Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Manal F. Abdelmalek"'
Autor:
Rohit Loomba, Manal F Abdelmalek, Matthew J Armstrong, Maximilian Jara, Mette Skalshøi Kjær, Niels Krarup, Eric Lawitz, Vlad Ratziu, Arun J Sanyal, Jörn M Schattenberg, Philip N Newsome
Publikováno v:
The Lancet Gastroenterology & Hepatology. 8:511-522
Autor:
Manal F. Abdelmalek, Arun J. Sanyal, Atsushi Nakajima, Brent A. Neuschwander-Tetri, Zachary D. Goodman, Eric J. Lawitz, Stephen A. Harrison, Ira M. Jacobson, Kento Imajo, Nadege Gunn, Dina Halegoua-DeMarzio, Takemi Akahane, Bradly Boone, Masayuki Yamaguchi, Arkendu Chatterjee, Giridhar S. Tirucherai, Diane E. Shevell, Shuyan Du, Edgar D. Charles, Rohit Loomba
Publikováno v:
Clinical Gastroenterology and Hepatology.
Autor:
Rohit Loomba, Arun J. Sanyal, Atsushi Nakajima, Brent A. Neuschwander-Tetri, Zachary D. Goodman, Stephen A. Harrison, Eric J. Lawitz, Nadege Gunn, Kento Imajo, Natarajan Ravendhran, Takemi Akahane, Bradly Boone, Masayuki Yamaguchi, Arkendu Chatterjee, Giridhar S. Tirucherai, Diane E. Shevell, Shuyan Du, Edgar D. Charles, Manal F. Abdelmalek
Publikováno v:
Clinical Gastroenterology and Hepatology.
Autor:
Quentin M. Anstee, Brent A. Neuschwander-Tetri, Vincent Wai-Sun Wong, Manal F. Abdelmalek, Gerardo Rodriguez-Araujo, Henrik Landgren, Grace S. Park, Pierre Bedossa, Naim Alkhouri, Frank Tacke, Arun J. Sanyal
Publikováno v:
Clinical Gastroenterology and Hepatology.
Autor:
Eric Lawitz, Manuel Romero-Gómez, Quentin M. Anstee, Stephen A. Harrison, Catherine Jia, Zobair M. Younossi, Chuhan Chung, Zachary Goodman, Robert P. Myers, Ryan S Huss, Michael Trauner, Vincent Wai-Sun Wong, Andrew J. Muir, Takeshi Okanoue, Jaime Bosch, D. Ding, Nezam H. Afdhal, Manal F. Abdelmalek, Ling Han, Arun J. Sanyal
Publikováno v:
Sanyal, Arun J; Anstee, Quentin M; Trauner, Michael; Lawitz, Eric J; Abdelmalek, Manal F; Ding, Dora; Han, Ling; Jia, Catherine; Huss, Ryan S; Chung, Chuhan; Wong, Vincent Wai-Sun; Okanoue, Takeshi; Romero-Gomez, Manuel; Muir, Andrew J; Afdhal, Nezam H; Bosch, Jaime; Goodman, Zachary; Harrison, Stephen A; Younossi, Zobair M and Myers, Robert P (2022). Cirrhosis Regression is Associated with Improved Clinical Outcomes in Patients with Nonalcoholic Steatohepatitis. Hepatology, 75(5), pp. 1235-1246. Wiley 10.1002/hep.32204
[Background and Aims] Surrogate endpoints that predict complications are necessary for assessment and approval of NASH therapies. We assessed associations between histologic and noninvasive tests (NITs) of fibrosis with liver‐related complications
Publikováno v:
Gastroenterology. 163:e10-e12
Autor:
Tianyi Chen, George Dalton, Seh-Hoon Oh, Raquel Maeso-Diaz, Kuo Du, Rachel A. Meyers, Cynthia Guy, Manal F. Abdelmalek, Ricardo Henao, Paolo Guarnieri, Steven S. Pullen, Simon Gregory, Joseph Locker, J. Mark Brown, Anna Mae Diehl
Publikováno v:
Cellular and molecular gastroenterology and hepatology.
