Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Gottesman O"'
Autor:
Nielsen JB; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI 48109, USA; Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Fritsche LG; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger 7600, Norway; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim 7491, Norway., Zhou W; Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Teslovich TM; Regeneron Genetics Center, Tarrytown, NY 10591, USA., Holmen OL; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger 7600, Norway; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim 7491, Norway; Department of Cardiology, St. Olav's University Hospital, Trondheim 7030, Norway., Gustafsson S; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala 75237, Sweden., Gabrielsen ME; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger 7600, Norway; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim 7491, Norway., Schmidt EM; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Beaumont R; Royal Devon & Exeter NHS Foundation Trust and University of Exeter Barrack Road Exeter, Exeter EX2 5WD, UK., Wolford BN; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI 48109, USA; Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Lin M; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI 48109, USA; Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Brummett CM; Department of Anesthesiology, University of Michigan, Ann Arbor, MI 48109, USA., Preuss MH; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Refsgaard L; Laboratory for Molecular Cardiology, Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen 2100, Denmark., Bottinger EP; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Mindich Child Health Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Graham SE; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI 48109, USA., Surakka I; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI 48109, USA., Chu Y; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger 7600, Norway; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim 7491, Norway., Skogholt AH; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger 7600, Norway; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim 7491, Norway., Dalen H; Department of Cardiology, St. Olav's University Hospital, Trondheim 7030, Norway; Department of Medicine, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger 7600, Norway; Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim 7491, Norway., Boyle AP; Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA., Oral H; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI 48109, USA., Herron TJ; Department of Internal Medicine, Center for Arrhythmia Research, University of Michigan, Ann Arbor, MI 48109, USA., Kitzman J; Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Jalife J; Department of Internal Medicine, Center for Arrhythmia Research, University of Michigan, Ann Arbor, MI 48109, USA; Fundacion Centro Nacional de Investigaciones Cardiovasculares, Madrid 28029, Spain., Svendsen JH; Laboratory for Molecular Cardiology, Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen 2100, Denmark; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2200, Denmark., Olesen MS; Laboratory for Molecular Cardiology, Department of Cardiology, Rigshospitalet, University of Copenhagen, Copenhagen 2100, Denmark; Department of Biomedicine, University of Copenhagen, Copenhagen 2200, Denmark., Njølstad I; Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø 9019, Norway., Løchen ML; Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø 9019, Norway., Baras A; Regeneron Genetics Center, Tarrytown, NY 10591, USA., Gottesman O; Regeneron Genetics Center, Tarrytown, NY 10591, USA., Marcketta A; Regeneron Genetics Center, Tarrytown, NY 10591, USA., O'Dushlaine C; Regeneron Genetics Center, Tarrytown, NY 10591, USA., Ritchie MD; Geisinger Health System, Danville, PA 17822, USA., Wilsgaard T; Department of Community Medicine, Faculty of Health Sciences, UiT The Arctic University of Norway, Tromsø 9019, Norway., Loos RJF; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Frayling TM; Royal Devon & Exeter NHS Foundation Trust and University of Exeter Barrack Road Exeter, Exeter EX2 5WD, UK., Boehnke M; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim 7491, Norway., Ingelsson E; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala 75237, Sweden; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA., Carey DJ; Geisinger Health System, Danville, PA 17822, USA., Dewey FE; Regeneron Genetics Center, Tarrytown, NY 10591, USA., Kang HM; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Abecasis GR; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim 7491, Norway., Hveem K; HUNT Research Centre, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger 7600, Norway; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim 7491, Norway; Department of Medicine, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger 7600, Norway. Electronic address: kristian.hveem@ntnu.no., Willer CJ; Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan, Ann Arbor, MI 48109, USA; Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109, USA; Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA; K.G. Jebsen Center for Genetic Epidemiology, Department of Public Health, Norwegian University of Science and Technology, Trondheim 7491, Norway; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: cristen@umich.edu.
Publikováno v:
American journal of human genetics [Am J Hum Genet] 2018 Jan 04; Vol. 102 (1), pp. 103-115. Date of Electronic Publication: 2017 Dec 28.
