Zobrazeno 1 - 4
of 4
pro vyhledávání: '"David Dilworth"'
Autor:
Ronan P. Hanley, David Y. Nie, John R. Tabor, Fengling Li, Amin Sobh, Chenxi Xu, Natalie K. Barker, David Dilworth, Taraneh Hajian, Elisa Gibson, Magdalena M. Szewczyk, Peter J. Brown, Dalia Barsyte-Lovejoy, Laura E. Herring, Gang Greg Wang, Jonathan D. Licht, Masoud Vedadi, Cheryl H. Arrowsmith, Lindsey I. James
Publikováno v:
Journal of the American Chemical Society. 145:8176-8188
Autor:
Hideto Fukushi, Masayuki Takizawa, Shawna Organ, Masoud Vedadi, Peter Brown, Rima Al-awar, Carlo C. dela Seña, Mike Tyers, Carlos Zepeda, Levon Halabelian, David Dilworth, Suzanne Ackloo, Ahmed Aman, Amber L. Couzens, Yoshinori Ishikawa, David Macleod, Nozomu Sakai, Rachel Harding, Stéphane Richard, Tsukasa Sugo, Anne-Claude Gingras, Hiroshi Nara, Fengling Li, Eric Bonneil, Mohammad S. Eram, Cheryl H. Arrowsmith, Shinji Takagi, Dalia Barsyte-Lovejoy, María Sánchez-Osuna, Kozo Hayashi, Magdalena M. Szewczyk
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Protein arginine methyltransferases (PRMTs) regulate diverse biological processes and are increasingly being recognized for their potential as drug targets. Here we report the discovery of a potent, selective, and cell-active chemical probe for PRMT7
Autor:
Levon Halabelian, Nozomu Sakai, David McLeod, Anne-Claude Gingras, Rima Al-awar, Hiroshi Nara, Dalia Barsyte-Lovejoy, Masoud Vedadi, David Dilworth, Hideto Fukushi, Stéphane Richard, Carlos Zepeda, Cheryl H. Arrowsmith, María Sánchez-Osuna, Ahmed Aman, Carlo C. dela Seña, Kozo Hayashi, Suzanne Ackloo, Magdalena M. Szewczyk, Yoshinori Ishikawa, Peter Brown, Fengling Li, Eric Bonneil, Mike Tyers, Mohammad S. Eram, Masayuki Takizawa, Amber L. Couzens, Shawna Organ, Rachel Harding, Shinji Takagi, Tsukasa Sugo
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-1 (2020)
Protein arginine methyltransferases (PRMTs) regulate diverse biological processes and are increasingly being recognized for their potential as drug targets. Here we report the discovery of a potent, selective, and cell-active chemical probe for PRMT7
Autor:
Ernesto Guccione, Philipp Kaldis, Dalia Barsyte-Lovejoy, Danton Ivanochko, Magdalena M. Szewczyk, David Dilworth, Matthieu Schapira, Peter Loppnau, S. Zakiah A. Talib, Fengling Li, Solomon Kattar, Levon Halabelian, Ronan C. O'Hagan, Jabez Bok, Levi L. Blazer, Evelyne Lima-Fernandes, Genna M. Luciani, Nathan Palmer, Mohammad S. Eram, Cheryl H. Arrowsmith, Benjamin Nicholson, John M. Sanders, Peter Brown, Abdellah Allali-Hassani, Masoud Vedadi, Shawna Organ, Jessica Sook Yuin Ho, D. Jonathan Bennett, Qin Wu
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications
Nature Communications
PRDM9 is a PR domain containing protein which trimethylates histone 3 on lysine 4 and 36. Its normal expression is restricted to germ cells and attenuation of its activity results in altered meiotic gene transcription, impairment of double-stranded b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33e807d4565f7990902109995ea70c8
https://vb.gamtc.lt/GTC:ELABAPDB54740056&prefLang=en_US
https://vb.gamtc.lt/GTC:ELABAPDB54740056&prefLang=en_US