Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Andrea Eisen"'
Autor:
Wendy S. Meschino, Tari Little, Kelly A. Metcalfe, Jordan Lerner Ellis, Kathy Chun, Rinku Sutradhar, Andrea Eisen, Nancy N. Baxter, Lea Velsher, Fahima Dossa
Publikováno v:
CMAJ Open
Background: Our understanding of how testing for and mutations of the BRCA1 and BRCA2 genes affect cancer risk and the use of risk-reduction strategies comes largely from studies of women recruited from specialized genetics clinics. Our aim was to as
Autor:
Olivia Moran, Kelly A. Metcalfe, Kristina M. Blackmore, Ophira Ginsburg, Andrea Eisen, Joanne Kotsopoulos, Martin J. Yaffe, Rochelle Demsky, Steven A. Narod, Seema Panchal, Julia A. Knight, Kevin Zbuk
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-12 (2019)
BMC Cancer
BMC Cancer
Background Mammographic density is one of the strongest risk factors for breast cancer. In the general population, mammographic density can be modified by various exposures; whether this is true for women a strong family history is not known. Thus, w
Autor:
Kelly A. Metcalfe, Peter Ainsworth, Charis Eng, Andrea Eisen, Beth Y. Karlan, Tuya Pal, Pål Møller, Henry T. Lynch, Nadine Tung, Jan Lubinski, Wendy S. Meschino, Leigha Senter, Louise Bordeleau, Steven A. Narod, Ping Sun, Susan Armel, Ava Kwong, Jeffrey N. Weitzel
Publikováno v:
British Journal of Cancer
Background Women with a BRCA1 or BRCA2 mutation face high risks of breast and ovarian cancer. In the current study, we report on uptake of cancer screening and risk-reduction options in a cohort of BRCA mutation carriers from ten countries over two t
Autor:
Kelly A, Metcalfe, Andrea, Eisen, Aletta, Poll, Alexandra, Candib, David, McCready, Tulin, Cil, Frances, Wright, Rochelle, Demsky, Talia, Mancuso, Ping, Sun, Steven A, Narod
Publikováno v:
Annals of surgical oncology. 28(9)
There is an increasing desire for contralateral prophylactic mastectomy (CPM) among patients with unilateral breast cancer. It is unknown if risk assessment and genetic testing at the time of diagnosis will aid women in their surgical choice. We repo
Autor:
Tuya Pal, Jan Lubinski, Jacek Gronwald, Charis Eng, Andrea Eisen, Jeffrey N. Weitzel, Steven A. Narod, William D. Foulkes, Peter Ainsworth, Susan L. Neuhausen, Joanne Kotsopoulos, Leigha Senter, Nadine Tung, Henry T. Lynch, Christian F. Singer, Ping Sun
Publikováno v:
Breast cancer research and treatment. 171(2)
In the general population, an early age at first full-term birth confers protection against the risk of developing breast cancer. The relationship between age at first birth and breast cancer risk is not clear for women with a mutation in the BRCA1 o
Autor:
Jacqueline Lammert, Christine Elser, Joanne Kotsopoulos, Charis Eng, Ophira Ginsburg, Olufunmilayo I. Olopade, Tomasz Huzarski, Susan Armel, Stephanie A. Cohen, Marion Kiechle, Henry T. Lynch, William D. Foulkes, Wendy S. Meschino, Jan Lubinski, Steven A. Narod, Jacek Gronwald, Andrea Eisen, Carrie Snyder
Publikováno v:
Breast cancer research and treatment. 169(3)
Physical activity is inversely associated with the risk of breast cancer among women in the general population. It is not clear whether or not physical activity is associated with the risk of BRCA-associated breast cancer. We conducted a case–contr
Autor:
Matthew S. Lebo, Kathleen-Rose Zakoor, Kathy Chun, Marsha D. Speevak, John S. Waye, Elizabeth McCready, Jillian S. Parboosingh, Ryan E. Lamont, Harriet Feilotter, Ian Bosdet, Tracy Tucker, Sean Young, Aly Karsan, George S. Charames, Ronald Agatep, Elizabeth L. Spriggs, Caitlin Chisholm, Nasim Vasli, Hussein Daoud, Olga Jarinova, Robert Tomaszewski, Stacey Hume, Sherryl Taylor, Mohammad R. Akbari, Jordan Lerner-Ellis, Ron Agatep, Peter Ainsworth, Melyssa Aronson, Raveen Basran, Andre Blavier, Andrea Blumenthal, Kym Boycott, Michael Brudno, Kathleen Buckley, Jodi Campbell, Philippe M. Campeau, Melanie Care, Nancy Carson, Ronald Carter, George Charames, David Chitayat, George Chong, Edmond