Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Richard Salvi"'
Autor:
Richard Salvi, Kelly Radziwon, Guang-Di Chen, Dalian Ding, Benjamin D. Auerbach, Xiaopeng Liu
Publikováno v:
Neuroscience
Noise-induced hearing loss generally induces loudness recruitment, but sometimes gives rise to hyperacusis, a debilitating condition in which moderate intensity sounds are perceived abnormally loud. In an attempt to develop an animal model of loudnes
Publikováno v:
Neurotox Res
Paraquat, a superoxide generator, can damage the cochlea causing an ototoxic hearing loss. The purpose of the study was to determine if deletion of Bak, a pro-apoptotic gene, would reduce paraquat ototoxicity or if deletion of Sirt3, which delays age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5198635a5e5780e596a3acdf24cd7f64
https://europepmc.org/articles/PMC8277768/
https://europepmc.org/articles/PMC8277768/
Publikováno v:
Neuroscience. 407:135-145
The central auditory system shows a remarkable ability to rescale its neural representation of loudness following long-term, low-level acoustic exposures; even when the noise is presented intermittently. Circadian rhythms exert potent biological effe
Autor:
Richard Salvi, Larry E. Roberts
Publikováno v:
Neuroscience. 407:1-7
Publikováno v:
Journal of Neurophysiology. 121:893-907
Electrophysiological and imaging studies from humans suggest that the phantom sound of tinnitus is associated with abnormal thalamocortical neural oscillations (dysrhythmia) and enhanced gamma band activity in the auditory cortex. However, these mode
Publikováno v:
Neuroscience. 399:184-198
The cochlear nucleus, located in the brainstem, receives its afferent auditory input exclusively from the auditory nerve fibers of the ipsilateral cochlea. Noise-induced neurodegenerative changes occurring in the auditory nerve stimulate a cascade of
Autor:
Dong Li, Haibo Shi, Hong Sun, Haiyan Jiang, Xuewen Wu, Weiluo Huang, Peng Li, Dalian Ding, Richard Salvi, Jintao Yu, Weidong Qi, Jianhui Zhang, Wenjuan Li, Fang Liu
Publikováno v:
J Neurophysiol
Auditory brain stem response (ABR) and compound action potential (CAP) recordings have been used in animal research to determine hearing sensitivity. Because of the relative ease of testing, the ABR test has been more commonly used in assessing cochl
Publikováno v:
Neurotox Res
2-Hydroxypropyl-β-cyclodextrin (HPβCD), a cholesterol chelator, is being used to treat diseases associated with abnormal cholesterol metabolism such as Niemann-Pick C1 (NPC1). However, the high doses of HPβCD needed to slow disease progression may
Publikováno v:
Neuroscience
Unilateral noise-induced hearing loss reduces the input to the central auditory pathway disrupting the excitatory and inhibitory inputs to the inferior colliculus (IC), an important binaural processing center. Little is known about the compensatory s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a62932a416f401c24b110601690c7664
http://hdl.handle.net/11573/1410127
http://hdl.handle.net/11573/1410127
Autor:
Shinichi Someya, Sanford L. Boye, Kaitlyn R. Calabro, Dalian Ding, Mi-Jung Kim, Richard Salvi, Sean Crosson, Diego Fajardo, Shannon E. Boye, Shreyasi Choudhury, Jim Peterson, Wei Li
Publikováno v:
Frontiers in Neuroscience
Frontiers in Neuroscience, Vol 13 (2019)
Frontiers in Neuroscience, Vol 13 (2019)
Usher's syndrome is the most common combined blindness-deafness disorder with USH1B, caused by mutations in MYO7A, resulting in the most severe phenotype. The existence of numerous, naturally occurring shaker1 mice harboring variable MYO7A mutations