Zobrazeno 1 - 2
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pro vyhledávání: '"Maria Gabriella Gabrielli"'
Autor:
G Fasolis, Maria Gabriella Gabrielli, del Vecchio Mt, R Rossie, Luca Puccetti, S.A. Tripodi, Silvia Pastorekova, and Andrea Scozzafava, C.T. Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry. 19:287-291
Clear renal cell carcinomas (RCC) frequently express carbonic anydrase IX (CA IX) because of non-functional mutation of von Hippel Lindau (VHL) tumor suppressor gene. CA IX is a tumor-associated transmembrane antigen, which catalyzes the extracellula
Publikováno v:
Journal of enzyme inhibition and medicinal chemistry. 29(1)
Studies on the mechanisms of saliva secretion have indicated that carbonic anhydrase (CA) is expressed in mammalian salivary glands. The enzyme is present in the saliva as the only known secretory isoenzyme, CAVI; its activity has been related to the