mahajan, A, Morris, A P, Del Greco M, F, Foco, L, Gögele, M, Hicks, A A, Lind, L, Lindgren, C M, Sundström, J, Nelson, C P, Riaz, M B, Samani, N J, Sinagra, G, Ulivi, S, Kähönen, M, Mishra, P P, Mononen, N, Nikus, K, Caulfield, M J, Dominiczak, A, Padmanabhan, S, Montasser, M E, O'Connell, J R, Ryan, K, Shuldiner, A R, Aeschbacher, S, Conen, D, Risch, L, Thériault, S, Hutri-Kähönen, N, Lehtimäki, T, Lyytikäinen, L-P, Raitakari, O T, Barnes, C L K, Campbell, H, Joshi, P K, Wilson, J, Isaacs, A, Kors, J A, van Duijn, C M, Huang, P L, Gudnason, V, Harris, T B, Launer, L J, Smith, A V, Bottinger, E P, Loos, R J F, Nadkarni, G N, Preuss, M H, Correa, A, Mei, H, Wilson, J, Meitinger, T, Müller-Nurasyid, M, Peters, A, Waldenberger, M, Mangino, M, Spector, T D, Rienstra, M, van de Vegte, Y J, van der Harst, P, Verweij, N, Kääb, S, Schramm, K, Sinner, M F, Strauch, K, Cutler, M J, Fatkin, D, London, B, Olesen, M, Roden, D M, Benjamin Shoemaker, M, Gustav Smith, J, Biggs, M L, Bis, J C, Brody, J A, Psaty, B M, Rice, K, Sotoodehnia, N, De Grandi, A, Fuchsberger, C, Pattaro, C, Pramstaller, P P, Ford, I, Wouter Jukema, J, Macfarlane, P W, Trompet, S, Dörr, M, Felix, S B, Völker, U, Weiss, S, Havulinna, A S, Jula, A, Sääksjärvi, K, Salomaa, V, Guo, X, Heckbert, S R, Lin, H J, Rotter, J I, Taylor, K D, Yao, J, de Mutsert, R, Maan, A C, Mook-Kanamori, D O, Noordam, R, Cucca, F, Ding, J, Lakatta, E G, Qian, Y, Tarasov, K V, Levy, D, Lin, H, Newton-Cheh, C H, Lunetta, K L, Murray, A D, Porteous, D J, Smith, B H, Stricker, B H, Uitterlinden, A, van den Berg, M E, Haessler, J, Jackson, R D, Kooperberg, C, Peters, U, Reiner, A P, Whitsel, E A, Alonso, A, Arking, D E, Boerwinkle, E, Ehret, G B, Soliman, E Z, Avery, C L, Gogarten, S M, Kerr, K F, Laurie, C C, Seyerle, A A, Stilp, A, Assa, S, Abdullah Said, M, Yldau van der Ende, M, Lambiase, P D, Orini, M, Ramirez, J, Van Duijvenboden, S, Arnar, D O, Gudbjartsson, D F, Holm, H, Sulem, P, Thorleifsson, G, Thorolfsdottir, R B, Thorsteinsdottir, U, Benjamin, E J, Tinker, A, Stefansson, K, Ellinor, P T, Jamshidi, Y, Lubitz, S A & Munroe, P B 2020, ' Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction ', Nature Communications, vol. 11, no. 1, pp. 2542 . https://doi.org/10.1038/s41467-020-15706-x
Ntalla, I, Weng, L C, Cartwright, J H, Hall, A W, Sveinbjornsson, G, Tucker, N R, Choi, S H, Chaffin, M D, Roselli, C, Barnes, M R, Mifsud, B, Warren, H R, Hayward, C, Marten, J, Cranley, J J, Concas, M P, Gasparini, P, Boutin, T, Kolcic, I, Polasek, O, Rudan, I, Araujo, N M, Lima-Costa, M F, Ribeiro, A L P, Souza, R P, Tarazona-Santos, E, Giedraitis, V, Ingelsson, E, Mahajan, A, Morris, A P, Del Greco M, F, Foco, L, Gögele, M, Hicks, A A, Cook, J P, Lind, L, Lindgren, C M, Sundström, J, Nelson, C P, Riaz, M B, Samani, N J, Sinagra, G, Ulivi, S, Kähönen, M, Mishra, P P, Mononen, N, Nikus, K, Caulfield, M J, Dominiczak, A, Padmanabhan, S, Montasser, M E, O’Connell, J R, Ryan, K, Shuldiner, A R, Aeschbacher, S, Conen, D, Risch, L, Thériault, S, Hutri-Kähönen, N, Lehtimäki, T, Lyytikäinen, L P, Raitakari, O T, Barnes, C L K, Campbell, H, Joshi, P K, Wilson, J F, Isaacs, A, Kors, J A, van Duijn, C M, Huang, P L, Gudnason, V, Harris, T