Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Brett A. Neilan"'
Publikováno v:
Microbial Biotechnology
Microbial Biotechnology, Vol 13, Iss 5, Pp 1415-1427 (2020)
Microbial Biotechnology, Vol 13, Iss 5, Pp 1415-1427 (2020)
Summary Genome mining of Ascomycete sp. F53 (F53), a fungal endophyte of the traditional Chinese medicinal plant Taxus yunnanensis (Chinese yew), revealed 35 putative specialized metabolite biosynthesis gene clusters, one of which encodes a rarely se
Publikováno v:
Genome Biology and Evolution
Cyanobacteria are prolific producers of natural products, including polyketides and hybrid compounds thereof. Type III polyketide synthases (PKSs) are of particular interest, due to their wide substrate specificity and simple reaction mechanism, comp
Autor:
Alescia Cullen, Rabia Mazmouz, Sarah E. Ongley, Leanne A. Pearson, Brett A. Neilan, Tianzhe Liu, Angela H. Soeriyadi
Publikováno v:
Natural Product Reports. 36:1117-1136
Covering: up to 2018 Marine and freshwater cyanobacteria produce a variety of toxic compounds that pose a threat to the health of humans, livestock and natural ecosystems world-wide. Significant research efforts have been directed towards understandi
Publikováno v:
Applied and Environmental Microbiology. 87
Pseudoalteromonas species produce a diverse range of biologically active compounds, including those biosynthesized by nonribosomal peptide synthetases (NRPSs) and polyketide synthases (PKSs). Here, we report the biochemical and genomic analysis of Ps
Autor:
Jason N. Woodhouse, Russell Pickford, Paul M. D'Agostino, Rabia Mazmouz, Brett A. Neilan, Ian Jameson, Joao P.A. Pereyra
Publikováno v:
Toxicon. 138:68-77
The cyanobacterium Dolichospermum circinale (formerly Anabaena circinalis) is responsible for neurotoxic saxitoxin-producing blooms in Australia. Previous studies have reported distinct isolates of toxic D. circinale producing different saxitoxin ana
Autor:
Rabia Mazmouz, P. R. Puranik, Brett A. Neilan, Paul M. D'Agostino, Russell Pickford, Vivek S. Javalkote
Publikováno v:
Applied and Environmental Microbiology. 82:5951-5959
The mycosporine-like amino acids (MAAs) are a group of small molecules with a diverse ecological distribution among microorganisms. MAAs have a range of physiological functions, including protection against UV radiation, making them important from a
Autor:
Brett A. Neilan, Belinda C. Ferrari, Eden Zhang, Josie van Dorst, John A. Kalaitzis, Mark V. Brown, Nicole Benaud
Publikováno v:
FEMS Microbiology Ecology. 95
The severity of environmental conditions at Earth's frigid zones present attractive opportunities for microbial biomining due to their heightened potential as reservoirs for novel secondary metabolites. Arid soil microbiomes within the Antarctic and
Autor:
Paul M. D'Agostino, Russell Pickford, Susanna A. Wood, Brett A. Neilan, Alescia Cullen, Rabia Mazmouz
Publikováno v:
ACS chemical biology. 13(11)
The neurotoxin saxitoxin and related paralytic shellfish toxins are produced by multiple species of cyanobacteria and dinoflagellates. This study investigates the two saxitoxin-producing strains of Scytonema crispum, CAWBG524 and CAWBG72, isolated in
Autor:
Jason N. Woodhouse, Paul M. D'Agostino, A. Katharina Makower, Anna C. Y. Yeung, Brett A. Neilan, Melinda L. Micallef, Michelle C. Moffitt, Sarah E. Ongley
Publikováno v:
Environmental Microbiology Reports. 8:3-13
A common misconception persists that the genomes of toxic and non-toxic cyanobacterial strains are largely conserved with the exception of the presence or absence of the genes responsible for toxin production. Implementation of -omics era technologie
Publikováno v:
Marine and Freshwater Research. 71:701
The cyanobacterium Microcystis aeruginosa has been linked to toxic blooms worldwide. In addition to producing hepatotoxic microcystins, many strains are capable of synthesising a variety of biologically active compounds, including protease and phosph