Autor:
Gorski M; Department of Genetic Epidemiology, University Regensburg, Regensburg, Germany.; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, P.O. box 30.001, 9700 RB Groningen, The Netherlands., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Walther-Rathenau-Str. 48, 17475 Greifswald, Germany., Chu AY; NHLBI's Framingham Heart Study, Framingham, MA 01702, USA.; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02215, USA., Li M; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615N Wolfe St, Baltimore, MD, 21205, USA.; Division of Nephrology and Department of Human Genetics, University of Utah, USA., Mijatovic V; Department of Life and Reproduction Sciences, University of Verona, Strada Le Grazie 8, 37134, Verona, Italy., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, P.O. box 30.001, 9700 RB Groningen, The Netherlands., Cocca M; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132, Milano, Italy.; Department of Medical, Surgical and Health Sciences, University of Trieste, 34100, Trieste, Italy., Taliun D; Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Bolzano, Italy., Gomez F; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, MO, 63108, USA., Li Y; Division of Genetic Epidemiology, Medical Center and Faculty of Medicine - University of Freiburg, Freiburg, Germany., Tayo B; Loyola University Chicago, 2160 South First Avenue, Bldg 105, Maywood, IL 60153, USA., Tin A; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615N Wolfe St, Baltimore, MD, 21205, USA., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, MO, 63108, USA., Aspelund T; Icelandic Heart Association, Kopavogur, Iceland.; University of Iceland, Reykjavik, Iceland., Attia J; School of Medicine and Public Health, University of Newcastle, Australia.; Public Health Program, Hunter Medical Research Institute, Newcastle, New South Wales, Australia., Biffar R; Clinic for Prosthodontic Dentistry, Gerostomatology and Material Science, University Medicine Greifswald, Ferdinand-Sauerbruch-Str., 17475 Greifswald, Germany., Bochud M; Institute of Social and Preventive Medicine, Lausanne University Hospital (CHUV), Route de la Corniche 10, 1010, Lausanne, Switzerland., Boerwinkle E; University of Texas Health Science Center at Houston, USA., Borecki I; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, NY, USA., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, Ichan School of Medicine at Mount Sinai, USA., Chen MH; NHLBI's Framingham Heart Study, Framingham, MA 01702, USA., Chouraki V; Inserm U1167, Lille University, Institut Pasteur de Lille, Lille, France., Ciullo M; Institute of Genetics and Biophysics, 'Adriano Buzzati-Traverso'-CNR, Via P. Castellino 111, 80131 Napoli, Italy.; IRCCS Neuromed, via dell'Elettronica, Pozzilli (Is), Italy., Coresh J; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 615N Wolfe St, Baltimore, MD, 21205, USA., Cornelis MC; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, 680 N Lake Shore Drive, Suite 1400 Chicago, IL 60611, USA., Curhan GC; Renal Division, Brigham and Women's Hospital, USA.; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA., d'Adamo AP; Clinical Department of Medical, Surgical and Health Science, University of Trieste, Italy., Dehghan A; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands., Dengler L; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Ding J; Wake Forest School of Medicine, USA., Eiriksdottir G; Icelandic Heart Association, Kopavogur, Iceland., Endlich K; Institute of Anatomy and Cell Biology, University Medicine Greifswald, Friedrich-Loeffler-Str. 23c, 17475 Greifswald, Germany., Enroth S; Department of Immunology, Genetics, and Pathology, Biomedical Center, SciLifeLab Uppsala, Uppsala University, SE-75108 Uppsala, Sweden., Esko T; Estonian Genome Center, University of Tartu, Tartu, Estonia., Franco OH; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands., Gasparini P; Department of Medical Sciences, Chirurgical and Health Department, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health - IRCCS 'Burlo Garofolo', Trieste, Italy., Gieger C; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany., Girotto G; Department of Medical Sciences, Chirurgical and Health Department, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health - IRCCS 'Burlo Garofolo', Trieste, Italy., Gottesman O; The Charles Bronfman Institute for Personalized Medicine, Ichan School of Medicine at Mount Sinai, USA., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Gyllensten U; Department of Immunology, Genetics, and Pathology, Biomedical Center, SciLifeLab Uppsala, Uppsala University, SE-75108 Uppsala, Sweden., Hancock SJ; School of Medicine and Public Health, University of Newcastle, Australia.; Health Services Research Group, University of Newcastle, Australia., Harris TB; Intramural Research Program, Laboratory of Epidemiology and Population Studies, National Institute on Aging, USA., Helmer C; INSERM, Centre INSERM Research Center U1219, Bordeaux, France.; University Bordeaux, ISPED, Bordeaux, France., Höllerer S; Department of Genetic Epidemiology, University Regensburg, Regensburg, Germany., Hofer E; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Austria.; Institute of Medical Informatics, Statistics and Documentation, Medical University of Graz, Austria., Hofman A; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands., Holliday EG; Public Health Program, Hunter Medical Research Institute, Newcastle, New South Wales, Australia., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Friedrich-Ludwig-Jahn-Str. 15a, 17475 Greifswald, Germany., Hu FB; Department of Nutrition, Harvard School of Public Health and Channing Division of Network Medicine, Brigham and Women's Hospital, USA., Huth C; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Hutri-Kähönen N; Department of Pediatrics, Faculty of Medicine and Life Sciences, University of Tampere, Tampere 33014, Finland., Hwang SJ; NHLBI's Framingham Heart Study, Framingham, MA 01702, USA., Imboden M; Unit Chronic Disease Epidemiology, Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Switzerland., Johansson Å; Department of Immunology, Genetics, and Pathology, Biomedical Center, SciLifeLab Uppsala, Uppsala University, SE-75108 Uppsala, Sweden., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere 33521, Finland.; Department of Clinical Physiology, Faculty of Medicine and Life Sciences, University of Tampere, Tampere 33014, Finland., König W; Deutsches Herzzentrum München, Technische Universität München, Munich, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany.; Department of Internal Medicine II - Cardiology, University of Ulm Medical Center, Ulm, Germany., Kramer H; Loyola University Chicago, 2160 South First Avenue, Bldg 105, Maywood, IL 60153, USA., Krämer BK; University Medical Centre Mannheim, 5th Department of Medicine, University of Heidelberg, Theodor Kutzer Ufer 1-3, 68167 Mannheim, Germany., Kumar A; Unit Chronic Disease Epidemiology, Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Switzerland.; Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden., Kutalik Z; Institute of Social and Preventive Medicine, Lausanne University Hospital (CHUV), Route de la Corniche 10, 1010, Lausanne, Switzerland., Lambert JC; Inserm