Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Youyi Zhang"'
Autor:
Lixiang Xue, Baoling Zhu, Kai Xiong, Dandan Shi, Li Chen, Youyi Zhang, Rongrong Sun, Zijian Li, Yan Sun
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182668 (2017)
PLoS ONE
PLoS ONE
Pathological cardiac hypertrophy used to be elucidated by biomechanical, stretch-sensitive or neurohumoral mechanisms. However, a series of hints have indicated that hypertrophy process simulates senescence program. However, further evidence need to
Autor:
Youyi Zhang, Zhijie Wang, Gencheng Han, Chunmei Hou, X Liu, Ning Ma, Yixue Li, B. Shen, Renxi Wang, Tianxiao Wang, Xizhang Wang, G Zhu, Guojiang Chen, He Xiao
Publikováno v:
Clinical and experimental immunology. 186(2)
Summary Interleukin (IL)-12 family cytokines play critical roles in autoimmune diseases. Our previous study has shown that IL-23p19 and Epstein–Barr virus-induced 3 (Ebi3) form a new IL-12 family heterodimer, IL-23p19/Ebi3, termed IL-39, and knock-
Autor:
Youyi Zhang, Jiaqing Hao, Yin Li, J Wang, Xiao Song, H Tang, Chengli Guo, Q He, Yong Wang, Yuxin Yin, Qin Xiaoxiao
Publikováno v:
Oncogene. 36(11)
The biological function of MAGEC2, a cancer/testis antigen highly expressed in various cancers, remains largely unknown. Here we demonstrate that expression of MAGEC2 induces rounded morphology and amoeboid-like movement of tumor cells in vitro and p
Autor:
Zijian Li, Qian Yin, Youyi Zhang, Xiaopu Zheng, Haiyan Lu, Zhizhen Lv, Chengzhi Yang, Xiaohui Zheng, Jimin Wu
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152005 (2016)
PLoS ONE
PLoS ONE
β-adrenergic receptors (β-ARs) play an important role in cardiac remodeling, which is the key pathological process in various heart diseases and leads to heart failure. However, the regulation of β-AR expression in remodeling hearts is still uncle
Autor:
Xin Cong, Zhi-Gang Cai, Youyi Zhang, Guang-Yan Yu, Li-Ling Wu, Xiaofeng Shan, Hui Xu, N.Y. Yang
Publikováno v:
Journal of dental research. 94(10)
Intraglandular injection of botulinum toxin type A (BoNT/A) is an effective treatment for sialorrhea. Despite numerous experimental and clinical studies on inhibition of saliva section by BoNT/A, the proteolysis of synaptosomal-associated protein 25
Publikováno v:
Acta Pharmacologica Sinica. 26:77-84
Aim: To investigate the α 1B -adrenoceptor (α 1B -AR)-mediated cAMP response and underlying mechanisms in HEK293 cells. Methods: Full-length cDNA encoding α 1B -AR was transfected into HEK293 cells using the calcium phosphate precipitation method,
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 31:602-607
1. Vascular adrenoceptors play an important role in vascular physiology and pathophysiology, such as hypertension, atherosclerosis and restenosis after angioplasty. To define the changes in the ene expression in vascular smooth muscle cells in respon
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 30:827-832
1. In the present study, the effects of losartan on myocardial gene expression changes following cardiac hypertrophy were investigated. 2. Male Wistar rats were randomized to receive 5 or 30 mg/kg per day losartan (i.p.) 1 day after suprarenal abdomi
Publikováno v:
Cellular and Molecular Life Sciences (CMLS). 60:2200-2209
Catecholamines play an important role in the development of cardiac hypertrophy. To observe cardiomyocyte-specific gene expression changes induced by catecholamines in vivo, left ventricular cardiomyocytes were isolated from male Sprague-Dawley rats
Agonist-induced down-regulation of α1B-adrenergic receptor in HEK293 cells transfected with α1B cDNA
Publikováno v:
Science in China Series C: Life Sciences. 41:309-314
HEK293 cells stably expressing hamster alpha(1B)-adrenergic receptor (alpha(1B)-AR) were used to observe the effect of nonepinephrine (NE) on alpha(1B)-AR gene expression. Radioligand binding assys and RNase protection assays were used to determine a