Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Chee-Wai Chua"'
Autor:
Michael M. Shen, Hanina Hibshoosh, Antonina Mitrofanova, Bo I. Li, Chee Wai Chua, Eva Leung, Nusrat J. Epsi, Ming Lei, Sarah K. Bergren, Shouhong Xuan
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
Master regulatory genes of tissue specification play key roles in stem/progenitor cells and are often important in cancer. In the prostate, androgen receptor (AR) is a master regulator essential for development and tumorigenesis, but its specific fun
Autor:
Yong-Chuan Wong, Yung-Tuen Chiu, Ming-Tat Ling, Kwok Wah Chan, Chee-Wai Chua, Hiu-Fung Yuen, Xianghong Wang
Publikováno v:
APMIS. 118:918-926
One of the common features in advanced prostate cancer is bone metastasis. In this study, we investigated the clinical relevance of a bone factor, MSX2, in predicting the metastatic ability of prostate adenocarcinoma. Evaluation of MSX2 expression wa
Autor:
Xianghong Wang, WK Kwok, Ying-Ying Chu, Kwok Wah Chan, Hiu-Fung Yuen, Chee-Wai Chua, Ka-Kui Chan, Yuen-Piu Chan, Yong-Chuan Wong
Publikováno v:
Carcinogenesis. 29:1509-1518
TWIST, a helix-loop-helix transcription factor, is highly expressed in many types of human cancer. We have previously found that TWIST confers prostate cancer cells with an enhanced metastatic potential through promoting epithelial-mesenchymal transi
Publikováno v:
Histopathology. 50:648-658
Aim: Development of metastasis is one of the main causes of prostatic cancer-related death. We have previously found that up-regulation of TWIST, a highly conserved basic helix–loop–helix transcription factor, in prostatic cancer cells can promot
Autor:
Xuesong Li, Dianqi Xin, Yanqun Na, Zheng Zhang, Steve C.L. Leung, Chee Wai Chua, Xianghong Wang, Yong-Chuan Wong
Publikováno v:
Histopathology. 50:484-490
Aims: Epidermal growth factor receptor (EGFR) is suggested as one of the positive regulators in the invasive progression of renal cell cancer (RCC). Recently, Id-1 (inhibitor of differentiation or DNA binding), a helix-loop-helix transcription factor
Autor:
K X Xu, Yong-Chuan Wong, Ming-Tat Ling, Xiaopeng Zhang, Huiying Han, Hao Hu, Xiao-feng Wang, Yu Liang Wang, Chee Wai Chua
Publikováno v:
Oncology reports. 21(4)
Recurrence and progression are the major problems in the treatment of bladder cancer. Increased expression of Id-1, a basic helix-loop-helix transcription factor, has recently been shown in several types of advanced cancer. Some studies have provided
Autor:
Xianghong Wang, Kwok Wah Chan, Edward W. Howard, Yong-Chuan Wong, Hiu-Fung Yuen, Steve C.L. Leung, Davy T. Lee, Chee Wai Chua
Publikováno v:
Clinicalexperimental metastasis. 25(5)
The presence of circulating tumor cells (CTC) is common in prostate cancer patients, however until recently their clinical significance was unknown. The CTC stage is essential for the formation of distant metastases, and their continuing presence aft
Autor:
Tracy C.M. Lau, Qi Wang, Yong-Chuan Wong, Chee Wai Chua, WK Kwok, Ming-Tat Ling, Xianghong Wang, Chun Zhou
Publikováno v:
Carcinogenesis. 26(10)
Androgen-independent metastatic prostate cancer is the main cause of cancer related death in men. One of the reasons for this is the lack of understanding of the molecular mechanisms leading to the metastatic progression of prostate cancer. In this s