Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Mohlke KL"'
Autor:
Jia Q; 1 Department of Preventive Medicine Keck School of Medicine, University of Southern California Los Angeles CA.; 2 Department of Biochemistry & Molecular Medicine Keck School of Medicine, University of Southern California Los Angeles CA., Han Y; 1 Department of Preventive Medicine Keck School of Medicine, University of Southern California Los Angeles CA.; 2 Department of Biochemistry & Molecular Medicine Keck School of Medicine, University of Southern California Los Angeles CA., Huang P; 1 Department of Preventive Medicine Keck School of Medicine, University of Southern California Los Angeles CA.; 2 Department of Biochemistry & Molecular Medicine Keck School of Medicine, University of Southern California Los Angeles CA.; 3 Xiangya School of Medicine Central South University Hunan China., Woodward NC; 1 Department of Preventive Medicine Keck School of Medicine, University of Southern California Los Angeles CA.; 2 Department of Biochemistry & Molecular Medicine Keck School of Medicine, University of Southern California Los Angeles CA., Gukasyan J; 1 Department of Preventive Medicine Keck School of Medicine, University of Southern California Los Angeles CA.; 2 Department of Biochemistry & Molecular Medicine Keck School of Medicine, University of Southern California Los Angeles CA., Kettunen J; 4 Computational Medicine Faculty of Medicine University of Oulu and Biocenter Oulu Oulu Finland.; 5 National Institute for Health and Welfare Helsinki Finland., Ala-Korpela M; 4 Computational Medicine Faculty of Medicine University of Oulu and Biocenter Oulu Oulu Finland.; 6 Systems Epidemiology Baker Heart and Diabetes Institute Melbourne Victoria Australia.; 7 NMR Metabolomics Laboratory School of Pharmacy University of Eastern Finland Kuopio Finland.; 9 Population Health Science Bristol Medical School University of Bristol United Kingdom.; 10 Medical Research Council Integrative Epidemiology Unit at the University of Bristol United Kingdom.; 11 Department of Epidemiology and Preventive Medicine School of Public Health and Preventive Medicine Faculty of Medicine Nursing and Health Sciences The Alfred Hospital Monash University Melbourne Victoria Australia., Anufrieva O; 4 Computational Medicine Faculty of Medicine University of Oulu and Biocenter Oulu Oulu Finland., Wang Q; 4 Computational Medicine Faculty of Medicine University of Oulu and Biocenter Oulu Oulu Finland.; 6 Systems Epidemiology Baker Heart and Diabetes Institute Melbourne Victoria Australia., Perola M; 5 National Institute for Health and Welfare Helsinki Finland.; 12 Estonian Genome Center University of Tartu Estonia.; 13 Institute for Molecular Medicine (FIMM) University of Helsinki Finland., Raitakari O; 14 Research Centre of Applied and Preventive Cardiovascular Medicine University of Turku Finland.; 17 Department of Clinical Physiology Turku University Hospital Turku Finland., Lehtimäki T; 18 Department of Clinical Chemistry Fimlab Laboratories and Faculty of Medicine and Health Technology Finnish Cardiovascular Research Center-Tampere Tampere University Tampere Finland., Viikari J; 15 Department of Medicine University of Turku Finland.; 16 Division of Medicine Turku University Hospital Turku Finland., Järvelin MR; 4 Computational Medicine Faculty of Medicine University of Oulu and Biocenter Oulu Oulu Finland.; 19 Department of Epidemiology and Biostatistics School of Public Health MRC-PHE Centre for Environment and Health Imperial College London London United Kingdom.; 20 Center for Life Course and Systems Epidemiology University of Oulu Finland.; 21 Unit of Primary Care Oulu University Hospital Oulu Finland., Boehnke M; 22 Department of Biostatistics and Center for Statistical Genetics University of Michigan Ann Arbor MI., Laakso M; 8 School of Medicine University of Eastern Finland Kuopio Finland., Mohlke KL; 23 Department of Genetics University of North Carolina Chapel Hill NC., Fiehn O; 24 Genome Center University of California Davis CA., Wang Z; 25 Department of Cardiovascular Medicine Cleveland Clinic Cleveland OH., Tang WHW; 25 Department of Cardiovascular Medicine Cleveland Clinic Cleveland OH.; 26 Department of Cellular & Molecular Medicine Cleveland Clinic Cleveland OH., Hazen SL; 24 Genome Center University of California Davis CA.; 25 Department of Cardiovascular Medicine Cleveland Clinic Cleveland OH., Hartiala JA; 1 Department of Preventive Medicine Keck School of Medicine, University of Southern California Los Angeles CA.; 2 Department of Biochemistry & Molecular Medicine Keck School of Medicine, University of Southern California Los Angeles CA., Allayee H; 1 Department of Preventive Medicine Keck School of Medicine, University of Southern California Los Angeles CA.; 2 Department of Biochemistry & Molecular Medicine Keck School of Medicine, University of Southern California Los Angeles CA.
Publikováno v:
Journal of the American Heart Association [J Am Heart Assoc] 2019 May 21; Vol. 8 (10), pp. e011922.
Autor:
Kilpeläinen TO; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200, Denmark. tuomas.kilpelainen@sund.ku.dk.; Department of Environmental Medicine and Public Health, The Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA. tuomas.kilpelainen@sund.ku.dk., Bentley AR; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, 20892, MD, USA., Noordam R; Internal Medicine, Gerontology and Geriatrics, Leiden University Medical Center, Leiden, 2300 RC, The Netherlands., Sung YJ; Division of Biostatistics, Washington University School of Medicine, St. Louis, 63110, MO, USA., Schwander K; Division of Biostatistics, Washington University School of Medicine, St. Louis, 63110, MO, USA., Winkler TW; Department of Genetic Epidemiology, University of Regensburg, Regensburg, 93051, Germany., Jakupović H; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200, Denmark., Chasman DI; Preventive Medicine, Brigham and Women's Hospital, Boston, 02215, MA, USA.; Harvard Medical School, Boston, 02131, MA, USA., Manning A; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston, 02114, MA, USA.; Department of Medicine, Harvard Medical School, Boston, 02115, MA, USA., Ntalla I; Clinical Pharmacology, William Harvey Research Instititute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK., Aschard H; Department of Epidemiology, Harvard School of Public Health, Boston, 02115, MA, USA.; Centre de Bioinformatique, Biostatistique et Biologie Intégrative (C3BI), Institut Pasteur, Paris, 75015, France., Brown MR; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, 77030, TX, USA., de Las Fuentes L; Division of Biostatistics, Washington University School of Medicine, St. Louis, 63110, MO, USA.; Cardiovascular Division, Department of Medicine, Washington University, St. Louis, 63110, MO, USA., Franceschini N; Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, 27514, NC, USA., Guo X; The Institute for Translational Genomics and Population Sciences, Division of Genomic Outcomes, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, 90502, CA, USA., Vojinovic D; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CE, The Netherlands., Aslibekyan S; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, 35294, AL, USA., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, 63108, MO, USA., Kho M; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, 48109, MI, USA., Musani SK; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, 39213, MS, USA., Richard M; Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, 77030, TX, USA., Wang H; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, 02115, MA, USA., Wang Z; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, 77030, TX, USA., Bartz TM; Cardiovascular Health Research Unit, Biostatistics and Medicine, University of Washington, Seattle, 98101, WA, USA., Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, 48109, MI, USA., Campbell A; Centre for Genomic & Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Dorajoo R; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, 138672, Singapore., Fisher V; Biostatistics, Boston University School of Public Health, Boston, 02118, MA, USA., Hartwig FP; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, 96020220, RS, Brazil.; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, BS8 2BN, UK., Horimoto ARVR; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo, 01246903, SP, Brazil., Li C; Epidemiology and Biostatistics, University of Giorgia at Athens College of Public Health, Athens, 30602, GA, USA., Lohman KK; Public Health Sciences, Biostatistical Sciences, Wake Forest University Health Sciences, Winston-Salem, 27157, NC, USA., Marten J; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Sim X; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, 117549, Singapore., Smith AV; Icelandic Heart Association, 201, Kopavogur, Iceland.; Department of Biostatistics, University of Michigan, Ann Arbor, 48109, MI, USA., Tajuddin SM; Health Disparities Research Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, 21224, MD, USA., Alver M; Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia., Amini M; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands., Boissel M; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, 59000, France., Chai JF; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, 117549, Singapore., Chen X; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Stockholm, 17177, Sweden., Divers J; Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, 27157, NC, USA., Evangelou E; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, 45110, Greece., Gao C; Molecular Genetics and Genomics Program, Wake Forest School of Medicine, Winston-Salem, 27157, NC, USA., Graff M; Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, 27514, NC, USA., Harris SE; Centre for Genomic & Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., He M; Department of Occupational and Environmental Health and State Key Laboratory of Environmental Health for Incubating, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430014, China., Hsu FC; Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, 27157, NC, USA., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, 48109, MI, USA., Zhao JH; MRC Epidemiology Unit, University of Cambridge, Cambridge, CB2 0QQ, UK., Kraja AT; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, 63108, MO, USA., Kühnel B; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, 85764, Germany., Laguzzi F; Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, 17177, Sweden., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, 33014, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33014, Finland., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands., Rauramaa R; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, 70100, Finland., Riaz M; College of Medicine, Biological Sciences and Psychology, Health Sciences, The Infant Mortality and Morbidity Studies (TIMMS), Leicester, LE1 7RH, UK., Robino A; Institute for Maternal and Child Health-IRCCS 'Burlo Garofolo', Trieste, 34137, Italy., Rueedi R; Department of Computational Biology, University of Lausanne, Lausanne, 1015, Switzerland.; Swiss Institute of Bioinformatics, 1015, Lausanne, Switzerland., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, 48109, MI, USA., Takeuchi F; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, 1628655, Japan., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands., Varga TV; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Skåne University Hospital, Malmö, 20502, Sweden., Verweij N; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, 9700 RB, The Netherlands., Ware EB; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, 48104, MI, USA., Wen W; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, 37203, TN, USA., Li X; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, 44106, OH, USA., Yanek LR; Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, 21287, MD, USA., Amin N; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CE, The Netherlands., Arnett DK; Dean's Office, University of Kentucky College of Public Health, Lexington, 40536, KY, USA., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, 77030, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, 77030, TX, USA., Brumat M; Department of Medical Sciences, University of Trieste, Trieste, 34137, Italy., Cade B; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, 02115, MA, USA., Canouil M; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, 59000, France., Chen YI; The Institute for Translational Genomics and Population Sciences, Division of Genomic Outcomes, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, 90502, CA, USA., Concas MP; Institute for Maternal and Child Health-IRCCS 'Burlo Garofolo', Trieste, 34137, Italy., Connell J; Ninewells Hospital & Medical School, University of Dundee, Dundee, DD1 9SY, Scotland, UK., de Mutsert R; Clinical Epidemiology, Leiden University Medical Center, Leiden, 2300 RC, Netherlands., de Silva HJ; Department of Medicine, Faculty of Medicine, University of Kelaniya, Ragama, 11600, Sri Lanka., de Vries PS; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, 77030, TX, USA., Demirkan A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CE, The Netherlands., Ding J; Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, 27157, NC, USA., Eaton CB; Department of Family Medicine and Epidemiology, Alpert Medical School of Brown University, Providence, 02860, RI, USA., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, 48104, MI, USA., Friedlander Y; Braun School of Public Health, Hebrew University-Hadassah Medical Center, Jerusalem, 91120, Israel., Gabriel KP; Department of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Austin, Austin, 78712, TX, USA., Ghanbari M; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CE, The Netherlands.; Department of Genetics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, 91778-99191, Iran., Giulianini F; Preventive Medicine, Brigham and Women's Hospital, Boston, 02215, MA, USA., Gu CC; Division of Biostatistics, Washington University School of Medicine, St. Louis, 63110, MO, USA., Gu D; Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100006, China., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Bethesda, 20892, MD, USA., He J; Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, 70112, LA, USA.; Medicine, Tulane University School of Medicine, New Orleans, 70112, LA, USA., Heikkinen S; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, 70211, Finland.; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, 70210, Finland., Heng CK; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore.; Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore, 119228, Singapore., Hunt SC; Division of Epidemiology, Department of Internal Medicine, University of Utah, Salt Lake City, 84132, UT, USA.; Department of Genetic Medicine, Weill Cornell Medicine, Doha, 24144, Qatar., Ikram MA; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CE, The Netherlands.; Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, 3015 GD, The Netherlands., Jonas JB; Department of Ophthalmology, Medical Faculty Mannheim, University Heidelberg, Mannheim, 