Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hiromasa, Yoshioka"'
Publikováno v:
Anticancer Research. 42:4173-4178
Standard treatment options for primary central nervous system lymphoma (PCNSL) include high-dose methotrexate (HD-MTX)-based drug therapy and whole-brain radiation therapy. However, there are many cases in which these standard treatment options are n
Autor:
Hiromasa Yoshioka, Tatsuro Kawamura, Makoto Muroi, Yasumitsu Kondoh, Kaori Honda, Makoto Kawatani, Harumi Aono, Herbert Waldmann, Nobumoto Watanabe, Hiroyuki Osada
Publikováno v:
ACS chemical biology. 17(2)
Glutathione peroxidase 4 (GPX4) is an intracellular enzyme that oxidizes glutathione while reducing lipid peroxides and is a promising target for cancer therapy. To date, several GPX4 inhibitors have been reported to exhibit cytotoxicity against canc
Publikováno v:
Anticancer research. 41(8)
Background/aim Leptomeningeal carcinomatosis (LMC) with hydrocephalus is particularly difficult to treat, and its prognosis is extremely poor. The therapeutic outcomes of 14 patients with LMC-associated hydrocephalus who were treated with cerebrospin
Publikováno v:
Anticancer research. 40(8)
Background/aim Recent advances in systemic chemotherapy, including molecularly targeted therapy, have dramatically improved survival for patients with advanced non-small cell lung cancer. We retrospectively analyzed the clinical outcomes of surgical
Autor:
Takeshi Okuda, Shuichi Izumoto, Kimihiro Yamashita, Mitsugu Fujita, Susumu Nakata, Takayuki Tasaki, Hiromasa Yoshioka, Amami Kato
Publikováno v:
Anticancer research. 37(7)
Background Glioblastoma multiforme (GBM) is a malignant brain tumor with an extremely poor prognosis. GBM tissues frequently express mesenchymal-epithelial transition factor (MET), which induces cell division, growth and migration. In addition, angio
Publikováno v:
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. 19(12)
We have developed a technique of fluorescence-guided surgery using high-dose fluorescein sodium (20mg/kg) with excitation and barrier filters for glioblastoma multiforme surgery. This technique was used in 10 patients, with surgery proceeding as expe