U1167, Lille University, Institut Pasteur de Lille, Lille, France., Launer LJ; Intramural Research Program, Laboratory of Epidemiology and Population Studies, National Institute on Aging, USA., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33520, Finland.; Department of Clinical Chemistry, Faculty of Medicine and Life Sciences, University of Tampere, Tampere 33014, Finland., de Borst M; University Medical Center Groningen, University of Groningen, The Netherlands., Navis G; University Medical Center Groningen, University of Groningen, The Netherlands., Swertz M; University Medical Center Groningen, University of Groningen, The Netherlands., Liu Y; Wake Forest School of Medicine, USA., Lohman K; Wake Forest School of Medicine, USA., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Ichan School of Medicine at Mount Sinai, USA.; The Mindich Child Health Development Institute, Icahn School of Medicine at Mount Sinai, USA., Lu Y; The Charles Bronfman Institute for Personalized Medicine, Ichan School of Medicine at Mount Sinai, USA., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33520, Finland.; Department of Clinical Chemistry, Faculty of Medicine and Life Sciences, University of Tampere, Tampere 33014, Finland., McEvoy MA; School of Medicine and Public Health, University of Newcastle, Australia., Meisinger C; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany., Meitinger T; Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, Technische Universität München, Munich, Germany., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia., Metzger M; Inserm U1018, University Paris-Sud, UVSQ, University Paris-Saclay, Villejuif, France., Mihailov E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Mitchell P; Centre for Vision Research, Department of Ophthalmology and Westmead Institute for Medical Research, University of Sydney C24, NSW, 2145, Australia., Nauck M; Institute of Clinical Chemistry and Laboratory Medicine-University Medicine Greifswald, Ferdinand-Sauerbruch-Str., 17475 Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Oldehinkel AJ; Department of Psychiatry, University of Groningen, University Medical Center Groningen, P.O. box 30.001, 9700 RB, Groningen, The Netherlands., Olden M; Department of Genetic Epidemiology, University Regensburg, Regensburg, Germany.; NHLBI's Framingham Heart Study, Framingham, MA 01702, USA., Wjh Penninx B; Department of Psychiatry, Vrije Universiteit, VU University Medical Center, NESDA, A.J. Ernststraat 1187, 1081HL Amsterdam, The Netherlands., Pistis G; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132, Milano, Italy., Pramstaller PP; Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Bolzano, Italy., Probst-Hensch N; Unit Chronic Disease Epidemiology, Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Switzerland., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku 20521, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku 20520, Finland., Rettig R; Institute of Physiology, University Medicine Greifswald, 17475 Greifswald, Germany., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02215, USA.; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston MA 02115, USA., Rivadeneira F; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Robino A; Institute for Maternal and Child Health - IRCCS 'Burlo Garofolo', Trieste, Italy., Rosas SE; Joslin Diabetes Center. Harvard Medical School, Boston, MA, USA., Ruderfer D; The Charles Bronfman Institute for Personalized Medicine, Ichan School of Medicine at Mount Sinai, USA., Ruggiero D; Institute of Genetics and Biophysics, 'Adriano Buzzati-Traverso'-CNR, Via P. Castellino 111, 80131 Napoli, Italy., Saba Y; Institute of Molecular Biology and Biochemistry, Centre for Molecular Medicine, Medical University of Graz, Austria., Sala C; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132, Milano, Italy., Schmidt H; Institute of Molecular Biology and Biochemistry, Centre for Molecular Medicine, Medical University of Graz, Austria., Schmidt R; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Austria., Scott RJ; School of Biomedical Sciences and Pharmacy, University of Newcastle, Australia.; Molecular Medicine, Pathology North Ph. 0409926764, Newcastle, Australia., Sedaghat S; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands., Smith AV; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Sorice R; Institute of Genetics and Biophysics, 'Adriano Buzzati-Traverso'-CNR, Via P. Castellino 111, 80131 Napoli, Italy.; IRCCS Neuromed, via dell'Elettronica, Pozzilli (Is), Italy., Stengel B; Inserm U1018, University Paris-Sud, UVSQ, University Paris-Saclay, Villejuif, France., Stracke S; Clinic for Internal Medicine A, University Medicine Greifswald, Ferdinand-Sauerbruch-Str., 17475 Greifswald, Germany., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany., Toniolo D; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, 20132, Milano, Italy., Uitterlinden AG; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Ulivi S; Institute for Maternal and Child Health - IRCCS 'Burlo Garofolo', Trieste, Italy., Viikari JS; Division of Medicine, Turku University Hospital, Turku 20521, Finland.; Department of Medicine, University of Turku, Turku 20520, Finland., Völker U; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Friedrich-Ludwig-Jahn-Str. 15a, 17475 Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Vollenweider P; Department of Internal Medicine, Lausanne University Hospital (CHUV), Lausanne, Switzerland., Völzke H; Institute for Community Medicine, University Medicine Greifswald, Walther-Rathenau-Str. 48, 17475 Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; DZD (German Center for Diabetes Research), Site Greifswald, Greifswald, Germany., Vuckovic D; Department of Medical Sciences, Chirurgical and Health Department, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health - IRCCS 'Burlo Garofolo', Trieste, Italy., Waldenberger M; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany., Jin Wang J; Centre for Vision Research, Department of Ophthalmology and Westmead Institute for Medical Research, University of Sydney C24, NSW, 2145, Australia., Yang Q; Department of Biostatistics, Boston University School of Public Health, 715 Albany Street, Boston, MA 02118, USA., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 02215, USA.; Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston MA, USA.; Broad Institute of MIT and Harvard, Cambridge MA 02142 USA., Tromp G; Weis Center for Research, Geisinger Clinic, Danville, Pennsylvania, USA., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, P.O. box 30.001, 9700 RB Groningen, The Netherlands., Heid IM; Department of Genetic Epidemiology, University Regensburg, Regensburg, Germany., Fox CS; NHLBI's Framingham Heart Study, Framingham, MA 01702, USA., Köttgen A; Division of Genetic Epidemiology, Medical Center and Faculty of Medicine - University of Freiburg, Freiburg, Germany.; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA., Pattaro C; Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Bolzano, Italy., Böger CA; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Fuchsberger C; Center for Biomedicine, European Academy of Bozen/Bolzano (EURAC), affiliated to the University of Lübeck, Bolzano, Italy.