B, Launer, L J, Smith, A V, Bottinger, E P, Loos, R J F, Nadkarni, G N, Preuss, M H, Correa, A, Mei, H, Wilson, J, Meitinger, T, Müller-Nurasyid, M, Peters, A, Waldenberger, M, Mangino, M, Spector, T D, Rienstra, M, van de Vegte, Y J, van der Harst, P, Verweij, N, Kääb, S, Schramm, K, Sinner, M F, Strauch, K, Cutler, M J, Fatkin, D, London, B, Olesen, M, Roden, D M, Benjamin Shoemaker, M, Gustav Smith, J, Biggs, M L, Bis, J C, Brody, J A, Psaty, B M, Rice, K, Sotoodehnia, N, De Grandi, A, Fuchsberger, C, Pattaro, C, Pramstaller, P P, Ford, I, Wouter Jukema, J, Macfarlane, P W, Trompet, S, Dörr, M, Felix, S B, Völker, U, Weiss, S, Havulinna, A S, Jula, A, Sääksjärvi, K, Salomaa, V, Guo, X, Heckbert, S R, Lin, H J, Rotter, J I, Taylor, K D, Yao, J, de Mutsert, R, Maan, A C, Mook-Kanamori, D O, Noordam, R, Cucca, F, Ding, J, Lakatta, E G, Qian, Y, Tarasov, K V, Levy, D, Lin, H, Newton-Cheh, C H, Lunetta, K L, Murray, A D, Porteous, D J, Smith, B H, Stricker, B H, Uitterlinden, A, van den Berg, M E, Haessler, J, Jackson, R D, Kooperberg, C, Peters, U, Reiner, A P, Whitsel, E A, Alonso, A, Arking, D E, Boerwinkle, E, Ehret, G B, Soliman, E Z, Avery, C L, Gogarten, S M, Kerr, K F, Laurie, C C, Seyerle, A A, Stilp, A, Assa, S, Abdullah Said, M, Yldau van der Ende, M, Lambiase, P D, Orini, M, Ramirez, J, Van Duijvenboden, S, Arnar, D O, Gudbjartsson, D F, Holm, H, Sulem, P, Thorleifsson, G, Thorolfsdottir, R B, Thorsteinsdottir, U, Benjamin, E J, Tinker, A, Stefansson, K, Ellinor, P T, Jamshidi, Y, Lubitz, S A & Munroe, P B 2020, ' Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction ', Nature Communications, vol. 11, no. 1, 2542 . https://doi.org/10.1038/s41467-020-15706-x
Ntalla, I, Weng, L-C, Cartwright, J H, Hall, A W, Sveinbjornsson, G, Tucker, N R, Choi, S H, Chaffin, M D, Roselli, C, Barnes, M R, Mifsud, B, Warren, H R, Hayward, C, Marten, J, Cranley, J J, Concas, M P, Gasparini, P, Boutin, T, Kolcic, I, Polasek, O, Rudan, I, Araujo, N M, Lima-Costa, M F, Ribeiro, A L P, Souza, R P, Tarazona-Santos, E, Giedraitis, V, Ingelsson, E, Mahajan, A, Morris, A P, Del Greco M, F, Foco, L, Gögele, M, Hicks, A A, Cook, J P, Lind, L, Lindgren, C M, Sundström, J, Nelson, C P, Riaz, M B, Samani, N J, Sinagra, G, Ulivi, S, Kähönen, M, Mishra, P P, Mononen, N, Nikus, K, Caulfield, M J, Dominiczak, A, Padmanabhan, S, Montasser, M E, O'Connell, J R, Ryan, K, Shuldiner, A R, Aeschbacher, S, Conen, D, Risch, L, Thériault, S, Hutri-Kähönen, N, Lehtimäki, T, Lyytikäinen, L-P, Raitakari, O T, Barnes, C L K, Campbell, H, Joshi, P K, Wilson, J F, Isaacs, A, Kors, J A, van Duijn, C M, Huang, P L, Gudnason, V, Harris, T B, Launer, L J, Smith, A V, Bottinger, E P, Loos, R J F, Nadkarni, G N, Preuss, M H, Correa, A, Mei, H, Wilson, J, Meitinger, T, Müller-Nurasyid, M, Peters, A, Waldenberger, M, Mangino, M, Spector, T D, Rienstra, M, van de Vegte, Y J, van der Harst, P, Verweij, N, Kääb, S, Schramm, K, Sinner, M F, Strauch, K, Cutler, M J, Fatkin, D, London, B, Olesen, M, Roden, D M, Benjamin Shoemaker, M, Gustav Smith, J, Biggs, M L, Bis, J C, Brody, J A, Psaty, B M, Rice, K, Sotoodehnia, N, De Grandi, A, Fuchsberger, C, Pattaro, C, Pramstaller, P P, Ford, I, Wouter Jukema, J, Macfarlane, P