68167, Germany.; Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Ophthalmology and Visual Science Key Lab, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China., Koh WP; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, 117549, Singapore.; Health Services and Systems Research, Duke-NUS Medical School, Singapore, 169857, Singapore., Komulainen P; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, 70100, Finland., Krieger JE; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo, 01246903, SP, Brazil., Kritchevsky SB; Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, 27157, NC, USA., Kutalik Z; Swiss Institute of Bioinformatics, 1015, Lausanne, Switzerland.; Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, 1010, Switzerland., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, 70210, Finland., Langefeld CD; Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, 27157, NC, USA., Langenberg C; MRC Epidemiology Unit, University of Cambridge, Cambridge, CB2 0QQ, UK., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Bethesda, 20892, MD, USA., Leander K; Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, 17177, Sweden., Lemaitre RN; Cardiovascular Health Research Unit, Medicine, University of Washington, Seattle, 98101, WA, USA., Lewis CE; Division of Preventive Medicine, Department of Medicine, University of Alabama at Birmingham, School of Medicine, Birmingham, 35294, AL, USA., Liang J; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, 44106, OH, USA., Liu J; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, 138672, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117597, Singapore., Mägi R; Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia., Manichaikul A; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, 22908, VA, USA., Meitinger T; Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Institute of Human Genetics, Technische Universität München, Munich, 80333, Germany., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia., Milaneschi Y; Department of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, VU University Medical Center, Amsterdam, 1081 HV, The Netherlands., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, 27514, NC, USA., Mosley TH Jr; Geriatrics, Medicine, University of Mississippi, Jackson, 39216, MS, USA., Murray AD; The Institute of Medical Sciences, Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, AB25 2ZD, UK., Nalls MA; Molecular Genetics Section, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, 20892, MD, USA.; Data Tecnica International, Glen Echo, 20812, MD, USA., Nang EK; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, 117549, Singapore., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Leicester, LE3 9PQ, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, LE3 9QD, UK., Nona S; Cardiovascular Health Research Unit, Division of Cardiology, University of Washington, Seattle, 98101, WA, USA., Norris JM; Department of Epidemiology, University of Colorado Denver, Aurora, 80045, CO, USA., Nwuba CV; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200, Denmark., O'Connell J; Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, 21201, MD, USA.; Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, 21201, MD, USA., Palmer ND; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, 27157, NC, USA., Papanicolau GJ; Epidemiology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, 20892, MD, USA., Pazoki R; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Stockholm, 17177, Sweden., Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, 85764, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Neuherberg, 85764, Germany., Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, 48109, MI, USA., Polasek O; Department of Public Health, Department of Medicine, University of Split, Split, 21000, Croatia.; Psychiatric Hospital 'Sveti Ivan', Zagreb, 10000, Croatia.; Gen-Info Ltd., 10000, Zagreb, Croatia., Porteous DJ; Centre for Genomic & Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Poveda A; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Skåne University Hospital, Malmö, 20502, Sweden., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, 20521, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, 20520, Finland., Rich SS; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, 22908, VA, USA., Risch N; Institute for Human Genetics, Department of Epidemiology and Biostatistics, University of California, San Francisco, 94143, CA, USA., Robinson JG; Department of Epidemiology and Medicine, University of Iowa, Iowa City, 52242, IA, USA., Rose LM; Preventive Medicine, Brigham and Women's Hospital, Boston, 02215, MA, USA., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, EH16 4UX, UK., Schreiner PJ; Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, 55454, MN, USA., Scott RA; MRC Epidemiology Unit, University of Cambridge, Cambridge, CB2 0QQ, UK., Sidney SS; Kaiser Permanente Washington, Health Research Institute, Seattle, 98101, WA, USA., Sims M; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, 39213, MS, USA., Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, 48109, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, 48104, MI, USA., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands., Sofer T; Department of Medicine, Harvard Medical School, Boston, 02115, MA, USA.; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, 02115, MA, USA., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Alzheimer Scotland Dementia Research Centre, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Sternfeld B; Kaiser Permanente Washington, Health Research Institute, Seattle, 98101, WA, USA., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Institute of Medical Informatics Biometry and Epidemiology, Ludwig-Maximilians-Universitat Munchen, Munich, 81377, Germany., Tang H; Department of Genetics, Stanford University, Stanford, 94305, CA, USA., Taylor KD; The Institute for Translational Genomics and Population Sciences, Division of Genomic Outcomes, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, 90502, CA, USA., Tsai MY; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, 55455, MN, USA., Tuomilehto J; Public Health Solutions, National Institute for Health and Welfare, Helsinki, 00271, Finland.; Diabetes Research Group, King Abdulaziz University, Jeddah, 21589, Saudi Arabia., Uitterlinden AG; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, 3015 CE, The Netherlands., van der Ende MY; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, 9700 RB, The Netherlands., van Heemst D; Internal Medicine, Gerontology and Geriatrics, Leiden University Medical Center, Leiden, 2300 RC, The Netherlands., Voortman T; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CE, The Netherlands., Waldenberger M; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, 85764, Germany., Wennberg P; Department of Public Health & Clinical Medicine, Umeå University, Umeå, 90185, Västerbotten, Sweden., Wilson G; Jackson Heart Study, School of Public Health, Jackson State University, Jackson, 39213, MS, USA., Xiang YB; State Key Laboratory of Oncogene and Related Genes & Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200000, China., Yao J; The Institute for Translational Genomics and Population Sciences, Division of Genomic Outcomes, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, 90502, CA, USA., Yu C; Department of Occupational and Environmental Health and State Key Laboratory of Environmental Health for Incubating, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430014, China., Yuan JM; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, 15261, PA, USA.; Division of Cancer Control and Population Sciences, UPMC Hillman Cancer, University of Pittsburgh, Pittsburgh, 15232, PA, USA., Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, 48109, MI, USA., Zonderman AB; Behavioral Epidemiology Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, 21224, MD, USA., Becker DM; Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, 21287, MD, USA., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, 48109, MI, USA., Bowden DW; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, 27157, NC, USA., de Faire U; Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, 17177, Sweden., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Psychology, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Elliott P; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, W2 1PG, UK., Esko T; Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Boston, 02142, MA, USA., Freedman BI; Section on Nephrology, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, 27157, NC, USA., Froguel P; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, 59000, France.; Department of Genomics of Common Disease, Imperial College London, London, W12 0NN, UK., Gasparini P; Institute for Maternal and Child Health-IRCCS 'Burlo Garofolo', Trieste, 34137, Italy.; Department of Medical Sciences, University of Trieste, Trieste, 34137, Italy., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, 85764, Germany.; German Center for Diabetes Research (DZD e.V.), Neuherberg, 85764, Germany., Kato N; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, 1628655, Japan., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, 70210, Finland., Lakka TA; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, 70100, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, 70211, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, 70210, Finland., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, 33014, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33014, Finland., Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Stockholm, 17177, Sweden., Oldehinkel AJ; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, 9713 GZ, The Netherlands., Penninx BWJH; Department of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, VU University Medical Center, Amsterdam, 1081 HV, The Netherlands., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, LE3 9PQ, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, LE3 9QD, UK., Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, 37203, TN, USA., van der Harst P; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, 9700 RB, The Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, 1105 AZ, The Netherlands., Van Vliet-Ostaptchouk JV; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, 9713 GZ, The Netherlands., Vollenweider P; Internal Medicine, Department of Medicine, Lausanne University Hospital, Lausanne, 1011, Switzerland., Wagenknecht LE; Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, 27157, NC, USA., Wang YX; Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Ophthalmology and Visual Science Key Lab, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China., Wareham NJ; MRC Epidemiology Unit, University of Cambridge, Cambridge, CB2 0QQ, UK., Weir DR; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, 48104, MI, USA., Wu T; Department of Occupational and Environmental Health and State Key Laboratory of Environmental Health for Incubating, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430014, China., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, 37203, TN, USA., Zhu X; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, 44106, OH, USA., Evans MK; Health Disparities Research Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, 21224, MD, USA., Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Skåne University Hospital, Malmö, 20502, Sweden.; Department of Public Health & Clinical Medicine, Umeå University, Umeå, 90185, Västerbotten, Sweden.; Harvard T. H. Chan School of Public Health, Department of Nutrition, Harvard University, Boston, 02115, MA, USA.; OCDEM, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 7LE, UK., Gudnason V; Icelandic Heart Association, 201, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Horta BL; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, 96020220, RS, Brazil., Kelly TN; Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, 70112, LA, USA., Liu Y; Public Health Sciences, Epidemiology and Prevention, Wake Forest University Health Sciences, Winston-Salem, 27157, NC, USA., North KE; Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, 27514, NC, USA., Pereira AC; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo, 01246903, SP, Brazil., Ridker PM; Preventive Medicine, Brigham and Women's Hospital, Boston, 02215, MA, USA.; Harvard Medical School, Boston, 02131, MA, USA., Tai ES; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, 117549, Singapore.; Health Services and Systems Research, Duke-NUS Medical School, Singapore, 169857, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore., van Dam RM; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, 117549, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore., Fox ER; Cardiology, Medicine, University of Mississippi Medical Center, Jackson, 39216, MS, USA., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, 48109, MI, USA., Liu CT; Biostatistics, Boston University School of Public Health, Boston, 02118, MA, USA., Mook-Kanamori DO; Clinical Epidemiology, Leiden University Medical Center, Leiden, 2300 RC, Netherlands.; Public Health and Primary Care, Leiden University Medical Center, Leiden, 2300 RC, The Netherlands., Province MA; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, 63108, MO, USA., Redline S; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, 02115, MA, USA., van Duijn CM; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CE, The Netherlands., Rotter JI; The Institute for Translational Genomics and Population Sciences, Division of Genomic Outcomes, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, 90502, CA, USA., Kooperberg CB; Fred Hutchinson Cancer Research Center, University of Washington School of Public Health, Seattle, 98109, WA, USA., Gauderman WJ; Biostatistics, Preventive Medicine, University of Southern California, Los Angeles, 90032, CA, USA., Psaty BM; Kaiser Permanente Washington, Health Research Institute, Seattle, 98101, WA, USA.; Cardiovascular Health Research Unit, Epidemiology, Medicine and Health Services, University of Washington, Seattle, 98101, WA, USA., Rice K; Department of Biostatistics, University of Washington, Seattle, 98105, WA, USA., Munroe PB; Clinical Pharmacology, William Harvey Research Instititute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.; NIHR Barts Cardiovascular Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK., Fornage M; Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, 77030, TX, USA., Cupples LA; Biostatistics, Boston University School of Public Health, Boston, 02118, MA, USA.; NHLBI Framingham Heart Study, Framingham, 01702, MA, USA., Rotimi CN; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, 20892, MD, USA., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, 77030, TX, USA., Rao DC; Division of Biostatistics, Washington University School of Medicine, St. Louis, 63110, MO, USA. rao@wustl.edu., Loos RJF; Icahn School of Medicine at Mount Sinai, The Charles Bronfman Institute for Personalized Medicine, New York, 10029, NY, USA. ruth.loos@mssm.edu.; Icahn School of Medicine at Mount Sinai, The Mindich Child Health and Development Institute, New York, 10029, NY, USA. ruth.loos@mssm.edu.
