Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Fornage, M"'
Autor:
Patel K; McWilliams School of Biomedical Informatics, University of Texas Health Science Center, Houston, TX, 77030, USA., Xie Z; McWilliams School of Biomedical Informatics, University of Texas Health Science Center, Houston, TX, 77030, USA., Yuan H; Department of Computer Science and Engineering, Texas A&M University, College Station, TX, 77843, USA., Islam SMS; McWilliams School of Biomedical Informatics, University of Texas Health Science Center, Houston, TX, 77030, USA., Xie Y; Department of Computer Science and Engineering, Texas A&M University, College Station, TX, 77843, USA., He W; McWilliams School of Biomedical Informatics, University of Texas Health Science Center, Houston, TX, 77030, USA., Zhang W; School of Public Health, University of Texas Health Science Center, Houston, TX, 77030, USA., Gottlieb A; McWilliams School of Biomedical Informatics, University of Texas Health Science Center, Houston, TX, 77030, USA., Chen H; McWilliams School of Biomedical Informatics, University of Texas Health Science Center, Houston, TX, 77030, USA.; School of Public Health, University of Texas Health Science Center, Houston, TX, 77030, USA., Giancardo L; McWilliams School of Biomedical Informatics, University of Texas Health Science Center, Houston, TX, 77030, USA., Knaack A; Department of Neurology and Imaging of Dementia and Aging (IDeA) Laboratory, University of California at Davis, Davis, CA, 95618, USA., Fletcher E; Department of Neurology and Imaging of Dementia and Aging (IDeA) Laboratory, University of California at Davis, Davis, CA, 95618, USA., Fornage M; School of Public Health, University of Texas Health Science Center, Houston, TX, 77030, USA.; McGovern Medical School, University of Texas Health Science Center, Houston, TX, 77030, USA., Ji S; Department of Computer Science and Engineering, Texas A&M University, College Station, TX, 77843, USA., Zhi D; McWilliams School of Biomedical Informatics, University of Texas Health Science Center, Houston, TX, 77030, USA. Degui.Zhi@uth.tmc.edu.
Publikováno v:
Communications biology [Commun Biol] 2024 Apr 05; Vol. 7 (1), pp. 414. Date of Electronic Publication: 2024 Apr 05.
Autor:
Hu Y; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA (Y.H., J.W.H., A.P.R., C.K.)., Haessler JW; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA (Y.H., J.W.H., A.P.R., C.K.)., Manansala R; School of Public Health, University of Wisconsin-Milwaukee (R.M., P.L.A.)., Wiggins KL; Cardiovascular Health Research Unit, Department of Medicine (K.L.W., J.C.B., B.M.P.)., Moscati A; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, NY (A.M., R.D., R.J.F.L.)., Beiser A; Department of Neurology (A.B., N.L.H.-C., S.S.), Boston University School of Medicine, MA.; Department of Biostatistics (A.B., C.S.), Boston University School of Public Health, MA., Heard-Costa NL; Department of Neurology (A.B., N.L.H.-C., S.S.), Boston University School of Medicine, MA., Sarnowski C; Department of Biostatistics (A.B., C.S.), Boston University School of Public Health, MA., Raffield LM; Department of Genetics, University of North Carolina, Chapel Hill (L.M.R)., Chung J; Department of Medicine (J.C., R.S.V.), Boston University School of Medicine, MA.; Center for Genomic Medicine (J.C., S.M., C.D.A., J.R.), Massachusetts General Hospital, Boston., Marini S; Center for Genomic Medicine (J.C., S.M., C.D.A., J.R.), Massachusetts General Hospital, Boston.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA (S.M., C.D.A., J.R.)., Anderson CD; Center for Genomic Medicine (J.C., S.M., C.D.A., J.R.), Massachusetts General Hospital, Boston.; Henry and Allison McCance Center for Brain Health (C.D.A., J.R.), Massachusetts General Hospital, Boston.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA (S.M., C.D.A., J.R.)., Rosand J; Center for Genomic Medicine (J.C., S.M., C.D.A., J.R.), Massachusetts General Hospital, Boston.; Henry and Allison McCance Center for Brain Health (C.D.A., J.R.), Massachusetts General Hospital, Boston.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA (S.M., C.D.A., J.R.)., Xu H; Department of Medicine, University of Maryland School of Medicine, Baltimore (H.X., B.D.M.)., Sun X; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA (X.S., T.N.K.)., Kelly TN; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA (X.S., T.N.K.)., Wong Q; Department of Biostatistics (Q.W.), University of Washington, Seattle., Lange LA; Department of Medicine, University of Colorado, Denver, CO (L.A.L.)., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA (J.I.R.)., Correa A; Department of Pediatrics and Medicine, University of Mississippi Medical Center, Jackson, MS (A.C.)., Vasan RS; Department of Medicine (J.C., R.S.V.), Boston University School of Medicine, MA., Seshadri S; Department of Neurology (A.B., N.L.H.-C., S.S.), Boston University School of Medicine, MA.; Glenn Biggs Institute for Alzheimer's & Neurodegenerative Diseases, University of Texas Health Sciences Center, San Antonio (S.S.)., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville (S.S.R.)., Do R; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, NY (A.M., R.D., R.J.F.L.).; Department of Genetics and Genomic Sciences (R.D.), The Icahn School of Medicine at Mount Sinai, NY., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, NY (A.M., R.D., R.J.F.L.).; The Mindich Child Health and Development Institute (R.J.F.L.), The Icahn School of Medicine at Mount Sinai, NY., Longstreth WT Jr; Department of Neurology (W.T.L., D.L.T.), University of Washington, Seattle.; Department of Epidemiology (W.T.L., B.M.P., A.P.R.), University of Washington, Seattle., Bis JC; Cardiovascular Health Research Unit, Department of Medicine (K.L.W., J.C.B., B.M.P.)., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine (K.L.W., J.C.B., B.M.P.).; Department of Epidemiology (W.T.L., B.M.P., A.P.R.), University of Washington, Seattle.; Department of Health Services (B.M.P.), University of Washington, Seattle., Tirschwell DL; Department of Neurology (W.T.L., D.L.T.), University of Washington, Seattle., Assimes TL; Department of Medicine, Stanford University, CA (T.L.A.)., Silver B; Department of Neurology, University of Massachusetts Medical School, Worcester (B.S.)., Liu S; Center for Global Cardiometabolic Health, Departments of Epidemiology, Medicine, and Surgery, Brown University, Providence, RI (S.L.)., Jackson R; Division of Endocrinology Diabetes and Metabolism, The Ohio State University, Columbus (R.J.)., Wassertheil-Smoller S; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, NY (S.W.-S.)., Mitchell BD; Department of Medicine, University of Maryland School of Medicine, Baltimore (H.X., B.D.M.).; Geriatrics Research and Education Clinical Center, Baltimore Veterans Administration Medical Center, Baltimore, MD (B.D.M.)., Fornage M; Institute of Molecular Medicine, University of Texas Health Science Center at Houston (M.F.)., Auer PL; School of Public Health, University of Wisconsin-Milwaukee (R.M., P.L.A.)., Reiner AP; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA (Y.H., J.W.H., A.P.R., C.K.).; Department of Epidemiology (W.T.L., B.M.P., A.P.R.), University of Washington, Seattle., Kooperberg C; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA (Y.H., J.W.H., A.P.R., C.K.).
Publikováno v:
Stroke [Stroke] 2022 Mar; Vol. 53 (3), pp. 875-885. Date of Electronic Publication: 2021 Nov 03.
Autor:
McCartney DL; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh, EH4 2XU, UK., Min JL; MRC Integrative Epidemiology Unit University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Richmond RC; MRC Integrative Epidemiology Unit University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Lu AT; Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA., Sobczyk MK; MRC Integrative Epidemiology Unit University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Davies G; Lothian Birth Cohorts, Department of Psychology, University of Edinburgh, Edinburgh, EH8 9JZ, UK., Broer L; Department of Internal Medicine, Erasmus MC, Rotterdam, the Netherlands., Guo X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Jeong A; Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Jung J; National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, USA., Kasela S; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Katrinli S; Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA, USA., Kuo PL; Longitudinal Study Section, Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA., Matias-Garcia PR; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764, Neuherberg, Bavaria, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764, Neuherberg, Bavaria, Germany.; TUM School of Medicine, Technical University of Munich, Munich, Germany., Mishra PP; Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, 33520, Tampere, Finland., Nygaard M; Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, Odense, Denmark.; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark., Palviainen T; Institute for Molecular Medicine Finland, FIMM, HiLIFE, University of Helsinki, Helsinki, Finland., Patki A; Department of Biostatistics, University of Alabama at Birmingham, Birmingham, USA., Raffield LM; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Ratliff SM; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, USA., Richardson TG; MRC Integrative Epidemiology Unit University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Robinson O; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Soerensen M; Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, Odense, Denmark.; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark.; Department of Clinical Biochemistry and Pharmacology, Odense University Hospital, Odense, Denmark., Sun D; Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China., Tsai PC; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.; Department of Biomedical Sciences, Chang Gung University, Taoyuan, Taiwan.; Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Memorial Hospital, Taoyuan City, Taiwan., van der Zee MD; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands., Walker RM; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh, EH4 2XU, UK., Wang X; Cancer Epidemiology Division, Cancer Council Victoria, 615 St Kilda Road, Melbourne, Victoria, 3004, Australia., Wang Y; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden., Xia R; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Xu Z; National Institute of Environmental Health Sciences, Research Triangle Park, NC, 27709, USA., Yao J; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, USA., Correa A; Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Boerwinkle E; School of Public Health, University of Texas Health Science Center at Houston, Houston, TX, USA., Dugué PA; Cancer Epidemiology Division, Cancer Council Victoria, 615 St Kilda Road, Melbourne, Victoria, 3004, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, 3168, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, 207 Bouverie Street, Melbourne, Victoria, 3010, Australia., Durda P; Department of Pathology & Laboratory Medicine, Larner College of Medicine, University of Vermont, Burlington, VT, 05446, USA., Elliott HR; MRC Integrative Epidemiology Unit University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Gieger C; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764, Neuherberg, Bavaria, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764, Neuherberg, Bavaria, Germany., de Geus EJC; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands., Harris SE; Lothian Birth Cohorts, Department of Psychology, University of Edinburgh, Edinburgh, EH8 9JZ, UK., Hemani G; MRC Integrative Epidemiology Unit University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Imboden M; Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, and Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, 33521, Tampere, Finland., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, USA., Kresovich JK; National Institute of Environmental Health Sciences, Research Triangle Park, NC, 27709, USA., Li S; Children's Minnesota Research Institute, Children's Minnesota, Minneapolis, MN, 55404, USA., Lunetta KL; Department of Biostatistics, Boston University School of Public Health, Boston, USA., Mangino M; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.; NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust, London, SE1 9RT, UK., Mason D; Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK., McIntosh AM; Division of Psychiatry, University of Edinburgh, Edinburgh, UK., Mengel-From J; Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, Odense, Denmark.; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark., Moore AZ; Longitudinal Study Section, Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA., Murabito JM; Section of General Internal Medicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA., Ollikainen M; Institute for Molecular Medicine Finland, FIMM, HiLIFE, University of Helsinki, Helsinki, Finland., Pankow JS; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden., Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764, Neuherberg, Bavaria, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Polidoro S; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Porteous DJ; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh, EH4 2XU, UK., Raitakari O; Centre for Population Health Research, University of Turku and Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland., Rich SS; Department of Public Health Sciences, Center for Public Health Genomics, University of Virginia, Charlottesville, VA, 22908, USA., Sandler DP; National Institute of Environmental Health Sciences, Research Triangle Park, NC, 27709, USA., Sillanpää E; Institute for Molecular Medicine Finland, FIMM, HiLIFE, University of Helsinki, Helsinki, Finland.; Gerontology Research Center, Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland., Smith AK; Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, GA, USA.; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA., Southey MC; Cancer Epidemiology Division, Cancer Council Victoria, 615 St Kilda Road, Melbourne, Victoria, 3004, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, 3168, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, 207 Bouverie Street, Melbourne, Victoria, 3010, Australia., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764, Neuherberg, Bavaria, Germany.; Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center, Johannes Gutenberg University, 55101, Mainz, Germany.; Chair of Genetic Epidemiology, Institute for Medical Information Processing, Biometry, and Epidemiology, Faculty of Medicine, Ludwig-Maximilians-Universität München, Munich, Germany., Tiwari H; Department of Biostatistics, University of Alabama at Birmingham, Birmingham, USA., Tanaka T; Longitudinal Study Section, Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA., Tillin T; MRC Unit for Lifelong Health and Ageing at UCL, London, UK., Uitterlinden AG; Department of Internal Medicine, Erasmus MC, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands., Van Den Berg DJ; Center for Genetic Epidemiology, Department of Preventive Medicine, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA, USA., van Dongen J; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands., Wilson JG; Division of Cardiology, Beth Israel Deaconess Medical Center, Boston, MA, USA.; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA., Wright J; Bradford Institute for Health Research, Bradford Teaching Hospitals NHS Foundation Trust, Bradford, UK., Yet I; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK.; Department of Bioinformatics, Institute of Health Sciences, Hacettepe University, 06100, Ankara, Turkey., Arnett D; Deans Office, College of Public Health, University of Kentucky, Lexington, UK., Bandinelli S; Geriatric Unit, Azienda Sanitaria Toscana Centro, Florence, Italy., Bell JT; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Binder AM; Department of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, CA, USA.; Population Sciences in the Pacific Program (Cancer Epidemiology), University of Hawai'i Cancer Center, University of Hawai'i, Honolulu, HI, USA., Boomsma DI; Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.; Amsterdam Public Health Research Institute, Amsterdam, The Netherlands., Chen W; Department of Epidemiology, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA, 70112, USA., Christensen K; Epidemiology, Biostatistics and Biodemography, Department of Public Health, University of Southern Denmark, Odense, Denmark.; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark.; Department of Clinical Biochemistry and Pharmacology, Odense University Hospital, Odense, Denmark., Conneely KN; Department of Human Genetics, Emory University School of Medicine, Atlanta, GA, USA., Elliott P; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Ferrucci L; Longitudinal Study Section, Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA., Fornage M; Brown Foundation Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, TX, USA., Hägg S; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Solna, Sweden., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Cancer, University of Edinburgh, Crewe Rd. South, Edinburgh, EH4 2XU, UK., Irvin M; Dept of Epidemiology, University of Alabama at Birmingham, Birmingham, USA., Kaprio J; Institute for Molecular Medicine Finland, FIMM, HiLIFE, University of Helsinki, Helsinki, Finland.; Department of Public Health, University of Helsinki, Helsinki, Finland., Lawlor DA; MRC Integrative Epidemiology Unit University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.; Bristol NIHR Biomedical Research Centre, Bristol, UK., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, 33520, Tampere, Finland., Lohoff FW; National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, USA., Milani L; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Milne RL; Cancer Epidemiology Division, Cancer Council Victoria, 615 St Kilda Road, Melbourne, Victoria, 3004, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, Victoria, 3168, Australia.; Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, 207 Bouverie Street, Melbourne, Victoria, 3010, Australia., Probst-Hensch N; Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Basel, Switzerland., Reiner AP; Department of Epidemiology, University of Washington, Seattle, WA, USA., Ritz B; Department of Epidemiology, Fielding School of Public Health, University of California, Los Angeles, CA, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, USA., Taylor JA; National Institute of Environmental Health Sciences, Research Triangle Park, NC, 27709, USA., van Meurs JBJ; Department of Internal Medicine, Erasmus MC, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus MC, Rotterdam, the Netherlands., Vineis P; MRC Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Waldenberger M; Research Unit Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764, Neuherberg, Bavaria, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, 85764, Neuherberg, Bavaria, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany., Deary IJ; Lothian Birth Cohorts, Department of Psychology, University of Edinburgh, Edinburgh, EH8 9JZ, UK., Relton CL; MRC Integrative Epidemiology Unit University of Bristol, Bristol, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK., Horvath S; Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA. shorvath@mednet.ucla.edu.; Department of Biostatistics, Fielding School of Public Health, University of California Los Angeles, Los Angeles, CA, 90095, USA. shorvath@mednet.ucla.edu., Marioni RE; Centre for Genomic and Experimental Medicine, Institute of Genetics and Cancer, University of Edinburgh, Crewe Road South, Edinburgh, EH4 2XU, UK. riccardo.marioni@ed.ac.uk.
Publikováno v:
Genome biology [Genome Biol] 2021 Jun 29; Vol. 22 (1), pp. 194. Date of Electronic Publication: 2021 Jun 29.
