Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Mitnaul, Lyndon J."'
Autor:
Surakka, Ida, Fritsche, Lars, Zhou, Wei, Backman, Joshua, Kosmicki, Jack A., Lu, Haocheng, Brumpton, Ben Michael, Nielsen, Jonas B., Gabrielsen, Maiken Elvestad, Skogholt, Anne Heidi, Wolford, Brooke N., Graham, Sarah E., Chen, Y. Eugene, Lee, Seunggeun, Kang, Hyun Min, Langhammer, Arnulf, Forsmo, Siri, Åsvold, Bjørn Olav, Styrkarsdottir, Unnur, Holm, Hilma, Gudbjartsson, Daniel F., Stefansson, Kari, Baras, Aris, Bai, Xiaodong, Balasubramanian, Suganthi, Barnard, Leland, Blumenfeld, Andrew, Cantor, Michael, Coppola, Giovanni, Economides, Aris, Eom, Gisu, Habegger, Lukas, Hahn, Young, Hawes, Alicia, Jones, Marcus B., Khalid, Shareef, Lotta, Luca A., Maxwell, Evan K., Mitnaul, Lyndon J., Overton, John D., Reid, Jeffrey G., Ferreira, Manuel Allen Revez, Salerno, William, Sharma, Deepika, Shuldiner, Alan R., Staples, Jeffrey C., Yadav, Ashish, Abecasis, Goncalo R., Hveem, Kristian, Willer, Cristen J.
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
11:4093
Nature Communications, Vol 11, Iss 1, Pp 1-8 (2020)
11:4093
A major challenge in genetic association studies is that most associated variants fall in the non-coding part of the human genome. We searched for variants associated with bone mineral density (BMD) after enriching the discovery cohort for loss-of-fu
Autor:
Shah, Sonia, Henry, Albert, Roselli, Carolina, Lin, Honghuang, Sveinbjornsson, Gardar, Fatemifar, Ghazaleh, Hedman, Asa K, Wilk, Jemma B, Morley, Michael P, Chaffin, Mark D, Helgadottir, Anna, Verweij, Niek, Dehghan, Abbas, Almgren, Peter, Andersson, Charlotte, Aragam, Krishna G, Arnlov, Johan, Backman, Joshua D, Biggs, Mary L, Bloom, Heather L, Brandimarto, Jeffrey, Brown, Michael R, Buckbinder, Leonard, Carey, David J, Chasman, Daniel I, Chen, Xing, Chen, Xu, Chung, Jonathan, Chutkow, William, Cook, James P, Delgado, Graciela E, Denaxas, Spiros, Doney, Alexander S, Doerr, Marcus, Dudley, Samuel C, Dunn, Michael E, Engstrom, Gunnar, Esko, Tonu, Felix, Stephan B, Finan, Chris, Ford, Ian, Ghanbari, Mohsen, Ghasemi, Sahar, Giedraitis, Vilmantas, Giulianini, Franco, Gottdiener, John S, Gross, Stefan, Gudbjartsson, Daniel F, Gutmann, Rebecca, Haggerty, Christopher M, van der Harst, Pim, Hyde, Craig L, Ingelsson, Erik, Jukema, J Wouter, Kavousi, Maryam, Khaw, Kay-Tee, Kleber, Marcus E, Kober, Lars, Koekemoer, Andrea, Langenberg, Claudia, Lind, Lars, Lindgren, Cecilia M, London, Barry, Lotta, Luca A, Lovering, Ruth C, Luan, Jian'an, Magnusson, Patrik, Mahajan, Anubha, Margulies, Kenneth B, Maerz, Winfried, Melander, Olle, Mordi, Ify R, Morgan, Thomas, Morris, Andrew D, Morris, Andrew P, Morrison, Alanna C, Nagle, Michael W, Nelson, Christopher P, Niessner, Alexander, Niiranen, Teemu, O'Donoghue, Michelle L, Owens, Anjali T, Palmer, Colin NA, Parry, Helen M, Perola, Markus, Portilla-Fernandez, Eliana, Psaty, Bruce M, Rice, Kenneth M, Ridker, Paul M, Romaine, Simon PR, Rotter, Jerome I, Salo, Perttu, Salomaa, Veikko, van