Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Ena Wang"'
Autor:
Wouter Hendrickx, Peter J. K. Kuppen, Raghvendra Mall, Francesco M. Marincola, Gabriele Zoppoli, Ena Wang, Darawan Rinchai, François Bertucci, Julie Decock, Lucia Gemma Delogu, Josue Samayoa, Jessica Roelands, Tolga Turan, Pascal Finetti, Kyle Halliwill, Giuseppe Curigliano, Davide Bedognetti, Lance D. Miller, Alberto Ballestrero, Jérôme Galon, Mohamad Saad, Michele Ceccarelli, Lotfi Chouchane
Publikováno v:
Journal for ImmunoTherapy of Cancer, 8(1). BMJ PUBLISHING GROUP
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer, 2019, 8 (1), pp.e000617. ⟨10.1136/jitc-2020-000617⟩
Journal for Immunotherapy of Cancer, BMJ Publishing Group 2019, 8 (1), pp.e000617. ⟨10.1136/jitc-2020-000617⟩
Journal for ImmunoTherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer, 2019, 8 (1), pp.e000617. ⟨10.1136/jitc-2020-000617⟩
Journal for Immunotherapy of Cancer, BMJ Publishing Group 2019, 8 (1), pp.e000617. ⟨10.1136/jitc-2020-000617⟩
Journal for ImmunoTherapy of Cancer
BackgroundAn immune active cancer phenotype typified by a T helper 1 (Th-1) immune response has been associated with increased responsiveness to immunotherapy and favorable prognosis in some but not all cancer types. The reason of this differential p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54b3a13c708e237bd5b3181cab96edf6
http://hdl.handle.net/11577/3352619
http://hdl.handle.net/11577/3352619
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2055
It has been almost two decades since we first proposed the use of minimally invasive serial biopsies to dissect the biology underlining cancer immune responsiveness (CIR) by looking for predictors of response, understanding mechanisms of action (MOA)
Autor:
Willem W. Overwijk, Patrick Hwu, Francesco M. Marincola, Geok Choo Sim, Caitlin Creasy, Laszlo Radvanyi, Chengwen Liu, Elizabeth A. Grimm, Hui Liu, Zhimin Dai, Ena Wang, Jason Roszik
Publikováno v:
Cancer Immunology Research. 4:983-994
Clinical responses to high-dose IL2 therapy are limited due to selective expansion of CD4+CD25+Foxp3+ T-regulatory cells (Treg), especially ICOS+ Tregs, rather than natural killer (NK) cells and effector T cells. These ICOS+ Tregs are highly suppress
Autor:
Valentina Mattei, Ramzi Temanni, Rebecca Mathew, Davide Bedognetti, Lee Silcock, Barbara Seliger, Rashid Al-Ali, Ena Wang, Francesca Lessi, Sara Tomei, Puthen V. Jithesh, Hakeem Almabrazi, Francesco M. Marincola, Muna Al-Hashmi, Nicola James, Younes Mokrab
Publikováno v:
Journal of Translational Medicine
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-7 (2019)
Journal of Translational Medicine, Vol 17, Iss 1, Pp 1-7 (2019)
Background Monoallelic expression (MAE) is a frequent genomic phenomenon in normal tissues, however its role in cancer is yet to be fully understood. MAE is defined as the expression of a gene that is restricted to one allele in the presence of a dip
Autor:
Adi Reches, Simon Jasinski-Bergner, Sven Wach, Barbara Seliger, Arndt Hartmann, Ena Wang, Christine Stoehr, Francesco M. Marincola, Ofer Mandelboim, Chiara Massa, Juliane Braun, Bernd Wullich, Stefan Huettelmaier, Evamaria Gonschorek, Verena Spath
Publikováno v:
Oncotarget
The non-classical human leukocyte antigen G (HLA-G) is expressed at a high frequency in renal cell carcinoma (RCC) and is associated with a higher tumor grade and a poor clinical outcome. This might be caused by the HLA-G-mediated inhibition of the c
Autor:
Daniel J. Powell, Lana E. Kandalaft, Renee Frank, Thomas Garrabrant, Priyanka Duttagupta, Hongzhe Li, Denarda Dangaj, Davide Bedognetti, Ian S. Hagemann, George Coukos, Emese Zsiros, Ena Wang, Michael Feldman, Janos L. Tanyi, Francesco M. Marincola, Carl H. June, Lin Zhang, Bruce L. Levine
Publikováno v:
Clinical Cancer Research, vol. 21, no. 12, pp. 2840-2850
Purpose: Chemokines are implicated in T-cell trafficking. We mapped the chemokine landscape in advanced stage ovarian cancer and characterized the expression of cognate receptors in autologous dendritic cell (DC)–vaccine primed T cells in the conte
Autor:
Douglas C. Palmer, John S. Tsang, Suresh Cuddapah, Christopher A. Klebanoff, Ena Wang, Joseph G. Crompton, Yun Ji, Manikandan Narayanan, Luca Gattinoni, Rahul Roychoudhuri, Keji Zhao, Francesco M. Marincola, Shashank J. Patel, Madhusudhanan Sukumar, Weiqun Peng, Wenjing Yang, Nicholas P. Restifo
Publikováno v:
Cellular and Molecular Immunology
To better elucidate epigenetic mechanisms that correlate with the dynamic gene expression program observed upon T-cell differentiation, we investigated the genomic landscape of histone modifications in naive and memory CD8(+) T cells. Using a ChIP-Se
Autor:
Francesco M. Marincola, David F. Stroncek, Ena Wang, Jin Ping, Yingdong Zhao, Luciano Castiello, Lauren V. Wood, Marianna Sabatino, Jiaqiang Ren, Barbara Tumaini, Raj K. Puri
Publikováno v:
Molecular Therapy. 21(2):476-484
Cell-based immunotherapies are among the most promising approaches for developing effective and targeted immune response. However, their clinical usefulness and the evaluation of their efficacy rely heavily on complex quality control assessment. Ther
Autor:
Michael A. Black, Sandra Demaria, Ashok K. Pullikuth, Angela Tatiana Alistar, Ena Wang, Julia Chifman, Jeff A Chou, Francesco M. Marincola, Cristin G. Print, Eran R. Andrechek, Xiaobo Zhou, Thomas C. Putti, Wouter Hendrickx, Davide Bedognetti, Lance D. Miller, Jonathan P. Rennhack
The abundance and functional orientation of tumor-infiltrating lymphocytes in breast cancer is associated with distant metastasis-free survival, yet how this association is influenced by tumor phenotypic heterogeneity is poorly understood. Here, a bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa1784e8eed1d0e64aa28a674919819
https://europepmc.org/articles/PMC4930674/
https://europepmc.org/articles/PMC4930674/
Autor:
Robert B. Nussenblatt, Ena Wang, Huizhi Zhou, Foo Cheung, John S. Tsang, Rongye Shi, Yuri Kotliarov, Matthew J. Olnes, Jinguo Chen, Angelique Biancotto
Publikováno v:
Scientific Reports
Corticosteroids have been used for decades to modulate inflammation therapeutically, yet there is a paucity of data on their effects in humans. We examined the changes in cellular and molecular immune system parameters, or “immunome”, in healthy