Autor:
Noordam R; Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands. r.noordam@lumc.nl., Bos MM; Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands., Wang H; Division of Sleep and Circadian Disorders, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA., Winkler TW; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Bentley AR; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Kilpeläinen TO; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200, Denmark.; Department of Environmental Medicine and Public Health, The Icahn School of Medicine at Mount Sinai, New York, New York, USA., de Vries PS; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Sung YJ; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA., Schwander K; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA., Cade BE; Division of Sleep and Circadian Disorders, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA., Manning A; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Aschard H; Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA.; Centre de Bioinformatique, Biostatistique et Biologie Intégrative (C3BI), Institut Pasteur, Paris, France., Brown MR; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Chen H; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Center for Precision Health, School of Public Health & School of Biomedical Informatics, The University of Texas Health Science Center at Houston, Houston, TX, USA., Franceschini N; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Musani SK; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Richard M; Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Vojinovic D; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Aslibekyan S; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA., Bartz TM; Cardiovascular Health Research Unit, Biostatistics and Medicine, University of Washington, Seattle, WA, USA., de Las Fuentes L; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA.; Cardiovascular Division, Department of Medicine, Washington University School of Medicine, St. Louis, MO, USA., Feitosa M; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Horimoto AR; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo, SP, Brazil., Ilkov M; Icelandic Heart Association, Kopavogur, Iceland., Kho M; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Kraja A; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Li C; Epidemiology and Biostatistics, University of Georgia at Athens College of Public Health, Athens, GA, USA., Lim E; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Liu Y; Public Health Sciences, Epidemiology and Prevention, Wake Forest University Health Sciences, Winston-Salem, NC, USA., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, Netherlands., Rankinen T; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA, USA., Tajuddin SM; Health Disparities Research Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., van der Spek A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Wang Z; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Marten J; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Laville V; Centre de Bioinformatique, Biostatistique et Biologie Intégrative (C3BI), Institut Pasteur, Paris, France., Alver M; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.; Department of Biotechnology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia., Evangelou E; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Graff ME; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., He M; Department of Occupational and Environmental Health and State Key Laboratory of Environmental Health for Incubating, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Kühnel B; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Marques-Vidal P; Medicine, Internal Medicine, Lausanne University Hospital, Lausanne, Switzerland., Nolte IM; University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands., Palmer ND; Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Rauramaa R; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA., Snieder H; University of Groningen, University Medical Center Groningen, Department of Epidemiology, Groningen, The Netherlands., Weiss S; Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Wen W; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA., Yanek LR; Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Adolfo C; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Ballantyne C; Section of Cardiovascular Research, Baylor College of Medicine, Houston, TX, USA.; Houston Methodist Debakey Heart and Vascular Center, Houston, TX, USA., Bielak L; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Biermasz NR; Department of Internal Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Leiden, The Netherlands., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Dimou N; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Eiriksdottir G; Icelandic Heart Association, Kopavogur, Iceland., Gao C; Molecular Genetics and Genomics Program, Wake Forest School of Medicine, Winston-Salem, NC, USA., Gharib SA; Computational Medicine Core, Center for Lung Biology, UW Medicine Sleep Center, Medicine, University of Washington, Seattle, WA, USA., Gottlieb DJ; Division of Sleep and Circadian Disorders, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; VA Boston Healthcare System, Boston, MA, USA., Haba-Rubio J; Medicine, Sleep Laboratory, Lausanne University Hospital, Lausanne, Switzerland., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA., Heikkinen S; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Finland., Heinzer R; Medicine, Sleep Laboratory, Lausanne University Hospital, Lausanne, Switzerland., Hixson JE; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, Department of Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Ikram MA; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands., Komulainen P; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland., Krieger JE; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo, SP, Brazil., Lee J; Division of Sleep and Circadian Disorders, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA., Liu J; Fred Hutchinson Cancer Research Center, University of Washington School of Public Health, Seattle, WA, USA., Lohman KK; Public Health Sciences, Biostatistical Sciences, Wake Forest University Health Sciences, Winston-Salem, NC, USA., Luik AI; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Mägi R; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Martin LW; Cardiology, School of Medicine and Health Sciences, George Washington University, Washington, D.C., USA., Meitinger T; Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Metspalu A; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.; Department of Biotechnology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia., Milaneschi Y; Cardiology, School of Medicine and Health Sciences, George Washington University, Washington, D.C., USA., Nalls MA; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD, USA.; Data Tecnica International, Glen Echo, MD, USA., O'Connell J; Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD, USA.; Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Neuherberg, Germany., Peyser P; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; University of Turku, Turku, Finland., Reiner AP; Fred Hutchinson Cancer Research Center, University of Washington School of Public Health, Seattle, WA, USA., Rensen PCN; Department of Internal Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Leiden, The Netherlands., Rice TK; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA., Rich SS; Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Roenneberg T; Institute of Medical Psychology, Ludwig-Maximilians-Universitat Munchen, Munich, Germany., Rotter JI; Genomic Outcomes, Department of Pediatrics, Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CC, USA., Schreiner PJ; Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Shikany J; Division of Preventive Medicine, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Sidney SS; Division of Research, Kaiser Permanente Northern California, Oakland, CA, USA., Sims M; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Sitlani CM; Cardiovascular Health Research Unit, Medicine, University of Washington, Seattle, WA, USA., Sofer T; Division of Sleep and Circadian Disorders, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA.; Institute of Human Genetics, Technische Universität München, Munich, Germany., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute for Medical Informatics Biometry and Epidemiology, Ludwig-Maximilians-Universitat Munchen, Munich, Germany., Swertz MA; University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands., Taylor KD; Genomic Outcomes, Department of Pediatrics, Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CC, USA., Uitterlinden AG; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands., van Duijn CM; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Nuffield Department of Population Health, University of Oxford, Oxford, UK., Völzke H; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Waldenberger M; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Neuherberg, Germany., Wallance RB; Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IA, USA., van Dijk KW; Department of Internal Medicine, Division of Endocrinology, Leiden University Medical Center, Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, Leiden, The Netherlands.; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands., Yu C; Department of Occupational and Environmental Health and State Key Laboratory of Environmental Health for Incubating, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Zonderman AB; Behavioral Epidemiology Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Becker DM; Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Elliott P; Department of Biotechnology, Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia.; MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; National Institute of Health Research Imperial College London Biomedical Research Centre, London, UK.; UK-DRI Dementia Research Institute at Imperial College London, London, UK., Esko T; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Boston, MA, USA., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany., Grabe HJ; Department Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany., Lakka TA; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Finland.; Department of Clinical Phsiology and Nuclear Medicine, Kuopia University Hospital, Kuopio, Finland., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., North KE; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Penninx BWJH; Department of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, Amsterdam UMC, Vrije Universiteit, Amsterdam, The Netherlands., Vollenweider P; Medicine, Internal Medicine, Lausanne University Hospital, Lausanne, Switzerland., Wagenknecht LE; Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Wu T; Department of Occupational and Environmental Health and State Key Laboratory of Environmental Health for Incubating, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China., Xiang YB; SKLORG & Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, P. R. China., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA., Arnett DK; Dean's Office, University of Kentucky College of Public Health, Lexington, KS, USA., Bouchard C; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA, USA., Evans MK; Health Disparities Research Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Kardia S; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Kelly TN; Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA., Kritchevsky SB; Sticht Center for Healthy Aging and Rehabilitation, Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, NY, USA.; The Mindich Child Health Development Institute, The Icahn School of Medicine at Mount Sinai, New York, NY, USA., Pereira AC; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo, SP, Brazil., Province M; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Psaty BM; Cardiovascular Health Research Unit, Epidemiology, Medicine and Health Services, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington, Health Research Institute, Seattle, WA, USA., Rotimi C; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, USA., Zhu X; Department of Population Quantitative and Health Sciences, Case Western Reserve University, Cleveland, OH, USA., Amin N; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Cupples LA; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.; NHLBI Framingham Heart Study, Framingham, MA, USA., Fornage M; Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX, USA., Fox EF; Cardiology, Medicine, University of Mississippi Medical Center, Jackson, MS, USA., Guo X; Genomic Outcomes, Department of Pediatrics, Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CC, USA., Gauderman WJ; Biostatistics, Preventive Medicine, University of Southern California, Los Angeles, CA, USA., Rice K; Department of Biostatistics, University of Washington, Seattle, WA, USA., Kooperberg C; Fred Hutchinson Cancer Research Center, University of Washington School of Public Health, Seattle, WA, USA., Munroe PB; Clinical Pharmacology, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Biomedical Research Centre, Queen Mary University of London, London, London, UK., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, TX, USA., Rao DC; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO, USA., van Heemst D; Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands., Redline S; Division of Sleep and Circadian Disorders, Harvard Medical School, Brigham and Women's Hospital, Boston, MA, USA. sredline@bwh.harvard.edu.; Division of Pulmonary Medicine, Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. sredline@bwh.harvard.edu.
Publikováno v:
Nature communications [Nat Commun] 2019 Nov 12; Vol. 10 (1), pp. 5121. Date of Electronic Publication: 2019 Nov 12.
Autor:
Kunkle BW; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA. bkunkle@miami.edu., Grenier-Boley B; Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.; Institut Pasteur de Lille, Lille, France.; Univ. Lille, U1167-Excellence Laboratory LabEx DISTALZ, Lille, France., Sims R; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Damotte V; Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.; Institut Pasteur de Lille, Lille, France.; Univ. Lille, U1167-Excellence Laboratory LabEx DISTALZ, Lille, France., Naj AC; Department of Biostatistics and Epidemiology/Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Boland A; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France., Vronskaya M; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., van der Lee SJ; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Amlie-Wolf A; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Bellenguez C; Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.; Institut Pasteur de Lille, Lille, France.; Univ. Lille, U1167-Excellence Laboratory LabEx DISTALZ, Lille, France., Frizatti A; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Chouraki V; Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.; Institut Pasteur de Lille, Lille, France.; Univ. Lille, U1167-Excellence Laboratory LabEx DISTALZ, Lille, France.; Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA., Martin ER; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA., Sleegers K; Neurodegenerative Brain Diseases Group, Center for Molecular Neurology, VIB, Antwerp, Belgium.; Laboratory for Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium., Badarinarayan N; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Jakobsdottir J; Icelandic Heart Association, Kopavogur, Iceland., Hamilton-Nelson KL; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA., Moreno-Grau S; Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain., Olaso R; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France., Raybould R; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK., Chen Y; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Kuzma AB; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Hiltunen M; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.; Department of Neurology, Kuopio University Hospital, Kuopio, Finland., Morgan T; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Ahmad S; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Vardarajan BN; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, NY, USA.; Department of Neurology, Columbia University, New York, NY, USA., Epelbaum J; UMR 894, Center for Psychiatry and Neuroscience, Inserm, Université Paris Descartes, Paris, France., Hoffmann P; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany.; Division of Medical Genetics, University Hospital and Department of Biomedicine, University of Basel, Basel, Switzerland., Boada M; Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain., Beecham GW; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA., Garnier JG; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France., Harold D; School of Biotechnology, Dublin City University, Dublin, Ireland., Fitzpatrick AL; Department of Family Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA., Valladares O; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Moutet ML; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France., Gerrish A; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK., Smith AV; Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Qu L; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Bacq D; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France., Denning N; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK., Jian X; Brown Foundation Institute of Molecular Medicine, University of Texas Health Sciences Center at Houston, Houston, TX, USA., Zhao Y; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Del Zompo M; Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy., Fox NC; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.; UK Dementia Research Institute at UCL, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK., Choi SH; Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain., Mateo I; Neurology Service and CIBERNED, 'Marqués de Valdecilla' University Hospital (University of Cantabria and IDIVAL), Santander, Spain., Hughes JT; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Adams HH; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Malamon J; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Sanchez-Garcia F; Department of Immunology, Hospital Universitario Doctor Negrín, Las Palmas de Gran Canaria, Spain., Patel Y; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Dombroski BA; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Naranjo MCD; Department of Immunology, Hospital Universitario Doctor Negrín, Las Palmas de Gran Canaria, Spain., Daniilidou M; Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece., Eiriksdottir G; Icelandic Heart Association, Kopavogur, Iceland., Mukherjee S; Department of Medicine, University of Washington, Seattle, WA, USA., Wallon D; Normandie University, UNIROUEN, Inserm U1245, and Rouen University Hospital, Department of Neurology, Department of Genetics and CNR-MAJ, Normandy Center for Genomic and Personalized Medicine, Rouen, France., Uphill J; Department of Neurodegenerative Disease, MRC Prion Unit at UCL, Institute of Prion Diseases, London, UK., Aspelund T; Icelandic Heart Association, Kopavogur, Iceland.; Centre for Public Health, University of Iceland, Reykjavik, Iceland., Cantwell LB; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Garzia F; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France., Galimberti D; Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Neurodegenerative Diseases Unit, Milan, Italy.; University of Milan, Centro Dino Ferrari, Milan, Italy., Hofer E; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University Graz, Graz, Austria.; Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria., Butkiewicz M; Institute for Computational Biology, Department of Population & Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA., Fin B; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France., Scarpini E; Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Neurodegenerative Diseases Unit, Milan, Italy.; University of Milan, Centro Dino Ferrari, Milan, Italy., Sarnowski C; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Bush WS; Institute for Computational Biology, Department of Population & Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA., Meslage S; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France., Kornhuber J; Department of Psychiatry and Psychotherapy, University of Erlangen-Nuremberg, Erlangen, Germany., White CC; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA., Song Y; Institute for Computational Biology, Department of Population & Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA., Barber RC; Department of Pharmacology and Neuroscience, University of North Texas Health Science Center, Fort Worth, TX, USA., Engelborghs S; Laboratory for Neurochemistry and Behavior, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.; Department of Neurology and Memory Clinic, Hospital Network Antwerp, Antwerp, Belgium., Sordon S; Department of Psychiatry and Psychotherapy, University Hospital, Saarland, Germany., Voijnovic D; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Adams PM; Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA., Vandenberghe R; Laboratory for Cognitive Neurology, Department of Neurology, University Hospital and University of Leuven, Leuven, Belgium., Mayhaus M; Department of Psychiatry and Psychotherapy, University Hospital, Saarland, Germany., Cupples LA; Framingham Heart Study, Framingham, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Albert MS; Department of Neurology, Johns Hopkins University, Baltimore, MD, USA., De Deyn PP; Laboratory for Neurochemistry and Behavior, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium.; Department of Neurology and Memory Clinic, Hospital Network Antwerp, Antwerp, Belgium., Gu W; Department of Psychiatry and Psychotherapy, University Hospital, Saarland, Germany., Himali JJ; Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Beekly D; National Alzheimer's Coordinating Center, University of Washington, Seattle, WA, USA., Squassina A; Section of Neuroscience and Clinical Pharmacology, Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy., Hartmann AM; Department of Psychiatry, Martin Luther University Halle-Wittenberg, Halle, Germany., Orellana A; Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain., Blacker D; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA.; Department of Psychiatry, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA., Rodriguez-Rodriguez E; Neurology Service and CIBERNED, 'Marqués de Valdecilla' University Hospital (University of Cantabria and IDIVAL), Santander, Spain., Lovestone S; Department of Psychiatry, University of Oxford, Oxford, UK., Garcia ME; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, MD, USA., Doody RS; Alzheimer's Disease and Memory Disorders Center, Baylor College of Medicine, Houston, TX, USA., Munoz-Fernadez C; Department of Immunology, Hospital Universitario Doctor Negrín, Las Palmas de Gran Canaria, Spain., Sussams R; Division of Clinical Neurosciences, School of Medicine, University of Southampton, Southampton, UK., Lin H; Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, MA, USA., Fairchild TJ; Office of Strategy and Measurement, University of North Texas Health Science Center, Fort Worth, TX, USA., Benito YA; Department of Immunology, Hospital Universitario Doctor Negrín, Las Palmas de Gran Canaria, Spain., Holmes C; Division of Clinical Neurosciences, School of Medicine, University of Southampton, Southampton, UK., Karamujić-Čomić H; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Frosch MP; C.S. Kubik Laboratory for Neuropathology, Massachusetts General Hospital, Charlestown, MA, USA., Thonberg H; Theme Aging, Unit for Hereditary Dementias, Karolinska University Hospital-Solna, Stockholm, Sweden.; Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Alzheimer Research Center, Division of Neurogeriatrics, Solna, Sweden., Maier W; German Center for Neurodegenerative Diseases, Bonn, Germany.; Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany., Roshchupkin G; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Ghetti B; Department of Pathology and Laboratory Medicine, Indiana University, Indianapolis, IN, USA., Giedraitis V; Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden., Kawalia A; Department for Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany., Li S; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Huebinger RM; Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA., Kilander L; Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden., Moebus S; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen, Germany., Hernández I; Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain., Kamboh MI; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Human Genetics, University of Pittsburgh, Pittsburgh, PA, USA.; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh, PA, USA., Brundin R; Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden., Turton J; Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, UK., Yang Q; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Katz MJ; Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA., Concari L; Section of Neuroscience, DIMEC-University of Parma, Parma, Italy.; FERB-Alzheimer Center, Gazzaniga (Bergamo), Italy., Lord J; Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, UK., Beiser AS; Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Keene CD; Department of Pathology, University of Washington, Seattle, WA, USA., Helisalmi S; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.; Department of Neurology, Kuopio University Hospital, Kuopio, Finland., Kloszewska I; Elderly and Psychiatric Disorders Department, Medical University of Lodz, Lodz, Poland., Kukull WA; Department of Epidemiology, University of Washington, Seattle, WA, USA., Koivisto AM; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.; Department of Neurology, Kuopio University Hospital, Kuopio, Finland., Lynch A; Mercer's Institute for Research on Aging, St. James's Hospital and Trinity College, Dublin, Ireland.; St. James's Hospital and Trinity College, Dublin, Ireland., Tarraga L; Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain., Larson EB; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA., Haapasalo A; A.I. Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland., Lawlor B; Mercer's Institute for Research on Aging, St. James's Hospital and Trinity College, Dublin, Ireland.; St. James's Hospital and Trinity College, Dublin, Ireland., Mosley TH; Departments of Medicine, Geriatrics, Gerontology and Neurology, University of Mississippi Medical Center, Jackson, MS, USA., Lipton RB; Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA., Solfrizzi V; Interdisciplinary Department of Medicine, Geriatric Medicine and Memory Unity, University of Bari, Bari, Italy., Gill M; Mercer's Institute for Research on Aging, St. James's Hospital and Trinity College, Dublin, Ireland.; St. James's Hospital and Trinity College, Dublin, Ireland., Longstreth WT Jr; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Neurology, University of Washington, Seattle, WA, USA., Montine TJ; Department of Pathology, University of Washington, Seattle, WA, USA., Frisardi V; Department of Geriatrics, Center for Aging Brain, University of Bari, Bari, Italy., Diez-Fairen M; Fundació per la Recerca Biomèdica i Social Mútua Terrassa, Terrassa, Barcelona, Spain.; Memory Disorders Unit, Department of Neurology, Hospital Universitari Mutua de Terrassa, Terrassa, Barcelona, Spain., Rivadeneira F; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus University Medical Center, Rotterdamt, the Netherlands.; Netherlands Consortium on Health Aging and National Genomics Initiative, Leiden, the Netherlands., Petersen RC; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Deramecourt V; CHU Lille, Memory Center of Lille (Centre Mémoire de Ressources et de Recherche), Lille, France., Alvarez I; Fundació per la Recerca Biomèdica i Social Mútua Terrassa, Terrassa, Barcelona, Spain.; Memory Disorders Unit, Department of Neurology, Hospital Universitari Mutua de Terrassa, Terrassa, Barcelona, Spain., Salani F; Department of Clinical and Behavioral Neurology, Experimental Neuropsychobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy., Ciaramella A; Department of Clinical and Behavioral Neurology, Experimental Neuropsychobiology Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy., Boerwinkle E; School of Public Health, Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Reiman EM; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, USA.; Arizona Alzheimer's Consortium, Phoenix, AZ, USA.; Banner Alzheimer's Institute, Phoenix, AZ, USA.; Department of Psychiatry, University of Arizona, Phoenix, AZ, USA., Fievet N; Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.; Institut Pasteur de Lille, Lille, France.; Univ. Lille, U1167-Excellence Laboratory LabEx DISTALZ, Lille, France., Rotter JI; Institute for Translational Genomics and Population Sciences, Departments of Pediatrics and Medicine, Los Angeles BioMedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA, USA., Reisch JS; Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, TX, USA., Hanon O; University Paris Descartes, EA 4468, AP-HP, Geriatrics Department, Hôpital Broca, Paris, France., Cupidi C; Regional Neurogenetic Centre (CRN), ASP Catanzaro, Lamezia Terme, Italy., Andre Uitterlinden AG; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus University Medical Center, Rotterdamt, the Netherlands.; Netherlands Consortium on Health Aging and National Genomics Initiative, Leiden, the Netherlands., Royall DR; Departments of Psychiatry, Medicine, Family & Community Medicine, South Texas Veterans Health Administration Geriatric Research Education & Clinical Center (GRECC), UT Health Science Center at San Antonio, San Antonio, TX, USA., Dufouil C; University of Bordeaux, Inserm 1219, Bordeaux, France.; Department of Neurology, Bordeaux University Hospital / CHU de Bordeaux, Bordeaux, France., Maletta RG; Regional Neurogenetic Centre (CRN), ASP Catanzaro, Lamezia Terme, Italy., de Rojas I; Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain., Sano M; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Brice A; Inserm U1127, CNRS UMR 7225, Sorbonne Universités, UPMC Université Paris 06, UMRS 1127, Institut du Cerveau et de la Moelle Épinière, Paris, France.; AP-HP, Department of Genetics, Pitié-Salpêtrière Hospital, Paris, France., Cecchetti R; Section of Gerontology and Geriatrics, Department of Medicine, University of Perugia, Perugia, Italy., George-Hyslop PS; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.; Tanz Centre for Research in Neurodegenerative Disease, University of Toronto, Toronto, Ontario, Canada., Ritchie K; Inserm U1061 Neuropsychiatry, La Colombière Hospital, Montpellier, France.; Montpellier University, Montpellier, France.; Department of Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK., Tsolaki M; Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece., Tsuang DW; VA Puget Sound Health Care System/>GRECC, Seattle, WA, USA.; Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA., Dubois B; Institut de la Mémoire et de la Maladie d'Alzheimer and Institut du Cerveau et de la Moelle Épinière, Département de Neurologie, Hôpital de la Pitié-Salpêtrière, Paris, France.; Institut des Neurosciences Translationnelles de Paris, Institut du Cerveau et de la Moelle Épinière, Paris, France.; Inserm, CNRS, UMR-S975, Institut du Cerveau et de la Moelle Epinière, Paris, France.; Sorbonne Universités, Université Pierre et Marie Curie, Hôpital de la Pitié-Salpêtrière, AP-HP, Paris, France., Craig D; Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK., Wu CK; Departments of Neurology, Pharmacology & Neuroscience, Texas Tech University Health Science Center, Lubbock, TX, USA., Soininen H; Institute of Biomedicine, University of Eastern Finland, Kuopio, Finland.; Department of Neurology, Kuopio University Hospital, Kuopio, Finland., Avramidou D; Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece., Albin RL; Department of Neurology, University of Michigan, Ann Arbor, MI, USA.; Geriatric Research, Education and Clinical Center (GRECC), VA Ann Arbor Healthcare System (VAAAHS), Ann Arbor, MI, USA.; Michigan Alzheimer Disease Center, Ann Arbor, MI, USA., Fratiglioni L; Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden., Germanou A; Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece., Apostolova LG; Indiana Alzheimer's Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA.; Department of Medical and Molecular Genetics, Indiana University, Indianapolis, IN, USA.; Department of Neurology, Indiana University, Indianapolis, IN, USA.; Department of Radiology and Imaging Sciences, Indiana University, Indianapolis, IN, USA., Keller L; Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet and Stockholm University, Stockholm, Sweden., Koutroumani M; Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece., Arnold SE; Department of Psychiatry, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Panza F; Department of Geriatrics, Center for Aging Brain, University of Bari, Bari, Italy., Gkatzima O; Department of Neurology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece., Asthana S; Geriatric Research, Education and Clinical Center (GRECC), University of Wisconsin, Madison, WI, USA.; Department of Medicine, University of Wisconsin, Madison, WI, USA.; Wisconsin Alzheimer's Disease Research Center, Madison, WI, USA., Hannequin D; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Whitehead P; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA., Atwood CS; Department of Medical and Molecular Genetics, Indiana University, Indianapolis, IN, USA.; Department of Neurology, Indiana University, Indianapolis, IN, USA.; Department of Radiology and Imaging Sciences, Indiana University, Indianapolis, IN, USA., Caffarra P; Alzheimer's Disease Research Center, University of Pittsburgh, Pittsburgh, PA, USA.; Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, UK., Hampel H; AXA Research Fund & Sorbonne University Chair, Paris, France.; Sorbonne University, GRC n° 21, Alzheimer Precision Medicine (APM), AP-HP, Pitié-Salpêtrière Hospital, Paris, France.; Brain & Spine Institute, Inserm U 1127, CNRS UMR 7225, Paris, France.; Institute of Memory and Alzheimer's Disease, Department of Neurology, Pitié-Salpêtrière Hospital, AP-HP, Paris, France., Quintela I; Grupo de Medicina Xenomica, Universidade de Santiago de Compostela, Centro Nacional de Genotipado, Centro de Investigación Biomédica en Red de Enfermedades Raras, Santiago de Compostela, Spain., Carracedo Á; Grupo de Medicina Xenomica, Universidade de Santiago de Compostela, Centro Nacional de Genotipado, Centro de Investigación Biomédica en Red de Enfermedades Raras, Santiago de Compostela, Spain., Lannfelt L; Department of Public Health and Caring Sciences/Geriatrics, Uppsala University, Uppsala, Sweden., Rubinsztein DC; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.; UK Dementia Research Institute, University of Cambridge, Cambridge, UK., Barnes LL; Department of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.; Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA.; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, IL, USA., Pasquier F; CHU Lille, Memory Center of Lille (Centre Mémoire de Ressources et de Recherche), Lille, France., Frölich L; Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany., Barral S; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, NY, USA.; Department of Neurology, Columbia University, New York, NY, USA., McGuinness B; Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK., Beach TG; Civin Laboratory for Neuropathology, Banner Sun Health Research Institute, Phoenix, AZ, USA., Johnston JA; Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK., Becker JT; Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USA.; Department of Psychology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Passmore P; Ageing Group, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK., Bigio EH; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Schott JM; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK., Bird TD; Department of Neurology, University of Washington, Seattle, WA, USA.; VA Puget Sound Health Care System/>GRECC, Seattle, WA, USA., Warren JD; Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK., Boeve BF; Department of Neurology, Mayo Clinic, Rochester, MN, USA., Lupton MK; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Herston, Queensland, Australia., Bowen JD; Swedish Medical Center, Seattle, WA, USA., Proitsi P; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Boxer A; Department of Neurology, University of California, San Francisco, San Francisco, CA, USA., Powell JF; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Burke JR; Department of Neurology, Duke University, Durham, NC, USA., Kauwe JSK; Departments of Biology, Brigham Young University, Provo, UT, USA., Burns JM; University of Kansas Alzheimer's Disease Center, University of Kansas Medical Center, Kansas City, KS, USA., Mancuso M; Department of Experimental and Clinical Medicine, Neurological Institute, University of Pisa, Pisa, Italy., Buxbaum JD; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bonuccelli U; Department of Experimental and Clinical Medicine, Neurological Institute, University of Pisa, Pisa, Italy., Cairns NJ; Department of Pathology and Immunology, Washington University, St. Louis, MO, USA., McQuillin A; Division of Psychiatry, University College London, London, UK., Cao C; USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, FL, USA., Livingston G; Division of Psychiatry, University College London, London, UK., Carlson CS; Department of Medicine, University of Wisconsin, Madison, WI, USA.; Wisconsin Alzheimer's Disease Research Center, Madison, WI, USA., Bass NJ; Division of Psychiatry, University College London, London, UK., Carlsson CM; Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Hardy J; Department of Molecular Neuroscience, UCL, Institute of Neurology, London, UK., Carney RM; Mental Health & Behavioral Science Service, Bruce W. Carter VA Medical Center, Miami, FL, USA., Bras J; UK Dementia Research Institute at UCL, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK., Carrasquillo MM; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Guerreiro R; UK Dementia Research Institute at UCL, Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK.; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK., Allen M; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Chui HC; Department of Neurology, University of Southern California, Los Angeles, CA, USA., Fisher E; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK., Masullo C; Department of Neurology, Catholic University of Rome, Rome, Italy., Crocco EA; Department of Psychiatry and Behavioral Sciences, Miller School of Medicine, University of Miami, Miami, FL, USA., DeCarli C; Department of Neurology, University of California, Davis, Sacramento, CA, USA., Bisceglio G; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Dick M; Institute for Memory Impairments and Neurological Disorders, University of California, Irvine, Irvine, CA, USA., Ma L; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Duara R; Wien Center for Alzheimer's Disease and Memory Disorders, Mount Sinai Medical Center, Miami Beach, FL, USA., Graff-Radford NR; Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA., Evans DA; Rush Institute for Healthy Aging, Department of Internal Medicine, Rush University Medical Center, Chicago, IL, USA., Hodges A; Department of Old Age Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Faber KM; Indiana Alzheimer's Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA., Scherer M; Department of Primary Medical Care, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany., Fallon KB; Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA., Riemenschneider M; Department of Psychiatry and Psychotherapy, University Hospital, Saarland, Germany., Fardo DW; Sanders-Brown Center on Aging, Department of Biostatistics, University of Kentucky, Lexington, KY, USA., Heun R; Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany., Farlow MR; Department of Neurology, Indiana University, Indianapolis, IN, USA., Kölsch H; Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany., Ferris S; Department of Psychiatry, New York University, New York, NY, USA., Leber M; Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany., Foroud TM; Indiana Alzheimer's Disease Center, Indiana University School of Medicine, Indianapolis, IN, USA., Heuser I; Department of Psychiatry and Psychotherapy, Charité University Medicine, Berlin, Germany., Galasko DR; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA., Giegling I; Department of Psychiatry, Martin Luther University Halle-Wittenberg, Halle, Germany., Gearing M; Department of Pathology and Laboratory Medicine, Emory University, Atlanta, GA, USA.; Emory Alzheimer's Disease Center, Emory University, Atlanta, GA, USA., Hüll M; Department of Psychiatry, University of Freiburg, Freiburg, Germany., Geschwind DH; Neurogenetics Program, University of California, Los Angeles, Los Angeles, CA, USA., Gilbert JR; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA., Morris J; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; Hope Center Program on Protein Aggregation and Neurodegeneration, Washington University School of Medicine, St. Louis, MO, USA., Green RC; Division of Genetics, Department of Medicine and Partners Center for Personalized Genetic Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Mayo K; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, USA.; Department of Neurology, Washington University, St. Louis, MO, USA.; Department of Genetics, Washington University, St. Louis, MO, USA., Growdon JH; Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA., Feulner T; Department of Psychiatry and Psychotherapy, University Hospital, Saarland, Germany., Hamilton RL; Department of Pathology (Neuropathology), University of Pittsburgh, Pittsburgh, PA, USA., Harrell LE; Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA., Drichel D; Cologne Center for Genomics, University of Cologne, Cologne, Germany., Honig LS; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA., Cushion TD; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK., Huentelman MJ; Neurogenomics Division, Translational Genomics Research Institute, Phoenix, AZ, USA., Hollingworth P; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Hulette CM; Department of Pathology, Duke University, Durham, NC, USA., Hyman BT; Department of Neurology, Massachusetts General Hospital/Harvard Medical School, Boston, MA, USA., Marshall R; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Jarvik GP; Department of Genome Sciences, University of Washington, Seattle, WA, USA.; Department of Medicine (Medical Genetics), University of Washington, Seattle, WA, USA., Meggy A; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Abner E; Sanders-Brown Center on Aging, College of Public Health, Department of Epidemiology, University of Kentucky, Lexington, KY, USA., Menzies GE; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK., Jin LW; Unidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario de Valme, Sevilla, Spain., Leonenko G; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Real LM; Unidad Clínica de Enfermedades Infecciosas y Microbiología, Hospital Universitario de Valme, Sevilla, Spain., Jun GR; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA, USA., Baldwin CT; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA, USA., Grozeva D; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Karydas A; Swedish Medical Center, Seattle, WA, USA., Russo G; Functional Genomics Center Zurich, ETH/University of Zurich, Zurich, Switzerland., Kaye JA; Department of Neurology, Oregon Health &Science University, Portland, OR, USA.; Department of Neurology, Portland Veterans Affairs Medical Center, Portland, OR, USA., Kim R; Department of Pathology and Laboratory Medicine, University of California, Irvine, Irvine, CA, USA., Jessen F; German Center for Neurodegenerative Diseases, Bonn, Germany.; Department of Psychiatry and Psychotherapy, University of Bonn, Bonn, Germany.; Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany., Kowall NW; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Department of Pathology, Boston University School of Medicine, Boston University, Boston, MA, USA., Vellas B; Inserm U558, University of Toulouse, Toulouse, France., Kramer JH; Department of Neuropsychology, University of California San Francisco, San Francisco, CA, USA., Vardy E; Institute for Ageing and Health, Newcastle University, Newcastle upon Tyne, UK., LaFerla FM; Department of Neurobiology and Behavior, University of California, Irvine, Irvine, CA, USA., Jöckel KH; Institute for Medical Informatics, Biometry and Epidemiology, University Hospital of Essen, University Duisburg-Essen, Essen, Germany., Lah JJ; Department of Neurology, Emory University, Atlanta, GA, USA., Dichgans M; Institute for Stroke and Dementia Research, Klinikum der Universität München, Munich, Germany.; German Center for Neurodegenerative Diseases, Munich, Germany., Leverenz JB; Cleveland Clinic Lou Ruvo Center for Brain Health, Cleveland Clinic, Cleveland, OH, USA., Mann D; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK., Levey AI; Department of Neurology, Emory University, Atlanta, GA, USA., Pickering-Brown S; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK., Lieberman AP; Department of Pathology, University of Michigan, Ann Arbor, MI, USA., Klopp N; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Munich, Germany., Lunetta KL; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Wichmann HE; Helmholtz Center Munich, Institute of Epidemiology, Neuherberg, Munich, Germany.; Ludwig-Maximilians University Chair of Epidemiology, Munich, Germany.; Joint Biobank Munich and KORA Biobank, Baltimore, MD, USA., Lyketsos CG; Department of Psychiatry, Johns Hopkins University, Baltimore, MD, USA., Morgan K; Human Genetics, Schools of Life Sciences and Medicine, University of Nottingham, Nottingham, UK., Marson DC; Department of Neurology, University of Alabama at Birmingham, Birmingham, AL, USA., Brown K; Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, UK., Martiniuk F; Department of Medicine-Pulmonary, New York University, New York, NY, USA., Medway C; Institute of Genetics, Queen's Medical Centre, University of Nottingham, Nottingham, UK., Mash DC; Department of Neurology, University of Miami, Miami, FL, USA., Nöthen MM; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany., Masliah E; Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.; Department of Pathology, University of California, San Diego, La Jolla, CA, USA., Hooper NM; Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester, UK., McCormick WC; Department of Medicine, University of Washington, Seattle, WA, USA., Daniele A; Institute of Neurology, Catholic University of Sacred Hearth, Rome, Italy., McCurry SM; School of Nursing Northwest Research Group on Aging, University of Washington, Seattle, WA, USA., Bayer A; Institute of Primary Care and Public Health, Cardiff University, University Hospital of Wales, Cardiff, UK., McDavid AN; USF Health Byrd Alzheimer's Institute, University of South Florida, Tampa, FL, USA., Gallacher J; Department of Psychiatry, University of Oxford, Oxford, UK., McKee AC; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Department of Pathology, Boston University School of Medicine, Boston University, Boston, MA, USA., van den Bussche H; Department of Primary Medical Care, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany., Mesulam M; Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Brayne C; Cambridge Institute of Public Health, University of Cambridge School of Clinical Medicine, Cambridge, UK., Miller BL; Weill Institute for Neurosciences, Memory and Aging Center, University of California, San Francisco, San Francisco, CA, USA., Riedel-Heller S; Institute of Social Medicine, Occupational Health and Public Health, University of Leipzig, Leipzig, Germany., Miller CA; Department of Pathology, University of Southern California, Los Angeles, CA, USA., Miller JW; Department of Pathology and Laboratory Medicine, University of California, Davis, Sacramento, CA, USA., Al-Chalabi A; Institute of Psychiatry, Psychology and Neuroscienceó, King's College London, London, UK., Morris JC; 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Clinical Division of Neurogeriatrics, Department of Neurology, Medical University Graz, Graz, Austria., Farrer LA; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA.; Department of Medicine (Biomedical Genetics), Boston University School of Medicine, Boston, MA, USA.; Department of Ophthalmology, Boston University School of Medicine, Boston University, Boston, MA, USA.; Department of Epidemiology, Boston University School of Public Health, Boston, MA, USA., Van Broeckhoven C; Neurodegenerative Brain Diseases Group, Center for Molecular Neurology, VIB, Antwerp, Belgium.; Laboratory for Neurogenetics, Institute Born-Bunge, University of Antwerp, Antwerp, Belgium., C O'Donovan M; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., DeStefano AL; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Jones L; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK., Haines JL; Institute for Computational Biology, Department of Population & Quantitative Health Sciences, Case Western Reserve University, Cleveland, OH, USA., Deleuze JF; Centre National de Recherche en Génomique Humaine, Institut de Biologie François Jacob, CEA, Université Paris-Saclay, and LabEx GENMED, Evry, France., Owen MJ; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Mayeux R; Taub Institute on Alzheimer's Disease and the Aging Brain, Department of Neurology, Columbia University, New York, NY, USA.; 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Sergievsky Center, Columbia University, New York, NY, USA.; Department of Neurology, Columbia University, New York, NY, USA., Escott-Price V; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Health Services, University of Washington, Seattle, WA, USA.; Kaiser Permanente, Washington Health Research Institute, Seattle, WA, USA., Ramirez A; Department for Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Bonn, Germany.; Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany., Wang LS; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Ruiz A; Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades-Universitat Internacional de Catalunya, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas, Instituto de Salud Carlos III, Madrid, Spain., van Duijn CM; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Holmans PA; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Seshadri S; Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA.; Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX, USA., Williams J; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK.; UK Dementia Research Institute at Cardiff, Cardiff University, Cardiff, UK., Amouyel P; Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France.; Institut Pasteur de Lille, Lille, France.; Univ. Lille, U1167-Excellence Laboratory LabEx DISTALZ, Lille, France.; Centre Hospitalier Universitaire de Lille, Lille, France., Schellenberg GD; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA., Lambert JC; Inserm, U1167, RID-AGE-Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France. jean-charles.lambert@pasteur-lille.fr.; Institut Pasteur de Lille, Lille, France. jean-charles.lambert@pasteur-lille.fr.; Univ. Lille, U1167-Excellence Laboratory LabEx DISTALZ, Lille, France. jean-charles.lambert@pasteur-lille.fr., Pericak-Vance MA; John P. Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, Miami, FL, USA. mpericak@miami.edu.
Publikováno v:
Nature genetics [Nat Genet] 2019 Mar; Vol. 51 (3), pp. 414-430. Date of Electronic Publication: 2019 Feb 28.
