Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Crispin A"'
Autor:
Crispin Jenkinson, Ray Fitzpatrick, Chidiebere Hope Nwolise, Avinash Gupta, Rubeta N Matin, Pippa Corrie, Mark R. Middleton
Publikováno v:
Chronic Illness. 19:81-94
Peer reviewed: True
Funder: National Institute for Health Research (NIHR) Research for Patient Benefit (RfPB); Grant(s): Grant Reference Number: PB-PG-0815-20048
OBJECTIVE: A qualitative sub-study was carried out within a larger phase II fe
Funder: National Institute for Health Research (NIHR) Research for Patient Benefit (RfPB); Grant(s): Grant Reference Number: PB-PG-0815-20048
OBJECTIVE: A qualitative sub-study was carried out within a larger phase II fe
Autor:
Hélène Mahenzi Mbembo, Mathieu Nkieri Matsho, Bruno Scherrer, Steven Lumeya Vuvu, Wilfried Mutombo Kalonji, Franck Botalema Bolengi, Olaf Valverde Mordt, Sonja Bernhard, Sophie Delhomme, Séverine Blesson, Antoine Tarral, Tim Mayala Malu, Clélia Bardonneau, Serge Kapongo Tshilumbwa, Dieudonné Mpoyi Muamba Nzambi, Felix Akwaso Masa, François Simon, Melchias Mukendi Ilunga, Crispin Lumbala, Digas Ngolo Tete, Nathalie Strub-Wourgaft, Victor Kande Betu Ku Mesu, Christian Mpia Moke, Junior Mudji E'kitiak
Publikováno v:
The Lancet. Global Health
The Lancet Global Health, Vol 9, Iss 7, Pp e999-e1008 (2021)
The Lancet Global Health, Vol 9, Iss 7, Pp e999-e1008 (2021)
Summary Background Staging and treatment of human African trypanosomiasis caused by Trypanosoma brucei gambiense (g-HAT) required lumbar puncture to assess cerebrospinal fluid (CSF) and intravenous drugs that cross the blood–brain barrier for late-
Autor:
Saba Ferdous, Charles Swanton, Francesca Chemi, Chang Sik Kim, Selvaraju Veeriah, Ged Brady, Sakshi Gulati, Deborah J. Burt, Mariam Jamal-Hanjani, Fiona H Blackhall, Daniel Slane-Tan, Nicholas McGranahan, Jackie Pierce, Marek Dynowski, Crispin J. Miller, Barbara Mesquita, Dominic G. Rothwell, Cong Zhou, David Allan Moore, Simon P. Pearce, Fabio Gomes, Philip A.J. Crosbie, Jonathan Tugwood, Nicolai Juul Birkbak, R. Shah, Gareth A. Wilson, Christopher Abbosh, Sophia Ward, Maise Al Bakir, Allan Hackshaw, Crispin T. Hiley, Caroline Dive, Dhruva Biswas, Yvonne Summers
Publikováno v:
Chemi, F, Rothwell, D G, McGranahan, N, Gulati, S, Abbosh, C, Pearce, S P, Zhou, C, Wilson, G A, Jamal-Hanjani, M, Birkbak, N, Pierce, J, Kim, C S, Ferdous, S, Burt, D J, Slane-Tan, D, Gomes, F, Moore, D, Shah, R, Al Bakir, M, Hiley, C, Veeriah, S, Summers, Y, Crosbie, P, Ward, S, Mesquita, B, Dynowski, M, Biswas, D, Tugwood, J, Blackhall, F, Miller, C, Hackshaw, A, Brady, G, Swanton, C, Dive, C & TRACERx Consortium 2019, ' Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse ', Nature Medicine, vol. 25, no. 10, pp. 1534-1539 . https://doi.org/10.1038/s41591-019-0593-1
TRACERx Consortium 2019, ' Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse ', Nature Medicine, vol. 25, no. 10, pp. 1534-1539 . https://doi.org/10.1038/s41591-019-0593-1
TRACERx Consortium 2019, ' Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse ', Nature Medicine, vol. 25, no. 10, pp. 1534-1539 . https://doi.org/10.1038/s41591-019-0593-1
Approximately 50% of patients with early-stage non-small-cell lung cancer (NSCLC) who undergo surgery with curative intent will relapse within 5 years1,2. Detection of circulating tumor cells (CTCs) at the time of surgery may represent a tool to iden
Autor:
Charles McDonald, John Napoli, Thomas J. Borody, Rupert W. Leong, Webber Chan, Peter H. Katelaris, Anil Keshava, Daniel A. Lemberg, Aviv Pudipeddi, Sudarshan Paramsothy, Viraj C. Kariyawasam, Crispin Corte, Robert Clancy, Cheng H Lee, Grace Chapman, Jeffrey Liu, James L. Cowlishaw
Publikováno v:
Medical Journal of Australia. 214:365-370
Objectives To determine the age-standardised prevalence of inflammatory bowel disease (IBD) in a metropolitan area of Sydney, with a focus on its prevalence among older people. Design, setting Population-based epidemiological study of people with IBD
Autor:
Christian Tesche, Ullrich Ebersberger, Alexander Crispin, Stefan Hartl, Florian Straube, Thomas K. Helmberger, Benedikt Brueck, Michael Wankerl, Janis Pongratz, Uwe Dorwarth, Ellen Hoffmann
Publikováno v:
