Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Takeshi Iwaya"'
Autor:
Satoshi Nishizuka, Yuji Akiyama, Koki Otsuka, Masafumi Konosu, Takeshi Takahara, Masaru Mizuno, Genta Sawada, Kohei Kume, Fumitaka Endo, Suburu Amano, Akira Sasaki, Koshi Mimori, Takeshi Iwaya, Keisuke Koeda, Hiroyuki Nitta, Chie Ito, Yoshihiro Shioi
Publikováno v:
International journal of oncology. 50(2)
Tylosis is an inherited disorder characterized by abnormal palmoplantar skin thickening and a highly elevated risk of esophageal squamous cell carcinoma (ESCC). Analyses of tylosis in families have localized the responsible gene locus to a region of
Publikováno v:
Cancer Research. 79:1378-1378
Precise relapse prediction in cancer patients is urgently needed as conventional serum tumor markers do not predict relapse in a timely manner. Circulating tumor DNA (ctDNA) is a new class of quantitative biomarkers that reflect tumor burden. The ctD
Autor:
Satoshi Nishizuka, Koki Otsuka, Kiichi Aoki, Kazuyoshi Saito, Ken Sakata, Nobuhiro Sato, Yasushi Suzuki, Takeshi Iwaya, Chihaya Maesawa, Satoshi Ogasawara, Kaoru Ishida, Yusuke Kimura, Kenichiro Ikeda, Keisuke Koeda, Gen Tamura
Publikováno v:
Genes, Chromosomes and Cancer. 23:317-322
Frequent frameshift mutations of simple nucleotide repeats in the protein-encoding regions, as well as replication errors (RERs) at microsatellite loci, have recently been demonstrated in gastrointestinal tumors. These genetic instabilities have been
Mutations in the human homologue of theDrosophila patched gene in esophageal squamous cell carcinoma
Autor:
Kaoru Ishida, Gen Tamura, Chihaya Maesawa, Kiich Aoki, Nobuhiro Sato, Takeshi Iwaya, Satoshi Nishizuka, Kazuyoshi Saito, Yasushi Suzuki, Satoshi Ogasawara, Ikeda K, Ryoichi Satodate
Publikováno v:
Genes, Chromosomes and Cancer. 21:276-279
The human homologue (PTCH) of the Drosophila segment polarity gene patchedhas recently been identified as a tumor-suppressor gene for nevoid basal cell carcinoma syndrome and for sporadic basal cell carcinomas of the skin. We analyzed 30 esophageal s
Autor:
Takeshi Iwaya, Gen Tamura, Ken Sakata, Chihaya Maesawa, Kazuyoshi Saito, Satoshi Nishizuka, Yasushi Suzuki, Masanori Terashima, Ryoichi Satodate
Publikováno v:
Genes, Chromosomes and Cancer. 20:98-102
The FHIT (fragile histidine triad) gene has been isolated from the chromosome region 3p14.2, which includes the fragile site locus FRA3B and the breakpoint of the t(3;8) of familial renal carcinoma. FHIT has been suggested to be a candidate tumor sup
Autor:
Takeshi Iwaya, Ryoichi Satodate, Chihaya Maesawa, Yasushi Suzuki, Ken Sakata, Gen Tamura, Kazuyoshi Saito, Masanori Terashima, Satoshi Nishizuka
Publikováno v:
Genes, Chromosomes and Cancer. 18:318-321
During an allelotype analysis of differentiated adenocarcinoma of the stomach, we observed frequent loss of heterozygosity (LOH) on several chromosomes including the long arm of chromosome 21 (21q). Therefore, we analyzed DNA isolated from 45 tumors
Autor:
Takeshi Iwaya, Gen Tamura, Kazuyoshi Saito, M Terashima, Ryoichi Satodate, Satoshi Nishizuka, Ken Sakata, Yasushi Suzuki, Chihaya Maesawa
Publikováno v:
Japanese Journal of Cancer Research : Gann
We investigated the E (epithelial)‐cadherin gene for mutations and loss of heterozygosity (LOH) in 24 primary gastric carcinomas (12 differentiated and 12 undifferentiated types, including 3 signet‐ring cell carcinomas), as well as 4 gastric carc
Autor:
Akira Sasaki, Yoshihiro Shioi, Takeshi Iwaya, Kohei Kume, Chie Ito, Fumitaka Endo, Satoshi Nishizuka, Suburu Amano, Yuji Akiyama, Koshi Mimori
Publikováno v:
Cancer Research. 76:1162-1162
[Background] Tylosis is an autosomal dominant skin disorder that is associated with the early onset of esophageal squamous cell carcinoma (ESCC) in several families. The tylosis esophageal cancer (TOC) gene locus has been mapped to chromosome 17q25.1
Autor:
Yoshihiro Shioi, Fumitaka Endo, Akira Sasaki, Satoshi Nishizuka, Kohei Kume, Suburu Amano, Chie Ito, Yuji Akiyama, Takeshi Iwaya
Publikováno v:
Cancer Research. 76:1159-1159
[Background] Esophageal squamous cell carcinoma (ESCC) is one of the most malignant cancers. The molecular mechanism of ESCC development has not been fully elucidated. [Aim] The aim of this study is to identify responsible genes for ESCC development.
Publikováno v:
Cancer Research. 75:5460-5460
Peritonitis carcinomatosa (PC) is one of the most devastating states of digestive tract cancers and occurs at a substantial frequency even after curative removal of the primary lesions followed by adjuvant chemotherapy. Tumor cells involved in PC aft