Autor:
Sabater-Lleal M; Cardiovascular Medicine Unit, Department of Medicine, Karolinska Institutet, Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden (M.S.-L.).; Unit of Genomics of Complex Diseases, Institut d'Investigació Biomèdica Sant Pau, IIB-Sant Pau, Barcelona, Spain (M.S.-L., A.M.-P., J.M.S.)., Huffman JE; Population Sciences Branch, National Heart, Lung, and Blood Institute, Framingham, MA (J.E.H., C.S., J.D.E., M.-H.C., A.D.J., C.J.O.).; Framingham Heart Study, MA (J.E.H., C.S., J.D.E., M.-H.C., A.D.J., C.J.O.)., de Vries PS; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health (P.S.d.V., E.B., M.F., A.C.M.), University of Texas Health Science Center at Houston.; Department of Epidemiology (P.S.d.V., A.H., O.H.F., A.D.), Erasmus University Medical Center, Rotterdam, the Netherlands., Marten J; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine (J.M., J.F.W., C.H.), University of Edinburgh, Scotland., Mastrangelo MA; Aab Cardiovascular Research Institute, University of Rochester Medical Center, NY (M.A.M., C.J.L.)., Song C; Population Sciences Branch, National Heart, Lung, and Blood Institute, Framingham, MA (J.E.H., C.S., J.D.E., M.-H.C., A.D.J., C.J.O.).; Framingham Heart Study, MA (J.E.H., C.S., J.D.E., M.-H.C., A.D.J., C.J.O.)., Pankratz N; Department of Laboratory Medicine and Pathology, University of Minnesota School of Medicine, Minneapolis (N.P.)., Ward-Caviness CK; Environmental Public Health Division, National Health and Environmental Effects Research Laboratory, US Environmental Protection Agency, Chapel Hill, NC (C.K.W.-C.)., Yanek LR; GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD (L.R.Y., D.V., D.M.B., L.C.B.)., Trompet S; Department of Geriatrics and Gerontology (S.T.), Leiden University Medical Center, the Netherlands.; Department of Cardiology (S.T., J.W.J.), Leiden University Medical Center, the Netherlands., Delgado GE; Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany (G.E.D., M.E.K., W.M.)., Guo X; Institute for Translational Genomics and Population Sciences, Department of Pediatrics and Medicine, LABioMed at Harbor-UCLA Medical Center, Torrance, CA (X.G., J.I.R.)., Bartz TM; Department of Biostatistics (T.M.B., B.M.), University of Washington, Seattle., Martinez-Perez A; Unit of Genomics of Complex Diseases, Institut d'Investigació Biomèdica Sant Pau, IIB-Sant Pau, Barcelona, Spain (M.S.-L., A.M.-P., J.M.S.)., Germain M; Institut national de la santé et de la recherche médicale (INSERM), UMR_S 1166, Team Genomics and Pathophysiology of Cardiovascular Diseases, Sorbonne Universités, Université Pierre-et-Marie-Curie, Paris, France (M.G., D.-A.T.).; ICAN Institute for Cardiometabolism and Nutrition, Paris, France (M.G., D.-A.T.)., de Haan HG; Department of Clinical Epidemiology (H.G.d.H., A.v.H.V., F.R.R.), Leiden University Medical Center, the Netherlands., Ozel AB; Department of Human Genetics (A.B.O., J.Z.L., D.G.), University of Michigan, Ann Arbor., Polasek O; Faculty of Medicine, University of Split, Croatia (O.P., I.K.)., Smith AV; School of Public Health, Department of Biostatistics (A.V.S.), University of Michigan, Ann Arbor., Eicher JD; Framingham Heart Study, MA (J.E.H., C.S., J.D.E., M.-H.C., A.D.J., C.J.O.)., Reiner AP; Department of Epidemiology, (A.P.R., B.M.P., N.L.S.), University of Washington, Seattle.; Fred Hutchinson Cancer Research Center, Seattle, WA (A.P.R.)., Tang W; Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis (W.T.)., Davies NM; Medical Research Council Integrative Epidemiology Unit and Bristol Medical School (N.M.D.), University of Bristol, UK., Stott DJ; Academic Section of Geriatrics, Faculty of Medicine (J.D.S.), University of Glasgow, UK., Rotter JI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics and Medicine, LABioMed at Harbor-UCLA Medical Center, Torrance, CA (X.G., J.I.R.)., Tofler GH; Royal North Shore Hospital, University of Sydney, Australia (G.H.T.)., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health (P.S.d.V., E.B., M.F., A.C.M.), University of Texas Health Science Center at Houston.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX (E.B.)., de Maat MPM; Department of Hematology (M.P.M.d.M.), Erasmus University Medical Center, Rotterdam, the Netherlands., Kleber ME; Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany (G.E.D., M.E.K., W.M.).; Institute of Nutrition, Friedrich-Schiller-University Jena, Mannheim, Germany (M.E.K.)., Welsh P; Institute of Cardiovascular and Medical Sciences (P.W.), University of Glasgow, UK., Brody JA; Department of Medicine (J.A.B., B.M.P.), University of Washington, Seattle., Chen MH; Population Sciences Branch, National Heart, Lung, and Blood Institute, Framingham, MA (J.E.H., C.S., J.D.E., M.-H.C., A.D.J., C.J.O.).; Framingham Heart Study, MA (J.E.H., C.S., J.D.E., M.-H.C., A.D.J., C.J.O.)., Vaidya D; GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD (L.R.Y., D.V., D.M.B., L.C.B.)., Soria JM; Unit of Genomics of Complex Diseases, Institut d'Investigació Biomèdica Sant Pau, IIB-Sant Pau, Barcelona, Spain (M.S.-L., A.M.-P., J.M.S.)., Suchon P; Laboratory of Haematology, La Timone Hospital, Marseille, France (P.S., P.-E.M.).; Institut national de la santé et de la recherche médicale (INSERM), UMR_S 1062, Nutrition Obesity and Risk of Thrombosis, Marseille, France (P.S., P.-E.M.)., van Hylckama Vlieg A; Department of Clinical Epidemiology (H.G.d.H., A.v.H.V., F.R.R.), Leiden University Medical Center, the Netherlands., Desch KC; Department of Pediatrics and Communicable Disease (K.D.C.), University of Michigan, Ann Arbor., Kolcic I; Faculty of Medicine, University of Split, Croatia (O.P., I.K.)., Joshi PK; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics (P.K.J., H.C., I.R., J.F.W.), University of Edinburgh, Scotland., Launer LJ; Laboratory of Epidemiology and Population Sciences National Institute on Aging, Bethesda, MD (L.J.L., T.B.H.)., Harris TB; Laboratory of Epidemiology and Population Sciences National Institute on Aging, Bethesda, MD (L.J.L., T.B.H.)., Campbell H; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics (P.K.J., H.C., I.R., J.F.W.), University of Edinburgh, Scotland., Rudan I; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics (P.K.J., H.C., I.R., J.F.W.), University of Edinburgh, Scotland., Becker DM; GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD (L.R.Y., D.V., D.M.B., L.C.B.)., Li JZ; Department of Human Genetics (A.B.O., J.Z.L., D.G.), University of Michigan, Ann Arbor., Rivadeneira F; Department of Internal Medicine (F.R., A.G.U.), Erasmus University Medical Center, Rotterdam, the Netherlands., Uitterlinden AG; Department of Internal Medicine (F.R., A.G.U.), Erasmus University Medical Center, Rotterdam, the Netherlands., Hofman A; Department of Epidemiology (P.S.d.V., A.H., O.H.F., A.D.), Erasmus University Medical Center, Rotterdam, the Netherlands.; Department of Epidemiology, Harvard H.T. Chan School of Public Health, Boston, MA (A.H.)., Franco OH; Department of Epidemiology (P.S.d.V., A.H., O.H.F., A.D.), Erasmus University Medical Center, Rotterdam, the Netherlands.; Institute of Social and Preventive Medicine, University of Bern, Switzerland (O.H.F.)., Cushman M; Larner College of Medicine, University of Vermont, Colchester (M.C.)., Psaty BM; Department of Epidemiology, (A.P.R., B.M.P., N.L.S.), University of Washington, Seattle.; Department of Medicine (J.A.B., B.M.P.), University of Washington, Seattle.; Department of Health Services (B.M.P.), University of Washington, Seattle.; Kaiser Permanente Washington Research Institute, Kaiser Permanente Washington, Seattle (B.M.P., N.L.S.)., Morange PE; Laboratory of Haematology, La Timone Hospital, Marseille, France (P.S., P.-E.M.).; Institut national de la santé et de la recherche médicale (INSERM), UMR_S 1062, Nutrition Obesity and Risk of Thrombosis, Marseille, France (P.S., P.-E.M.)., McKnight B; Department of Biostatistics (T.M.B., B.M.), University of Washington, Seattle.; Cardiovascular Health Research Unit (B.M.), University of Washington, Seattle., Chong MR; McMaster University, Population Health Research Institute, Population Health Research Institute, Biochemistry and Biomedical Sciences, Hamilton, Canada (M.R.C.)., Fernandez-Cadenas I; Stroke Pharmacogenomics and genetics, Department of Neurology, Institut d'Investigació Biomedica Sant Pau, IIB-Sant Pau, Barcelona, Spain (I.F.-C.)., Rosand J; Massachusetts General Hospital, Broad Institute, Harvard Medical School, Boston (J.R.)., Lindgren A; Department of Clinical Sciences Lund, Neurology, Lund University, Sweden (A.L.).; Department of Neurology and Rehabilitation Medicine, Neurology, Skåne University Hospital, Lund, Sweden (A.L.)., Gudnason V; Icelandic Heart Association, Kopavogur (V.G.).; Faculty of Medicine, University of Iceland, Reykjavik (V.G.)., Wilson JF; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine (J.M., J.F.W., C.H.), University of Edinburgh, Scotland.; Centre for Global Health Research, Usher Institute for Population Health Sciences and Informatics (P.K.J., H.C., I.R., J.F.W.), University of Edinburgh, Scotland., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine (J.M., J.F.W., C.H.), University of Edinburgh, Scotland., Ginsburg D; Department of Human Genetics (A.B.O., J.Z.L., D.G.), University of Michigan, Ann Arbor., Fornage M; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health (P.S.d.V., E.B., M.F., A.C.M.), University of Texas Health Science Center at Houston.; Brown Foundation Institute of Molecular Medicine (M.F.), University of Texas Health Science Center at Houston., Rosendaal FR; Department of Clinical Epidemiology (H.G.d.H., A.v.H.V., F.R.R.), Leiden University Medical Center, the Netherlands.; Einthoven Laboratory of Experimental Vascular Medicine (F.R.R., J.W.J.), Leiden University Medical Center, the Netherlands., Souto JC; Unit of Hemostasis and Thrombosis, Hospital de la Sant Creu i Sant Pau, Barcelona, Spain (J.C.S.)., Becker LC; GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD (L.R.Y., D.V., D.M.B., L.C.B.)., Jenny NS; Department of Pathology and Laboratory Medicine, University of Vermont College of Medicine, Colchester (N.S.J.)., März W; Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany (G.E.D., M.E.K., W.M.).; SYNLAB Academy, SYNLAB Holding Deutschland GmbH, Mannheim, Germany (W.M.).; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University Graz, Mannheim, Germany (W.M.)., Jukema JW; Department of Cardiology (S.T., J.W.J.), Leiden University Medical Center, the Netherlands.; Einthoven Laboratory of Experimental Vascular Medicine (F.R.R., J.W.J.), Leiden University Medical Center, the Netherlands.; Interuniversity Cardiology Institute of the Netherlands, Utrecht (J.W.J.)., Dehghan A; Department of Epidemiology (P.S.d.V., A.H., O.H.F., A.D.), Erasmus University Medical Center, Rotterdam, the Netherlands.; Department of Epidemiology and Biostatistics, Imperial College London, UK (A.D.)., Trégouët DA; Institut national de la santé et de la recherche médicale (INSERM), UMR_S 1166, Team Genomics and Pathophysiology of Cardiovascular Diseases, Sorbonne Universités, Université Pierre-et-Marie-Curie, Paris, France (M.G., D.-A.T.).; ICAN Institute for Cardiometabolism and Nutrition, Paris, France (M.G., D.-A.T.)., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics and Environmental Sciences, School of Public Health (P.S.d.V., E.B., M.F., A.C.M.), University of Texas Health Science Center at Houston., Johnson AD; Population Sciences Branch, National Heart, Lung, and Blood Institute, Framingham, MA (J.E.H., C.S., J.D.E., M.-H.C., A.D.J., C.J.O.).; Framingham Heart Study, MA (J.E.H., C.S., J.D.E., M.-H.C., A.D.J., C.J.O.)., O'Donnell CJ; Population Sciences Branch, National Heart, Lung, and Blood Institute, Framingham, MA (J.E.H., C.S., J.D.E., M.-H.C., A.D.J., C.J.O.).; Framingham Heart Study, MA (J.E.H., C.S., J.D.E., M.-H.C., A.D.J., C.J.O.).; Cardiology Section Administration, Boston VA Healthcare System, West Roxbury, MA (C.J.O.)., Strachan DP; Population Health Research Institute, St George's, University of London, UK (D.P.S.)., Lowenstein CJ; Aab Cardiovascular Research Institute, University of Rochester Medical Center, NY (M.A.M., C.J.L.)., Smith NL; Department of Epidemiology, (A.P.R., B.M.P., N.L.S.), University of Washington, Seattle.; Kaiser Permanente Washington Research Institute, Kaiser Permanente Washington, Seattle (B.M.P., N.L.S.).; Seattle Epidemiologic Research and Information Center, Department of Veterans Affairs Office of Research and Development, WA (N.L.S.).
Publikováno v:
Circulation [Circulation] 2019 Jan 29; Vol. 139 (5), pp. 620-635.
