Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Yong J. Lee"'
Publikováno v:
Cell Death & Differentiation. 9:448-456
We previously reported that overexpression of HSP25 delayed cell growth, increased the level of p21(waf), reduced the levels of cyclin D1, cyclin A and cdc2, and induced radioresistance in L929 cells. In this study, we demonstrated that HSP25 induced
Publikováno v:
Cell Death & Differentiation. 8:44-50
Cyclin D1 expression is co-regulated by growth factor and cell adhesion signaling. Cell adhesion to the extracellular matrix activates focal adhesion kinase (FAK), which is essential for cyclin D1 expression. Upon the loss of cell adhesion, cyclin D1
Autor:
Yong J. Lee, Peter M. Corry
Publikováno v:
Molecular and Cellular Biochemistry. 202:1-8
Although the synthesis of angiogenic factors in hypoxic regions of solid tumors is recognized as one of the critical steps in tumor growth and metastasis, the signal transduction pathway involved in hypoxic induction of basic fibroblast growth factor
Autor:
Peter M. Corry, Yong J. Lee
Publikováno v:
Journal of Biological Chemistry. 273:29857-29863
In previous reports we demonstrated that glucose deprivation induces metabolic oxidative stress in drug-resistant human breast carcinoma MCF-7/ADR cells (Lee, Y. J., Galoforo, S. S., Berns, c. M., Chen, J. C., Davis, B. H., Swim, J. E., Corry, P. M.,
Thermotolerance expression in mitotic CHO cells without increased translation of heat shock proteins
Autor:
Michael J. Borrelli, Diane M. Stafford, Peter M. Corry, Yong J. Lee, Lisa A. Karczewski, Cynthia M. Rausch
Publikováno v:
Journal of Cellular Physiology. 169:420-428
The objective of this study was to unequivocally demonstrate thermotolerance expression in mammalian cells in the absence of stress-induced synthesis of heat shock proteins (HSPs). Mitotic cells were selected as an experimental system since their gen
Autor:
Christine M. Berns, Eliezer Huberman, Robert V. Blackburn, Peter M. Corry, Sandra Galoforo, Yong J. Lee
Publikováno v:
Biochemical Pharmacology. 52:311-319
We investigated the effect of 1α-25-dihydroxyvitamin D 3 [1,25-(OH) 2 D 3 ] on the expression of the 28-kDa heat shock protein gene ( hsp28 ) and the protein kinase C beta gene ( PKC β) in the human myeloid HL-60 leukemic cell variant HL-525, which
Autor:
Peter M. Corry, Geza Erdos, Christine M. Berns, Yong J. Lee, Sandra Galoforo, Anjali K. Gupta, D. K. Ways
Publikováno v:
Journal of Biological Chemistry. 270:28790-28796
We studied the effect of ionizing radiation on the activation of the AP-1 transcription factors and the regulation of basic fibroblast growth factor (bFGF) gene expression in drug-sensitive human breast carcinoma (MCF-7) cells and its drug-resistant
Publikováno v:
Biochemical Pharmacology. 50:1149-1155
We studied the effect of isoquinolinesulfonamide derivatives (H-7, H-8, and HA 1004) on the expression of two heat shock genes ( αB - crystallin and hsp70 ) in NIH 3T3 and Swiss 3T3 cells after heat shock at 45° for 10 min. Western blots and northe
Autor:
Xinxin Song, Edward V. Prochownik, Douglas R. Spitz, Juong G. Rhee, Seog Young Kim, Yong J. Lee
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50423 (2012)
PLoS ONE
PLoS ONE
There are contradictory observations about the different radiosensitivities of cancer stem cells and cancer non-stem cells. To resolve these contradictory observations, we studied radiosensitivities by employing breast cancer stem cell (CSC)-like MDA
Autor:
Michael J. Borrelli, Geza Erdos, Christine M. Berns, Peter M. Corry, Yong J. Lee, Chang H. Ahn
Publikováno v:
Biochemical Pharmacology. 48:2057-2063
The effect of 1-(5-isoquinolinesulfonyl)-2-methylpiperazine (H-7), a potent protein kinase C (PKC) inhibitor, on the development of thermotolerance and expression of heat shock genes (HSP70 and HSP28) was investigated in human colon carcinoma HT-29 c