Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Ying Zhuo"'
Publikováno v:
Chemical Science. 14:2318-2324
We designed two functionalized tetrahedral DNA nanostructures (f-TDN1 and f-TDN2), which could assemble into giant DNA networks triggered by APE1, achieving sensitive detection and intracellular imaging of APE1 as well as gene therapy.
Publikováno v:
Chinese Chemical Letters. 33:4803-4807
Publikováno v:
Chinese Chemical Letters. 34:107957
Autor:
Jason Micklefield, Ying Zhuo, Katherine J Robins, Yingxin Zhang, Joanna K Fyans, Brian J. C. Law, Wei Li Thong, Abigail J Herbert
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Thong, W L, Zhang, Y, Zhuo, Y, Robins, K J, Fyans, J K, Herbert, A J, Law, B J C & Micklefield, J 2021, ' Gene editing enables rapid engineering of complex antibiotic assembly lines ', Nature Communications, vol. 12, no. 1, 6872 . https://doi.org/10.1038/s41467-021-27139-1
Nature Communications
Thong, W L, Zhang, Y, Zhuo, Y, Robins, K J, Fyans, J K, Herbert, A J, Law, B J C & Micklefield, J 2021, ' Gene editing enables rapid engineering of complex antibiotic assembly lines ', Nature Communications, vol. 12, no. 1, 6872 . https://doi.org/10.1038/s41467-021-27139-1
Nature Communications
Re-engineering biosynthetic assembly lines, including nonribosomal peptide synthetases (NRPS) and related megasynthase enzymes, is a powerful route to new antibiotics and other bioactive natural products that are too complex for chemical synthesis. H
Autor:
Lingling Jiang, Jiale Zhang, Hongying Li, Chaoqin He, Ruo Yuan, Yingqi Zhao, Jian-An Huang, Ying Zhuo, Xia Yang
Publikováno v:
Chemical Engineering Journal. 461:142102
Publikováno v:
ChemPlusChem. 87
Mediated by Watson-Crick base-pairing principle, DNA can be used to construct multi-functional molecular machines, such as DNA walkers, tweezers, logic gates and motors. It is noteworthy that DNA walkers with the advantages of programmability and div
Autor:
Ruo Yuan, Yaqin Chai, Beibei Kou, Ying Zhuo, Ding Wang, Ling-Qi Kong, Xiaolong Zhang, Yali Yuan
Publikováno v:
Chemical Science
A highly loaded and integrated core–brush three-dimensional (3D) DNA nanostructure is constructed by programmatically assembling a locked DNA walking arm (DA) and hairpin substrate (HS) into a repetitive array along a well-designed DNA track genera
Autor:
Zhehan Yang, Zhenjia Yang, Xiaoshu Lv, Guangming Jiang, Xiaolong Zhang, Xiaodan Li, Xiaoyu Li, Ruo Yuan, Ying Zhuo
Publikováno v:
Chemical Engineering Journal. 454:140490
Publikováno v:
Chemical Engineering Journal. 450:138284
Publikováno v:
Chemical Science
Herein, a Janus three-dimensional (3D) DNA nanomachine was constructed for the simultaneous and sensitive fluorescence detection and imaging of dual microRNAs (miRNAs) in cancer cells, which could effectively eliminate signal interference in a homoge