Autor:
Kilpeläinen TO; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200, Denmark. tuomas.kilpelainen@sund.ku.dk.; Department of Environmental Medicine and Public Health, The Icahn School of Medicine at Mount Sinai, New York, 10029, NY, USA. tuomas.kilpelainen@sund.ku.dk., Bentley AR; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, 20892, MD, USA., Noordam R; Internal Medicine, Gerontology and Geriatrics, Leiden University Medical Center, Leiden, 2300 RC, The Netherlands., Sung YJ; Division of Biostatistics, Washington University School of Medicine, St. Louis, 63110, MO, USA., Schwander K; Division of Biostatistics, Washington University School of Medicine, St. Louis, 63110, MO, USA., Winkler TW; Department of Genetic Epidemiology, University of Regensburg, Regensburg, 93051, Germany., Jakupović H; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200, Denmark., Chasman DI; Preventive Medicine, Brigham and Women's Hospital, Boston, 02215, MA, USA.; Harvard Medical School, Boston, 02131, MA, USA., Manning A; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital, Boston, 02114, MA, USA.; Department of Medicine, Harvard Medical School, Boston, 02115, MA, USA., Ntalla I; Clinical Pharmacology, William Harvey Research Instititute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK., Aschard H; Department of Epidemiology, Harvard School of Public Health, Boston, 02115, MA, USA.; Centre de Bioinformatique, Biostatistique et Biologie Intégrative (C3BI), Institut Pasteur, Paris, 75015, France., Brown MR; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, 77030, TX, USA., de Las Fuentes L; Division of Biostatistics, Washington University School of Medicine, St. Louis, 63110, MO, USA.; Cardiovascular Division, Department of Medicine, Washington University, St. Louis, 63110, MO, USA., Franceschini N; Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, 27514, NC, USA., Guo X; The Institute for Translational Genomics and Population Sciences, Division of Genomic Outcomes, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, 90502, CA, USA., Vojinovic D; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CE, The Netherlands., Aslibekyan S; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, 35294, AL, USA., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, 63108, MO, USA., Kho M; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, 48109, MI, USA., Musani SK; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, 39213, MS, USA., Richard M; Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, 77030, TX, USA., Wang H; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, 02115, MA, USA., Wang Z; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, 77030, TX, USA., Bartz TM; Cardiovascular Health Research Unit, Biostatistics and Medicine, University of Washington, Seattle, 98101, WA, USA., Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, 48109, MI, USA., Campbell A; Centre for Genomic & Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Dorajoo R; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, 138672, Singapore., Fisher V; Biostatistics, Boston University School of Public Health, Boston, 02118, MA, USA., Hartwig FP; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, 96020220, RS, Brazil.; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol, BS8 2BN, UK., Horimoto ARVR; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo, 01246903, SP, Brazil., Li C; Epidemiology and Biostatistics, University of Giorgia at Athens College of Public Health, Athens, 30602, GA, USA., Lohman KK; Public Health Sciences, Biostatistical Sciences, Wake Forest University Health Sciences, Winston-Salem, 27157, NC, USA., Marten J; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Sim X; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, 117549, Singapore., Smith AV; Icelandic Heart Association, 201, Kopavogur, Iceland.; Department of Biostatistics, University of Michigan, Ann Arbor, 48109, MI, USA., Tajuddin SM; Health Disparities Research Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, 21224, MD, USA., Alver M; Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia., Amini M; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands., Boissel M; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, 59000, France., Chai JF; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, 117549, Singapore., Chen X; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Stockholm, 17177, Sweden., Divers J; Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, 27157, NC, USA., Evangelou E; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, 45110, Greece., Gao C; Molecular Genetics and Genomics Program, Wake Forest School of Medicine, Winston-Salem, 27157, NC, USA., Graff M; Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, 27514, NC, USA., Harris SE; Centre for Genomic & Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., He M; Department of Occupational and Environmental Health and State Key Laboratory of Environmental Health for Incubating, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430014, China., Hsu FC; Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, 27157, NC, USA., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, 48109, MI, USA., Zhao JH; MRC Epidemiology Unit, University of Cambridge, Cambridge, CB2 0QQ, UK., Kraja AT; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, 63108, MO, USA., Kühnel B; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, 85764, Germany., Laguzzi F; Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, 17177, Sweden., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, 33014, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33014, Finland., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands., Rauramaa R; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, 70100, Finland., Riaz M; College of Medicine, Biological Sciences and Psychology, Health Sciences, The Infant Mortality and Morbidity Studies (TIMMS), Leicester, LE1 7RH, UK., Robino A; Institute for Maternal and Child Health-IRCCS 'Burlo Garofolo', Trieste, 34137, Italy., Rueedi R; Department of Computational Biology, University of Lausanne, Lausanne, 1015, Switzerland.; Swiss Institute of Bioinformatics, 1015, Lausanne, Switzerland., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, 48109, MI, USA., Takeuchi F; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, 1628655, Japan., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands., Varga TV; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Skåne University Hospital, Malmö, 20502, Sweden., Verweij N; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, 9700 RB, The Netherlands., Ware EB; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, 48104, MI, USA., Wen W; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, 37203, TN, USA., Li X; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, 44106, OH, USA., Yanek LR; Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, 21287, MD, USA., Amin N; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CE, The Netherlands., Arnett DK; Dean's Office, University of Kentucky College of Public Health, Lexington, 40536, KY, USA., Boerwinkle E; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, 77030, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, 77030, TX, USA., Brumat M; Department of Medical Sciences, University of Trieste, Trieste, 34137, Italy., Cade B; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, 02115, MA, USA., Canouil M; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, 59000, France., Chen YI; The Institute for Translational Genomics and Population Sciences, Division of Genomic Outcomes, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, 90502, CA, USA., Concas MP; Institute for Maternal and Child Health-IRCCS 'Burlo Garofolo', Trieste, 34137, Italy., Connell J; Ninewells Hospital & Medical School, University of Dundee, Dundee, DD1 9SY, Scotland, UK., de Mutsert R; Clinical Epidemiology, Leiden University Medical Center, Leiden, 2300 RC, Netherlands., de Silva HJ; Department of Medicine, Faculty of Medicine, University of Kelaniya, Ragama, 11600, Sri Lanka., de Vries PS; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, 77030, TX, USA., Demirkan A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CE, The Netherlands., Ding J; Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, 27157, NC, USA., Eaton CB; Department of Family Medicine and Epidemiology, Alpert Medical School of Brown University, Providence, 02860, RI, USA., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, 48104, MI, USA., Friedlander Y; Braun School of Public Health, Hebrew University-Hadassah Medical Center, Jerusalem, 91120, Israel., Gabriel KP; Department of Epidemiology, Human Genetics & Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Austin, Austin, 78712, TX, USA., Ghanbari M; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CE, The Netherlands.; Department of Genetics, School of Medicine, Mashhad University of Medical Sciences, Mashhad, 91778-99191, Iran., Giulianini F; Preventive Medicine, Brigham and Women's Hospital, Boston, 02215, MA, USA., Gu CC; Division of Biostatistics, Washington University School of Medicine, St. Louis, 63110, MO, USA., Gu D; Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100006, China., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Bethesda, 20892, MD, USA., He J; Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, 70112, LA, USA.; Medicine, Tulane University School of Medicine, New Orleans, 70112, LA, USA., Heikkinen S; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, 70211, Finland.; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, 70210, Finland., Heng CK; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore.; Khoo Teck Puat-National University Children's Medical Institute, National University Health System, Singapore, 119228, Singapore., Hunt SC; Division of Epidemiology, Department of Internal Medicine, University of Utah, Salt Lake City, 84132, UT, USA.; Department of Genetic Medicine, Weill Cornell Medicine, Doha, 24144, Qatar., Ikram MA; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CE, The Netherlands.; Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, 3015 GD, The Netherlands., Jonas JB; Department of Ophthalmology, Medical Faculty Mannheim, University Heidelberg, Mannheim, 68167, Germany.; Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Ophthalmology and Visual Science Key Lab, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China., Koh WP; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, 117549, Singapore.; Health Services and Systems Research, Duke-NUS Medical School, Singapore, 169857, Singapore., Komulainen P; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, 70100, Finland., Krieger JE; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo, 01246903, SP, Brazil., Kritchevsky SB; Department of Internal Medicine, Section on Gerontology and Geriatric Medicine, Wake Forest School of Medicine, Winston-Salem, 27157, NC, USA., Kutalik Z; Swiss Institute of Bioinformatics, 1015, Lausanne, Switzerland.; Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, 1010, Switzerland., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, 70210, Finland., Langefeld CD; Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, 27157, NC, USA., Langenberg C; MRC Epidemiology Unit, University of Cambridge, Cambridge, CB2 0QQ, UK., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Bethesda, 20892, MD, USA., Leander K; Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, 17177, Sweden., Lemaitre RN; Cardiovascular Health Research Unit, Medicine, University of Washington, Seattle, 98101, WA, USA., Lewis CE; Division of Preventive Medicine, Department of Medicine, University of Alabama at Birmingham, School of Medicine, Birmingham, 35294, AL, USA., Liang J; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, 44106, OH, USA., Liu J; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore, 138672, Singapore.; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117597, Singapore., Mägi R; Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia., Manichaikul A; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, 22908, VA, USA., Meitinger T; Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Institute of Human Genetics, Technische Universität München, Munich, 80333, Germany., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia., Milaneschi Y; Department of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, VU University Medical Center, Amsterdam, 1081 HV, The Netherlands., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, 27514, NC, USA., Mosley TH Jr; Geriatrics, Medicine, University of Mississippi, Jackson, 39216, MS, USA., Murray AD; The Institute of Medical Sciences, Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen, AB25 2ZD, UK., Nalls MA; Molecular Genetics Section, Laboratory of Neurogenetics, National Institute on Aging, Bethesda, 20892, MD, USA.; Data Tecnica International, Glen Echo, 20812, MD, USA., Nang EK; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, 117549, Singapore., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Leicester, LE3 9PQ, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, LE3 9QD, UK., Nona S; Cardiovascular Health Research Unit, Division of Cardiology, University of Washington, Seattle, 98101, WA, USA., Norris JM; Department of Epidemiology, University of Colorado Denver, Aurora, 80045, CO, USA., Nwuba CV; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, 2200, Denmark., O'Connell J; Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, 21201, MD, USA.; Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, 21201, MD, USA., Palmer ND; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, 27157, NC, USA., Papanicolau GJ; Epidemiology Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, 20892, MD, USA., Pazoki R; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Stockholm, 17177, Sweden., Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, 85764, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Neuherberg, 85764, Germany., Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, 48109, MI, USA., Polasek O; Department of Public Health, Department of Medicine, University of Split, Split, 21000, Croatia.; Psychiatric Hospital 'Sveti Ivan', Zagreb, 10000, Croatia.; Gen-Info Ltd., 10000, Zagreb, Croatia., Porteous DJ; Centre for Genomic & Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Poveda A; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Skåne University Hospital, Malmö, 20502, Sweden., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, 20521, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, 20520, Finland., Rich SS; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, 22908, VA, USA., Risch N; Institute for Human Genetics, Department of Epidemiology and Biostatistics, University of California, San Francisco, 94143, CA, USA., Robinson JG; Department of Epidemiology and Medicine, University of Iowa, Iowa City, 52242, IA, USA., Rose LM; Preventive Medicine, Brigham and Women's Hospital, Boston, 02215, MA, USA., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, EH16 4UX, UK., Schreiner PJ; Division of Epidemiology & Community Health, School of Public Health, University of Minnesota, Minneapolis, 55454, MN, USA., Scott RA; MRC Epidemiology Unit, University of Cambridge, Cambridge, CB2 0QQ, UK., Sidney SS; Kaiser Permanente Washington, Health Research Institute, Seattle, 98101, WA, USA., Sims M; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, 39213, MS, USA., Smith JA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, 48109, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, 48104, MI, USA., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands., Sofer T; Department of Medicine, Harvard Medical School, Boston, 02115, MA, USA.; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, 02115, MA, USA., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Alzheimer Scotland Dementia Research Centre, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Sternfeld B; Kaiser Permanente Washington, Health Research Institute, Seattle, 98101, WA, USA., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Institute of Medical Informatics Biometry and Epidemiology, Ludwig-Maximilians-Universitat Munchen, Munich, 81377, Germany., Tang H; Department of Genetics, Stanford University, Stanford, 94305, CA, USA., Taylor KD; The Institute for Translational Genomics and Population Sciences, Division of Genomic Outcomes, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, 90502, CA, USA., Tsai MY; Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, 55455, MN, USA., Tuomilehto J; Public Health Solutions, National Institute for Health and Welfare, Helsinki, 00271, Finland.; Diabetes Research Group, King Abdulaziz University, Jeddah, 21589, Saudi Arabia., Uitterlinden AG; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, 3015 CE, The Netherlands., van der Ende MY; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, 9700 RB, The Netherlands., van Heemst D; Internal Medicine, Gerontology and Geriatrics, Leiden University Medical Center, Leiden, 2300 RC, The Netherlands., Voortman T; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CE, The Netherlands., Waldenberger M; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, 85764, Germany.; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, 85764, Germany., Wennberg P; Department of Public Health & Clinical Medicine, Umeå University, Umeå, 90185, Västerbotten, Sweden., Wilson G; Jackson Heart Study, School of Public Health, Jackson State University, Jackson, 39213, MS, USA., Xiang YB; State Key Laboratory of Oncogene and Related Genes & Department of Epidemiology, Shanghai Cancer Institute, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, 200000, China., Yao J; The Institute for Translational Genomics and Population Sciences, Division of Genomic Outcomes, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, 90502, CA, USA., Yu C; Department of Occupational and Environmental Health and State Key Laboratory of Environmental Health for Incubating, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430014, China., Yuan JM; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, 15261, PA, USA.; Division of Cancer Control and Population Sciences, UPMC Hillman Cancer, University of Pittsburgh, Pittsburgh, 15232, PA, USA., Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, 48109, MI, USA., Zonderman AB; Behavioral Epidemiology Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, 21224, MD, USA., Becker DM; Division of General Internal Medicine, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, 21287, MD, USA., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, 48109, MI, USA., Bowden DW; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, 27157, NC, USA., de Faire U; Unit of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, 17177, Sweden., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh, EH8 9JZ, UK.; Psychology, The University of Edinburgh, Edinburgh, EH8 9JZ, UK., Elliott P; Department of Epidemiology and Biostatistics, Imperial College London, London, W2 1PG, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, W2 1PG, UK., Esko T; Estonian Genome Center, University of Tartu, Tartu, 51010, Estonia.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Boston, 02142, MA, USA., Freedman BI; Section on Nephrology, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, 27157, NC, USA., Froguel P; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille, 59000, France.; Department of Genomics of Common Disease, Imperial College London, London, W12 0NN, UK., Gasparini P; Institute for Maternal and Child Health-IRCCS 'Burlo Garofolo', Trieste, 34137, Italy.; Department of Medical Sciences, University of Trieste, Trieste, 34137, Italy., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, 85764, Germany.; German Center for Diabetes Research (DZD e.V.), Neuherberg, 85764, Germany., Kato N; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, 1628655, Japan., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, 70210, Finland., Lakka TA; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, 70100, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, 70211, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, 70210, Finland., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, 33014, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, 33014, Finland., Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Stockholm, 17177, Sweden., Oldehinkel AJ; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, 9713 GZ, The Netherlands., Penninx BWJH; Department of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, VU University Medical Center, Amsterdam, 1081 HV, The Netherlands., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, LE3 9PQ, UK.; NIHR Leicester Biomedical Research Centre, Glenfield Hospital, Leicester, LE3 9QD, UK., Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, 37203, TN, USA., van der Harst P; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen, 9700 RB, The Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, 9700 RB, The Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, 1105 AZ, The Netherlands., Van Vliet-Ostaptchouk JV; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, 9713 GZ, The Netherlands., Vollenweider P; Internal Medicine, Department of Medicine, Lausanne University Hospital, Lausanne, 1011, Switzerland., Wagenknecht LE; Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, 27157, NC, USA., Wang YX; Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Ophthalmology and Visual Science Key Lab, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China., Wareham NJ; MRC Epidemiology Unit, University of Cambridge, Cambridge, CB2 0QQ, UK., Weir DR; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, 48104, MI, USA., Wu T; Department of Occupational and Environmental Health and State Key Laboratory of Environmental Health for Incubating, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430014, China., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, 37203, TN, USA., Zhu X; Department of Population and Quantitative Health Sciences, Case Western Reserve University, Cleveland, 44106, OH, USA., Evans MK; Health Disparities Research Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, 21224, MD, USA., Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University Diabetes Centre, Skåne University Hospital, Malmö, 20502, Sweden.; Department of Public Health & Clinical Medicine, Umeå University, Umeå, 90185, Västerbotten, Sweden.; Harvard T. H. Chan School of Public Health, Department of Nutrition, Harvard University, Boston, 02115, MA, USA.; OCDEM, Radcliffe Department of Medicine, University of Oxford, Oxford, OX3 7LE, UK., Gudnason V; Icelandic Heart Association, 201, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, 101, Iceland., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics and Molecular Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, EH4 2XU, UK., Horta BL; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, 96020220, RS, Brazil., Kelly TN; Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, 70112, LA, USA., Liu Y; Public Health Sciences, Epidemiology and Prevention, Wake Forest University Health Sciences, Winston-Salem, 27157, NC, USA., North KE; Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, 27514, NC, USA., Pereira AC; Laboratory of Genetics and Molecular Cardiology, Heart Institute (InCor), University of São Paulo Medical School, São Paulo, 01246903, SP, Brazil., Ridker PM; Preventive Medicine, Brigham and Women's Hospital, Boston, 02215, MA, USA.; Harvard Medical School, Boston, 02131, MA, USA., Tai ES; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, 117549, Singapore.; Health Services and Systems Research, Duke-NUS Medical School, Singapore, 169857, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore., van Dam RM; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, 117549, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore., Fox ER; Cardiology, Medicine, University of Mississippi Medical Center, Jackson, 39216, MS, USA., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, 48109, MI, USA., Liu CT; Biostatistics, Boston University School of Public Health, Boston, 02118, MA, USA., Mook-Kanamori DO; Clinical Epidemiology, Leiden University Medical Center, Leiden, 2300 RC, Netherlands.; Public Health and Primary Care, Leiden University Medical Center, Leiden, 2300 RC, The Netherlands., Province MA; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, 63108, MO, USA., Redline S; Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, 02115, MA, USA., van Duijn CM; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, 3015 CE, The Netherlands., Rotter JI; The Institute for Translational Genomics and Population Sciences, Division of Genomic Outcomes, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, 90502, CA, USA., Kooperberg CB; Fred Hutchinson Cancer Research Center, University of Washington School of Public Health, Seattle, 98109, WA, USA., Gauderman WJ; Biostatistics, Preventive Medicine, University of Southern California, Los Angeles, 90032, CA, USA., Psaty BM; Kaiser Permanente Washington, Health Research Institute, Seattle, 98101, WA, USA.; Cardiovascular Health Research Unit, Epidemiology, Medicine and Health Services, University of Washington, Seattle, 98101, WA, USA., Rice K; Department of Biostatistics, University of Washington, Seattle, 98105, WA, USA., Munroe PB; Clinical Pharmacology, William Harvey Research Instititute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, EC1M 6BQ, UK.; NIHR Barts Cardiovascular Research Centre, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, EC1M 6BQ, UK., Fornage M; Institute of Molecular Medicine, McGovern Medical School, University of Texas Health Science Center at Houston, Houston, 77030, TX, USA., Cupples LA; Biostatistics, Boston University School of Public Health, Boston, 02118, MA, USA.; NHLBI Framingham Heart Study, Framingham, 01702, MA, USA., Rotimi CN; Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, 20892, MD, USA., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, The University of Texas Health Science Center at Houston, Houston, 77030, TX, USA., Rao DC; Division of Biostatistics, Washington University School of Medicine, St. Louis, 63110, MO, USA. rao@wustl.edu., Loos RJF; Icahn School of Medicine at Mount Sinai, The Charles Bronfman Institute for Personalized Medicine, New York, 10029, NY, USA. ruth.loos@mssm.edu.; Icahn School of Medicine at Mount Sinai, The Mindich Child Health and Development Institute, New York, 10029, NY, USA. ruth.loos@mssm.edu.
Publikováno v:
Nature communications [Nat Commun] 2019 Jan 22; Vol. 10 (1), pp. 376. Date of Electronic Publication: 2019 Jan 22.
Autor:
Syme C; The Hospital for Sick Children (C.S., J.S., Z.P.).; Departments of Physiology and Nutritional Sciences (C.S., J.S., Z.P.)., Shin J; The Hospital for Sick Children (C.S., J.S., Z.P.).; Departments of Physiology and Nutritional Sciences (C.S., J.S., Z.P.)., Richer L; Department of Health Sciences, Université du Québec à Chicoutimi, Canada (L.R.)., Gaudet D; Community Genomic Centre, Université de Montréal, Chicoutimi, Canada (D.G.)., Fornage M; University of Texas Health Science Center at Houston (M.F.)., Paus T; Departments of Psychology and Psychiatry, University of Toronto, Canada (T.P.).; Bloorview Research Institute, Toronto, Canada (T.P.)., Pausova Z; The Hospital for Sick Children (C.S., J.S., Z.P.).; Departments of Physiology and Nutritional Sciences (C.S., J.S., Z.P.).
Publikováno v:
Circulation. Genomic and precision medicine [Circ Genom Precis Med] 2019 Jan; Vol. 12 (1), pp. e002341.
