Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Brian O'Connell"'
Autor:
Lorena Baccaglini, Hilda Oweisy, A.T.M. Shamsul Hoque, Brian O'Connell, Virginia R. Braddon, Bruce J. Baum, Di Sun, Anne C. O'Connell, Laurie L. Herscher, Daniel R. Kenshalo, Philip C. Fox, Christine Delporte
Publikováno v:
Cancer gene therapy, 6 (6
Scopus-Elsevier
Scopus-Elsevier
This study evaluated the safety and efficacy of a single administration of a recombinant adenovirus encoding human aquaporin-1 (AdhAQP1) to the parotid glands of adult rhesus monkeys. In anticipation of possible clinical use of this virus to correct
Publikováno v:
Human Gene Therapy. 7:1085-1093
Although replication-deficient adenoviruses can efficiently transfer genes to the salivary glands, the current vectors precipitate an immediate, transient decrease in salivary function. To study the cause of this salivary hypofunction, 10(6)-10(10) p
Autor:
Philip C. Fox, Andrea Mastrangeli, Brian O'Connell, Ronald G. Crystal, W. Aladib, Bruce J. Baum
Publikováno v:
The American journal of physiology. 266(6 Pt 1)
Gene transfer to the salivary glands holds the potential for the therapy of salivary gland disorders and for delivery of therapeutic proteins to the mouth and upper gastrointestinal tract. Administration of the recombinant adenovirus vectors Ad.RSV b