Publikováno v:
Nature communications [Nat Commun] 2019 Jan 22; Vol. 10 (1), pp. 376. Date of Electronic Publication: 2019 Jan 22.
Autor:
Ligthart S; Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CA, the Netherlands., Vaez A; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands; Department of Bioinformatics, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran., Võsa U; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu 51010, Estonia., Stathopoulou MG; Université de Lorraine, INSERM, IGE-PCV, 54000 Nancy, France., de Vries PS; Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CA, the Netherlands; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Prins BP; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK., Van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands., Tanaka T; Translational Gerontology Branch, National Institute on Aging, Baltimore, MD 21224, USA., Naderi E; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands; Department of Radiation Oncology, University of Groningen, University Medical Center Groningen, Groningen 9713 GZ, the Netherlands., Rose LM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA., Wu Y; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA., Karlsson R; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden., Barbalic M; University of Split School of Medicine, Split 21000, Croatia., Lin H; Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA., Pool R; Department of Biological Psychology, Netherlands Twin Register, Vrije Universiteit, Amsterdam 1081 BT, the Netherlands; Amsterdam Public Health research institute, VU University Medical Center, Amsterdam 1081 BT, the Netherlands., Zhu G; QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia., Macé A; Department of Computational Biology, University of Lausanne, Lausanne 1010, Switzerland; Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland; Institute of Social and Preventive Medicine, University Hospital of Lausanne, Lausanne 1010, Switzerland., Sidore C; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche, Sardinia 08045, Italy., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden 2300 RC, the Netherlands; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden 2333 ZA, the Netherlands., Mangino M; Department of Twin Research & Genetic Epidemiology, King's College London, London SE1 7EH, UK; NIHR Biomedical Research Centre at Guy's and St. Thomas' Foundation Trust, London SE1 9RT, UK., Sabater-Lleal M; Unit of Genomics of Complex Diseases, Institut d'Investigació Biomèdica Sant Pau, Barcelona 08025, Spain; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, Stockholm 17176, Sweden., Kemp JP; University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, QLD 4102, Australia; MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol BS8 2BN, UK., Abbasi A; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands; Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen 9713 GZ, the Netherlands; MRC Epidemiology Unit, University of Cambridge School of Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK., Kacprowski T; Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine and Ernst-Moritz-Arndt University Greifswald, Greifswald 17475, Germany; German Centre for Cardiovascular Research, Partner Site Greifswald, Greifswald 17475, Germany., Verweij N; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen 9713 AV, the Netherlands., Smith AV; Icelandic Heart Association, Kopavogur 201, Iceland; Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland., Huang T; Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Marzi C; Institute of Epidemiology II, Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; German Center for Diabetes Research, Partner Site Munich, Munich 85764, Germany., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO 63108-2212, USA., Lohman KK; Department of Epidemiology and Prevention, Public Health Sciences, Wake Forest University Health Sciences, Winston-Salem, NC 27157, USA., Kleber ME; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim 68167, Germany., Milaneschi Y; Department of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, Amsterdam University Medical Center/GGZ inGeest Research & Innovation, Amsterdam 1081 HJ, the Netherlands., Mueller C; Department of General and Interventional Cardiology, University Heart Center Hamburg, Hamburg 20246, Germany; Institute of Medical Biometry and Statistics, University Medical Center Schleswig-Holstein, Campus Luebeck, Lübeck 23562, Germany; German Center for Cardiovascular Research, Partner Site RhineMain, 55131 Mainz, Germany., Huq M; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands., Vlachopoulou E; Transplantation Laboratory, Medicum, University of Helsinki, Helsinki 00014, Finland., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33014, Finland; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere 33520, Finland., Oldmeadow C; Hunter Medical Research Institute, New Lambon Heights, NSW 2305, Australia; Centre for Clinical Epidemiology & Biostatistics, Faculty of Health and Medicine, University of Newcastle, Callaghan, NSW 2308, Australia., Deelen J; Molecular Epidemiology, Leiden University Medical Center, Leiden 2333 ZC, the Netherlands; Max Planck Institute for Biology of Ageing, Cologne 50931, Germany., Perola M; National Institute for Health and Welfare, Helsinki 00271, Finland., Zhao JH; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK., Feenstra B; Department of Epidemiology Research, Statens Serum Institut, Copenhagen 2300, Denmark., Amini M; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands., Lahti J; Helsinki Collegium for Advanced Studies, University of Helsinki, Helsinki 00014, Finland; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki 00014, Finland; Folkhälsan Research Centre, Helsinki 00250, Finland., Schraut KE; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH16 4UX, UK., Fornage M; Human Genetics Center, School of Public Health and Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Suktitipat B; Department of Biochemistry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand., Chen WM; Center for Public Health Genomics, University of Virginia, Charlottesville, VA 22908, USA., Li X; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Nutile T; Institute of Genetics and Biophysics 'A. Buzzati-Traverso,' Consiglio Nazionale delle Ricerche, Napoli 80131, Italy., Malerba G; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona 37134, Italy., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK., Bak T; Interdisciplinary Center Psychopathology and Emotion regulation, University Medical Center Groningen, University of Groningen, Groningen 9700 RB, the Netherlands., Schork N; Human Biology, J. Craig Venter Institute, La Jolla, CA 92037, USA; Quantitative Medicine, Translational Genomics Research Institute, Phoenix, AZ 85004, USA., Del Greco M F; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano 39100, Italy., Thiering E; Institute of Epidemiology, Helmholtz Zentrum München - German Research Centre for Environmental Health, Neuherberg 85764, Germany; Ludwig Maximilian University of Munich, Dr. von Hauner Children's Hospital, Munich 80337, Germany., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Marioni RE; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh EH8 9JZ, UK; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK., Mihailov E; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu 51010, Estonia., Eriksson J; Department of Internal Medicine and Clinical Nutrition, University of Gothenburg, Gothenburg 41345, Sweden., Ozel AB; Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109-5618, USA., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK; Department of Cardiology, Ealing Hospital, Middlesex UB1 3HW, UK., Nethander M; Bioinformatics Core Facility, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 90, Sweden., Cheng YC; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Aslibekyan S; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294-0022, USA., Ang W; Medical School, University of Western Australia, Perth, WA 6009, Australia., Gandin I; AREA Science Park, Trieste 34149, Italy., Yengo L; Centre National de la Recherche Scientifique UMR 8199, University of Lille, Institut Pasteur de Lille, European Genomic Institute for Diabetes, FR 3508, 59000 Lille, France; Program in Complex Trait Genomics, Institute for Molecular Bioscience, University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia., Portas L; Support OU, Institute of Genetic and Biomedic Research, Consiglio Nazionale delle Ricerche, Sassari 7100, Italy., Kooperberg C; Fred Hutchinson Cancer Research Center, Public Health Sciences Division, Mail Stop M3-A410, 1100 Fairview Ave. N., Seattle, WA, USA., Hofer E; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University Graz, Graz 8036, Austria; Institute of Medical Informatics, Statistics and Documentation, Medical University Graz, Graz 8036, Austria., Rajan KB; Department of Internal Medicine, Rush University Medical Center, Chicago, IL 60612, USA., Schurmann C; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., den Hollander W; Department of Medical Statistics and Bio-informatics, Section Molecular Epidemiology, Leiden University Medical Center, Leiden 2333 ZC, the Netherlands., Ahluwalia TS; Steno Diabetes Center Copenhagen, Gentofte 2820, Denmark; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2100, Denmark., Zhao J; Center for Integrative Genomics, School of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA., Draisma HHM; Department of Biological Psychology, Netherlands Twin Register, Vrije Universiteit, Amsterdam 1081 BT, the Netherlands; Amsterdam Public Health research institute, VU University Medical Center, Amsterdam 1081 BT, the Netherlands; Neuroscience Campus Amsterdam, Amsterdam 1081 HV, the Netherlands., Ford I; Robertson Centre for Biostatistics, University of Glasgow, Glasgow G12 8QQ, UK., Timpson N; MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol BS8 2BN, UK., Teumer A; Department SHIP-KEF, Institute for Community Medicine, University Medicine Greifswald, Greifswald 17475, Germany., Huang H; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Wahl S; Institute of Epidemiology II, Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; German Center for Diabetes Research, Partner Site Munich, Munich 85764, Germany., Liu Y; Department of Epidemiology and Prevention, Public Health Sciences, Wake Forest University Health Sciences, Winston-Salem, NC 27157, USA., Huang J; Boston VA Research Institute, Inc., Boston, MA 02130, USA., Uh HW; Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden 2333 ZC, the Netherlands., Geller F; Department of Epidemiology Research, Statens Serum Institut, Copenhagen 2300, Denmark., Joshi PK; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH16 4UX, UK., Yanek LR; GeneSTAR Research Center, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Trabetti E; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona 37134, Italy., Lehne B; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK., Vozzi D; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo,' Trieste 34140, Italy., Verbanck M; Centre National de la Recherche Scientifique UMR 8199, University of Lille, Institut Pasteur de Lille, European Genomic Institute for Diabetes, FR 3508, 59000 Lille, France., Biino G; Institute of Molecular Genetics, Consiglio Nazionale delle Ricerche, Pavia 27100, Italy., Saba Y; Gottfried Schatz Research Center, Institute for Molecular Biology and Biochemistry, 8010 Graz, Austria., Meulenbelt I; Department of Medical Statistics and Bio-informatics, Section Molecular Epidemiology, Leiden University Medical Center, Leiden 2333 ZC, the Netherlands., O'Connell JR; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio 70210, Finland., Giulianini F; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA., Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden., Ballantyne CM; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA; Methodist DeBakey Heart and Vascular Center, Houston, TX 77030, USA., Hottenga JJ; Department of