Autor:
Ligthart S; Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CA, the Netherlands., Vaez A; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands; Department of Bioinformatics, Isfahan University of Medical Sciences, Isfahan 81746-73461, Iran., Võsa U; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu 51010, Estonia., Stathopoulou MG; Université de Lorraine, INSERM, IGE-PCV, 54000 Nancy, France., de Vries PS; Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CA, the Netherlands; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Prins BP; Department of Human Genetics, Wellcome Trust Sanger Institute, Hinxton CB10 1SA, UK., Van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands., Tanaka T; Translational Gerontology Branch, National Institute on Aging, Baltimore, MD 21224, USA., Naderi E; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands; Department of Radiation Oncology, University of Groningen, University Medical Center Groningen, Groningen 9713 GZ, the Netherlands., Rose LM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA., Wu Y; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA., Karlsson R; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden., Barbalic M; University of Split School of Medicine, Split 21000, Croatia., Lin H; Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA., Pool R; Department of Biological Psychology, Netherlands Twin Register, Vrije Universiteit, Amsterdam 1081 BT, the Netherlands; Amsterdam Public Health research institute, VU University Medical Center, Amsterdam 1081 BT, the Netherlands., Zhu G; QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia., Macé A; Department of Computational Biology, University of Lausanne, Lausanne 1010, Switzerland; Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland; Institute of Social and Preventive Medicine, University Hospital of Lausanne, Lausanne 1010, Switzerland., Sidore C; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche, Sardinia 08045, Italy., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden 2300 RC, the Netherlands; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden 2333 ZA, the Netherlands., Mangino M; Department of Twin Research & Genetic Epidemiology, King's College London, London SE1 7EH, UK; NIHR Biomedical Research Centre at Guy's and St. Thomas' Foundation Trust, London SE1 9RT, UK., Sabater-Lleal M; Unit of Genomics of Complex Diseases, Institut d'Investigació Biomèdica Sant Pau, Barcelona 08025, Spain; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, Stockholm 17176, Sweden., Kemp JP; University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, QLD 4102, Australia; MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol BS8 2BN, UK., Abbasi A; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands; Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen 9713 GZ, the Netherlands; MRC Epidemiology Unit, University of Cambridge School of Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Addenbrooke's Hospital, Cambridge CB2 0QQ, UK., Kacprowski T; Department of Functional Genomics, Interfaculty Institute for Genetics and Functional Genomics, University Medicine and Ernst-Moritz-Arndt University Greifswald, Greifswald 17475, Germany; German Centre for Cardiovascular Research, Partner Site Greifswald, Greifswald 17475, Germany., Verweij N; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen 9713 AV, the Netherlands., Smith AV; Icelandic Heart Association, Kopavogur 201, Iceland; Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland., Huang T; Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Marzi C; Institute of Epidemiology II, Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; German Center for Diabetes Research, Partner Site Munich, Munich 85764, Germany., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO 63108-2212, USA., Lohman KK; Department of Epidemiology and Prevention, Public Health Sciences, Wake Forest University Health Sciences, Winston-Salem, NC 27157, USA., Kleber ME; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim 68167, Germany., Milaneschi Y; Department of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, Amsterdam University Medical Center/GGZ inGeest Research & Innovation, Amsterdam 1081 HJ, the Netherlands., Mueller C; Department of General and Interventional Cardiology, University Heart Center Hamburg, Hamburg 20246, Germany; Institute of Medical Biometry and Statistics, University Medical Center Schleswig-Holstein, Campus Luebeck, Lübeck 23562, Germany; German Center for Cardiovascular Research, Partner Site RhineMain, 55131 Mainz, Germany., Huq M; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands., Vlachopoulou E; Transplantation Laboratory, Medicum, University of Helsinki, Helsinki 00014, Finland., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33014, Finland; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere 33520, Finland., Oldmeadow C; Hunter Medical Research Institute, New Lambon Heights, NSW 2305, Australia; Centre for Clinical Epidemiology & Biostatistics, Faculty of Health and Medicine, University of Newcastle, Callaghan, NSW 2308, Australia., Deelen J; Molecular Epidemiology, Leiden University Medical Center, Leiden 2333 ZC, the Netherlands; Max Planck Institute for Biology of Ageing, Cologne 50931, Germany., Perola M; National Institute for Health and Welfare, Helsinki 00271, Finland., Zhao JH; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK., Feenstra B; Department of Epidemiology Research, Statens Serum Institut, Copenhagen 2300, Denmark., Amini M; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands., Lahti J; Helsinki Collegium for Advanced Studies, University of Helsinki, Helsinki 00014, Finland; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki 00014, Finland; Folkhälsan Research Centre, Helsinki 00250, Finland., Schraut KE; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH16 4UX, UK., Fornage M; Human Genetics Center, School of Public Health and Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Suktitipat B; Department of Biochemistry, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand., Chen WM; Center for Public Health Genomics, University of Virginia, Charlottesville, VA 22908, USA., Li X; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Nutile T; Institute of Genetics and Biophysics 'A. Buzzati-Traverso,' Consiglio Nazionale delle Ricerche, Napoli 80131, Italy., Malerba G; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona 37134, Italy., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK., Bak T; Interdisciplinary Center Psychopathology and Emotion regulation, University Medical Center Groningen, University of Groningen, Groningen 9700 RB, the Netherlands., Schork N; Human Biology, J. Craig Venter Institute, La Jolla, CA 92037, USA; Quantitative Medicine, Translational Genomics Research Institute, Phoenix, AZ 85004, USA., Del Greco M F; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano 39100, Italy., Thiering E; Institute of Epidemiology, Helmholtz Zentrum München - German Research Centre for Environmental Health, Neuherberg 85764, Germany; Ludwig Maximilian University of Munich, Dr. von Hauner Children's Hospital, Munich 80337, Germany., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Marioni RE; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh EH8 9JZ, UK; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK., Mihailov E; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu 51010, Estonia., Eriksson J; Department of Internal Medicine and Clinical Nutrition, University of Gothenburg, Gothenburg 41345, Sweden., Ozel AB; Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109-5618, USA., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK; Department of Cardiology, Ealing Hospital, Middlesex UB1 3HW, UK., Nethander M; Bioinformatics Core Facility, Sahlgrenska Academy, University of Gothenburg, Gothenburg 413 90, Sweden., Cheng YC; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Aslibekyan S; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294-0022, USA., Ang W; Medical School, University of Western Australia, Perth, WA 6009, Australia., Gandin I; AREA Science Park, Trieste 34149, Italy., Yengo L; Centre National de la Recherche Scientifique UMR 8199, University of Lille, Institut Pasteur de Lille, European Genomic Institute for Diabetes, FR 3508, 59000 Lille, France; Program in Complex Trait Genomics, Institute for Molecular Bioscience, University of Queensland, St. Lucia, Brisbane, QLD 4072, Australia., Portas L; Support OU, Institute of Genetic and Biomedic Research, Consiglio Nazionale delle Ricerche, Sassari 7100, Italy., Kooperberg C; Fred Hutchinson Cancer Research Center, Public Health Sciences Division, Mail Stop M3-A410, 1100 Fairview Ave. N., Seattle, WA, USA., Hofer E; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University Graz, Graz 8036, Austria; Institute of Medical Informatics, Statistics and Documentation, Medical University Graz, Graz 8036, Austria., Rajan KB; Department of Internal Medicine, Rush University Medical Center, Chicago, IL 60612, USA., Schurmann C; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., den Hollander W; Department of Medical Statistics and Bio-informatics, Section Molecular Epidemiology, Leiden University Medical Center, Leiden 2333 ZC, the Netherlands., Ahluwalia TS; Steno Diabetes Center Copenhagen, Gentofte 2820, Denmark; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2100, Denmark., Zhao J; Center for Integrative Genomics, School of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA., Draisma HHM; Department of Biological Psychology, Netherlands Twin Register, Vrije Universiteit, Amsterdam 1081 BT, the Netherlands; Amsterdam Public Health research institute, VU University Medical Center, Amsterdam 1081 BT, the Netherlands; Neuroscience Campus Amsterdam, Amsterdam 1081 HV, the Netherlands., Ford I; Robertson Centre for Biostatistics, University of Glasgow, Glasgow G12 8QQ, UK., Timpson N; MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol BS8 2BN, UK., Teumer A; Department SHIP-KEF, Institute for Community Medicine, University Medicine Greifswald, Greifswald 17475, Germany., Huang H; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Wahl S; Institute of Epidemiology II, Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; German Center for Diabetes Research, Partner Site Munich, Munich 85764, Germany., Liu Y; Department of Epidemiology and Prevention, Public Health Sciences, Wake Forest University Health Sciences, Winston-Salem, NC 27157, USA., Huang J; Boston VA Research Institute, Inc., Boston, MA 02130, USA., Uh HW; Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden 2333 ZC, the Netherlands., Geller F; Department of Epidemiology Research, Statens Serum Institut, Copenhagen 2300, Denmark., Joshi PK; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH16 4UX, UK., Yanek LR; GeneSTAR Research Center, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Trabetti E; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona 37134, Italy., Lehne B; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK., Vozzi D; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo,' Trieste 34140, Italy., Verbanck M; Centre National de la Recherche Scientifique UMR 8199, University of Lille, Institut Pasteur de Lille, European Genomic Institute for Diabetes, FR 3508, 59000 Lille, France., Biino G; Institute of Molecular Genetics, Consiglio Nazionale delle Ricerche, Pavia 27100, Italy., Saba Y; Gottfried Schatz Research Center, Institute for Molecular Biology and Biochemistry, 8010 Graz, Austria., Meulenbelt I; Department of Medical Statistics and Bio-informatics, Section Molecular Epidemiology, Leiden University Medical Center, Leiden 2333 ZC, the Netherlands., O'Connell JR; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio 70210, Finland., Giulianini F; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA., Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden., Ballantyne CM; Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA; Methodist DeBakey Heart and Vascular Center, Houston, TX 77030, USA., Hottenga JJ; Department of Biological Psychology, Netherlands Twin Register, Vrije Universiteit, Amsterdam 1081 BT, the Netherlands., Montgomery GW; QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia., Rivadineira F; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam 3015 CN, the Netherlands., Rueedi R; Department of Computational Biology, University of Lausanne, Lausanne 1010, Switzerland; Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland., Steri M; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche, Sardinia 08045, Italy., Herzig KH; Department of Physiology, Institute of Biomedicine, University of Oulu, Medical Research Center Oulu and Oulu University Hospital, Oulu 90014, Finland; Biocenter Oulu, University of Oulu, Oulu 90220, Finland; Department of Gastroenterology and Metabolism, Poznan University of Medical Sciences, Poznan 60-512, Poland., Stott DJ; Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow G12 8QQ, UK., Menni C; Department of Twin Research & Genetic Epidemiology, King's College London, London SE1 7EH, UK., Frånberg M; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, Stockholm 17176, Sweden; Department of Numerical Analysis and Computer Science, Stockholm University, Stockholm 100 44, Sweden., St Pourcain B; MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol BS8 2BN, UK; Donders Institute, Radboud University, Nijmegen 6525 XD, the Netherlands., Felix SB; German Centre for Cardiovascular Research, Partner Site Greifswald, Greifswald 17475, Germany; Department for Internal Medicine B, University Medicine Greifswald, Greifswald 17475, Germany., Pers TH; Department of Epidemiology Research, Statens Serum Institut, Copenhagen 2300, Denmark; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2100, Denmark., Bakker SJL; Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen 9713 GZ, the Netherlands., Kraft P; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA., Peters A; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherber 85764, Germany., Vaidya D; GeneSTAR Research Center, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Delgado G; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim 68167, Germany., Smit JH; Department of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, Amsterdam University Medical Center/GGZ inGeest Research & Innovation, Amsterdam 1081 HJ, the Netherlands., Großmann V; Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University Mainz, Mainz 55131, Germany., Sinisalo J; Heart and Lung Center, Helsinki University Hospital and Helsinki University, Helsinki 00029, Finland., Seppälä I; Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33014, Finland; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere 33520, Finland., Williams SR; Department of Neurology, University of Virginia, Charlottesville, VA 22908, USA., Holliday EG; Hunter Medical Research Institute, New Lambon Heights, NSW 2305, Australia; Centre for Clinical Epidemiology & Biostatistics, Faculty of Health and Medicine, University of Newcastle, Callaghan, NSW 2308, Australia., Moed M; Molecular Epidemiology, Leiden University Medical Center, Leiden 2333 ZC, the Netherlands., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK., Räikkönen K; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki 00014, Finland., Ding J; Department of Internal Medicine/Geriatrics, Wake Forest University Health Sciences, Winston-Salem, NC 27157, USA., Campbell H; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH16 4UX, UK., Sale MM; Center for Public Health Genomics, University of Virginia, Charlottesville, VA 22908, USA., Chen YI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., James AL; Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia; Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia., Ruggiero D; Institute of Genetics and Biophysics 'A. Buzzati-Traverso,' Consiglio Nazionale delle Ricerche, Napoli 80131, Italy; IRCCS Neuromed, Pozzilli (IS) 86077, Italy., Soranzo N; Sanger Institute, Wellcome Trust Genome Campus, Hinxton CB10 1SA, UK., Hartman CA; Interdisciplinary Center Psychopathology and Emotion regulation, University Medical Center Groningen, University of Groningen, Groningen 9700 RB, the Netherlands., Smith EN; Department of Pediatrics and Rady Children's Hospital, School of Medicine, University of California, San Diego, La Jolla, CA 92037, USA., Berenson GS; Center for Cardiovascular Health, Tulane University, New Orleans, LA 70112, USA., Fuchsberger C; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano 39100, Italy., Hernandez D; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD 20892, USA., Tiesler CMT; Institute of Epidemiology, Helmholtz Zentrum München - German Research Centre for Environmental Health, Neuherberg 85764, Germany; Ludwig Maximilian University of Munich, Dr. von Hauner Children's Hospital, Munich 80337, Germany., Giedraitis V; Department of Public Health and Caring Sciences, Molecular Geriatrics, Uppsala University, Uppsala 752 37, Sweden., Liewald D; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh EH8 9JZ, UK., Fischer K; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu 51010, Estonia., Mellström D; Department of Internal Medicine and Clinical Nutrition, University of Gothenburg, Gothenburg 41345, Sweden., Larsson A; Department of Medical Sciences, Uppsala University, Uppsala 751 41, Sweden., Wang Y; Department of Medicine, Case Cardiovascular Research Institute, Case Western Reserve University, Harrington Heart & Vascular Institute, University Hospitals, Cleveland, OH 44106, USA., Scott WR; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK., Lorentzon M; Department of Internal Medicine and Clinical Nutrition, University of Gothenburg, Gothenburg 41345, Sweden; Geriatric Medicine, Sahlgrenska University Hospital, Mölndal 431 80, Sweden., Beilby J; PathWest Laboratory Medicine WA, Nedlands, WA 6009, Australia; School of Biomedical Sciences, University of Western Australia, Crawley, Perth, WA 6009, Australia., Ryan KA; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Pennell CE; Medical School, University of Western Australia, Perth, WA 6009, Australia., Vuckovic D; Medical Sciences, Surgical and Health Department, University of Trieste, Trieste 34137, Italy., Balkau B; INSERM U1018, Centre de Recherche en Epidémiologie et Santé des Populations, Team 5 (EpReC, Renal, and Cardiovascular Epidemiology), Université de Versailles Saint-Quentin-en-Yvelines, Université Paris-Saclay, Villejuif 94807, France., Concas MP; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo,' Trieste 34140, Italy., Schmidt R; Clinical Division of Neurogeriatrics, Department of Neurology, Medical University Graz, Graz 8036, Austria., Mendes de Leon CF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI 48109, USA., Bottinger EP; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Kloppenburg M; Department of Rheumatology, Leiden University Medical Center, Leiden 2300 RC, the Netherlands; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden 2333 ZC, the Netherlands., Paternoster L; MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol BS8 2BN, UK., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Musk AW; Busselton Population Medical Research Institute, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia; Department of Respiratory Medicine, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia., Willemsen G; Department of Biological Psychology, Netherlands Twin Register, Vrije Universiteit, Amsterdam 1081 BT, the Netherlands., Evans DM; University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, QLD 4102, Australia; MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol BS8 2BN, UK., Madden PAF; Department of Psychiatry, Washington University School of Medicine, 4560 Clayton Ave., Suite 1000, St. Louis, MO 63110, USA., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere 33520, Finland; Department of Clinical Physiology, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere 33520, Finland., Kutalik Z; Swiss Institute of Bioinformatics, Lausanne 1015, Switzerland; Institute of Social and Preventive Medicine, University Hospital of Lausanne, Lausanne 1010, Switzerland., Zoledziewska M; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche, Sardinia 08045, Italy., Karhunen V; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, 90014 Oulun yliopisto, Finland., Kritchevsky SB; Gerontology and Geriatric Medicine, Sticht Center on Aging and Rehabilitation, Wake Forest University Health Sciences, Winston-Salem, NC 27157, USA., Sattar N; BHF Glasgow Cardiovascular Research Centre, Faculty of Medicine, Glasgow G12 8TA, UK., Lachance G; Department of Twin Research & Genetic Epidemiology, King's College London, London SE1 7EH, UK., Clarke R; Clinical Trial Service Unit, Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, National Institutes of Health, Bethesda, MD 20892, USA., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku 20520, Finland; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku 20520, Finland., Attia JR; Hunter Medical Research Institute, New Lambon Heights, NSW 2305, Australia; Centre for Clinical Epidemiology & Biostatistics, Faculty of Health and Medicine, University of Newcastle, Callaghan, NSW 2308, Australia; John Hunter Hospital, New Lambton Heights, NWS 2305, Australia., van Heemst D; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden 2333 ZA, the Netherlands., Kajantie E; Chronic Disease Prevention Unit, National Institute for Health and Welfare, Helsinki 00014, Finland; Hospital for Children and Adolescents, Helsinki University Central Hospital and University of Helsinki, Helsinki 00290, Finland; Department of Obstetrics and Gynaecology, MRC Oulu, Oulu University Hospital and University of Oulu, Oulu 90014, Finland., Sorice R; Institute of Genetics and Biophysics 'A. Buzzati-Traverso,' Consiglio Nazionale delle Ricerche, Napoli 80131, Italy., Gambaro G; Division of Nephrology and Dialysis, Columbus-Gemelli University Hospital, Università Cattolica del Sacro Cuore, Roma 168, Italy., Scott RA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK., Hicks AA; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano 39100, Italy., Ferrucci L; Translational Gerontology Branch, National Institute on Aging, Baltimore, MD 21224, USA., Standl M; Institute of Epidemiology, Helmholtz Zentrum München - German Research Centre for Environmental Health, Neuherberg 85764, Germany., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7FZ, UK; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA 02142, USA., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh EH8 9JZ, UK; Alzheimer's Scotland Dementia Research Centre, University of Edinburgh, Edinburgh EH8 9JZ, UK., Karlsson M; Department of Clinical Sciences and Orthopaedic Surgery, Lund University, Malmo 20502, Sweden., Lind L; Department of Medical Sciences, Uppsala University, Uppsala 751 41, Sweden., Li JZ; Department of Human Genetics, University of Michigan, Ann Arbor, MI 48109-5618, USA., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK; Department of Cardiology, Ealing Hospital, Middlesex UB1 3HW, UK; Imperial College Healthcare NHS Trust, London W12 0HS, UK; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 308232, Singapore; MRC-PHE Centre for Environment and Health, Imperial College London, London W2 1PG, UK., Mori TA; Medical School, University of Western Australia, Perth, WA 6009, Australia., de Geus EJCN; Department of Biological Psychology, Netherlands Twin Register, Vrije Universiteit, Amsterdam 1081 BT, the Netherlands; Amsterdam Public Health research institute, VU University Medical Center, Amsterdam 1081 BT, the Netherlands., Heath AC; Department of Psychiatry, Washington University School of Medicine, 4560 Clayton Ave., Suite 1000, St. Louis, MO 63110, USA., Martin NG; QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia., Auvinen J; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, 90014 Oulun yliopisto, Finland; Unit of Primary Health Care, Oulu University Hospital, Oulu 90220, Finland., Buckley BM; Department of Epidemiology and Public Health, University College Cork, Cork T12 K8AF, Ireland., de Craen AJM; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden 2333 