Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hatem A. Abuelizz"'
Autor:
Mohamed Marzouk, Hanan A. A. Taie, Rashad Al-Salahi, Adi Ahudhaif, Hatem A. Abuelizz, El Hassane Anouar
Publikováno v:
Chemical Papers. 74:2893-2899
The target 2-phenoxy[3,2-e][1,2,4]triazolo[1,5-a]pyrimidines (1–6) was previously synthesized and fully characterized. In the present study, the antioxidant activity of compounds 1–6 was evaluated using 1,1-diphenyl-2-picryl hydrazyl (DPPH) radic
Autor:
Mona M. Al-Shehri, Hamad M. Alkahtani, Mostafa Mohammed, Hatem A. Abuelizz, Adeeba Alzamil, Mohamed M. Hefnawy, M. A. Abounassif, Nawaf A. Alsaif, Abdulrahman A. Almehizia
Publikováno v:
Arabian Journal of Chemistry, Vol 13, Iss 2, Pp 4024-4034 (2020)
A sensitive and selective UHPLC-MS/MS method was developed and validated to simultaneously determine of palbociclib (PLB), letrozole (LTZ) and its metabolite carbinol (CBL) in rat plasma. After sample pre-treatment by acetonitrile-protein precipitati
Autor:
Hatem A. Abuelizz, Ahmed H. Bakheit, Adnan A. Kadi, Thamer A. Alsubi, Mohamed W. Attwa, Hany W. Darwish
Publikováno v:
RSC Advances. 10:22668-22683
Ribociclib (RBC, Kisqali®) is a highly selective CDK4/6 inhibitor that has been approved for breast cancer therapy. Initially, prediction of susceptible sites of metabolism and reactivity pathways were performed by the StarDrop WhichP450™ module a
Publikováno v:
RSC Advances. 10:35820-35830
Morbidity and mortality due to hepatitis C virus (HCV) is a globe health concern. Hence, there is a persistent demand to design and optimize current HCV therapy and develop novel agents. HCV NS3/A4 protease plays an essential role in HCV life cycle a
Autor:
Hatem A. Abuelizz, Gamal A. E. Mostafa, Ahmed H. Bakheit, Harunor Rashid, Mohamed Marzouk, Rashad Al-Salahi, Hanan A. A. Taie
Publikováno v:
ACS Omega
ACS Omega, Vol 6, Iss 47, Pp 31993-32004 (2021)
ACS Omega, Vol 6, Iss 47, Pp 31993-32004 (2021)
Hydrazinobenzoic acid derivatives with isothiocyanate, benzylidene, and acid anhydride core units (1–13) were previously synthesized and fully characterized. Targets 1–13 were investigated for their antioxidant activities using different in vitro
Autor:
Ahmed H. Bakheit, Ahmed M. Naglah, Fahd A. Nasr, Hatem A. Abuelizz, Hanem M. Awad, Rashad Al-Salahi, Ali S. Alqahtani, Mohamed Marzouk
Publikováno v:
RSC Advances. 9:19065-19074
A series of 4-(1H-1,2,4-triazol-1-yl)benzoic acid hybrids (1–17) was successfully synthesized and their structures were established by NMR and MS analysis. In vitro cytotoxic evaluation indicated that some of the hybrids exhibited potent inhibitory
Autor:
Mohamed Marzouk, Hatem A. Abuelizz, Saied M. Soliman, Rashad Al-Salahi, Mohamed Abdellatif, Hazem A. Ghabbour
Publikováno v:
Crystals
Volume 11
Issue 10
Crystals, Vol 11, Iss 1195, p 1195 (2021)
Volume 11
Issue 10
Crystals, Vol 11, Iss 1195, p 1195 (2021)
The present work aimed to synthesize 2-methylthio-triazoloquinazoline derivatives and study their X-ray, NMR, DFT and Hirshfeld characteristics. The cyclocondensation of dimethyl-N-cyanodithiocarbonate with 2-hydrazinobenzoic acid hydrochloride resul
Autor:
Thamer A. Alsubi, Mohamed W. Attwa, Ahmed H. Bakheit, Hany W. Darwish, Hatem A. Abuelizz, Adnan A. Kadi
Publikováno v:
RSC Advances. 10:23930-23930
Correction for ‘In silico and in vitro metabolism of ribociclib: a mass spectrometric approach to bioactivation pathway elucidation and metabolite profiling’ by Thamer A. Alsubi et al., RSC Adv., 2020, 10, 22668–22683, DOI: 10.1039/D0RA01624A.