Publikováno v:
Scientific reports [Sci Rep] 2017 Apr 28; Vol. 7, pp. 45040. Date of Electronic Publication: 2017 Apr 28.
Autor:
Wain LV; Department of Health Sciences, University of Leicester, Leicester, UK.; National Institute for Health Research, Leicester Respiratory Biomedical Research Unit, Glenfield Hospital, Leicester, UK., Shrine N; Department of Health Sciences, University of Leicester, Leicester, UK., Artigas MS; Department of Health Sciences, University of Leicester, Leicester, UK., Erzurumluoglu AM; Department of Health Sciences, University of Leicester, Leicester, UK., Noyvert B; Department of Health Sciences, University of Leicester, Leicester, UK., Bossini-Castillo L; Wellcome Trust Sanger Institute, Hinxton, UK., Obeidat M; University of British Columbia Centre for Heart Lung Innovation, St Paul's Hospital, Vancouver, British Columbia, Canada., Henry AP; Division of Respiratory Medicine, University of Nottingham, Nottingham, UK., Portelli MA; Division of Respiratory Medicine, University of Nottingham, Nottingham, UK., Hall RJ; Division of Respiratory Medicine, University of Nottingham, Nottingham, UK., Billington CK; Division of Respiratory Medicine, University of Nottingham, Nottingham, UK., Rimington TL; Division of Respiratory Medicine, University of Nottingham, Nottingham, UK., Fenech AG; Department of Clinical Pharmacology and Therapeutics, University of Malta, Msida, Malta., John C; Department of Health Sciences, University of Leicester, Leicester, UK., Blake T; Department of Health Sciences, University of Leicester, Leicester, UK., Jackson VE; Department of Health Sciences, University of Leicester, Leicester, UK., Allen RJ; Department of Health Sciences, University of Leicester, Leicester, UK., Prins BP; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK., Campbell A; Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK., Porteous DJ; Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Generation Scotland, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK., Jarvelin MR; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Faculty of Medicine, Center for Life Course Health Research, University of Oulu, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland., Wielscher M; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., James AL; Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.; Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.; School of Medicine and Pharmacology, University of Western Australia, Crawley, Western Australia, Australia., Hui J; Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia.; School of Population Health, University of Western Australia, Crawley, Western Australia, Australia.; PathWest Laboratory Medicine of Western Australia, Sir Charles Gairdner Hospital, Crawley, Western Australia, Australia.; School of Pathology and Laboratory Medicine, University of Western Australia, Crawley, Western Australia, Australia., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., Zhao JH; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., Wilson JF; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Joshi PK; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Stubbe B; Department of Internal Medicine B-Cardiology, Intensive Care, Pulmonary Medicine and Infectious Diseases, University Medicine Greifswald, Greifswald, Germany., Rawal R; Research Unit of Molecular Epidemiology, Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Schulz H; Institute of Epidemiology I, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Comprehensive Pneumology Center Munich (CPC-M), Member of the German Center for Lung Research, Neuherberg, Germany., Imboden M; Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Probst-Hensch NM; Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Karrasch S; Institute of Epidemiology I, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, Ludwig-Maximilians-Universität, Munich, Germany., Gieger C; Research Unit of Molecular Epidemiology, Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Harris SE; Medical Genetics Section, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Marten J; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Rudan I; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Enroth S; Department of Immunology, Genetics and Pathology, Uppsala Universitet, Science for Life Laboratory, Uppsala, Sweden., Gyllensten U; Department of Immunology, Genetics and Pathology, Uppsala Universitet, Science for Life Laboratory, Uppsala, Sweden., Kerr SM; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Polasek O; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; University of Split School of Medicine, Split, Croatia., Kähönen M; Department of Clinical Physiology, University of Tampere and Tampere University Hospital, Tampere, Finland., Surakka I; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; National Institute for Health and Welfare (THL), Helsinki, Finland., Vitart V; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine University of Tampere, Tampere, Finland.; Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere, Finland., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Evans DM; University of Queensland Diamantina Institute, Translational Research Institute, University of Queensland, Brisbane, Queensland, Australia.; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Henderson AJ; School of Social and Community Medicine, University of Bristol, Bristol, UK., Pennell CE; School of Women's and Infants' Health, University of Western Australia, Perth, Western Australia, Australia., Wang CA; School of Women's and Infants' Health, University of Western Australia, Perth, Western Australia, Australia., Sly PD; Child Health Research Centre, Faculty of Medicine, University of