ZA, the Netherlands., Waldenberger M; Institute of Epidemiology II, Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; German Center for Cardiovascular Research, Partner Site Munich Heart Alliance, 80636 Munich, Germany., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; Genetic Epidemiology, Institute of Medical Informatics, Biometry, and Epidemiology, Faculty of Medicine, Ludwig Maximilian University of Munich, Neuherberg 85764, Germany., Meitinger T; Institute of Human Genetics, Technische Universität München, Munich 85764, Germany; Institute of Human Genetics, Helmholtz Zentrum München, Neuherberg 85764, Germany; Munich Cluster for Systems Neurology (SyNergy), Munich 81377, Germany., Scott RJ; Hunter Medical Research Institute, New Lambon Heights, NSW 2305, Australia; Information-Based Medicine Stream, Hunter Medical Research Institute, New Lambton Heights, NSW 2305, Australia., McEvoy M; Hunter Medical Research Institute, New Lambon Heights, NSW 2305, Australia; Centre for Clinical Epidemiology & Biostatistics, Faculty of Health and Medicine, University of Newcastle, Callaghan, NSW 2308, Australia., Beekman M; Molecular Epidemiology, Leiden University Medical Center, Leiden 2333 ZC, the Netherlands., Bombieri C; Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona 37134, Italy., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC 27599, USA., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden., Morrison AC; Human Genetics Center, Department of Epidemiology, Human Genetics, and Environmental Sciences, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Boomsma DI; Department of Biological Psychology, Netherlands Twin Register, Vrije Universiteit, Amsterdam 1081 BT, the Netherlands., Whitfield JB; QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia., Strachan DP; Population Health Research Institute, St. George's, University of London, London SW17 0RE, UK., Hofman A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CA, the Netherlands., Vollenweider P; Department of Internal Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne 1011, Switzerland., Cucca F; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche, Sardinia 08045, Italy., Jarvelin MR; Biocenter Oulu, University of Oulu, Oulu 90220, Finland; Center for Life Course Health Research, Faculty of Medicine, University of Oulu, 90014 Oulun yliopisto, Finland; Unit of Primary Health Care, Oulu University Hospital, Oulu 90220, Finland; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London W2 1PG, UK; Department of Life Sciences, College of Health and Life Sciences, Brunel University London, Kingston Lane, Uxbridge, Middlesex UB8 3PH, UK., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden 2300 RC, the Netherlands; Durrer Center for Cardiogenetic Research, Amsterdam 3501 DG, the Netherlands; Interuniversity Cardiology Institute of the Netherlands, Utrecht 3511 EP, the Netherlands., Spector TD; Department of Twin Research & Genetic Epidemiology, King's College London, London SE1 7EH, UK., Hamsten A; Cardiovascular Medicine Unit, Department of Medicine, Center for Molecular Medicine, Karolinska Institutet, Stockholm 17176, Sweden., Zeller T; Department of General and Interventional Cardiology, University Heart Center Hamburg, Hamburg 20246, Germany; German Center for Cardiovascular Research, Partner Site RhineMain, 55131 Mainz, Germany., Uitterlinden AG; Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CA, the Netherlands; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam 3015 CN, the Netherlands., Nauck M; German Centre for Cardiovascular Research, Partner Site Greifswald, Greifswald 17475, Germany; Institute for Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald 17475, Germany., Gudnason V; Icelandic Heart Association, Kopavogur 201, Iceland; Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland., Qi L; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA., Grallert H; Institute of Epidemiology II, Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; German Center for Diabetes Research, Partner Site Munich, Munich 85764, Germany., Borecki IB; Analytical Genetics Group, Regeneron Genetics Center, Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591, USA., Rotter JI; Institute for Translational Genomics and Population Sciences, Departments of Pediatrics and Medicine, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., März W; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim 68167, Germany; Synlab Academy, Synlab Holding Deutschland GmbH, Mannheim 68161, Germany; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz 8036, Austria., Wild PS; German Center for Cardiovascular Research, Partner Site RhineMain, 55131 Mainz, Germany; Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University Mainz, Mainz 55131, Germany; Preventive Cardiology and Preventive Medicine, Center for Cardiology, University Medical Center of the Johannes Gutenberg-University Mainz, Mainz 55131, Germany., Lokki ML; Transplantation Laboratory, Medicum, University of Helsinki, Helsinki 00014, Finland., Boyle M; John Hunter Hospital, New Lambton Heights, NWS 2305, Australia., Salomaa V; National Institute for Health and Welfare, Helsinki 00271, Finland., Melbye M; Department of Epidemiology Research, Statens Serum Institut, Copenhagen 2300, Denmark; Department of Clinical Medicine, University of Copenhagen, Copenhagen 2300, Denmark; Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA., Eriksson JG; National Institute for Health and Welfare, Helsinki 00271, Finland; Folkhälsan Research Centre, Helsinki 00250, Finland; Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki 00014, Finland., Wilson JF; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH16 4UX, UK; MRC Human Genetics Unit, Institute for Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK., Penninx BWJH; Department of Psychiatry, Amsterdam Neuroscience and Amsterdam Public Health Research Institute, Amsterdam University Medical Center/GGZ inGeest Research & Innovation, Amsterdam 1081 HJ, the Netherlands., Becker DM; GeneSTAR Research Center, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Worrall BB; Departments of Neurology and Public Health Sciences, University of Virginia Charlottesville, Charlottesville, VA 22908-0394, USA., Gibson G; Center for Integrative Genomics, School of Biology, Georgia Institute of Technology, Atlanta, GA 30332, USA., Krauss RM; Children's Hospital Oakland Research Institute, Oakland, CA 94609, USA., Ciullo M; Institute of Genetics and Biophysics 'A. Buzzati-Traverso,' Consiglio Nazionale delle Ricerche, Napoli 80131, Italy; IRCCS Neuromed, Pozzilli (IS) 86077, Italy., Zaza G; Renal Unit, Department of Medicine, Verona University Hospital, Verona 37126, Italy., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge CB2 0QQ, UK., Oldehinkel AJ; Interdisciplinary Center Psychopathology and Emotion regulation, University Medical Center Groningen, University of Groningen, Groningen 9700 RB, the Netherlands., Palmer LJ; School of Public Health, University of Adelaide, Adelaide, SA 5000, Australia., Murray SS; Department of Pathology, University of California, San Diego, San Diego, CA 92121, USA., Pramstaller PP; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lübeck, Bolzano 39100, Italy; General Central Hospital, Department of Neurology, Bolzano 39100, Italy; Department of Neurology, University of Lübeck, Lübeck 23538, Germany., Bandinelli S; Geriatric Unit, Azienda Sanitaria Firenze, Florence 50122, Italy., Heinrich J; Institute of Epidemiology, Helmholtz Zentrum München - German Research Centre for Environmental Health, Neuherberg 85764, Germany; Institute and Clinic for Occupational, Social and Environmental Medicine, University Hospital, LMU Munich, Comprehensive Pneumology Center Munich, Member DZL, German Center for Lung Research, 81377 Munich, Germany., Ingelsson E; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala 751 41, Sweden; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Stanford Cardiovascular Institute, Stanford University, Stanford, CA 94305, USA., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh EH8 9JZ, UK; Department of Psychology, University of Edinburgh, Edinburgh EH8 9JZ, UK., Mägi R; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu 51010, Estonia., Vandenput L; Department of Internal Medicine and Clinical Nutrition, University of Gothenburg, Gothenburg 41345, Sweden., van der Harst P; University of Groningen, University Medical Center Groningen, Department of Cardiology, Groningen 9713 AV, the Netherlands., Desch KC; Department of Pediatrics and Communicable Diseases, University of Michigan, Ann Arbor, MI 48109, USA., Kooner JS; Department of Cardiology, Ealing Hospital, Middlesex UB1 3HW, UK; Imperial College Healthcare NHS Trust, London W12 0HS, UK; MRC-PHE Centre for Environment and Health, Imperial College London, London W2 1PG, UK; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK., Ohlsson C; Department of Internal Medicine and Clinical Nutrition, University of Gothenburg, Gothenburg 41345, Sweden., Hayward C; MRC Human Genetics Unit, Institute for Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, UK., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33014, Finland; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere 33520, Finland., Shuldiner AR; Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Arnett DK; University of Kentucky, College of Public Health, Lexington, KY 40508, USA., Beilin LJ; Medical School, University of Western Australia, Perth, WA 6009, Australia., Robino A; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo,' Trieste 34140, Italy., Froguel P; Centre National de la Recherche Scientifique UMR 8199, University of Lille, Institut Pasteur de Lille, European Genomic Institute for Diabetes, FR 3508, 59000 Lille, France; Department of Genomics of Common Disease, School of Public Health, Imperial College London, London SW7 2AZ, UK., Pirastu M; Support OU, Institute of Genetic and Biomedic Research, Consiglio Nazionale delle Ricerche, Sassari 7100, Italy., Jess T; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Frederiksberg 2200, Denmark., Koenig W; German Center for Cardiovascular Research, Partner Site Munich Heart Alliance, 80636 Munich, Germany; Department of Internal Medicine II-Cardiology, University of Ulm Medical Center, 80801 Ulm, Germany; Deutsches Herzzentrum München, Technische Universität München, 80636 Munich, Germany., Loos RJF; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA; Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029-6542, USA., Evans DA; Department of Internal Medicine, Rush University Medical Center, Chicago, IL 60612, USA., Schmidt H; Department of Neurology, Medical University Graz, Graz 8010, Austria; Institute of Molecular Biology and Biochemistry, Centre for Molecular Medicine, Medical University of Graz, Graz 8010, Austria., Smith GD; MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Bristol BS8 2BN, UK., Slagboom PE; Molecular Epidemiology, Leiden University Medical Center, Leiden 2333 ZC, the Netherlands., Eiriksdottir G; Icelandic Heart Association, Kopavogur 201, Iceland., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK; Department of Biostatistics, University of Liverpool, Liverpool L69 3GL, UK., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98101, USA; Department of Epidemiology, University of Washington, Seattle, WA 98101, USA; Department of Health Services, University of Washington, Seattle, WA 98195-7660, USA; Kaiser Permanente Washington Health Research Institute, Seattle, WA 98101, USA., Tracy RP; Department of Pathology, University of Vermont, Colchester, VT 05405, USA., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands., Boerwinkle E; Human Genetics Center, School of Public Health, University of Texas Health Science Center at Houston, Houston, TX 77030, USA; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX 77030, USA., Visvikis-Siest S; Université de Lorraine, INSERM, IGE-PCV, 54000 Nancy, France., Reiner AP; Department of Epidemiology, University of Washington, Seattle, WA 98101, USA., Gross M; Department of Lab Medicine and Pathology, University of Minnesota, Minneapolis, MN 55455, USA., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA 98101, USA., Franke L; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands., Franco OH; Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CA, the Netherlands; Institute of Social and Preventive Medicine, University of Bern, 3012 Bern, Switzerland., Benjamin EJ; Department of Medicine, Boston University School of Medicine, Boston, MA 02118, USA; National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA 01702, USA., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA; Harvard Medical School, Boston, MA 02115, USA., Dupuis J; National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, MA 01702, USA; Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands., Dehghan A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam 3000 CA, the Netherlands; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment & Health, School of Public Health, Imperial College London, London W2 1PG, UK. Electronic address: a.dehghan@imperial.ac.uk., Alizadeh BZ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands. Electronic address: b.z.alizadeh@umcg.nl.
Publikováno v:
American journal of human genetics [Am J Hum Genet] 2018 Nov 01; Vol. 103 (5), pp. 691-706.
Autor:
Sung YJ; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address: yunju@wustl.edu., Winkler TW; Department of Genetic Epidemiology, University of Regensburg, Regensburg 93051, Germany., de Las Fuentes L; Cardiovascular Division, Department of Medicine, Washington University, St. Louis, MO 63110, USA., Bentley AR; Center for Research on Genomics and Global Health, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA., Brown MR; Department of Epidemiology, Human Genetics, and Environmental Sciences, The University of Texas School of Public Health, Houston, TX 77030, USA., Kraja AT; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO 63108, USA., Schwander K; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO 63110, USA., Ntalla I; William Harvey Research Institute, Clinical Pharmacology, Queen Mary University of London, London EC1M 6BQ, UK., Guo X; Genomic Outcomes, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Franceschini N; Department of Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC 27514, USA., Lu Y; Icahn School of Medicine at Mount Sinai, The Charles Bronfman Institute for Personalized Medicine, New York, NY 10029, USA., Cheng CY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore 169856, Singapore; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore 169857, Singapore; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore 117597, Singapore., Sim X; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore 117549, Singapore., Vojinovic D; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Marten J; Medical Research Council Human Genetics Unit, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK., Musani SK; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39213, USA., Li C; Department of Epidemiology and Biostatistics, University of Giorgia at Athens College of Public Health, Athens, GA 30602, USA., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO 63108, USA., Kilpeläinen TO; Section of Metabolic Genetics, Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2100, Denmark; Department of Environmental Medicine and Public Health, The Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Richard MA; Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Noordam R; Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden 2300RC, the Netherlands., Aslibekyan S; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Aschard H; Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA; Centre de Bioinformatique Biostatistique et Biologie Integrative (C3BI), Institut Pasteur, Paris 75015, France., Bartz TM; Cardiovascular Health Research Unit, Biostatistics and Medicine, University of Washington, Seattle, WA 98101, USA., Dorajoo R; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore 138672, Singapore., Liu Y; Division of Biostatistical Sciences, Department of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA., Manning AK; Center for Human Genetics Research, Massachusetts General Hospital, Boston, MA 02114, USA; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Rankinen T; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA., Smith AV; Icelandic Heart Association, Kopavogur 201, Iceland; Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland., Tajuddin SM; Health Disparities Research Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, NIH, Baltimore, MD 21224, USA., Tayo BO; Department of Public Health Sciences, Loyola University Chicago, Maywood, IL 60153, USA., Warren HR; William Harvey Research Institute, Clinical Pharmacology, Queen Mary University of London, London EC1M 6BQ, UK; NIHR Cardiovascular Biomedical Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK., Zhao W; School of Public Health, Department of Epidemiology, University of Michigan, Ann Arbor, MI 48109, USA., Zhou Y; Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA., Matoba N; Laboratory for Statistical Analysis, Center for Integrative Medical Sciences, RIKEN, Yokohama 230-0045, Japan., Sofer T; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA., Alver M; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia., Amini M; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands., Boissel M; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille 59000, France., Chai JF; Saw Swee Hock School of Public Health, National University of Singapore, Singapore 117549, Singapore., Chen X; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden., Divers J; Division of Biostatistical Sciences, Department of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA., Gandin I; Department of Medical Sciences, University of Trieste, Trieste 34137, Italy., Gao C; Department of Molecular Genetics and Genomics Program, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA., Giulianini F; Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA., Goel A; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, Oxfordshire OX3 9DU, UK; Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Harris SE; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh EH8 9JZ, UK; Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine and MRC Institute of Genetics and Molecular Medicine, The University of Edinburgh, Edinburgh EH4 2XU, UK., Hartwig FP; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, RS 96020220, Brazil., Horimoto ARVR; Lab Genetics and Molecular Cardiology, Department of Cardiology, Heart Institute, University of Sao Paulo, Sao Paulo, Brazil., Hsu FC; Division of Biostatistical Sciences, Department of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Kähönen M; Department of Clinical Physiology, Faculty of Medicine and Life Sciences, University of Tampere, Tampere 33014, Finland; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland., Kasturiratne A; Department of Public Health, University of Kelaniya, Ragama, Sri Lanka., Kühnel B; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany., Leander K; Institute of Environmental Medicine, Karolinska Institutet, Stockholm 17177, Sweden., Lee WJ; Department of Medical Research, Taichung Veterans General Hospital, Department of Social Work, Tunghai University, Taichung 40705, Taiwan., Lin KH; Department of Opthalmology, Taichung Veterans General Hospital, Taichung 40705, Taiwan., 'an Luan J; MRC Epidemiology Unit, University of Cambridge, Cambridge CB2 0QQ, UK., McKenzie CA; Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona JMAAW15, Jamaica., Meian H; Department of Occupational and Environmental Health and State Key Laboratory of Environmental Health for Incubating, School of Public Health, Tongji Medical College Huazhong University of Science and Technology, Wuhan, China., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Leicester LE3 9QP, UK; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester LE3 9QP, UK., Rauramaa R; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio 70100, Finland., Schupf N; Taub Institute for Research on Alzheimer disease and the Aging Brain, Department of Epidemiology, Columbia University Mailman School of Public Health, New York, NY 10032, USA., Scott RA; MRC Epidemiology Unit, University of Cambridge, Cambridge CB2 0QQ, UK., Sheu WHH; Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung 40705, Taiwan; School of Medicine, National Yang-ming University, Taipei, Taiwan; School of Medicine, National Defense Medical Center, Taipei, Taiwan; Institute of Medical Technology, National Chung-Hsing University, Taichung 40705, Taiwan., Stančáková A; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio 70210, Finland., Takeuchi F; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo 1628655, Japan., van der Most PJ; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands., Varga TV; Genetic and Molecular Epidemiology Unit, Department of Clinical Sciences, Lund University, Malmö, Skåne 205 02, Sweden., Wang H; Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH 44106, USA., Wang Y; Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH 44106, USA., Ware EB; School of Public Health, Department of Epidemiology, University of Michigan, Ann Arbor, MI 48109, USA; Institute for Social Research, Research Center for Group Dynamics, University of Michigan, Ann Arbor, MI 48104, USA., Weiss S; Interfaculty Institute for Genetics and Functional Genomics, University Medicine and Ernst-Moritz Arndt University Greifswald, Greifswald 17487, Germany; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald 17475, Germany., Wen W; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37203, USA., Yanek LR; General Internal Medicine, GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK; Department of Cardiology, Ealing Hospital, Middlesex UB1 3HW, UK., Zhao JH; MRC Epidemiology Unit, University of Cambridge, Cambridge CB2 0QQ, UK., Afaq S; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK., Alfred T; Icahn School of Medicine at Mount Sinai, The Charles Bronfman Institute for Personalized Medicine, New York, NY 10029, USA., Amin N; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Arking D; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Aung T; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore 169856, Singapore; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore 169857, Singapore; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore 117597, Singapore., Barr RG; Departments of Medicine and Epidemiology, Columbia University Medical Center, New York, NY 10032, USA., Bielak LF; School of Public Health, Department of Epidemiology, University of Michigan, Ann Arbor, MI 48109, USA., Boerwinkle E; Human Genetics Center, The University of Texas School of Public Health, Houston, TX 77030, USA; Institute of Molecular Medicine, The University of Texas Health Science Center, Houston, TX 77030, USA., Bottinger EP; Icahn School of Medicine at Mount Sinai, The Charles Bronfman Institute for Personalized Medicine, New York, NY 10029, USA., Braund PS; Department of Cardiovascular Sciences, University of Leicester, Leicester LE3 9QP, UK; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester LE3 9QP, UK., Brody JA; Cardiovascular Health Research Unit, Medicine, University of Washington, Seattle, WA 98101, USA., Broeckel U; Section of Genomic Pediatrics, Department of Pediatrics, Medicine and Physiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA., Cabrera CP; William Harvey Research Institute, Clinical Pharmacology, Queen Mary University of London, London EC1M 6BQ, UK; NIHR Cardiovascular Biomedical Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK., Cade B; Sleep Medicine and Circadian Disorders, Brigham and Women's Hospital, Boston, MA 02115, USA., Caizheng Y; Department of Occupational and Environmental Health and State Key Laboratory of Environmental Health for Incubating, School of Public Health, Tongji Medical College Huazhong University of Science and Technology, Wuhan, China., Campbell A; Centre for Genomic & Experimental Medicine, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK., Canouil M; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille 59000, France., Chakravarti A; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA., Chauhan G; Centre for Brain Research, Indian Institute of Schience, Bangalore 560012, India., Christensen K; The Danish Aging Research Center, Institute of Public Health, University of Southern Denmark, Odense, Denmark., Cocca M; Department of Medical Sciences, University of Trieste, Trieste 34137, Italy., Collins FS; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA., Connell JM; Ninewells Hospital & Medical School, University of Dundee, Dundee DD1 9SY, UK., de Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden 2300RC, the Netherlands., de Silva HJ; Department of Medicine, University of Kelaniya, Ragama, Sri Lanka., Debette S; Inserm U1219 Neuroepidemiology, University of Bordeaux, Bordeaux, France; Department of Neurology, University Hospital, Bordeaux, France; Boston University School of Medicine, Boston, MA 02118, USA., Dörr M; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald 17475, Germany; Department of Internal Medicine B, University Medicine Greifswald, Greifswald 17475, Germany., Duan Q; Department of Genetics, University of North Carolina, Chapel Hill, NC 27514, USA., Eaton CB; Department of Family Medicine and Epidemiology, Alpert Medical School of Brown University, Providence, RI 02860, USA., Ehret G; Center for Complex Disease Genomics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA; Division of Cardiology, Department of Specialties of Medicine, Geneva University Hospital, Geneva 1211, Switzerland., Evangelou E; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina 45110, Greece., Faul JD; Institute for Social Research, Survey Research Center, University of Michigan, Ann Arbor, MI 48104, USA., Fisher VA; Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA., Forouhi NG; MRC Epidemiology Unit, University of Cambridge, Cambridge CB2 0QQ, UK., Franco OH; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Friedlander Y; Braun School of Public Health, Hebrew University-Hadassah Medical Center, Jerusalem 91120, Israel., Gao H; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK; MRC-PHE Centre for Environment and Health, Department of Epidemiology & Biostatistics, School of Public Health, Imperial College London, London, UK., Gigante B; Institute of Environmental Medicine, Karolinska Institutet, Stockholm 17177, Sweden., Graff M; Department of Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC 27514, USA., Gu CC; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO 63110, USA., Gu D; Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China., Gupta P; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore 169856, Singapore., Hagenaars SP; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh EH8 9JZ, UK; Department of Psychology, The University of Edinburgh, Edinburgh EH8 9JZ, UK., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, NIH, Bethesda, MD 20892, USA., He J; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA; Department of Medicine, Tulane University School of Medicine, New Orleans, LA 70112, USA., Heikkinen S; University of Eastern Finland, Institute of Biomedicine, Kuopio 70211, Finland., Heng CK; Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore; Khoo Teck Puat - National University Children's Medical Institute, National University Health System, Singapore 119228, Singapore., Hirata M; Laboratory of Genome Technology, Human Genome Center, Institute of Medical Science, The University of Tokyo, Minato-ku 108-8639, Japan., Hofman A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Howard BV; MedStar Health Research Institute, Hyattsville, MD 20782, USA; Center for Clinical and Translational Sciences and Department of Medicine, Georgetown-Howard Universities, Washington, DC 20057, USA., Hunt S; Cardiovascular Genetics, Department of Internal Medicine, University of Utah, Salt Lake City, UT 84108, USA; Weill Cornell Medicine in Qatar, Doha, Qatar., Irvin MR; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA., Jia Y; Genomic Outcomes, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Joehanes R; Hebrew SeniorLife, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02131, USA; Framingham Heart Study, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20982, USA., Justice AE; Department of Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC 27514, USA., Katsuya T; Department of Clinical Gene Therapy, Osaka University Graduate School of Medicine, Suita 5650871, Japan; Department of Geriatric and General Medicine, Osaka University Graduate School of Medicine, Suita 5650871, Japan., Kaufman J; Epidemiology, Department of Occupational and Environmental Medicine Program, University of Washington, Seattle, WA 98105, USA., Kerrison ND; MRC Epidemiology Unit, University of Cambridge, Cambridge CB2 0QQ, UK., Khor CC; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore 138672, Singapore; Department of Biochemistry, National University of Singapore, Singapore 117596, Singapore., Koh WP; Saw Swee Hock School of Public Health, National University of Singapore, Singapore 117549, Singapore; Duke-NUS Medical School, Singapore 169857, Singapore., Koistinen HA; Department of Health, National Institute for Health and Welfare, Helsinki 00271, Finland; Department of Medicine and Abdominal Center: Endocrinology, University of Helsinki and Helsinki University Central Hospital, Helsinki 00029, Finland., Komulainen P; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio 70100, Finland., Kooperberg C; Fred Hutchinson Cancer Research Center, University of Washington School of Public Health, Seattle, WA 98109, USA., Krieger JE; Lab Genetics and Molecular Cardiology, Department of Cardiology, Heart Institute, University of Sao Paulo, Sao Paulo, Brazil., Kubo M; Center for Integrative Medical Sciences, RIKEN, Yokohama 230-0045, Japan., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio 70210, Finland., Langefeld CD; Division of Biostatistical Sciences, Department of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA., Langenberg C; MRC Epidemiology Unit, University of Cambridge, Cambridge CB2 0QQ, UK., Launer LJ; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, NIH, Bethesda, MD 20892, USA., Lehne B; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK., Lewis CE; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35205, USA., Li Y; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO 63110, USA., Lim SH; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore 169856, Singapore., Lin S; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO 63108, USA., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA., Liu J; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore 117549, Singapore; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore 138672, Singapore., Liu J; WHI CCC, Fred Hutchinson Cancer Research Center, Seattle, WA 98115, USA., Liu K; Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Liu Y; Genomic Outcomes, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Loh M; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research 138648, Singapore., Lohman KK; Division of Biostatistical Sciences, Department of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA., Long J; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37203, USA., Louie T; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA., Mägi R; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia., Mahajan A; Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Meitinger T; Institute of Human Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; Institute of Human Genetics, Technische Universität München, Munich 80333, Germany., Metspalu A; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia., Milani L; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia., Momozawa Y; Laboratory for Genotyping Development, Center for Integrative Medical Sciences, RIKEN, Yokohama 230-0045, Japan., Morris AP; Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK; Department of Biostatistics, University of Liverpool, Liverpool L69 3GL, UK., Mosley TH Jr; Geriatrics, Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA., Munson P; Mathematical and Statistical Computing Laboratory, Center for Information Technology, NIH, Bethesda, MD 20892, USA., Murray AD; The Institute of Medical Sciences, Aberdeen Biomedical Imaging Centre, University of Aberdeen, Aberdeen AB25 2ZD, UK., Nalls MA; Data Tecnica International, Glen Echo, MD 20812, USA; Laboratory of Neurogenetics, National Institute on Aging, Bethesda, MD 20892, USA., Nasri U; Genomic Outcomes, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Norris JM; Department of Epidemiology, Colorado School of Public Health, Aurora, CO 80045, USA., North K; Department of Epidemiology, University of North Carolina Gillings School of Global Public Health, Chapel Hill, NC 27514, USA., Ogunniyi A; Department of Medicine, University of Ibadan, Ibadan, Nigeria., Padmanabhan S; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8TA, UK., Palmas WR; Internal Medicine, Department of Medicine, Columbia University, New York, NY 10032, USA., Palmer ND; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA., Pankow JS; Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, MN 55454, USA., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden., Peters A; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Neuherberg 85764, Germany., Peyser PA; School of Public Health, Department of Epidemiology, University of Michigan, Ann Arbor, MI 48109, USA., Polasek O; Faculty of Medicine, University of Split, Split, Croatia., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku 20521, Finland; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku 20520, Finland., Renström F; Genetic and Molecular Epidemiology Unit, Department of Clinical Sciences, Lund University, Malmö, Skåne 205 02, Sweden; Department of Biobank Research, Umeå University, Umeå, Västerbotten 901 87, Sweden., Rice TK; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO 63110, USA., Ridker PM; Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA., Robino A; Medical Genetics, IRCCS Burlo, Garofolo 34137, Italy., Robinson JG; Department of Epidemiology and Medicine, University of Iowa, Iowa City, IA 52242, USA., Rose LM; Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA., Rudan I; Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh EH8 9AG, UK., Sabanayagam C; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore 169856, Singapore; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore 169857, Singapore., Salako BL; Department of Medicine, University of Ibadan, Ibadan, Nigeria., Sandow K; Genomic Outcomes, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Schmidt CO; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald 17475, Germany; Institute for Community Medicine, University Medicine Greifswald, Greifswald 17475, Germany., Schreiner PJ; Division of Epidemiology and Community Health, University of Minnesota School of Public Health, Minneapolis, MN 55454, USA., Scott WR; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK., Seshadri S; Framingham Heart Study, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20982, USA; Department of Neurology, Boston University School of Medicine, Boston, MA 02118, USA., Sever P; International Centre for Circulatory Health, Imperial College London, London W2 1PG, UK., Sitlani CM; Cardiovascular Health Research Unit, Medicine, University of Washington, Seattle, WA 98101, USA., Smith JA; School of Public Health, Department of Epidemiology, University of Michigan, Ann Arbor, MI 48109, USA., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh EH8 9JZ, UK; Alzheimer Scotland Dementia Research Centre, The University of Edinburgh, Edinburgh EH8 9JZ, UK., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU Munich, Munich 81377, Germany., Tang H; Department of Genetics, Stanford University, Stanford, CA 94305, USA., Taylor KD; Genomic Outcomes, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Teo YY; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore 117549, Singapore; Genome Institute of Singapore, Agency for Science Technology and Research, Singapore 138672, Singapore; Life Sciences Institute, National University of Singapore, Singapore, Singapore 117456, Singapore; NUS Graduate School for Integrative Science and Engineering, National University of Singapore, Singapore 117456, Singapore; Department of Statistics and Applied Probability, National University of Singapore, Singapore 117546, Singapore., Tham YC; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore 169856, Singapore., Uitterlinden AG; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Waldenberger M; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany., Wang L; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO 63108, USA., Wang YX; Beijing Institute of Ophthalmology, Beijing Ophthalmology and Visual Science Key Lab, Beijing Tongren Eye Center, Capital Medical University, Beijing, China 100730, China., Wei WB; Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China., Williams C; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO 63108, USA., Wilson G; Jackson Heart Study, Department of Public Health, Jackson State University, Jackson, MS 39213, USA., Wojczynski MK; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO 63108, USA., Yao J; Genomic Outcomes, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Yuan JM; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA; Division of Cancer Control and Population Sciences, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15232, USA., Zonderman AB; Behavioral Epidemiology Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, NIH, Baltimore, MD 21224, USA., Becker DM; General Internal Medicine, GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI 48109, USA., Bowden DW; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK; Department of Cardiology, Ealing Hospital, Middlesex UB1 3HW, UK., Chen YI; Genomic Outcomes, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., de Faire U; Institute of Environmental Medicine, Karolinska Institutet, Stockholm 17177, Sweden., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, The University of Edinburgh, Edinburgh EH8 9JZ, UK; Department of Psychology, The University of Edinburgh, Edinburgh EH8 9JZ, UK., Esko T; Estonian Genome Center, University of Tartu, Tartu 51010, Estonia; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Boston, MA 02142, USA., Farrall M; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, Oxfordshire OX3 9DU, UK; Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Forrester T; Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona JMAAW15, Jamaica., Franks PW; Genetic and Molecular Epidemiology Unit, Department of Clinical Sciences, Lund University, Malmö, Skåne 205 02, Sweden; Harvard T.H. Chan School of Public Health, Department of Nutrition, Harvard University, Boston, MA 02115, USA; Department of Public Health & Clinical Medicine, Umeå University, Umeå, Västerbotten 901 85, Sweden., Freedman BI; Division of Nephrology, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA., Froguel P; CNRS UMR 8199, European Genomic Institute for Diabetes (EGID), Institut Pasteur de Lille, University of Lille, Lille 59000, France; Department of Genomics of Common Disease, Imperial College London, London W12 0NN, UK., Gasparini P; Department of Medical Sciences, University of Trieste, Trieste 34137, Italy; Division Experimental Genetics, Sidra, Doha 26999, Qatar., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg 85764, Germany; German Center for Diabetes Research (DZD e.V.), Neuherberg 85764, Germany., Horta BL; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, RS 96020220, Brazil., Hung YJ; Endocrinology and Metabolism, Tri-Service General Hospital, National Defense Medical Center, Taipei City, Taipei 11490, Taiwan., Jonas JB; Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China; Department of Ophthalmology, Medical Faculty Mannheim, University Heidelberg, Mannheim 68167, Germany., Kato N; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo 1628655, Japan., Kooner JS; Department of Cardiology, Ealing Hospital, Middlesex UB1 3HW, UK; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio 70210, Finland., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere 33520, Finland; Department of Clinical Chemistry, Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Lifes Sciences, University of Tampere, Tampere 33014, Finland., Liang KW; School of Medicine, National Yang-ming University, Taipei, Taiwan; Cardiovascular Center, Taichung Veterans General Hospital, Taichung 40705, Taiwan; Department of Medicine, China Medical University, Taichung 40705, Taiwan., Magnusson PKE; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm 17177, Sweden., Newman AB; Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA., Oldehinkel AJ; Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands., Pereira AC; Lab Genetics and Molecular Cardiology, Department of Cardiology, Heart Institute, University of Sao Paulo, Sao Paulo, Brazil; Genetics, Harvard Medical School, Boston, MA 02115, USA., Redline S; Sleep Medicine and Circadian Disorders, Brigham and Women's Hospital, Boston, MA 02115, USA., Rettig R; DZHK (German Center for Cardiovascular Research), partner site Greifswald, Greifswald 17475, Germany; Institute of Physiology, University Medicine Greifswald, Greifswald 17495, Germany., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester LE3 9QP, UK; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester LE3 9QP, UK., Scott J; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK., Shu XO; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37203, USA., van der Harst P; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen 9700 RB, the Netherlands., Wagenknecht LE; Department of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA., Wareham NJ; MRC Epidemiology Unit, University of Cambridge, Cambridge CB2 0QQ, UK., Watkins H; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, Oxfordshire OX3 9DU, UK; Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Weir DR; Institute for Social Research, Survey Research Center, University of Michigan, Ann Arbor, MI 48104, USA., Wickremasinghe AR; Department of Public Health, University of Kelaniya, Ragama, Sri Lanka., Wu T; Department of Occupational and Environmental Health and State Key Laboratory of Environmental Health for Incubating, School of Public Health, Tongji Medical College Huazhong University of Science and Technology, Wuhan, China., Zheng W; Division of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN 37203, USA., Kamatani Y; Laboratory for Statistical Analysis, Center for Integrative Medical Sciences, RIKEN, Yokohama 230-0045, Japan., Laurie CC; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA., Bouchard C; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA 70808, USA., Cooper RS; Department of Public Health Sciences, Loyola University Chicago, Maywood, IL 60153, USA., Evans MK; Health Disparities Research Section, Laboratory of Epidemiology and Population Sciences, National Institute on Aging, NIH, Baltimore, MD 21224, USA., Gudnason V; Icelandic Heart Association, Kopavogur 201, Iceland; Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland., Kardia SLR; School of Public Health, Department of Epidemiology, University of Michigan, Ann Arbor, MI 48109, USA., Kritchevsky SB; Sticht Center for Health Aging and Alzheimer's Prevention, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC 27157, USA., Levy D; Framingham Heart Study, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20982, USA; Population Sciences Branch, Division of Intramural Research, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20892, USA., O'Connell JR; Division of Endocrinology, Diabetes, and Nutrition, University of Maryland School of Medicine, Baltimore, MD 21201, USA; Program for Personalized and Genomic Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA., Psaty BM; Cardiovascular Health Research Unit, Epidemiology, Medicine and Health Services, University of Washington, Seattle, WA 98101, USA; Kaiser Permanente Washington, Health Research Institute, Seattle, WA 98101, USA., van Dam RM; Saw Swee Hock School of Public Health, National University of Singapore, Singapore 117549, Singapore; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore., Sims M; Jackson Heart Study, Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39213, USA., Arnett DK; Dean's Office, University of Kentucky College of Public Health, Lexington, KY 40536, USA., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden 2300RC, the Netherlands; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden 2300RC, the Netherlands., Kelly TN; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA 70112, USA., Fox ER; Cardiology, Department of Medicine, University of Mississippi Medical Center, Jackson, MS 39216, USA., Hayward C; Medical Research Council Human Genetics Unit, Institute of Genetics & Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK., Fornage M; Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Rotimi CN; Center for Research on Genomics and Global Health, National Human Genome Research Institute, NIH, Bethesda, MD 20892, USA., Province MA; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO 63108, USA., van Duijn CM; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Tai ES; Saw Swee Hock School of Public Health, National University Health System and National University of Singapore, Singapore, Singapore 117549, Singapore; Duke-NUS Medical School, Singapore 169857, Singapore; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 119228, Singapore., Wong TY; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore 169856, Singapore; Ophthalmology & Visual Sciences Academic Clinical Program (Eye ACP), Duke-NUS Medical School, Singapore, Singapore 169857, Singapore; Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore 117597, Singapore., Loos RJF; Icahn School of Medicine at Mount Sinai, The Charles Bronfman Institute for Personalized Medicine, New York, NY 10029, USA; Icahn School of Medicine at Mount Sinai, The Mindich Child Health and Development Institute, New York, NY 10029, USA., Reiner AP; Fred Hutchinson Cancer Research Center, University of Washington School of Public Health, Seattle, WA 98109, USA., Rotter JI; Genomic Outcomes, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, CA 90502, USA; Genomic Outcomes, Department of Medicine, LABioMed at Harbor-UCLA Medical Center, Torrance, CA 90502, USA., Zhu X; Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, OH 44106, USA., Bierut LJ; Department of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110, USA., Gauderman WJ; Division of Biostatistics, Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90032, USA., Caulfield MJ; William Harvey Research Institute, Clinical Pharmacology, Queen Mary University of London, London EC1M 6BQ, UK; NIHR Cardiovascular Biomedical Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK., Elliott P; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK; MRC-PHE Centre for Environment and Health, Department of Epidemiology & Biostatistics, School of Public Health, Imperial College London, London, UK., Rice K; Department of Biostatistics, University of Washington, Seattle, WA 98105, USA., Munroe PB; William Harvey Research Institute, Clinical Pharmacology, Queen Mary University of London, London EC1M 6BQ, UK; NIHR Barts Cardiovascular Biomedical Research Unit, Queen Mary University of London, London EC1M 6BQ, UK., Morrison AC; Department of Epidemiology, Human Genetics, and Environmental Sciences, The University of Texas School of Public Health, Houston, TX 77030, USA., Cupples LA; Department of Biostatistics, Boston University School of Public Health, Boston, MA 02118, USA; Framingham Heart Study, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD 20982, USA., Rao DC; Division of Biostatistics, Washington University School of Medicine, St. Louis, MO 63110, USA., Chasman DI; Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02215, USA. Electronic address: dchasman@research.bwh.harvard.edu.
Publikováno v:
American journal of human genetics [Am J Hum Genet] 2018 Mar 01; Vol. 102 (3), pp. 375-400. Date of Electronic Publication: 2018 Feb 15.