Clinical Cardiology
Background Left atrial appendage (LAA) is a potential source of atrial fibrillation (AF) triggers. Hypothesis LAA morphology and dimensions are associated with AF recurrence after pulmonary vein isolation (PVI). Methods From cardiac computed tomograp
Autor:
Callixte Habimana, Louise R. King, Samuel Byiringiro, Crispin Gishoma, Pamela Meharry, Olive Tengera, Stephen Rulisa, Paul J. Nietert, Adolphe Karegeya Byambu
Publikováno v:
Diabetes Res Clin Pract
Aim This study aimed to determine the prevalence of gestational diabetes mellitus (GDM) among women attending public health centers in Rwanda using the World Health Organization (WHO) 2013 diagnostic criteria. Methods A cross-sectional analysis was p
Autor:
Kristopher K. Frese, Donna M. Graham, Nicholas Hickson, Alexandra Clipson, Crispin J. Miller, Sumitra Mohan, Saba Ferdous, Matthew G Krebs, Alexander J Vickers, Bedirhan Kilerci, Helen Eaton, Caroline Dive, Siobhan Southam, Roopa Kurup, Hannah Frost, Ciara O’Brien, Fiona C Thistlethwaite, Richard Marais, Allan M. Jordan, Mahmood Ayub, Robert Metcalf, Jaseela Chiramel, Louise Carter, Daniel J. White, Emma Dean, Matthew Howell, Sreeja Aruketty, Avinash Gupta, Joanne Dransfield, Ged Brady, Kamrun Nessa, Donal Landers, Claire L. S. Kelly, Shaun Villa, Julie Stevenson, Dominic G. Rothwell, Nigel K Smith, Andrew Hughes, Nadina Tinsley, Natalie Cook, Sakshi Gulati, Andrew L. Wallace
Publikováno v:
Rothwell, D, Ayub, M, Cook, N, Thistlethwaite, F, Carter, L, Dean, E, Smith, N, Villa, S, Dransfield, J, Clipson, A, White, D, Nessa, K, Ferdous, S, Howell, M, Gupta, A, Kilerci, B, Mohan, S, Frese, K, Gulati, S, Miller, C, Jordan, A, Eaton, H, Hickson, N, O'Brien, C, Graham, D, Kelly, C, Aruketty, S, Metcalf, R, Chiramel, J, Tinsley, N, Vickers, AJ, Kurup, R, Frost, H, Stevenson, J, Southam, S, Landers, D, Wallace, A, Marais, R, Hughes, AM, Brady, G, Dive, C & Krebs, M 2019, ' Utility of ctDNA to support patient selection for early phase clinical trials: The TARGET Study ', Nature Medicine, vol. 25, no. 5, pp. 738-743 . https://doi.org/10.1038/s41591-019-0380-z, https://doi.org/10.1038/s41591-019-0380-z
Next-generation sequencing (NGS) of circulating tumor DNA (ctDNA) supports blood-based genomic profiling but is not yet routinely implemented in the setting of a phase I trials clinic. TARGET is a molecular profiling program with the primary aim to m
Autor:
Christoph B. Westphalen, Leonie Gebauer, Karoline Schirle, Volker Heinemann, Julia Mayerle, Stefan Boeck, Matthias Ilmer, Jan G. D’Haese, Sebastian Kobold, Michael von Bergwelt-Baildon, Thomas Kirchner, Michael Haas, Stephan Kruger, Jens Ricke, Jens Werner, Jörg Schirra, Steffen Ormanns, Alexander Crispin, Wolfgang G. Kunz
Publikováno v:
Journal of cancer research and clinical oncology. 146(2)
A prolonged time to treatment initiation (TTI) correlates with an adverse prognosis in different cancer types including resectable pancreatic cancer (PC). Only limited evidence on the correlation between TTI and prognosis in advanced PC exists. Conse
Autor:
Bruno Scherrer, Victor Kande Betu Ku Mesu, Crispin Lumbala, Olaf Valverde Mordt, Nathalie Strub-Wourgaft, Wilfried Mutombo Kalonji, Séverine Blesson, Willy Kuziena, Jean Pierre Fina Lubaki, Steven Lumeya Vuvu, Pathou Nganzobo Ngima, Augustin Kasongo Bonama, François Simon, Lewis Kaninda Badibabi, Jean Louis Lumaliza Solomo, Medard Ilunga, Sonja C. Bernhard, Francis Regongbenga Dama, Josué Amici Heradi, Guylain Mandula, Papy Kavunga Lukula, Clélia Bardonneau, Hélène Mahenzi Mbembo, Digas Ngolo Tete, Sophie Delhomme, Antoine Tarral
Publikováno v:
The Lancet. 391:144-154
Summary Background Few therapeutic options are available to treat the late-stage of human African trypanosomiasis, a neglected tropical disease, caused by Trypanosoma brucei gambiense (g-HAT). The firstline treatment is a combination therapy of oral
Publikováno v:
Diabetes Research and Clinical Practice. 178:108929
Aim To estimate the incidence and prevalence of nephropathy and investigate whether high and fluctuating HbA1c levels were associated with development of nephropathy among T1 diabetes individuals in Rwanda. Methods From 2009 to 2018, 471 T1 diabetes