Nonalcoholic steatohepatitis (NASH), a leading cause of cirrhosis, strongly associates with the Metabolic Syndrome (MetS), an insulin-resistant pro-inflammatory state that disrupts energy balance and promotes progressive liver degeneration. We aimed
Autor:
Danielle Brandman, Marie Boyle, Stuart McPherson, Mark L. Van Natta, Arun J. Sanyal, Kris Kowdley, Brent Neuschwander‐Tetri, Naga Chalasani, Manal F. Abdelmalek, Norah A. Terrault, Art McCullough, Ricki Bettencourt, Cyrielle Caussy, David E. Kleiner, Cynthia Behling, James Tonascia, Quentin M. Anstee, Rohit Loomba
Publikováno v:
Alimentary Pharmacology & Therapeutics. 56:182-183
Autor:
Stephen A Harrison, Manal F Abdelmalek, Guy Neff, Nadege Gunn, Cynthia D Guy, Naim Alkhouri, Mustafa R Bashir, Bradley Freilich, Anita Kohli, Arun Khazanchi, Muhammad Y Sheikh, Mark Leibowitz, Mary E Rinella, Mohammad S Siddiqui, Mark Kipnes, Sam E Moussa, Ziad H Younes, Meena Bansal, Seth J Baum, Brian Borg, Peter J Ruane, Paul J Thuluvath, Mildred Gottwald, Mujib Khan, Charles Chen, Liza Melchor-Khan, William Chang, Alex M DePaoli, Lei Ling, Hsiao D Lieu
Publikováno v:
The lancet. Gastroenterologyhepatology. 7(7)
Non-alcoholic steatohepatitis (NASH) is characterised by hepatic steatosis, inflammation, and injury, and is associated with an increased risk of liver transplantation and death. NASH affects more than 16 million people in the USA, and there is no ap
Autor:
Guadalupe Garcia-Tsao, Jaime Bosch, Zeid Kayali, Stephen A. Harrison, Manal F. Abdelmalek, Eric Lawitz, Sanjaya K. Satapathy, Marwan Ghabril, Mitchell L. Shiffman, Ziad H. Younes, Paul J. Thuluvath, Annalisa Berzigotti, Agustin Albillos, James M. Robinson, David T. Hagerty, Jean L. Chan, Arun J. Sanyal, M. Abdelmalek, K. Bhamidimarri, B. Borg, S. Caldwell, J. Fenkel, B. Freilich, M. Fuchs, M. Ghabril, R. Ghalib, S. Gonzalez, S. Gordon, B. Hameed, S. Harrison, Z. Kayali, N. Kemmer, K. Korenblat, M. Lai, C. Landis, E. Lawitz, W. Lee, S. Lidofsky, E. Mena, M. Noureddin, A. Paredes, N. Pyrsopoulos, R. Reddy, M. Rinella, D. Rockey, M. Rodriguez, M. Ryan, S. Sarkar, S. Satapathy, A. Scanga, M. Shiffman, M. Siddiqui, D. Simonetto, W. Syn, P. Thuluvath, R. Vemulapalli, J. Vierling, Z. Younes, A. Albillos, J. Arenas Ruiz-Tapiador, S. Augustin, J. Calleja, J. Crespo Garcia, L. Garcia Buey, J.C. Garcia-Pagan, C. Villanueva, C. Bureau, N. Carbonell, V. Leroy, P.-E. Rautou, H. Heinzow, I. Schiefke, A. Zipprich, A. Berzigotti, B. Muellhaupt
Publikováno v:
Garcia-Tsao, Guadalupe; Bosch, Jaime; Kayali, Zeid; Harrison, Stephen A; Abdelmalek, Manal F; Lawitz, Eric; Satapathy, Sanjaya K; Ghabril, Marwan; Shiffman, Mitchell L; Younes, Ziad H; Thuluvath, Paul J; Berzigotti, Annalisa; Albillos, Agustin; Robinson, James M; Hagerty, David T; Chan, Jean L; Sanyal, Arun J (2020). Randomized Placebo-Controlled Trial of Emricasan in Non-alcoholic Steatohepatitis (NASH) Cirrhosis with Severe Portal Hypertension. Journal of hepatology, 72(5), pp. 885-895. Elsevier 10.1016/j.jhep.2019.12.010
Background & Aims Emricasan, an oral pan-caspase inhibitor, decreased portal pressure in experimental cirrhosis and in an open-label study in patients with cirrhosis and severe portal hypertension, defined as a hepatic venous pressure gradient (HVPG)