Queensland, Brisbane, Queensland, Australia., Wan ES; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Busch R; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Hobbs BD; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Litonjua AA; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Sparrow DW; VA Boston Healthcare System, Boston, Massachusetts, USA.; Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA., Gulsvik A; Department of Clinical Science, University of Bergen, Bergen, Norway., Bakke PS; Department of Clinical Science, University of Bergen, Bergen, Norway., Crapo JD; National Jewish Health, Denver, Colorado, USA.; Division of Pulmonary, Critical Care and Sleep Medicine, National Jewish Health, Denver, Colorado, USA., Beaty TH; Department of Epidemiology, Johns Hopkins University School of Public Health, Baltimore, Maryland, USA., Hansel NN; Pulmonary and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA., Mathias RA; Division of Allergy and Clinical Immunology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA., Ruczinski I; Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA., Barnes KC; Division of Biomedical Informatics and Personalized Medicine, Department of Medicine, University of Colorado School of Medicine, Anschutz Medical Campus, Aurora, Colorado, USA., Bossé Y; Department of Molecular Medicine, Laval University, Quebec City, Quebec, Canada.; Institut Universitaire de Cardiologie et de Pneumologie de Québec, Laval University, Quebec City, Quebec, Canada., Joubert P; Institut Universitaire de Cardiologie et de Pneumologie de Québec, Laval University, Quebec City, Quebec, Canada.; Department of Molecular Biology, Medical Biochemistry and Pathology, Laval University, Quebec City, Quebec, Canada., van den Berge M; University of Groningen, University Medical Center Groningen, Department of Pulmonology, GRIAC Research Institute, Groningen, the Netherlands., Brandsma CA; University of Groningen, University Medical Center Groningen, Department of Pathology and Medical Biology, GRIAC Research Institute, Groningen, the Netherlands., Paré PD; University of British Columbia Centre for Heart Lung Innovation, St Paul's Hospital, Vancouver, British Columbia, Canada.; Respiratory Division, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Sin DD; University of British Columbia Centre for Heart Lung Innovation, St Paul's Hospital, Vancouver, British Columbia, Canada.; Respiratory Division, Department of Medicine, University of British Columbia, Vancouver, British Columbia, Canada., Nickle DC; Merck Research Laboratories, Genetics and Pharmacogenomics, Boston, Massachusetts, USA., Hao K; Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Gottesman O; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, New York, USA., Dewey FE; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, New York, USA., Bruse SE; Regeneron Genetics Center, Regeneron Pharmaceuticals, Tarrytown, New York, USA., Carey DJ; Geisinger Health System, Danville, Pennsylvania, USA., Kirchner HL; Geisinger Health System, Danville, Pennsylvania, USA., Jonsson S; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Thorleifsson G; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Jonsdottir I; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland., Gislason T; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland.; Department of Respiratory Medicine and Sleep, Landspitali University Hospital Reykjavik, Reykjavik, Iceland., Stefansson K; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland., Schurmann C; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Nadkarni G; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Bottinger EP; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Loos RJ; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Mindich Child Health Development Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Walters RG; Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK., Chen Z; Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK., Millwood IY; Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK.; Medical Research Council Population Health Research Unit at the University of Oxford, Oxford, UK., Vaucher J; Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK., Kurmi OP; Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK., Li L; Chinese Academy of Medical Sciences, Beijing, China.; Department of Epidemiology and Biostatistics, Peking University Health Science Centre, Peking University, Beijing, China., Hansell AL; UK Small Area Health Statistics Unit, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, St Mary's Hospital, Paddington, London, UK., Brightling C; National Institute for Health Research, Leicester Respiratory Biomedical Research Unit, Glenfield Hospital, Leicester, UK.; Department of Infection, Inflammation and Immunity, Institute for Lung Health, University of Leicester, Leicester, UK., Zeggini E; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton, UK., Cho MH; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Silverman EK; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.; Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Sayers I; Division of Respiratory Medicine, University of Nottingham, Nottingham, UK., Trynka G; Wellcome Trust Sanger Institute, Hinxton, UK., Morris AP; Department of Biostatistics, University of Liverpool, Liverpool, UK., Strachan DP; Population Health Research Institute, St George's, University of London, London, UK., Hall IP; Division of Respiratory Medicine, University of Nottingham, Nottingham, UK., Tobin MD; Department of Health Sciences, University of Leicester, Leicester, UK.; National Institute for Health Research, Leicester Respiratory Biomedical Research Unit, Glenfield Hospital, Leicester, UK.