Biological Psychology, Netherlands Twin Register, Vrije Universiteit, Amsterdam 1081 BT, the Netherlands., Montgomery GW; QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia., Rivadineira F; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam 3015 CN, the Netherlands., Rueedi R; Department of Computational Biology, University of Lausanne, Lausanne 1010, Switzerland; Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland., Steri M; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche, Sardinia 08045, Italy., Herzig KH; Department of Physiology, Institute of Biomedicine, University of Oulu, Medical Research Center Oulu and Oulu University Hospital, Oulu 90014, Finland; Biocenter Oulu, University of Oulu, Oulu 90220, Finland; Department of Gastroenterology and Metabolism, Poznan University of Medical Sciences, Poznan 60-512, Poland., Stott DJ; Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow G12 8QQ, UK., Menni C; Department of Twin Research & Genetic Epidemiology, King's College London, London SE1 7EH, UK., Frånberg M; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, Stockholm 17176, Sweden; Department of Numerical Analysis and Computer Science, Stockholm University, Stockholm 100 44, Sweden., St Pourcain B; MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol BS8 2BN, UK; Donders Institute, Radboud University, Nijmegen 6525 XD, the Netherlands., Felix SB; German Centre for Cardiovascular Research, Partner Site Greifswald, Greifswald 17475, Germany; Department for Internal Medicine B, University Medicine Greifswald, Greifswald 17475, Germany., Pers TH; Department of Epidemiology Research, Statens Serum Institut, Copenhagen 2300, Denmark; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2100, Denmark., Bakker SJL; Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen 9713 GZ, the Netherlands., Kraft P; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Peters A; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherber 85764, Germany., Vaidya D; GeneSTAR Research Center, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Delgado G; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim 68167, Germany., Smit JH; Department of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, Amsterdam University Medical Center/GGZ inGeest Research & Innovation, Amsterdam 1081 HJ, the Netherlands., Großmann V; Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University Mainz, Mainz 55131, Germany., Sinisalo J; Heart and Lung Center, Helsinki University Hospital and Helsinki University, Helsinki 00029, Finland., Seppälä I; Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33014, Finland; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere 33520, Finland., Williams SR; Department of Neurology, University of Virginia, Charlottesville, VA 22908, USA., Holliday EG; Hunter Medical Research Institute, New Lambon Heights, NSW 2305, Australia; Centre for Clinical Epidemiology & Biostatistics, Faculty of Health and Medicine, University of Newcastle, Callaghan, NSW 2308, Australia., Moed M; Molecular Epidemiology, Leiden University Medical Center, Leiden 2333 ZC, the Netherlands., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK., Räikkönen K; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki 00014, Finland., Ding J; Department of Internal Medicine/Geriatrics, Wake Forest University Health Sciences, Winston-Salem, NC 27157, USA., Campbell H; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH16 4UX, UK., Sale MM; Center for Public Health Genomics, University of Virginia, Charlottesville, VA 22908, USA., Chen YI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., James AL; Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia; Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia., Ruggiero D; Institute of Genetics and Biophysics 'A. Buzzati-Traverso,' Consiglio Nazionale delle Ricerche, Napoli 80131, Italy; IRCCS Neuromed, Pozzilli (IS) 86077, Italy., Soranzo N; Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SA, UK., Hartman CA; Interdisciplinary Center Psychopathology and Emotion regulation, University Medical Center Groningen, University of Groningen, Groningen 9700 RB, the Netherlands., Smith EN; Department of Pediatrics and Rady Children's Hospital, School of Medicine, University of California, San Diego, La Jolla, CA 92037, USA., Berenson GS; Center for Cardiovascular Health, Tulane University, New Orleans, LA 70112, USA., Fuchsberger C; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano 39100, Italy., Hernandez D; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD 20892, USA., Tiesler CMT; Institute of Epidemiology, Helmholtz Zentrum München - German Research Centre for Environmental Health, Neuherberg 85764, Germany; Ludwig Maximilian University of Munich, Dr. von Hauner Children's Hospital, Munich 80337, Germany., Giedraitis V; Department of Public Health and Caring Sciences, Molecular Geriatrics, Uppsala University, Uppsala 752 37, Sweden., Liewald D; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh EH8 9JZ, UK., Fischer K; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu 51010, Estonia., Mellström D; Department of Internal Medicine and Clinical Nutrition, University of Gothenburg, Gothenburg 41345, Sweden., Larsson A; Department of Medical Sciences, Uppsala University, Uppsala 751 41, Sweden., Wang Y; Department of Medicine, Case Cardiovascular Research Institute, Case Western Reserve University, Harrington Heart & Vascular Institute, University Hospitals, Cleveland, OH 44106, USA., Scott WR; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK., Lorentzon M; Department of Internal Medicine and Clinical Nutrition, University of Gothenburg, Gothenburg 41345, Sweden; Geriatric Medicine, Sahlgrenska University Hospital, Mölndal 431 80, Sweden., Beilby J; PathWest Laboratory Medicine WA, Nedlands, WA 6009, Australia; School of Biomedical Sciences, University of Western Australia, Crawley, Perth, WA 6009, Australia., Ryan KA; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Pennell CE; Medical School, University of Western Australia, Perth, WA 6009, Australia., Vuckovic D; Medical Sciences, Surgical and Health Department, University of Trieste, Trieste 34137, Italy., Balkau B; INSERM U1018, Centre de Recherche en Epidémiologie et Santé des Populations, Team 5 (EpReC, Renal, and Cardiovascular Epidemiology), Université de Versailles Saint-Quentin-en-Yvelines, Université Paris-Saclay, Villejuif 94807, France., Concas MP; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo,' Trieste 34140, Italy., Schmidt R; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University Graz, Graz 8036, Austria., Mendes de Leon CF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA., Bottinger EP; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Kloppenburg M; Department of Rheumatology, Leiden University Medical Center, Leiden 2300 RC, the Netherlands; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden 2333 ZC, the Netherlands., Paternoster L; MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol BS8 2BN, UK., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Musk AW; Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia; Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia., Willemsen G; Department of Biological Psychology, Netherlands Twin Register, Vrije Universiteit, Amsterdam 1081 BT, the Netherlands., Evans DM; University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, QLD 4102, Australia; MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol BS8 2BN, UK., Madden PAF; Department of Psychiatry, Washington University School of Medicine, 4560 Clayton Ave., Suite 1000, St. Louis, MO 63110, USA., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere 33520, Finland; Department of Clinical Physiology, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere 33520, Finland., Kutalik Z; Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland; Institute of Social and Preventive Medicine, University Hospital of Lausanne, Lausanne 1010, Switzerland., Zoledziewska M; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche, Sardinia 08045, Italy., Karhunen V; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, 90014 Oulun yliopisto, Finland., Kritchevsky SB; Gerontology and Geriatric Medicine, Sticht Center on Aging and Rehabilitation, Wake Forest University Health Sciences, Winston-Salem, NC 27157, USA., Sattar N; BHF Glasgow Cardiovascular Research Centre, Faculty of Medicine, Glasgow G12 8TA, UK., Lachance G; Department of Twin Research & Genetic Epidemiology, King's College London, London SE1 7EH, UK., Clarke R; Clinical Trial Service Unit, Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, National Institutes of Health, Bethesda, MD 20892, USA., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku 20520, Finland; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku 20520, Finland., Attia JR; Hunter Medical Research Institute, New Lambon Heights, NSW 2305, Australia; Centre for Clinical Epidemiology & Biostatistics, Faculty of Health and Medicine, University of Newcastle, Callaghan, NSW 2308, Australia; John Hunter Hospital, New Lambton Heights, NWS 2305, Australia., van Heemst D; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden 2333 ZA, the Netherlands., Kajantie E; Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki 00014, Finland; Hospital for Children and Adolescents, Helsinki University Central Hospital and University of Helsinki, Helsinki 00290, Finland; Department of Obstetrics and Gynaecology, MRC Oulu, Oulu University Hospital and University of Oulu, Oulu 90014, Finland., Sorice R; Institute of Genetics and Biophysics 'A. Buzzati-Traverso,' Consiglio Nazionale delle Ricerche, Napoli 80131, Italy., Gambaro G; Division of Nephrology and Dialysis, Columbus-Gemelli University Hospital, Università Cattolica del Sacro Cuore, Roma 168, Italy., Scott RA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK., Hicks AA; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano 39100, Italy., Ferrucci L; Translational Gerontology Branch, National Institute on Aging, Baltimore, MD 21224, USA., Standl M; Institute of Epidemiology, Helmholtz Zentrum München - German Research Centre for Environmental Health, Neuherberg 85764, Germany., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7FZ, UK; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA 02142, USA., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh EH8 9JZ, UK; Alzheimer's Scotland Dementia Research Centre, University of Edinburgh, Edinburgh EH8 9JZ, UK., Karlsson M; Department of Clinical Sciences and Orthopaedic Surgery, Lund University, Malmo 20502, Sweden., Lind L; Department of Medical Sciences, Uppsala University, Uppsala 751 41, Sweden., Li JZ; Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109-5618, USA., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK; Department of Cardiology, Ealing Hospital, Middlesex UB1 3HW, UK; Imperial College Healthcare NHS Trust, London W12 0HS, UK; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 308232, Singapore; MRC-PHE Centre for Environment and Health, Imperial College London, London W2 1PG, UK., Mori TA; Medical School, University of Western Australia, Perth, WA 6009, Australia., de Geus EJCN; Department of Biological Psychology, Netherlands Twin Register, Vrije Universiteit, Amsterdam 1081 BT, the Netherlands; Amsterdam Public Health research institute, VU University Medical Center, Amsterdam 1081 BT, the Netherlands., Heath AC; Department of Psychiatry, Washington University School of Medicine, 4560 Clayton Ave., Suite 1000, St. Louis, MO 63110, USA., Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia., Auvinen J; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, 90014 Oulun yliopisto, Finland; Unit of Primary Health Care, Oulu University Hospital, Oulu 90220, Finland., Buckley BM; Department of Epidemiology and Public Health, University College Cork, Cork T12 K8AF, Ireland., de Craen AJM; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden 2333 ZA, the Netherlands., Waldenberger M; Institute of Epidemiology II, Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; German