Zobrazeno 1 - 10
of 14
pro vyhledávání: '"David G. Hoel"'
Autor:
Tomas Radivoyevitch, David G. Hoel
Publikováno v:
Mathematical Biosciences. 162:85-101
Formation of the BCR–ABL chromosomal translocation t (9;22)( q 34; q 11) is essential to the genesis of chronic myeloid leukemia (CML). An interest in the dose-response of radiation induced CML therefore leads naturally to an interest in the dose-r
Publikováno v:
Mathematical Biosciences. 149:107-136
When ionizing radiation strikes a cell it induces DNA double strand breaks (DSBs). Subsequently, some of the DSBs misrejoin and thus cause alterations in the size distribution of the DNA fragments. We derive a system of non-linear integro-differentia
Autor:
David G. Hoel, Gerald R. Chase
Publikováno v:
Biometrika. 62:329-334
SUMMARY The effect of small errors of dilution is shown to be sizeable when serial dilutions are required to estimate particle concentrations. Optimal dilution designs are given. The error effect and optimal design are also investigated for ratios of
Publikováno v:
Biometrika. 62:195-200
We examine results produced by a new likelihood stopping rule for terminating clinical trials, designed to choose the better of two competing dichotomous treatments, or to decide that they are equal. A method for adaptive assignment is also discussed
Autor:
Kenny S. Crump, David G. Hoel
Publikováno v:
Biometrika. 61:237-252
SUMMARY A number of mathematical models for cell populations in which mutations are occurring are studied and compared by viewing the models as filtered Poisson processes. Based upon these models, a statistical analysis is given of the mutant accumul
Autor:
David G. Hoel
Publikováno v:
Biometrika. 55:387-391
SUMMARY This paper is concerned with the application of several closed sequential procedures to the testing of an exponential parameter. In particular, the procedures of Armitage (1957), Schneiderman & Armitage (1962a,b) and Anderson (1960) are consi
Publikováno v:
Biometrika. 57:421-430
SUMMARY Answers to questions concerning adequate sample size in a one-way analysis of variance situation depend on such things as the number of categories to be compared, the levels of risk an experimenter is willing to assume and some knowledge of t
Publikováno v:
Biometrika. 59:317-322
SUMMARY In an earlier paper Sobel & Weiss (1970) examined two sampling schemes for choosing the binomial population with the larger probability of success. The two sequential allocation procedures were discussed in the light of their ability to reach
Publikováno v:
Biometrika. 57:573-577
Autor:
Amy H. Racine-Poon, David G. Hoel
Publikováno v:
Biometrics. 40:1151
SUMMARY A nonparametric estimator for the survival function, accommodating censored survival times and uncertainty in the assignment of cause of death, is proposed. For example, in a carcinogenicity experiment the data on each animal may consist of a