Publikováno v:
Nature genetics [Nat Genet] 2017 Mar; Vol. 49 (3), pp. 416-425. Date of Electronic Publication: 2017 Feb 06.
Autor:
Jones GT; For the author affiliations, please see the Appendix. m.bown@le.ac.uk greg.jones@otago.ac.nz., Tromp G; For the author affiliations, please see the Appendix., Kuivaniemi H; For the author affiliations, please see the Appendix., Gretarsdottir S; For the author affiliations, please see the Appendix., Baas AF; For the author affiliations, please see the Appendix., Giusti B; For the author affiliations, please see the Appendix., Strauss E; For the author affiliations, please see the Appendix., Van't Hof FN; For the author affiliations, please see the Appendix., Webb TR; For the author affiliations, please see the Appendix., Erdman R; For the author affiliations, please see the Appendix., Ritchie MD; For the author affiliations, please see the Appendix., Elmore JR; For the author affiliations, please see the Appendix., Verma A; For the author affiliations, please see the Appendix., Pendergrass S; For the author affiliations, please see the Appendix., Kullo IJ; For the author affiliations, please see the Appendix., Ye Z; For the author affiliations, please see the Appendix., Peissig PL; For the author affiliations, please see the Appendix., Gottesman O; For the author affiliations, please see the Appendix., Verma SS; For the author affiliations, please see the Appendix., Malinowski J; For the author affiliations, please see the Appendix., Rasmussen-Torvik LJ; For the author affiliations, please see the Appendix., Borthwick KM; For the author affiliations, please see the Appendix., Smelser DT; For the author affiliations, please see the Appendix., Crosslin DR; For the author affiliations, please see the Appendix., de Andrade M; For the author affiliations, please see the Appendix., Ryer EJ; For the author affiliations, please see the Appendix., McCarty CA; For the author affiliations, please see the Appendix., Böttinger EP; For the author affiliations, please see the Appendix., Pacheco JA; For the author affiliations, please see the Appendix., Crawford DC; For the author affiliations, please see the Appendix., Carrell DS; For the author affiliations, please see the Appendix., Gerhard GS; For the author affiliations, please see the Appendix., Franklin DP; For the author affiliations, please see the Appendix., Carey DJ; For the author affiliations, please see the Appendix., Phillips VL; For the author affiliations, please see the Appendix., Williams MJ; For the author affiliations, please see the Appendix., Wei W; For the author affiliations, please see the Appendix., Blair R; For the author affiliations, please see the Appendix., Hill AA; For the author affiliations, please see the Appendix., Vasudevan TM; For the author affiliations, please see the Appendix., Lewis DR; For the author affiliations, please see the Appendix., Thomson IA; For the author affiliations, please see the Appendix., Krysa J; For the author affiliations, please see the Appendix., Hill GB; For the author affiliations, please see the Appendix., Roake J; For the author affiliations, please see the Appendix., Merriman TR; For the author affiliations, please see the Appendix., Oszkinis G; For the author affiliations, please see the Appendix., Galora S; For the author affiliations, please see the Appendix., Saracini C; For the author affiliations, please see the Appendix., Abbate R; For the author affiliations, please see the Appendix., Pulli R; For the author affiliations, please see the Appendix., Pratesi C; For the author affiliations, please see the Appendix., Saratzis A; For the author affiliations, please see the Appendix., Verissimo AR; For the author affiliations, please see the Appendix., Bumpstead S; For the author affiliations, please see the Appendix., Badger SA; For the author affiliations, please see the Appendix., Clough RE; For the author affiliations, please see the Appendix., Cockerill G; For the author affiliations, please see the Appendix., Hafez H; For the author affiliations, please see the Appendix., Scott DJ; For the author affiliations, please see the Appendix., Futers TS; For the author affiliations, please see the Appendix., Romaine SP; For the author affiliations, please see the Appendix., Bridge K; For the author affiliations, please see the Appendix., Griffin KJ; For the author affiliations, please see the Appendix., Bailey MA; For the author affiliations, please see the Appendix., Smith A; For the author affiliations, please see the Appendix., Thompson MM; For the author affiliations, please see the Appendix., van Bockxmeer FM; For the author affiliations, please see the Appendix., Matthiasson SE; For the author affiliations, please see the Appendix., Thorleifsson G; For the author affiliations, please see the Appendix., Thorsteinsdottir U; For the author affiliations, please see the Appendix., Blankensteijn JD; For the author affiliations, please see the Appendix., Teijink JA; For the author affiliations, please see the Appendix., Wijmenga C; For the author affiliations, please see the Appendix., de Graaf J; For the author affiliations, please see the Appendix., Kiemeney LA; For the author affiliations, please see the Appendix., Lindholt JS; For the author affiliations, please see the Appendix., Hughes A; For the author affiliations, please see the Appendix., Bradley DT; For the author affiliations, please see the Appendix., Stirrups K; For the author affiliations, please see the Appendix., Golledge J; For the author affiliations, please see the Appendix., Norman PE; For the author affiliations, please see the Appendix., Powell JT; For the author affiliations, please see the Appendix., Humphries SE; For the author affiliations, please see the Appendix., Hamby SE; For the author affiliations, please see the Appendix., Goodall AH; For the author affiliations, please see the Appendix., Nelson CP; For the author affiliations, please see the Appendix., Sakalihasan N; For the author affiliations, please see the Appendix., Courtois A; For the author affiliations, please see the Appendix., Ferrell RE; For the author affiliations, please see the Appendix., Eriksson P; For the author affiliations, please see the Appendix., Folkersen L; For the author affiliations, please