Setten, Jessica, Shalaby, Alaa A, Smelser, Diane T, Smith, Nicholas L, Stender, Steen, Stott, David J, Svensson, Per, Tammesoo, Mari-Liis, Taylor, Kent D, Teder-Laving, Maris, Teumer, Alexander, Thorgeirsson, Gudmundur, Thorsteinsdottir, Unnur, Torp-Pedersen, Christian, Trompet, Stella, Tyl, Benoit, Uitterlinden, Andre G, Veluchamy, Abirami, Voelker, Uwe, Voors, Adriaan A, Wang, Xiaosong, Wareham, Nicholas J, Waterworth, Dawn, Weeke, Peter E, Weiss, Raul, Wiggins, Kerri L, Xing, Heming, Yerges-Armstrong, Laura M, Yu, Bing, Zannad, Faiez, Zhao, Jing Hua, Hemingway, Harry, Samani, Nilesh J, McMurray, John JV, Yang, Jian, Visscher, Peter M, Newton-Cheh, Christopher, Malarstig, Anders, Holm, Hilma, Lubitz, Steven A, Sattar, Naveed, Holmes, Michael V, Cappola, Thomas P, Asselbergs, Folkert W, Hingorani, Aroon D, Kuchenbaecker, Karoline, Ellinor, Patrick T, Lang, Chim C, Stefansson, Kari, Smith, J Gustav, Vasan, Ramachandran S, Swerdlow, Daniel I, Lumbers, R Thomas, Abecasis, Goncalo, Backman, Joshua, Bai, Xiaodong, Balasubramanian, Suganthi, Banerjee, Nilanjana, Baras, Aris, Barnard, Leland, Beechert, Christina, Blumenfeld, Andrew, Cantor, Michael, Chai, Yating, Coppola, Giovanni, Damask, Amy, Dewey, Frederick, Economides, Aris, Eom, Gisu, Forsythe, Caitlin, Fuller, Erin D, Gu, Zhenhua, Gurski, Lauren, Guzzardo, Paloma M, Habegger, Lukas, Hahn, Young, Hawes, Alicia, van Hout, Cristopher, Jones, Marcus B, Khalid, Shareef, Lattari, Michael, Li, Alexander, Lin, Nan, Liu, Daren, Lopez, Alexander, Manoochehri, Kia, Marchini, Jonathan, Marcketta, Anthony, Maxwell, Evan K, McCarthy, Shane, Mitnaul, Lyndon J, O'Dushlaine, Colm, Overton, John D, Padilla, Maria Sotiropoulos, Paulding, Charles, Penn, John, Pradhan, Manasi, Reid, Jeffrey G, Schleicher, Thomas D, Schurmann, Claudia, Shuldiner, Alan, Staples, Jeffrey C, Sun, Dylan, Toledo, Karina, Ulloa, Ricardo H, Widom, Louis, Wolf, Sarah E, Yadav, Ashish, Ye, Bin, Ctr, Regeneron Genetics
Publikováno v:
Nature Communications, 11(1). NATURE PUBLISHING GROUP
Nature Communications
Nature Communications, 11(1):163. Nature Publishing Group
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Shah, S, Henry, A, Roselli, C, Lin, H, Sveinbjörnsson, G, Fatemifar, G, Hedman, Å K, Wilk, J B, Morley, M P, Chaffin, M D, Helgadottir, A, Verweij, N, Dehghan, A, Almgren, P, Andersson, C, Aragam, K G, Ärnlöv, J, Backman, J D, Biggs, M L, Bloom, H L, Brandimarto, J, Brown, M R, Buckbinder, L, Carey, D J, Chasman, D I, Chen, X, Chen, X, Chung, J, Chutkow, W, Cook, J P, Delgado, G E, Denaxas, S, Doney, A S, Dörr, M, Dudley, S C, Dunn, M E, Engström, G, Esko, T, Felix, S B, Finan, C, Ford, I, Ghanbari, M, Ghasemi, S, Giedraitis, V, Giulianini, F, Gottdiener, J S, Gross, S, Guðbjartsson, D F, Gutmann, R, Haggerty, C M, van der Harst, P, Hyde, C L, Ingelsson, E, Jukema, J W, Kavousi, M, Khaw, K-T, Kleber, M E, Køber, L, Koekemoer, A, Langenberg, C, Lind, L, Lindgren, C M, London, B, Lotta, L A, Lovering, R C, Luan, J, Magnusson, P, Mahajan, A, Margulies, K