Center for Cardiovascular Research, Partner Site Munich Heart Alliance, 80636 Munich, Germany., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; Genetic Epidemiology, Institute of Medical Informatics, Biometry, and Epidemiology, Faculty of Medicine, Ludwig Maximilian University of Munich, Neuherberg 85764, Germany., Meitinger T; Institute of Human Genetics, Technische Universität München, Munich 85764, Germany; Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg 85764, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich 81377, Germany., Scott RJ; Hunter Medical Research Institute, New Lambon Heights, NSW 2305, Australia; Information-Based Medicine Stream, Hunter Medical Research Institute, New Lambton Heights, NSW 2305, Australia., McEvoy M; Hunter Medical Research Institute, New Lambon Heights, NSW 2305, Australia; Centre for Clinical Epidemiology & Biostatistics, Faculty of Health and Medicine, University of Newcastle, Callaghan, NSW 2308, Australia., Beekman M; Molecular Epidemiology, Leiden University Medical Center, Leiden 2333 ZC, the Netherlands., Bombieri C; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona 37134, Italy., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Boomsma DI; Department of Biological Psychology, Netherlands Twin Register, Vrije Universiteit, Amsterdam 1081 BT, the Netherlands., Whitfield JB; QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia., Strachan DP; Population Health Research Institute, St. George's, University of London, London SW17 0RE, UK., Hofman A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CA, the Netherlands., Vollenweider P; Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne 1011, Switzerland., Cucca F; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche, Sardinia 08045, Italy., Jarvelin MR; Biocenter Oulu, University of Oulu, Oulu 90220, Finland; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, 90014 Oulun yliopisto, Finland; Unit of Primary Health Care, Oulu University Hospital, Oulu 90220, Finland; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London W2 1PG, UK; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, Kingston Lane, Uxbridge, Middlesex UB8 3PH, UK., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden 2300 RC, the Netherlands; Durrer Center for Cardiogenetic Research, Amsterdam 3501 DG, the Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht 3511 EP, the Netherlands., Spector TD; Department of Twin Research & Genetic Epidemiology, King's College London, London SE1 7EH, UK., Hamsten A; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, Stockholm 17176, Sweden., Zeller T; Department of General and Interventional Cardiology, University Heart Center Hamburg, Hamburg 20246, Germany; German Center for Cardiovascular Research, Partner Site RhineMain, 55131 Mainz, Germany., Uitterlinden AG; Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CA, the Netherlands; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam 3015 CN, the Netherlands., Nauck M; German Centre for Cardiovascular Research, Partner Site Greifswald, Greifswald 17475, Germany; Institute for Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald 17475, Germany., Gudnason V; Icelandic Heart Association, Kopavogur 201, Iceland; Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland., Qi L; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA., Grallert H; Institute of Epidemiology II, Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; German Center for Diabetes Research, Partner Site Munich, Munich 85764, Germany., Borecki IB; Analytical Genetics Group, Regeneron Genetics Center, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA., Rotter JI; Institute for Translational Genomics and Population Sciences, Departments of Pediatrics and Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., März W; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim 68167, Germany; Synlab Academy, Synlab Holding Deutschland GmbH, Mannheim 68161, Germany; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz 8036, Austria., Wild PS; German Center for Cardiovascular Research, Partner Site RhineMain, 55131 Mainz, Germany; Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University Mainz, Mainz 55131, Germany; Preventive Cardiology and Preventive Medicine, Center for Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz 55131, Germany., Lokki ML; Transplantation Laboratory, Medicum, University of Helsinki, Helsinki 00014, Finland., Boyle M; John Hunter Hospital, New Lambton Heights, NWS 2305, Australia., Salomaa V; National Institute for Health and Welfare, Helsinki 00271, Finland., Melbye M; Department of Epidemiology Research, Statens Serum Institut, Copenhagen 2300, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen 2300, Denmark; Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA., Eriksson JG; National Institute for Health and Welfare, Helsinki 00271, Finland; Folkhälsan Research Centre, Helsinki 00250, Finland; Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki 00014, Finland., Wilson JF; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH16 4UX, UK; MRC Human Genetics Unit, Institute for Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK., Penninx BWJH; Department of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, Amsterdam University Medical Center/GGZ inGeest Research & Innovation, Amsterdam 1081 HJ, the Netherlands., Becker DM; GeneSTAR Research Center, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Worrall BB; Departments of Neurology and Public Health Sciences, University of Virginia Charlottesville, Charlottesville, VA 22908-0394, USA., Gibson G; Center for Integrative Genomics, School of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA., Krauss RM; Children's Hospital Oakland Research Institute, Oakland, CA 94609, USA., Ciullo M; Institute of Genetics and Biophysics 'A. Buzzati-Traverso,' Consiglio Nazionale delle Ricerche, Napoli 80131, Italy; IRCCS Neuromed, Pozzilli (IS) 86077, Italy., Zaza G; Renal Unit, Department of Medicine, Verona University Hospital, Verona 37126, Italy., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK., Oldehinkel AJ; Interdisciplinary Center Psychopathology and Emotion regulation, University Medical Center Groningen, University of Groningen, Groningen 9700 RB, the Netherlands., Palmer LJ; School of Public Health, University of Adelaide, Adelaide, SA 5000, Australia., Murray SS; Department of Pathology, University of California, San Diego, San Diego, CA 92121, USA., Pramstaller PP; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano 39100, Italy; General Central Hospital, Department of Neurology, Bolzano 39100, Italy; Department of Neurology, University of Lübeck, Lübeck 23538, Germany., Bandinelli S; Geriatric Unit, Azienda Sanitaria Firenze, Florence 50122, Italy., Heinrich J; Institute of Epidemiology, Helmholtz Zentrum München - German Research Centre for Environmental Health, Neuherberg 85764, Germany; Institute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Comprehensive Pneumology Center Munich, Member DZL, German Center for Lung Research, 81377 Munich, Germany., Ingelsson E; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala 751 41, Sweden; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Stanford Cardiovascular Institute, Stanford University, Stanford, CA 94305, USA., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh EH8 9JZ, UK; Department of Psychology, University of Edinburgh, Edinburgh EH8 9JZ, UK., Mägi R; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu 51010, Estonia., Vandenput L; Department of Internal Medicine and Clinical Nutrition, University of Gothenburg, Gothenburg 41345, Sweden., van der Harst P; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen 9713 AV, the Netherlands., Desch KC; Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI 48109, USA., Kooner JS; Department of Cardiology, Ealing Hospital, Middlesex UB1 3HW, UK; Imperial College Healthcare NHS Trust, London W12 0HS, UK; MRC-PHE Centre for Environment and Health, Imperial College London, London W2 1PG, UK; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK., Ohlsson C; Department of Internal Medicine and Clinical Nutrition, University of Gothenburg, Gothenburg 41345, Sweden., Hayward C; MRC Human Genetics Unit, Institute for Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33014, Finland; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere 33520, Finland., Shuldiner AR; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Arnett DK; University of Kentucky, College of Public Health, Lexington, KY 40508, USA., Beilin LJ; Medical School, University of Western Australia, Perth, WA 6009, Australia., Robino A; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo,' Trieste 34140, Italy., Froguel P; Centre National de la Recherche Scientifique UMR 8199, University of Lille, Institut Pasteur de Lille, European Genomic Institute for Diabetes, FR 3508, 59000 Lille, France; Department of Genomics of Common Disease, School of Public Health, Imperial College London, London SW7 2AZ, UK., Pirastu M; Support OU, Institute of Genetic and Biomedic Research, Consiglio Nazionale delle Ricerche, Sassari 7100, Italy., Jess T; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Frederiksberg 2200, Denmark., Koenig W; German Center for Cardiovascular Research, Partner Site Munich Heart Alliance, 80636 Munich, Germany; Department of Internal Medicine II-Cardiology, University of Ulm Medical Center, 80801 Ulm, Germany; Deutsches Herzzentrum München, Technische Universität München, 80636 Munich, Germany., Loos RJF; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029-6542, USA., Evans DA; Department of Internal Medicine, Rush University Medical Center, Chicago, IL 60612, USA., Schmidt H; Department of Neurology, Medical University Graz, Graz 8010, Austria; Institute of Molecular Biology and Biochemistry, Centre for Molecular Medicine, Medical University of Graz, Graz 8010, Austria., Smith GD; MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol BS8 2BN, UK., Slagboom PE; Molecular Epidemiology, Leiden University Medical Center, Leiden 2333 ZC, the Netherlands., Eiriksdottir G; Icelandic Heart Association, Kopavogur 201, Iceland., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK; Department of Biostatistics, University of Liverpool, Liverpool L69 3GL, UK., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98101, USA; Department of Epidemiology, University of Washington, Seattle, WA 98101, USA; Department of Health Services, University of Washington, Seattle, WA 98195-7660, USA; Kaiser Permanente Washington Health Research Institute, Seattle, WA 98101, USA., Tracy RP; Department of Pathology, University of Vermont, Colchester, VT 05405, USA., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands., Boerwinkle E; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA., Visvikis-Siest S; Université de Lorraine, INSERM, IGE-PCV, 54000 Nancy, France., Reiner AP; Department of Epidemiology, University of Washington, Seattle, WA 98101, USA., Gross M; Department of Lab Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98101, USA., Franke L; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands., Franco OH; Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CA, the Netherlands; Institute of Social and Preventive Medicine, University of Bern, 3012 Bern, Switzerland., Benjamin EJ; Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA; National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA 01702, USA., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA., Dupuis J; National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA 01702, USA; Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands., Dehghan A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CA, the Netherlands; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London W2 1PG, UK. Electronic address: a.dehghan@imperial.ac.uk., Alizadeh BZ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands. Electronic address: b.z.alizadeh@umcg.nl.
Publikováno v:
American journal of human genetics [Am J Hum Genet] 2018 Nov 01; Vol. 103 (5), pp. 691-706.
