Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Wenyu Lin"'
Autor:
Andrew Yang, Raymond T. Chung, Esperance A. Schaefer, Cynthia Brisac, Lee F. Peng, Christina Mark, Daniel L. Motola, Dahlene N. Fusco, Clary B. Clish, Shadi Salloum, Amy Deik, Wenyu Lin, James Meixiong
Publikováno v:
World Journal of Gastroenterology
AIM To characterize the role of apolipoprotein B100 (apoB100) in hepatitis C viral (HCV) infection. METHODS In this study, we utilize a gene editing tool, transcription activator-like effector nucleases (TALENs), to generate human hepatoma cells with
Autor:
Run-Xuan Shao, Andrew W. Tai, Raymond T. Chung, Lee F. Peng, Ethan M. Weinberg, Sun Suk Kim, Carolina B. De Sa Borges, Wenyu Lin, Kyung Ah Kim, Mark A. Brockman
Publikováno v:
Gastroenterology. 134:803-811
Background & Aims: Human immunodeficiency virus (HIV) coinfection increases hepatitis C virus (HCV)-related progression of hepatic fibrosis, increases HCV persistence, and decreases response rates to interferon-based anti-HCV therapy. It has remained
Autor:
K. Rajender Reddy, Anna E. Rutherford, Edwyn M Harrison, Adrian Reuben, April R. Gorman, David G. Forcione, Wenyu Lin, Linda S. Hynan, Raymond T. Chung, Jason T. Blackard, Carolina B. De Sa Borges, William M. Le, Obaid S. Shaikh
Publikováno v:
Clinical Gastroenterology and Hepatology. 5:1477-1483
Background & Aims: We sought to determine whether circulating apoptotic markers are altered in acute liver failure (ALF), differ with etiology, or predict clinical outcome in this condition. Methods: Serum levels of soluble Fas (sFas), tumor necrosis
Autor:
Stuart L. Schreiber, Lee F. Peng, Sun Suk Kim, Raymond T. Chung, Wenyu Lin, Naoya Sakamoto, Won-Hyeok Choe
Publikováno v:
Gastroenterology. 132:311-320
Background & Aims: Only half of patients with chronic hepatitis C virus (HCV) infection experience sustained virologic response to pegylated-interferon and ribavirin, which cause numerous side effects. Thus, the identification of more effective and b
Autor:
Yoichi Hiasa, Raymond T. Chung, Wenyu Lin, Emmett V. Schmidt, Won Hyeok Choe, Yoshitaka Kamegaya, Jason T. Blackard
Publikováno v:
Gastroenterology. 128:1034-1041
Background & Aims: The molecular mechanisms by which hepatitis C virus (HCV) antagonizes the antiviral actions of interferon (IFN) have not been fully characterized. Specifically, how HCV proteins impact on IFN signaling components has yet to be eluc
Autor:
David Healey, Wenyu Lin, Raymond T. Chung, Betania Negre, David A. Ludwig, Marielle Christofi, Aymin Delgado–Borrego, Yoshitaka Kamegaya, Sergio H. Jordan, Anna S.F. Lok
Publikováno v:
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 8(5)
Hepatitis C virus (HCV) infection is associated with an increased prevalence of diabetes and insulin resistance (IR); whether this is a causal relationship has not been established.We performed a longitudinal study within the lead-in phase of the Hep
Autor:
Raymond T. Chung, Jae Young Jang, Leiliang Zhang, Woo Jin Chung, Lee F. Peng, Wei-Lun Tsai, Lydia L. Barlow, Guoyang Wu, Wenyu Lin, Run-Xuan Shao, Hong Zhao
Publikováno v:
Gastroenterology. 138:2509-2518.e1
Background & Aims The generation of oxidative stress and transforming growth factor β1 (TGF-β1) production play important roles in liver fibrogenesis. We have previously shown that hepatitis C virus (HCV) increases hepatocyte TGF-β1 expression. Ho