see the Appendix., Franco-Cereceda A; For the author affiliations, please see the Appendix., Eicher JD; For the author affiliations, please see the Appendix., Johnson AD; For the author affiliations, please see the Appendix., Betsholtz C; For the author affiliations, please see the Appendix., Ruusalepp A; For the author affiliations, please see the Appendix., Franzén O; For the author affiliations, please see the Appendix., Schadt EE; For the author affiliations, please see the Appendix., Björkegren JL; For the author affiliations, please see the Appendix., Lipovich L; For the author affiliations, please see the Appendix., Drolet AM; For the author affiliations, please see the Appendix., Verhoeven EL; For the author affiliations, please see the Appendix., Zeebregts CJ; For the author affiliations, please see the Appendix., Geelkerken RH; For the author affiliations, please see the Appendix., van Sambeek MR; For the author affiliations, please see the Appendix., van Sterkenburg SM; For the author affiliations, please see the Appendix., de Vries JP; For the author affiliations, please see the Appendix., Stefansson K; For the author affiliations, please see the Appendix., Thompson JR; For the author affiliations, please see the Appendix., de Bakker PI; For the author affiliations, please see the Appendix., Deloukas P; For the author affiliations, please see the Appendix., Sayers RD; For the author affiliations, please see the Appendix., Harrison SC; For the author affiliations, please see the Appendix., van Rij AM; For the author affiliations, please see the Appendix., Samani NJ; For the author affiliations, please see the Appendix., Bown MJ; For the author affiliations, please see the Appendix. m.bown@le.ac.uk greg.jones@otago.ac.nz.
Publikováno v:
Circulation research [Circ Res] 2017 Jan 20; Vol. 120 (2), pp. 341-353. Date of Electronic Publication: 2016 Nov 29.
Autor:
Gaulton KJ; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Genetics, Stanford University, Stanford, California, USA., Ferreira T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Lee Y; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Raimondo A; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Mägi R; Estonian Genome Center, University of Tartu, Tartu, Estonia., Reschen ME; Centre for Cellular and Molecular Physiology, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Locke A; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Rayner NW; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK.; Wellcome Trust Sanger Institute, Hinxton, UK., Robertson N; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Scott RA; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., Prokopenko I; Genomics of Common Disease, Imperial College London, London, UK., Scott LJ; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Green T; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Sparso T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Thuillier D; Lille Institute of Biology, European Genomics Institute of Diabetes, Lille, France., Yengo L; Lille Institute of Biology, European Genomics Institute of Diabetes, Lille, France., Grallert H; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Wahl S; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Frånberg M; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.; Science for Life Laboratory, Stockholm, Sweden.; Department for Numerical Analysis and Computer Science, Stockholm University, Stockholm, Sweden., Strawbridge RJ; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Kestler H; Leibniz Institute for Age Research, Fritz Lipmann Institute, Jena, Germany.; Medical Systems Biology, Ulm University, Ulm, Germany., Chheda H; Finnish Institute for Molecular Medicine (FIMM), Helsinki, Finland., Eisele L; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, Essen, Germany., Gustafsson S; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Steinthorsdottir V; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Thorleifsson G; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Qi L; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, Louisiana, USA., Karssen LC; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., van Leeuwen EM; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Willems SM; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK.; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Li M; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA., Chen H; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.; Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, USA., Fuchsberger C; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Kwan P; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Ma C; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Linderman M; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Lu Y; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Thomsen SK; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Rundle JK; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Beer NL; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., van de Bunt M; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Chalisey A; Centre for Cellular and Molecular Physiology, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Kang HM; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Voight BF; Department of Pharmacology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Abecasis GR; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Almgren P; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden., Baldassarre D; Centro Cardiologico Monzino, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Milan, Italy.; Dipartimento di Scienze Farmacologiche e Biomolecolari, Università di Milano, Milan, Italy., Balkau B; INSERM Centre de Recherche Epidémiologie et Santé des Populations (CESP) U1018, Villejuif, France.; University Paris Sud 11, UMRS 1018, Villejuif, France., Benediktsson R; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Landspitali University Hospital, Reykjavik, Iceland., Blüher M; Integrated Treatment and Research (IFB) Center for Adiposity Diseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Boeing H; German Institute of Human Nutrition, Potsdam-Rehbruecke, Germany., Bonnycastle LL; National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA., Bottinger