Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jonghwan Kim"'
Autor:
Bum Kyu Lee, Jiwoon Lee, Jonghwan Kim, Yu Jin Jang, Lucy LeBlanc, Samuel Beck, Catherine Rhee, Wenwen Shen, Mijeong Kim
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications
Nature Communications
Trophectoderm (TE) lineage development is pivotal for proper implantation, placentation, and healthy pregnancy. However, only a few TE-specific transcription factors (TFs) have been systematically characterized, hindering our understanding of the pro
Autor:
Mijeong Kim, Aparna V Kambhampati, Jonghwan Kim, Lucy LeBlanc, Nereida Ramirez, Albert J. Son
Publikováno v:
iScience
iScience, Vol 25, Iss 1, Pp 103541-(2022)
iScience, Vol 25, Iss 1, Pp 103541-(2022)
Summary Although cell density is known to affect numerous biological processes including gene expression and cell fate specification, mechanistic understanding of what factors link cell density to global gene regulation is lacking. Here, we reveal th
Autor:
Shannon M Dupont, Lucy LeBlanc, Andy C Yu, Davide Seruggia, Jonghwan Kim, Stuart H. Orkin, Aparna V Kambhampati, Byoung U Ryu, Mijeong Kim, Bum Kyu Lee
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
Approximately, 30% of embryonic stem cells (ESCs) die after exiting self-renewal, but regulators of this process are not well known. Yap1 is a Hippo pathway transcriptional effector that plays numerous roles in development and cancer. However, its fu
Autor:
Lucy LeBlanc, Jawon Song, Jonghwan Kim, Samuel Beck, Laurie Cannon, Catherine Rhee, Bum Kyu Lee
Publikováno v:
Nucleic Acids Research
CpG islands (CGIs) have long been implicated in the regulation of vertebrate gene expression. However, the involvement of CGIs in chromosomal architectures and associated gene expression regulations has not yet been thoroughly explored. By combining
Autor:
Siddharth Rode, Jonghwan Kim, Kevin Chin, Vishwanath R. Iyer, Likai Wang, Eun Esther Ko, Hong Qiao, Fan Zhang
Publikováno v:
BMC Genomics
BMC Genomics, Vol 18, Iss 1, Pp 1-13 (2017)
BMC Genomics, Vol 18, Iss 1, Pp 1-13 (2017)
Background Histone acetylation and deacetylation are essential for gene regulation and have been implicated in the regulation of plant hormone responses. Many studies have indicated the role of histone acetylation in ethylene signaling; however, few
Autor:
Martin Oti, Lucy LeBlanc, Partha Pratim Das, Davide Seruggia, Matthew C. Canver, Jose M. Polo, Rick Farouni, Michael J. Bullen, Luca Pinello, Dafne Campigli Di Giammartino, Effie Apostolou, Stuart H. Orkin, Jonghwan Kim, Christian M. Nefzger, Pratibha Tripathi, Yu Bo Yang Sun
Publikováno v:
Molecular Cell. 74:1148-1163.e7
Summary Self-renewal and pluripotency of the embryonic stem cell (ESC) state are established and maintained by multiple regulatory networks that comprise transcription factors and epigenetic regulators. While much has been learned regarding transcrip
Autor:
Andrew J. Woo, Huaiyong Chen, David W. Gludish, Arven H. Saunders, Joo-Hyeon Lee, Jonghwan Kim, Barry R. Stripp, Juliana Barrios, Rebecca R. Roach, Yuko Fujiwara, David A. Conner, Carla F. Kim
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 48:288-298
The regeneration of alveolar epithelial cells is a critical aspect of alveolar reorganization after lung injury. Although alveolar Type II (AT2) cells have been described as progenitor cells for alveolar epithelia, more remains to be understood about
Autor:
Jonghwan Kim, Vishwanath R. Iyer
Publikováno v:
Molecular and Cellular Biology. 24:8104-8112
The recruitment of TATA box-binding protein (TBP) to promoters is one of the rate-limiting steps during transcription initiation. However, the global importance of TBP recruitment in determining the absolute and changing levels of transcription acros
Autor:
Daehee Hwang, Michael R. Freeman, Jayoung Kim, Keith R. Solomon, Dolores Di Vizio, Steven K. Clinton, Jonghwan Kim, Minjung Kim, Kristine Pelton, Taek Kyun Kim, Tsonwin Hai
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 7, p e39448 (2012)
PLoS ONE, Vol 7, Iss 7, p e39448 (2012)
Elevated circulating cholesterol is a systemic risk factor for cardiovascular disease and metabolic syndrome, however the manner in which the normal prostate responds to variations in cholesterol levels is poorly understood. In this study we addresse
Publikováno v:
Blood. 118(13)
The molecular mechanisms underlying erythroid-specific gene regulation remain incompletely understood. Closely spaced binding sites for GATA, NF-E2/maf, and CACCC interacting transcription factors play functionally important roles in globin and other