Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Megumi Aimoto"'
Publikováno v:
Biological and Pharmaceutical Bulletin. 44:707-713
High salt intake has been shown to induce hypertrophy and fibrosis in the atria and ventricles, which could result in the development of atrial fibrillation (AF). Whereas the development of AF is suggested to be prevented by renin-angiotensin system
Autor:
Megumi Aimoto, Keita Yagi, Aya Ezawa, Yayoi Tsuneoka, Kohei Kumada, Takeshi Hasegawa, Tetsuo Kuze, Toshiki Chiba, Yoshinobu Nagasawa, Hikaru Tanaka, Akira Takahara
Publikováno v:
Biologicalpharmaceutical bulletin. 45(5)
Atrial enlargement is thought to provide arrhythmogenic substrates, leading to the induction of atrial fibrillation (AF). In this study, we investigated the anatomical, molecular biological, and electrophysiological characteristics of remodeled atria
Publikováno v:
Biologicalpharmaceutical bulletin. 45(4)
Cardiac electropharmacological effects of an antidiarrheal drug loperamide and its antidote naloxone were assessed in isoflurane-anesthetized guinea pigs. Intravenous administration of loperamide at 0.01-0.1 mg/kg did not affect parameters of electro
Publikováno v:
Biologicalpharmaceutical bulletin. 44(11)
Torsadogenic effects of ivabradine, an inhibitor of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, were assessed in an in vivo proarrhythmia model of acute atrioventricular block rabbit. Ivabradine at 0.01, 0.1, and 1 mg/kg was i
Publikováno v:
Biologicalpharmaceutical bulletin. 44(8)
Aldosterone induces cardiac electrical and structural remodeling, which leads to the development of heart failure and/or atrial fibrillation (AF). However, it remains unknown whether aldosterone-induced remodeling may modulate the efficacy of anti-AF