Autor:
Kraja AT, Cook JP, Warren HR, Surendran P, Liu C, Evangelou E, Manning AK, Grarup N, Drenos F, Sim X, Smith AV, Amin N, Blakemore AIF, Bork-Jensen J, Brandslund I, Farmaki AE, Fava C, Ferreira T, Herzig KH, Giri A, Giulianini F, Grove ML, Guo X, Harris SE, Have CT, Havulinna AS, Zhang H, Jørgensen ME, Käräjämäki A, Kooperberg C, Linneberg A, Little L, Liu Y, Bonnycastle LL, Lu Y, Mägi R, Mahajan A, Malerba G, Marioni RE, Mei H, Menni C, Morrison AC, Padmanabhan S, Palmas W, Poveda A, Rauramaa R, Rayner NW, Riaz M, Rice K, Richard MA, Smith JA, Southam L, Stančáková A, Stirrups KE, Tragante V, Tuomi T, Tzoulaki I, Varga TV, Weiss S, Yiorkas AM, Young R, Zhang W, Barnes MR, Cabrera CP, Gao H, Boehnke M, Boerwinkle E, Chambers JC, Connell JM, Christensen CK, de Boer RA, Deary IJ, Dedoussis G, Deloukas P, Dominiczak AF, Dörr M, Joehanes R, Edwards TL, Esko T, Fornage M, Franceschini N, Franks PW, Gambaro G, Groop L, Hallmans G, Hansen T, Hayward C, Heikki O, Ingelsson E, Tuomilehto J, Jarvelin MR, Kardia SLR, Karpe F, Kooner JS, Lakka TA, Langenberg C, Lind L, Loos RJF, Laakso M, McCarthy MI, Melander O, Mohlke KL, Morris AP, Palmer CNA, Pedersen O, Polasek O, Poulter NR, Province MA, Psaty BM, Ridker PM, Rotter JI, Rudan I, Salomaa V, Samani NJ, Sever PJ, Skaaby T, Stafford JM, Starr JM, van der Harst P, van der Meer P, van Duijn CM, Vergnaud AC, Gudnason V, Wareham NJ, Wilson JG, Willer CJ, Witte DR, Zeggini E, Saleheen D, Butterworth AS, Danesh J, Asselbergs FW, Wain LV, Ehret GB, Chasman DI, Caulfield MJ, Elliott P, Lindgren CM, Levy D, Newton-Cheh C, Munroe PB, Howson JMM
Publikováno v:
Circulation. Cardiovascular genetics [Circ Cardiovasc Genet] 2017 Oct; Vol. 10 (5).
Autor:
Graff M; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., North KE; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.; Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, NC, USA., Richardson AS; RAND Corporation, Santa Monica, CA, USA., Young KL; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.; Carolina Population Center, University of North Carolina, Chapel Hill, NC, USA., Mazul AL; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Highland HM; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Mohlke KL; Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, NC, USA.; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Lange LA; Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, NC, USA.; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Lange EM; Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, NC, USA.; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Mullan Harris K; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA.; Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, NC, USA.; Department of Sociology, University of North Carolina, Chapel Hill, NC, USA., Gordon-Larsen P; Carolina Population Center, University of North Carolina, Chapel Hill, NC, USA.; Department of Nutrition, Gillings School of Global Public Health, School of Medicine, University of North Carolina, Chapel Hill, NC, USA.
Publikováno v:
International journal of obesity (2005) [Int J Obes (Lond)] 2017 May; Vol. 41 (5), pp. 759-768. Date of Electronic Publication: 2016 Dec 27.
Autor:
Schick UM; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98195, USA; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Jain D; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Hodonsky CJ; Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27514, USA., Morrison JV; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Davis JP; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA., Brown L; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Sofer T; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Conomos MP; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Schurmann C; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., McHugh CP; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Nelson SC; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Vadlamudi S; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA., Stilp A; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Plantinga A; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Baier L; Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Disease, NIH, 445 North 5(th) Street, Phoenix, AZ 85004, USA., Bien SA; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98195, USA., Gogarten SM; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Laurie CA; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Taylor KD; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center, Torrance, CA 90502, USA; Department of Pediatrics, Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Liu Y; School of Medicine, Wake Forest University, Winston-Salem, NC 27157, USA., Auer PL; Joseph J. Zilber School of Public Health, University of Wisconsin Milwaukee, Milwaukee, WI 53201, USA., Franceschini N; Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27514, USA., Szpiro A; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Rice K; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Kerr KF; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Rotter JI; Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute, Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Hanson RL; Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Disease, NIH, 445 North 5(th) Street, Phoenix, AZ 85004, USA., Papanicolaou G; Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USA., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, VA 22908, USA; Division of Endocrinology, Department of Medicine, University of Virginia, Charlottesville, VA 22908, USA., Loos RJ; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Browning BL; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Browning SR; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Weir BS; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Laurie CC; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA., North KE; Department of Epidemiology, University of North Carolina, Chapel Hill, NC 27514, USA., Thornton TA; Department of Biostatistics, University of Washington, Seattle, WA 98195, USA., Reiner AP; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98195, USA. Electronic address: apreiner@uw.edu.
Publikováno v:
American journal of human genetics [Am J Hum Genet] 2016 Feb 04; Vol. 98 (2), pp. 229-42. Date of Electronic Publication: 2016 Jan 21.
Autor:
Gaulton KJ; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Genetics, Stanford University, Stanford, California, USA., Ferreira T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Lee Y; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Raimondo A; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Mägi R; Estonian Genome Center, University of Tartu, Tartu, Estonia., Reschen ME; Centre for Cellular and Molecular Physiology, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Locke A; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Rayner NW; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.; Wellcome Trust Sanger Institute, Hinxton, UK., Robertson N; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Scott RA; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., Prokopenko I; Genomics of Common Disease, Imperial College London, London, UK., Scott LJ; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Green T; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Sparso T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Thuillier D; Lille Institute of Biology, European Genomics Institute of Diabetes, Lille, France., Yengo L; Lille Institute of Biology, European Genomics Institute of Diabetes, Lille, France., Grallert H; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Wahl S; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Frånberg M; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Science for Life Laboratory, Stockholm, Sweden.; Department for Numerical Analysis and Computer Science, Stockholm University, Stockholm, Sweden., Strawbridge RJ; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Kestler H; Leibniz Institute for Age Research, Fritz Lipmann Institute, Jena, Germany.; Medical Systems Biology, Ulm University, Ulm, Germany., Chheda H; Finnish Institute for Molecular Medicine (FIMM), Helsinki, Finland., Eisele L; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany., Gustafsson S; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Steinthorsdottir V; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Thorleifsson G; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Qi L; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana, USA., Karssen LC; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., van Leeuwen EM; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Willems SM; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK.; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Li M; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA., Chen H; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.; Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, USA., Fuchsberger C; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Kwan P; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Ma C; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Linderman M; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Lu Y; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Thomsen SK; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Rundle JK; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Beer NL; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., van de Bunt M; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Chalisey A; Centre for Cellular and Molecular Physiology, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Kang HM; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Voight BF; Department of Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Abecasis GR; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Almgren P; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden., Baldassarre D; Centro Cardiologico Monzino, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milan, Italy.; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy., Balkau B; INSERM Centre de Recherche Epidémiologie et Santé des Populations (CESP) U1018, Villejuif, France.; University Paris Sud 11, UMRS 1018, Villejuif, France., Benediktsson R; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Landspitali University Hospital, Reykjavik, Iceland., Blüher M; Integrated Treatment and Research (IFB) Center for Adiposity Diseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Boeing H; German Institute of Human Nutrition, Potsdam-Rehbruecke, Germany., Bonnycastle LL; National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA., Bottinger EP; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Burtt NP; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Carey J; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Charpentier G; Endocrinology-Diabetology Unit, Corbeil-Essonnes Hospital, Corbeil-Essonnes, France., Chines PS; National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA., Cornelis MC; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Couper DJ; Collaborative Studies Coordinating Center, Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Crenshaw AT; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., van Dam RM; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore., Doney AS; Diabetes Research Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee, UK.; Pharmacogenomics Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee, UK., Dorkhan M; Lund University Diabetes Centre, Department of Clinical Science Malmo, Novo Nordisk Scandinavia, Malmo, Sweden., Edkins S; Wellcome Trust Sanger Institute, Hinxton, UK., Eriksson JG; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.; Unit of General Practice, Helsinki University General Hospital, Helsinki, Finland.; Folkhalsan Research Center, Helsinki, Finland., Esko T; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Division of Endocrinology, Children's Hospital, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Eury E; CNRS UMR 8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille, France., Fadista J; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden., Flannick J; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Fontanillas P; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Fox C; National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts, USA.; Division of Endocrinology and Metabolism, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Franks PW; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA.; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden.; Department of Clinical Sciences, Lund University, Malmo, Sweden.; Department of Public Health and Clinical Medicine, Umea University, Umea, Sweden., Gertow K; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Gigante B; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Gottesman O; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Grant GB; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Groves CJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Hassinen M; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Have CT; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Herder C; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Dusseldorf, Dusseldorf, Germany.; German Center for Diabetes Research, partner site Dusseldorf, Dusseldorf, Germany., Holmen OL; Nord-Trøndelag Health Study (HUNT) Research Center, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway., Hreidarsson AB; Landspitali University Hospital, Reykjavik, Iceland., Humphries SE; Cardiovascular Genetics, British Heart Foundation (BHF) Laboratories, Institute of Cardiovascular Sciences, University College London, London, UK., Hunter DJ; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard School of Public Health, Boston, Massachusetts, USA., Jackson AU; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Jonsson A; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden., Jørgensen ME; Steno Diabetes Center, Gentofte, Denmark., Jørgensen T; Research Centre for Prevention and Health, Capital Region of Denmark, Copenhagen, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Faculty of Medicine, University of Aalborg, Aalborg, Denmark., Kao WH; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA., Kerrison ND; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., Kinnunen L; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland., Klopp N; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Hannover Unified Biobank, Hannover Medical School, Hannover, Germany., Kong A; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Kovacs P; Integrated Treatment and Research (IFB) Center for Adiposity Diseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Kraft P; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.; Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard School of Public Health, Boston, Massachusetts, USA., Kravic J; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden., Langford C; Wellcome Trust Sanger Institute, Hinxton, UK., Leander K; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Liang L; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.; Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, USA., Lichtner P; Institute of Human Genetics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Lindholm E; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden., Linneberg A; Research Centre for Prevention and Health, Capital Region of Denmark, Copenhagen, Denmark.; Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA., Lobbens S; CNRS UMR 8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille, France., Luan J; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., Lyssenko V; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden.; Steno Diabetes Center, Gentofte, Denmark., Männistö S; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland., McLeod O; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Meyer J; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Mihailov E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Mirza G; Biomedical Research Centre Genomics Core Facility, Guy's and St Thomas' National Health Service (NHS) Foundation Trust, Guy's &St Thomas' Hospital, London, UK., Mühleisen TW; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany.; Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, Jülich, Germany., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, University Hospital Grosshadern, Ludwig Maximilians Universität, Munich, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig Maximilians Universität, Neuherberg, Germany.; DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany., Navarro C; Department of Epidemiology, Murcia Regional Health Council, Instituto Murciano de Investigación Biosanitaria Virgen de la Arrixaca (IMIB-Arrixaca), Murcia, Spain.; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.; Department of Health and Social Sciences, Universidad de Murcia, Murcia, Spain., Nöthen MM; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Department of Genomics, Life and Brain Center, University of Bonn, Bonn, Germany., Oskolkov NN; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden., Owen KR; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.; Oxford National Institute for Health Research Biomedical Research Centre, Churchill Hospital, Oxford, UK., Palli D; Cancer Research and Prevention Institute (ISPO), Florence, Italy., Pechlivanis S; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany., Peltonen L; Wellcome Trust Sanger Institute, Hinxton, UK.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Finnish Institute for Molecular Medicine (FIMM), Helsinki, Finland.; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland., Perry JR; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., Platou CG; Nord-Trøndelag Health Study (HUNT) Research Center, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway.; Department of Internal Medicine, Levanger Hospital, Nord-Trondelag Health Trust, Levanger, Norway., Roden M; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Dusseldorf, Dusseldorf, Germany.; German Center for Diabetes Research, partner site Dusseldorf, Dusseldorf, Germany.; Department of Endocrinology and Diabetology, University Hospital Dusseldorf, Dusseldorf, Germany., Ruderfer D; Division of Psychiatric Genomics, Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Rybin D; Boston University Data Coordinating Center, Boston, Massachusetts, USA., van der Schouw YT; University Medical Center Utrecht, Utrecht, the Netherlands., Sennblad B; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Science for Life Laboratory, Stockholm, Sweden., Sigurðsson G; Landspitali University Hospital, Reykjavik, Iceland.; Icelandic Heart Association, Kopavogur, Iceland., Stančáková A; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Steinbach G; Department of Clinical Chemistry and Central Laboratory, University of Ulm, Ulm, Germany., Storm P; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig Maximilians Universität, Neuherberg, Germany., Stringham HM; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Sun Q; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Thorand B; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Tikkanen E; Finnish Institute for Molecular Medicine (FIMM), Helsinki, Finland.; Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki, Finland., Tonjes A; Integrated Treatment and Research (IFB) Center for Adiposity Diseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Trakalo J; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Tremoli E; Centro Cardiologico Monzino, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milan, Italy.; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy., Tuomi T; Finnish Institute for Molecular Medicine (FIMM), Helsinki, Finland.; Folkhalsan Research Center, Helsinki, Finland.; Department of Endocrinology, Abdominal Center, Helsinki University Hospital, Helsinki, Finland.; Research Program for Diabetes and Obesity, University of Helsinki, Helsinki, Finland., Wennauer R; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Wiltshire S; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Wood AR; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Zeggini E; Wellcome Trust Sanger Institute, Hinxton, UK., Dunham I; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, UK., Birney E; European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, UK., Pasquali L; Division of Endocrinology, Germans Trias i Pujol University Hospital and Research Institute, Badalona, Spain.; Josep Carreras Leukaemia Research Institute, Badalona, Spain.; CIBER de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), Barcelona, Spain., Ferrer J; Department of Medicine, Imperial College London, London, UK.; Institut d'Investigacions Biomèdiques August Pi i Sunyer, Centre Esther Koplowitz, Barcelona, Spain., Loos RJ; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK.; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Dupuis J; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.; National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts, USA., Florez JC; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.; Diabetes Research Center, Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts, USA., Boerwinkle E; Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas, USA.; Human Genome Sequencing Center at Baylor College of Medicine, Houston, Texas, USA., Pankow JS; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, Minnesota, USA., van Duijn C; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Netherlands Genomics Initiative, Netherlands Consortium for Healthy Ageing and Center for Medical Systems Biology, Rotterdam, the Netherlands., Sijbrands E; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Meigs JB; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.; General Medicine Division, Massachusetts General Hospital, Boston, Massachusetts, USA., Hu FB; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Thorsteinsdottir U; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Stefansson K; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Lakka TA; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Rauramaa R; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Stumvoll M; Integrated Treatment and Research (IFB) Center for Adiposity Diseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Lind L; Department of Medical Sciences, Uppsala University Hospital, Uppsala, Sweden., Keinanen-Kiukaanniemi SM; Faculty of Medicine, Institute of Health Sciences, University of Oulu, Oulu, Finland.; Unit of General Practice, Oulu University Hospital, Oulu, Finland., Korpi-Hyövälti E; South Ostrobothnia Central Hospital, Seinajoki, Finland., Saaristo TE; Finnish Diabetes Association, Tampere, Finland.; Pirkanmaa District Hospital, Tampere, Finland., Saltevo J; Department of Medicine, Central Finland Central Hospital, Jyvasklya, Finland., Kuusisto J; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Laakso M; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia., Erbel R; Clinic of Cardiology, West German Heart Centre, University Hospital of Essen, University Duisdurg-Essen, Essen, Germany., Jöcke KH; Institute of Biomedicine/Physiology, University of Eastern Finland, Kuopio, Finland., Moebus S; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany., Ripatti S; Wellcome Trust Sanger Institute, Hinxton, UK.; Finnish Institute for Molecular Medicine (FIMM), Helsinki, Finland.; Department of Public Health, Hjelt Institute, University of Helsinki, Helsinki, Finland.; Public Health Genomics Unit, National Institute for Health and Welfare, Helsinki, Finland., Salomaa V; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland., Ingelsson E; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Boehm BO; Division of Endocrinology and Diabetes, Department of Internal Medicine, University Medical Centre Ulm, Ulm, Germany.; Lee Kong Chian School of Medicine, Imperial College London and Nanyang Technological University, Singapore., Bergman RN; Diabetes and Obesity Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA., Collins FS; National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA., Mohlke KL; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Koistinen H; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.; Division of Endocrinology, Department of Medicine, Helsinki University Central Hospital, Helsinki, Finland.; Minerva Foundation Institute for Medical Research, Helsinki, Finland., Tuomilehto J; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.; Instituto de Investigación Sanitaria del Hospital Universitario La Paz, Madrid, Spain.; Centre for Vascular Prevention, Danube University Krems, Krems, Austria.; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Hveem K; Nord-Trøndelag Health Study (HUNT) Research Center, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway., Njølstad I; Department of Community Medicine, Faculty of Health Sciences, University of Tromso, Tromso, Norway., Deloukas P; Wellcome Trust Sanger Institute, Hinxton, UK.; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Donnelly PJ; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Statistics, University of Oxford, Oxford, UK., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Hattersley AT; Institute of Biomedical and Clinical Science, University of Exeter Medical School, Exeter, UK., de Faire U; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Hamsten A; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Illig T; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Hannover Unified Biobank, Hannover Medical School, Hannover, Germany., Peters A; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research, Neuherberg, Germany.; DZHK (German Center for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany., Cauchi S; Lille Institute of Biology, European Genomics Institute of Diabetes, Lille, France., Sladek R; Montreal Diabetes Research Center, Centre de Recherche du Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.; McGill University and Génome Québec Innovation Centre, Montreal, Quebec, Canada., Froguel P; Genomics of Common Disease, Imperial College London, London, UK.; Lille Institute of Biology, European Genomics Institute of Diabetes, Lille, France.; CNRS UMR 8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille, France., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Faculty of Health Sciences, University of Southern Denmark, Odense, Denmark., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Morris AD; Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Palmer CN; Diabetes Research Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee, UK.; Pharmacogenomics Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee, UK., Kathiresan S; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA., Melander O; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden., Nilsson PM; 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Centre for Cellular and Molecular Physiology, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Gloyn AL; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.; Oxford National Institute for Health Research Biomedical Research Centre, Churchill Hospital, Oxford, UK., Altshuler D; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA.; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.; Diabetes Research Center, Diabetes Unit, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.; Department of Molecular Biology, Harvard Medical School, Boston, Massachusetts, USA., Boehnke M; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Teslovich TM; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., McCarthy MI; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.; Oxford National Institute for Health Research Biomedical Research Centre, Churchill Hospital, Oxford, UK., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Department of Biostatistics, University of Liverpool, Liverpool, UK.; Department of Molecular and Clinical Pharmacology, University of Liverpool, Liverpool, UK.
Publikováno v:
Nature genetics [Nat Genet] 2015 Dec; Vol. 47 (12), pp. 1415-25. Date of Electronic Publication: 2015 Nov 09.
Autor:
Young KL; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA. kristin.young@unc.edu.; Carolina Population Center, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA. kristin.young@unc.edu.; 137 East Franklin Street, Suite 306, Chapel Hill, NC, 27514, USA. kristin.young@unc.edu., Graff M; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA. migraff@email.unc.edu.; Carolina Population Center, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA. migraff@email.unc.edu., North KE; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA. karinorth@unc.edu.; Carolina Center for Genome Sciences, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA. karinorth@unc.edu., Richardson AS; Carolina Population Center, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA. anno.richardson@gmail.com.; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA. anno.richardson@gmail.com., Mohlke KL; Carolina Center for Genome Sciences, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA. karen_mohlke@med.unc.edu.; Department of Genetics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA. karen_mohlke@med.unc.edu., Lange LA; Carolina Center for Genome Sciences, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA. leslie_lange@med.unc.edu.; Department of Genetics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA. leslie_lange@med.unc.edu., Lange EM; Carolina Center for Genome Sciences, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA. ethan_lange@med.unc.edu.; Department of Genetics, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA. ethan_lange@med.unc.edu., Harris KM; Carolina Population Center, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA. kathie_harris@unc.edu.; Department of Sociology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA. kathie_harris@unc.edu., Gordon-Larsen P; Carolina Population Center, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA. pglarsen@unc.edu.; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA. pglarsen@unc.edu.
Publikováno v:
BMC genetics [BMC Genet] 2015 Nov 04; Vol. 16, pp. 131. Date of Electronic Publication: 2015 Nov 04.