EP; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Burtt NP; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Carey J; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Charpentier G; Endocrinology-Diabetology Unit, Corbeil-Essonnes Hospital, Corbeil-Essonnes, France., Chines PS; National Human Genome Research Institute, US National Institutes of Health, Bethesda, Maryland, USA., Cornelis MC; Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA., Couper DJ; Collaborative Studies Coordinating Center, Department of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA., Crenshaw AT; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., van Dam RM; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA.; Saw Swee Hock School of Public Health, National University of Singapore, Singapore., Doney AS; Diabetes Research Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee, UK.; Pharmacogenomics Centre, Biomedical Research Institute, University of Dundee, Ninewells Hospital, Dundee, UK., Dorkhan M; Lund University Diabetes Centre, Department of Clinical Science Malmo, Novo Nordisk Scandinavia, Malmo, Sweden., Edkins S; Wellcome Trust Sanger Institute, Hinxton, UK., Eriksson JG; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.; Department of General Practice and Primary Health Care, University of Helsinki, Helsinki, Finland.; Unit of General Practice, Helsinki University General Hospital, Helsinki, Finland.; Folkhalsan Research Center, Helsinki, Finland., Esko T; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Division of Endocrinology, Children's Hospital, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Eury E; CNRS UMR 8199, Institute of Biology and Lille 2 University, Pasteur Institute, Lille, France., Fadista J; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden., Flannick J; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Fontanillas P; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Fox C; National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts, USA.; Division of Endocrinology and Metabolism, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Franks PW; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA.; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden.; Department of Clinical Sciences, Lund University, Malmo, Sweden.; Department of Public Health and Clinical Medicine, Umea University, Umea, Sweden., Gertow K; Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Gigante B; Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Gottesman O; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Grant GB; Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Groves CJ; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK., Hassinen M; Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Have CT; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Herder C; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Center for Diabetes Research at Heinrich Heine University Dusseldorf, Dusseldorf, Germany.; German Center for Diabetes Research, partner site Dusseldorf, Dusseldorf, Germany., Holmen OL; Nord-Trøndelag Health Study (HUNT) Research Center, Department of Public Health and General Practice, Norwegian University of Science and Technology, Levanger, Norway., Hreidarsson AB; Landspitali University Hospital, Reykjavik, Iceland., Humphries SE; Cardiovascular Genetics, British Heart Foundation (BHF) Laboratories, Institute of Cardiovascular Sciences, University College London, London, UK., Hunter DJ; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA.; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Program in Genetic Epidemiology and Statistical Genetics, Harvard School of Public Health, Boston, Massachusetts, USA., Jackson AU; Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, USA., Jonsson A; Lund University Diabetes Centre, Department of Clinical Science Malmo, Scania University Hospital, Lund University, Malmo, Sweden., Jørgensen ME; Steno Diabetes Center, Gentofte, Denmark., Jørgensen T; Research Centre for Prevention and Health, Capital Region of Denmark, Copenhagen, Denmark.; Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Faculty of Medicine, University of Aalborg, Aalborg, Denmark., Kao WH; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA., Kerrison ND; Medical Research Council (MRC) Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK., Kinnunen L; 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Publikováno v:
Nature genetics [Nat Genet] 2015 Dec; Vol. 47 (12), pp. 1415-25. Date of Electronic Publication: 2015 Nov 09.
Autor:
Wain, LV, Shrine, N, Artigas, MS, Erzurumluoglu, AM, Noyvert, B, Bossini-Castillo, L, Obeidat, M, Henry, AP, Portelli, MA, Hall, RJ, Billington, CK, Rimington, TL, Fenech, AG, John, C, Blake, T, Jackson, VE, Allen, RJ, Prins, BP, Understanding Society Scientific Group, Campbell, A, Porteous, DJ, Jarvelin, M-R, Wielscher, M, James, AL, Hui, J, Wareham, NJ, Zhao, JH, Wilson, JF, Joshi, PK, Stubbe, B, Rawal, R, Schulz, H, Imboden, M, Probst-Hensch, NM, Karrasch, S, Gieger, C, Deary, IJ, Harris, SE, Marten, J, Rudan, I, Enroth, S, Gyllensten, U, Kerr, SM, Polasek, O, Kähönen, M, Surakka, I, Vitart, V, Hayward, C, Lehtimäki, T, Raitakari, OT, Evans, DM, Henderson, AJ, Pennell, CE, Wang, CA, Sly, PD, Wan, ES, Busch, R, Hobbs, BD, Litonjua, AA, Sparrow, DW, Gulsvik, A, Bakke, PS, Crapo, JD, Beaty, TH, Hansel, NN, Mathias, RA, Ruczinski, I, Barnes, KC, Bossé, Y, Joubert, P, Van Den Berge, M, Brandsma, C-A, Paré, PD, Sin, DD, Nickle, DC, Hao, K, Gottesman, O, Dewey, FE, Bruse, SE, Carey, DJ, Kirchner, HL, Geisinger-Regeneron DiscovEHR Collaboration, Jonsson, S, Thorleifsson, G, Jonsdottir, I, Gislason, T, Stefansson, K, Schurmann, C, Nadkarni, G, Bottinger, EP, Loos, RJF, Walters, RG, Chen, Z, Millwood, IY, Vaucher, J, Kurmi, OP, Li, L, Hansell, AL, Brightling, C, Zeggini, E, Cho, MH, Silverman, EK, Sayers, I, Trynka, G, Morris, AP, Strachan, DP, Hall, IP, Tobin, MD
Chronic obstructive pulmonary disease (COPD) is characterized by reduced lung function and is the third leading cause of death globally. Through genome-wide association discovery in 48,943 individuals, selected from extremes of the lung function dist
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