Chouinard, Kenneth J. Craddock, Rod Docking, Andrea Eisen, Hanna Faghfoury, Sandra Farrell, Bridget Fernandez, Marc Fiume, Cynthia Forster-Gibson, Jan Friedman, William Foulkes, Peter Goodhand, Jessica Gu, Robert Hegele, Spring Holter, Sheri Horsburgh, Lauren Hughes, Franny Jewett, Anne Junker, Sam Khalouei, Joan Knoll, Elena Kolomeitz, Bartha Knoppers, Ryan Lamont, Matthew Lebo, Georges Maire, Christian Marshall, Grant Mitchell, Michael J Moorhouse, Chantal Morel, Tanya Nelson, Abdul Noor, Brian O'Connor, Darren O'Rielly, Francis Ouellette, Jillian Parboosingh, Hilary Racher, Peter Ray, Heidi Rehm, Christie Riddell, Jean-Baptiste Riviere, David S. Rosenblatt, Guy Rouleau, Andrea Ruchon, Peter Sabatini, Bekim Sadikovic, Kara Semotiuk, Stephen W. Scherer, Cheryl Shuman, Josh Silver, Katherine Siminovitch, Lesley Solomon-Izsak, Jean-Francois Soucy, Marsha Speevak, James Stavropoulos, Lincoln Stein, Rhonda Tannenbaum, Deborah Terespolsky, Richard F. Wintle, Beatrix Wong, Nora Wong, Marina Wang, Nicholas Watkins, Shana White, Michael O. Woods, Philip Wyatt
Publikováno v:
Genetics in medicine : official journal of the American College of Medical Genetics. 20(3)
PurposeThe purpose of this study was to develop a national program for Canadian diagnostic laboratories to compare DNA-variant interpretations and resolve discordant-variant classifications using the BRCA1 and BRCA2 genes as a case study.MethodsBRCA1
Autor:
Eitan Friedman, Peter Ainsworth, Ava Kwong, Jacek Gronwald, Sofia D. Merajver, John Lunn, Andrea Eisen, Talia Donenberg, Wendy S. Meschino, Rochelle Demsky, Taya Fallen, Fergus J. Couch, Joanne L. Blum, Albert E. Chudley, Charis Eng, Raluca N. Kurz, Kelly A. Metcalfe, Mary B. Daly, Aletta Poll, Howard M. Saal, Louise Bordeleau, André Robidoux, A Jakubowska, Steven A. Narod, Tomasz Byrski, Claudine Isaacs, Charmaine Kim-Sing, Jane McLennan, Kenneth Offit, Dominique Stoppa-Lyonnet, Nadine Tung, Robert E. Reilly, Daniel Rayson, Edmond G. Lemire, Marie E. Wood, Jan Klijn, Siranoush Manoukian, Barry P. Rosen, Gad Rennert, Gareth Evans, Susan Armel, Ruth Gershoni-Baruch, Pål Møller, Jan Lubinski, Mark E. Robson, Sonia Nanda, Beth Y. Karlan, Barbara Pasini, Henry T. Lynch, Kevin Sweet, Leigha Senter, Christian F. Singer, Ping Sun, Judy Garber, Lovise Maehle, Josephine Wagner Costalas, Ophira Ginsburg, Dawna Gilchrist, Tomasz Huzarski, Wendy McKinnon, Jeffrey N. Weitzel, William D. Foulkes, Susan L. Neuhausen, Noah D. Kauff, Christine Rappaport, Carey A. Cullinane, David M. Euhus, Tuya Pal, Dana Zakalik, Olufunmilayo I. Olopade, Seema Panchal, Cezary Cybulski, Susan T. Vadaparampil
Publikováno v:
Breast Cancer Research and Treatment. 146:421-427
Women with a mutation in BRCA1 or BRCA2 face a lifetime risk of breast cancer of approximately 80 %. Tamoxifen treatment of the first cancer has been associated with a reduction in the risk of a subsequent contralateral cancer. We studied 1,504 women
Autor:
Susan Armel, Andrea Eisen, Steven A. Narod, William D. Foulkes, Sun Ping, Nadine Tung, Ganna Chornokur, Javaid Iqbal, Jacek Gronwald, Leigha Senter, Catherine M. Phelan, Peter Möller, Jan Lubinski, Peter Ainsworth, Susan L. Neuhausen, M. Llacuachaqui, Henry T. Lynch, Christian F. Singer, Charmaine Kim-Sing, Parviz Ghadirian
Publikováno v:
British Journal of Cancer
The BRCA1 and BRCA2 genes confer increased susceptibility to breast and ovarian cancers (Wooster et al, 1995; Ford et al, 1998; Satagopan et al, 2001; Thompson et al, 2001; Antoniou et al, 2003) and to a spectrum of other cancers (Struewing et al, 19
Autor:
Tari Little, Nancy N. Baxter, Rinku Sutradhar, Andrea Eisen, Jordan Lerner-Ellis, Fahima Dossa, Wendy S. Meschino, Maria C. Cusimano, Kelly A. Metcalfe
Publikováno v:
BMJ Open
IntroductionWomen who have pathogenic mutations in theBRCA1andBRCA2genes are at greatly increased risks for breast and ovarian cancers. Although risk-reduction strategies can be undertaken by these women, knowledge regarding the uptake of these strat