B, März, W, Melander, O, Mordi, I R, Morgan, T, Morris, A D, Morris, A P, Morrison, A C, Nagle, M W, Nelson, C P, Niessner, A, Niiranen, T, O’Donoghue, M L, Owens, A T, Palmer, C N A, Parry, H M, Perola, M, Portilla-Fernandez, E, Psaty, B M, Abecasis, G, Backman, J, Bai, X, Balasubramanian, S, Banerjee, N, Baras, A, Barnard, L, Beechert, C, Blumenfeld, A, Cantor, M, Chai, Y, Coppola, G, Damask, A, Dewey, F, Economides, A, Eom, G, Forsythe, C, Fuller, E D, Gu, Z, Gurski, L, Guzzardo, P M, Habegger, L, Hahn, Y, Hawes, A, van Hout, C, Jones, M B, Khalid, S, Lattari, M, Li, A, Lin, N, Liu, D, Lopez, A, Manoochehri, K, Marchini, J, Marcketta, A, Maxwell, E K, McCarthy, S, Mitnaul, L J, O’Dushlaine, C, Overton, J D, Padilla, M S, Paulding, C, Penn, J, Pradhan, M, Reid, J G, Schleicher, T D, Schurmann, C, Shuldiner, A, Staples, J C, Sun, D, Toledo, K, Ulloa, R H, Widom, L, Wolf, S E, Yadav, A, Ye, B, Rice, K M, Ridker, P M, Romaine, S P R, Rotter, J I, Salo, P, Salomaa, V, van Setten, J, Shalaby, A A, Smelser, D T, Smith, N L, Stender, S, Stott, D J, Svensson, P, Tammesoo, M-L, Taylor, K D, Teder-Laving, M, Teumer, A, Thorgeirsson, G, Thorsteinsdottir, U, Torp-Pedersen, C, Trompet, S, Tyl, B, Uitterlinden, A G, Veluchamy, A, Völker, U, Voors, A A, Wang, X, Wareham, N J, Waterworth, D, Weeke, P E, Weiss, R, Wiggins, K L, Xing, H, Yerges-Armstrong, L M, Yu, B, Zannad, F, Zhao, J H, Hemingway, H, Samani, N J, McMurray, J J V, Yang, J, Visscher, P M, Newton-Cheh, C, Malarstig, A, Holm, H, Lubitz, S A, Sattar, N, Holmes, M V, Cappola, T P, Asselbergs, F W, Hingorani, A D, Kuchenbaecker, K, Ellinor, P T, Lang, C C, Stefansson, K, Smith, J G, Vasan, R S, Swerdlow, D I & Lumbers, R T 2020, ' Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure ', Nature Communications, vol. 11, no. 1, 163 . https://doi.org/10.1038/s41467-019-13690-5
2020, ' Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure ', Nature Communications, vol. 11, no. 1, pp. 163 . https://doi.org/10.1038/s41467-019-13690-5
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.163. ⟨10.1038/s41467-019-13690-5⟩
Shah, S, Henry, A, Roselli, C, Lin, H, Sveinbjörnsson, G, Fatemifar, G, Hedman, Å K, Wilk, J B, Morley, M P, Chaffin, M D, Helgadottir, A, Verweij, N, Dehghan, A, Almgren, P, Andersson, C, Aragam, K G, Ärnlöv, J, Backman, J D, Biggs, M L, Bloom, H L, Brandimarto, J, Brown, M R, Buckbinder, L, Carey, D J, Chasman, D I, Chen, X, Chen, X, Chung, J, Chutkow, W, Cook, J P, Delgado, G E, Denaxas, S, Doney, A S, Dörr, M, Dudley, S C, Dunn, M E, Engström, G, Esko, T, Felix, S B, Finan, C, Ford, I, Ghanbari, M, Ghasemi, S, Morris, A P, Morris, A D, Nelson, C P, Smith, N L, Zhao, J H, Yang, J & Holmes, M V 2020, ' Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure ', Nature Communications, vol. 11, no. 1, pp. 163 . https://doi.org/10.1038/s41467-019-13690-5