W, Trompet, S, Dörr, M, Felix, S B, Völker, U, Weiss, S, Havulinna, A S, Jula, A, Sääksjärvi, K, Salomaa, V, Guo, X, Heckbert, S R, Lin, H J, Rotter, J I, Taylor, K D, Yao, J, de Mutsert, R, Maan, A C, Mook-Kanamori, D O, Noordam, R, Cucca, F, Ding, J, Lakatta, E G, Qian, Y, Tarasov, K V, Levy, D, Lin, H, Newton-Cheh, C H, Lunetta, K L, Murray, A D, Porteous, D J, Smith, B H, Stricker, B H, Uitterlinden, A, van den Berg, M E, Haessler, J, Jackson, R D, Kooperberg, C, Peters, U, Reiner, A P, Whitsel, E A, Alonso, A, Arking, D E, Boerwinkle, E, Ehret, G B, Soliman, E Z, Avery, C L, Gogarten, S M, Kerr, K F, Laurie, C C, Seyerle, A A, Stilp, A, Assa, S, Abdullah Said, M, Yldau van der Ende, M, Lambiase, P D, Orini, M, Ramirez, J, Van Duijvenboden, S, Arnar, D O, Gudbjartsson, D F, Holm, H, Sulem, P, Thorleifsson, G, Thorolfsdottir, R B, Thorsteinsdottir, U, Benjamin, E J, Tinker, A, Stefansson, K, Ellinor, P T, Jamshidi, Y, Lubitz, S A & Munroe, P B 2020, ' Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction ', Nature Communications, vol. 11, no. 1, pp. 2542 . https://doi.org/10.1038/s41467-020-15706-x
Publisher's version (útgefin grein)
The electrocardiographic PR interval reflects atrioventricular conduction, and is associated with conduction abnormalities, pacemaker implantation, atrial fibrillation (AF), and cardiovascular mortality. Here
The electrocardiographic PR interval reflects atrioventricular conduction, and is associated with conduction abnormalities, pacemaker implantation, atrial fibrillation (AF), and cardiovascular mortality. Here
Autor:
Christian P. Müller, Patricia B. Munroe, Philipp S. Wild, Teresa Trenkwalder, Christian Hengstenberg, Georg Schmidt, Yalda Jamshidi, Stephan B. Felix, Renate B. Schnabel, Nilesh J. Samani, Jan A. Kors, Peter S. Braund, Bruno H. Stricker, Bernhard M. Kaess, Solmaz Assa, C. Pattaro, Uwe Völker, Matthias Nauck, M. Arfan Ikram, Thomas Münzel, Mobeen Zafar, Isabel Deisenhofer, Niek Verweij, Alexander Teumer, Alessandra Rossini, Christopher P. Nelson, Thorsten Kessler, Anna F. Dominiczak, Tim D. Spector, Harold Snieder, Marten E. van den Berg, André G. Uitterlinden, Rachel Bastiaenen, Maryam Kavousi, Christian Fuchsberger, Sandosh Padmanabhan, Claudia P. Cabrera, Leanne M. Hall, Klaus Stark, Helen R. Warren, Norbert Pfeiffer, Heribert Schunkert, Karl J. Lackner, Ilja M. Nolte, Elijah R. Behr, Marcus Dörr, Peter P. Pramstaller, Marzia De Bortoli, Martin Gögele, Pim van der Harst, Wibke Reinhard
Publikováno v:
JCI Insight, 4(23):131156. AMER SOC CLINICAL INVESTIGATION INC
JCI insight, 4(23):e131156. The American Society for Clinical Investigation
JCI insight, 4(23):e131156. The American Society for Clinical Investigation
BACKGROUND: The presence of an early repolarization pattern (ERP) on the surface ECG is associated with risk of ventricular fibrillation and sudden cardiac death. Family studies have shown that ERP is a highly heritable trait, but molecular genetic d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2760022c55c28cb105eb8519ce2ad42
https://research.rug.nl/en/publications/f381dbd6-a884-4b57-ad58-b6fa7d504694
https://research.rug.nl/en/publications/f381dbd6-a884-4b57-ad58-b6fa7d504694