Autor:
Kato N; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan., Loh M; Institute of Health Sciences, University of Oulu, Oulu, Finland.; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research (ASTAR), Singapore., Takeuchi F; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan., Verweij N; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Wang X; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK., Kelly TN; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA., Saleheen D; Center for Non-Communicable Diseases, Karachi, Pakistan.; Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK.; Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Lehne B; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Leach IM; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Drong AW; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Abbott J; Bioinformatics Support Service, Imperial College London, London, UK., Wahl S; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Tan ST; Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK.; National Heart and Lung Institute, Imperial College London, London, UK., Scott WR; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK., Campanella G; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Chadeau-Hyam M; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Afzal U; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK., Ahluwalia TS; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Copenhagen Prospective Studies on Asthma in Childhood (COSPAC), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.; Steno Diabetes Center, Gentofte, Denmark., Bonder MJ; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Chen P; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore., Dehghan A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Edwards TL; Vanderbilt Epidemiology Center, Center for Human Genetics Research, Division of Epidemiology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA., Esko T; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Division of Endocrinology, Children's Hospital Boston, Boston, Massachusetts, USA.; Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA., Go MJ; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea., Harris SE; Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine and Medical Research Council (MRC) Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK.; Centre for Cognitive Aging and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Hartiala J; Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California, USA.; Institute for Genetic Medicine, University of Southern California Keck School of Medicine, Los Angeles, California, USA., Kasela S; Estonian Genome Center, University of Tartu, Tartu, Estonia., Kasturiratne A; Department of Public Health, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka., Khor CC; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.; Genome Institute of Singapore, ASTAR, Singapore.; Department of Ophthalmology, National University of Singapore, Singapore.; Department of Paediatrics, National University of Singapore, Singapore., Kleber ME; Medical Clinic V, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany., Li H; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China., Yu Mok Z; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Nakatochi M; Center for Advanced Medicine and Clinical Research, Nagoya University Hospital, Nagoya, Japan., Sapari NS; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Saxena R; Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Stewart AFR; University of Ottawa Heart Institute, Cardiovascular Research Methods Centre, Ottawa, Ontario, Canada.; Ruddy Canadian Cardiovascular Genetics Centre, Ottawa, Ontario, Canada., Stolk L; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Tabara Y; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan., Teh AL; Singapore Institute for Clinical Sciences (SICS), ASTAR, Singapore., Wu Y; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA., Wu JY; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.; School of Chinese Medicine, China Medical University, Taichung, Taiwan., Zhang Y; State Key Laboratory of Medical Genetics, Shanghai Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Institute of Hypertension, Shanghai, China., Aits I; Institute of Epidemiology and Biobank popgen, Christian Albrechts University of Kiel, Kiel, Germany., Da Silva Couto Alves A; Department of Epidemiology and Biostatistics, MRC Health Protection Agency (PHE) Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Das S; Department of Epidemiology and Biostatistics, MRC Health Protection Agency (PHE) Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Dorajoo R; Genome Institute of Singapore, ASTAR, Singapore., Hopewell JC; Clinical Trials Support Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK., Kim YK; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea., Koivula RW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö, Sweden., Luan J; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere, Finland., Nguyen QN; Vietnam National Heart Institute, Bach Mai Hospital, Hanoi, Vietnam., Pereira MA; School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA., Postmus I; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands.; Netherlands Consortium for Healthy Ageing, Leiden, the Netherlands., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Scannell Bryan M; Department of Public Health Sciences, University of Chicago, Chicago, Illinois, USA., Scott RA; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Sorice R; Institute of Genetics and Biophysics A Buzzati-Traverso, CNR, Naples, Italy., Tragante V; Division of Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands., Traglia M; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy.; Institute for Maternal and Child Health, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) 'Burlo Garofolo', Trieste, Italy., White J; University College London Genetics Institute, Department of Genetics, Environment and Evolution, University College London, London, UK., Yamamoto K; Division of Genomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan., Zhang Y; Department of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China., Adair LS; Department of Nutrition, University of North Carolina, Chapel Hill, North Carolina, USA., Ahmed A; UChicago Research Bangladesh, Uttara, Dhaka, Bangladesh., Akiyama K; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan., Asif R; Center for Non-Communicable Diseases, Karachi, Pakistan., Aung T; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore., Barroso I; Metabolic Disease Group, Wellcome Trust Sanger Institute, Cambridge, UK.; National Institute for Health Research (NIHR) Cambridge Biomedical Research Centre, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.; University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Bjonnes A; Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Braun TR; Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA., Cai H; Vanderbilt Epidemiology Center, Division of Epidemiology, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, Tennessee, USA.; Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA., Chang LC; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan., Chen CH; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.; School of Chinese Medicine, China Medical University, Taichung, Taiwan., Cheng CY; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.; Department of Ophthalmology, National University of Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Centre for Quantitative Medicine, Office of Clinical Sciences, Duke-National University of Singapore Graduate Medical School, Singapore., Chong YS; Singapore Institute for Clinical Sciences (SICS), ASTAR, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Collins R; Clinical Trials Support Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK., Courtney R; Vanderbilt Epidemiology Center, Division of Epidemiology, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, Tennessee, USA.; Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA., Davies G; Centre for Cognitive Aging and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Delgado G; Medical Clinic V, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany., Do LD; Vietnam National Heart Institute, Bach Mai Hospital, Hanoi, Vietnam., Doevendans PA; Division of Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands., Gansevoort RT; Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Gao YT; Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China., Grammer TB; Medical Clinic V, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany., Grarup N; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Grewal J; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK., Gu D; Fu Wai Hospital and Cardiovascular Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China., Wander GS; Dayanand Medical College and Hospital Unit, Hero DMC Heart Institute, Ludhiana, India., Hartikainen AL; Department of Obstetrics and Gynecology, Oulu University Hospital, Oulu, Finland.; Medical Research Center, University of Oulu, Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland., Hazen SL; Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio, USA.; Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA., He J; Department of Biostatistics, Vanderbilt University, Nashville, Tennessee, USA., Heng CK; Department of Paediatrics, Yong Loo Lin School of Medicine, Singapore., Hixson JE; Human Genetics Center, University of Texas School of Public Health at Houston, Houston, Texas, USA., Hofman A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Hsu C; University of Southern California Keck School of Medicine, Los Angeles, California, USA., Huang W; Department of Genetics, Chinese National Human Genomic Center, Shanghai, China., Husemoen LLN; Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark., Hwang JY; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea., Ichihara S; Graduate School of Regional Innovation Studies, Mie University, Tsu, Japan., Igase M; Department of Geriatric Medicine, Ehime University Graduate School of Medicine, Toon, Ehime, Japan., Isono M; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan., Justesen JM; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Katsuya T; Department of Clinical Gene Therapy, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Suita, Japan., Kibriya MG; Department of Public Health Sciences, University of Chicago, Chicago, Illinois, USA., Kim YJ; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea., Kishimoto M; National Center for Global Health and Medicine, Toyama, Japan., Koh WP; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.; Duke-National University of Singapore Graduate Medical School, Singapore., Kohara K; Department of Geriatric Medicine, Ehime University Graduate School of Medicine, Toon, Ehime, Japan., Kumari M; Department of Epidemiology and Public Health, University College London, London, UK., Kwek K; K.K. Women's and Children's Hospital, Singapore., Lee NR; University of San Carlos Office of Population Studies Foundation, University of San Carlos, Cebu City, Philippines.; Department of Anthropology, Sociology and History, University of San Carlos, Cebu City, Philippines., Lee J; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore., Liao J; Department of Ophthalmology, National University of Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore., Lieb W; Institute of Epidemiology and Biobank popgen, Christian Albrechts University of Kiel, Kiel, Germany., Liewald DCM; Centre for Cognitive Aging and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Matsubara T; Department of Internal Medicine, Aichi-Gakuin University School of Dentistry, Nagoya, Japan., Matsushita Y; National Center for Global Health and Medicine, Toyama, Japan., Meitinger T; Institute of Human Genetics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, Technische Universität München, Munich, Germany., Mihailov E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Milani L; Estonian Genome Center, University of Tartu, Tartu, Estonia., Mills R; Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK., Mononen N; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere, Finland., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, Ludwig Maximilians University Munich, Munich, Germany.; German Center for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany., Nabika T; Department of Functional Pathology, Shimane University Faculty of Medicine, Izumo, Japan., Nakashima E; Division of Endocrinology and Diabetes, Department of Internal Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.; Department of Diabetes and Endocrinology, Chubu Rosai Hospital, Nagoya, Japan., Ng HK; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Nikus K; Heart Centre, Department of Cardiology, Tampere University Hospital and University of Tampere School of Medicine, Tampere, Finland., Nutile T; Institute of Genetics and Biophysics A Buzzati-Traverso, CNR, Naples, Italy., Ohkubo T; Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan., Ohnaka K; Department of Geriatric Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Parish S; Clinical Trials Support Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK., Paternoster L; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Peng H; Department of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China., Peters A; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany., Pham ST; Vietnam National Heart Institute, Bach Mai Hospital, Hanoi, Vietnam., Pinidiyapathirage MJ; Department of Public Health, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka., Rahman M; UChicago Research Bangladesh, Uttara, Dhaka, Bangladesh.; Research and Evaluation Division, Bangladesh Rehabilitation Assistance Committee (BRAC), Dhaka, Bangladesh., Rakugi H; Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Suita, Japan., Rolandsson O; Department of Public Health and Clinical Medicine, Section for Family Medicine, Umeå Universitet, Umeå, Sweden., Ann Rozario M; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Ruggiero D; Institute of Genetics and Biophysics A Buzzati-Traverso, CNR, Naples, Italy., Sala CF; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Sarju R; Dayanand Medical College and Hospital Unit, Hero DMC Heart Institute, Ludhiana, India., Shimokawa K; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Sparsø T; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Spiering W; Department of Vascular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands., Starr JM; Centre for Cognitive Aging and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK., Stott DJ; Academic Section of Geriatric Medicine, Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow, UK., Stram DO; University of Southern California Keck School of Medicine, Los Angeles, California, USA., Sugiyama T; Institute for Adult Diseases, Asahi Life Foundation, Tokyo, Japan., Szymczak S; Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany., Tang WHW; Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio, USA.; Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA., Tong L; Department of Public Health Sciences, University of Chicago, Chicago, Illinois, USA., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., Turjanmaa V; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland.; Department of Clinical Physiology, University of Tampere School of Medicine, Tampere, Finland., Ueshima H; Department of Health Science, Shiga University of Medical Science, Otsu, Japan.; Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Otsu, Japan., Uitterlinden AG; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Umemura S; Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan., Vaarasmaki M; Department of Obstetrics and Gynecology, Oulu University Hospital, Oulu, Finland.; Medical Research Center, University of Oulu, Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland., van Dam RM; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore., van Gilst WH; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., van Veldhuisen DJ; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Viikari JS; Division of Medicine, Turku University Hospital, Turku, Finland.; 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Publikováno v:
Nature genetics [Nat Genet] 2015 Nov; Vol. 47 (11), pp. 1282-1293. Date of Electronic Publication: 2015 Sep 21.
Autor:
Buchkovich ML; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA. buchkovm@email.unc.edu., Eklund K; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA. keklund@email.unc.edu., Duan Q; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA. qduan@email.unc.edu., Li Y; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA. yunli@med.unc.edu.; Department of Biostatistics, University of North Carolina, Chapel Hill, NC, 27599, USA. yunli@med.unc.edu.; Department of Computer Science, University of North Carolina, Chapel Hill, NC, 27599, USA. yunli@med.unc.edu., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA. karen_mohlke@med.unc.edu., Furey TS; Department of Genetics, University of North Carolina, Chapel Hill, NC, 27599, USA. tsfurey@email.unc.edu.; Department of Biology, University of North Carolina, Chapel Hill, NC, 27599, USA. tsfurey@email.unc.edu.
Publikováno v:
BMC medical genomics [BMC Med Genomics] 2015 Jul 26; Vol. 8, pp. 43. Date of Electronic Publication: 2015 Jul 26.