Shah, S, Henry, A, Roselli, C, Lin, H, Sveinbjörnsson, G, Fatemifar, G, Hedman, Å K, Wilk, J B, Morley, M P, Chaffin, M D, Helgadottir, A, Verweij, N, Dehghan, A, Almgren, P, Andersson, C, Aragam, K G, Ärnlöv, J, Backman, J D, Biggs, M L, Bloom, H L, Brandimarto, J, Brown, M R, Buckbinder, L, Carey, D J, Chasman, D I, Chen, X, Chen, X, Chung, J, Chutkow, W, Cook, J P, Delgado, G E, Denaxas, S, Doney, A S, Dörr, M, Dudley, S C, Dunn, M E, Engström, G, Esko, T, Felix, S B, Finan, C, Ford, I, Ghanbari, M, Ghasemi, S, Giedraitis, V, Giulianini, F, Køber, L, Regeneron Genetics Center, Stender, S, Torp-Pedersen, C, Weeke, P E, Vasan, R S, Swerdlow, D I & Lumbers, R T 2020, ' Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure ', Nature Communications, vol. 11, 163 . https://doi.org/10.1038/s41467-019-13690-5
Nature Communications
Nature Communications, 11(1):163. Nature Publishing Group
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Shah, S, Henry, A, Roselli, C, Lin, H, Sveinbjörnsson, G, Fatemifar, G, Hedman, Å K, Wilk, J B, Morley, M P, Chaffin, M D, Helgadottir, A, Verweij, N, Dehghan, A, Almgren, P, Andersson, C, Aragam, K G, Ärnlöv, J, Backman, J D, Biggs, M L, Bloom, H L, Brandimarto, J, Brown, M R, Buckbinder, L, Carey, D J, Chasman, D I, Chen, X, Chen, X, Chung, J, Chutkow, W, Cook, J P, Delgado, G E, Denaxas, S, Doney, A S, Dörr, M, Dudley, S C, Dunn, M E, Engström, G, Esko, T, Felix, S B, Finan, C, Ford, I, Ghanbari, M, Ghasemi, S, Giedraitis, V, Giulianini, F, Gottdiener, J S, Gross, S, Guðbjartsson, D F, Gutmann, R, Haggerty, C M, van der Harst, P, Hyde, C L, Ingelsson, E, Jukema, J W, Kavousi, M, Khaw, K-T, Kleber, M E, Køber, L, Koekemoer, A, Langenberg, C, Lind, L, Lindgren, C M, London, B, Lotta, L A, Lovering, R C, Luan, J, Magnusson, P, Mahajan, A, Margulies, K B, März, W, Melander, O, Mordi, I R, Morgan, T, Morris, A D, Morris, A P, Morrison, A C, Nagle, M W, Nelson, C P, Niessner, A, Niiranen, T, O’Donoghue, M L, Owens, A T, Palmer, C N A, Parry, H M, Perola, M, Portilla-Fernandez, E, Psaty, B M, Abecasis, G, Backman, J, Bai, X, Balasubramanian, S, Banerjee, N, Baras, A, Barnard, L, Beechert, C, Blumenfeld, A, Cantor, M, Chai, Y, Coppola, G, Damask, A, Dewey, F, Economides, A, Eom, G, Forsythe, C, Fuller, E D, Gu, Z, Gurski, L, Guzzardo, P M, Habegger, L, Hahn, Y, Hawes, A, van Hout, C, Jones, M B, Khalid, S, Lattari, M, Li, A, Lin, N, Liu, D, Lopez, A, Manoochehri, K, Marchini, J, Marcketta, A, Maxwell, E K, McCarthy, S, Mitnaul, L J, O’Dushlaine, C, Overton, J D, Padilla, M S, Paulding, C, Penn, J, Pradhan, M, Reid, J G, Schleicher, T D, Schurmann, C, Shuldiner, A, Staples, J C, Sun, D, Toledo, K, Ulloa, R H, Widom, L, Wolf, S E, Yadav, A, Ye, B, Rice, K M, Ridker, P M, Romaine, S P R, Rotter, J I, Salo, P, Salomaa, V, van Setten, J, Shalaby, A A, Smelser, D T, Smith, N L, Stender, S, Stott, D J, Svensson, P, Tammesoo, M-L, Taylor, K D, Teder-Laving, M, Teumer, A, Thorgeirsson, G, Thorsteinsdottir, U, Torp-Pedersen, C, Trompet, S, Tyl, B, Uitterlinden, A G, Veluchamy, A, Völker, U, Voors, A A, Wang, X, Wareham, N J, Waterworth, D, Weeke, P E, Weiss, R, Wiggins, K L, Xing, H, Yerges-Armstrong, L M, Yu, B, Zannad, F, Zhao, J H, Hemingway, H, Samani, N J, McMurray, J J V, Yang, J, Visscher, P M, Newton-Cheh, C, Malarstig, A, Holm, H, Lubitz, S A, Sattar, N, Holmes, M V, Cappola, T P, Asselbergs, F W, Hingorani, A D, Kuchenbaecker, K, Ellinor, P T, Lang, C C, Stefansson, K, Smith, J G, Vasan, R S, Swerdlow, D I & Lumbers, R T 2020, ' Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure ', Nature Communications, vol. 11, no. 1, 163 . https://doi.org/10.1038/s41467-019-13690-5
2020, ' Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure ', Nature Communications, vol. 11, no. 1, pp. 163 . https://doi.org/10.1038/s41467-019-13690-5
Nature Communications, Nature Publishing Group, 2020, 11 (1), pp.163. ⟨10.1038/s41467-019-13690-5⟩
Shah, S, Henry, A, Roselli, C, Lin, H, Sveinbjörnsson, G, Fatemifar, G, Hedman, Å K, Wilk, J B, Morley, M P, Chaffin, M D, Helgadottir, A, Verweij, N, Dehghan, A, Almgren, P, Andersson, C, Aragam, K G, Ärnlöv, J, Backman, J D, Biggs, M L, Bloom, H L, Brandimarto, J, Brown, M R, Buckbinder, L, Carey, D J, Chasman, D I, Chen, X, Chen, X, Chung, J, Chutkow, W, Cook, J P, Delgado, G E, Denaxas, S, Doney, A S, Dörr, M, Dudley, S C, Dunn, M E, Engström, G, Esko, T, Felix, S B, Finan, C, Ford, I, Ghanbari, M, Ghasemi, S, Morris, A P, Morris, A D, Nelson, C P, Smith, N L, Zhao, J H, Yang, J & Holmes, M V 2020, ' Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure ', Nature Communications, vol. 11, no. 1, pp. 163 . https://doi.org/10.1038/s41467-019-13690-5
Shah, S, Henry, A, Roselli, C, Lin, H, Sveinbjörnsson, G, Fatemifar, G, Hedman, Å K, Wilk, J B, Morley, M P, Chaffin, M D, Helgadottir, A, Verweij, N, Dehghan, A, Almgren, P, Andersson, C, Aragam, K G, Ärnlöv, J, Backman, J D, Biggs, M L, Bloom, H L, Brandimarto, J, Brown, M R, Buckbinder, L, Carey, D J, Chasman, D I, Chen, X, Chen, X, Chung, J, Chutkow, W, Cook, J P, Delgado, G E, Denaxas, S, Doney, A S, Dörr, M, Dudley, S C, Dunn, M E, Engström, G, Esko, T, Felix, S B, Finan, C, Ford, I, Ghanbari, M, Ghasemi, S, Giedraitis, V, Giulianini, F, Køber, L, Regeneron Genetics Center, Stender, S, Torp-Pedersen, C, Weeke, P E, Vasan, R S, Swerdlow, D I & Lumbers, R T 2020, ' Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure ', Nature Communications, vol. 11, 163 . https://doi.org/10.1038/s41467-019-13690-5
Publisher's version (útgefin grein)
Heart failure (HF) is a leading cause of morbidity and mortality worldwide. A small proportion of HF cases are attributable to monogenic cardiomyopathies and existing genome-wide association studies (GWAS) ha
Heart failure (HF) is a leading cause of morbidity and mortality worldwide. A small proportion of HF cases are attributable to monogenic cardiomyopathies and existing genome-wide association studies (GWAS) ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a894b6e7f703eee196676f48718af1b7
https://doi.org/10.1038/s41467-019-13690-5
https://doi.org/10.1038/s41467-019-13690-5