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Publikováno v:
Internal Medicine. 61:87-90
A 56-year-old woman with rheumatoid arthritis who had been taking methotrexate (MTX) for six years visited our hospital with dyspnea and dizziness. Abdominal ultrasonography revealed mild splenomegaly. Laboratory examinations showed a marked elevatio
Autor:
Jennifer Foulke-Abel, Kelli F. Johnson, Mark Donowitz, Ruxian Lin, Nicholas C. Zachos, Sun Lee, Varsha Singh, Jianyi Yin, Huimin Yu, Yan Rong, Julie In
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 1, Pp 219-232 (2022)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims One of the features of ulcerative colitis (UC) is a defect in the protective mucus layer. This has been attributed to a reduced number of goblet cells (GCs). However, it is not known whether abnormal GC mucus secretion also contribu
Publikováno v:
Gastroenterology Review. 17:146-151
Introduction: Some observational studies have demonstrated the benefit of famotidine in COVID-19-infected individuals. The preference of using an H-2 receptor antagonist (H(2)RA) over proton pump inhibitors (PPI) during the COVID-19 pandemic has been
Autor:
Mitsuru Ito, Shuji Fukata, Akira Miyauchi, Eijun Nishihara, Toshihiko Kasahara, Takashi Akamiuzu, Mitsushige Nishikawa
Publikováno v:
Endocrine Journal. 69:307-311
Nephrotic syndrome (NS) is characterized by massive urinary protein leakage and associated hypoproteinemia due to increased protein permeability caused by impaired renal glomerular connections. Although there have been several sporadic reports regard
Autor:
Harsh Vardhan Tevethia, Mukesh Ranjan, Siew C. Ng, Rakesh Kochhar, Kirandeep Kaur, Govind K. Makharia, Ajit Sood, Vandana Midha, Stephen B. Hanauer, C. Ganesh Pai, Charles N. Bernstein, Abhinav Anand, Suhang Verma, Joyce Wing Yan Mak, Rupa Banerjee, Saurabh Kedia, Kiran Peddi, Amit Kumar Dutta, Vineet Ahuja, Varun Mehta, Ramit Mahajan, Saroj K. Sinha, Perttu Arkkila, Usha Dutta, Arshdeep Singh, Devendra Desai
Publikováno v:
Intestinal Research, Vol 20, Iss 1, Pp 11-30 (2022)
Inflammatory bowel disease (IBD), once considered a disease of the Western hemisphere, has emerged as a global disease. As the disease prevalence is on a steady rise, management of IBD has come under the spotlight. 5-Aminosalicylates, corticosteroids
Autor:
Fritz Offner, Karima Amaador, Kazem Nasserinejad, Dries Deeren, Efstathios Kastritis, Steven T. Pals, Willem Kraan, Jeanette K. Doorduijn, Roberto D Liu, Monique C. Minnema, Marcel Kap, Marie José Kersten, Lara H Böhmer, Lidwine W. Tick, Meletios A. Dimopoulos, Josephine M.I. Vos, Martine E D Chamuleau, Maria Gavriatopoulou
Publikováno v:
JOURNAL OF CLINICAL ONCOLOGY
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 40(1), 40-51. American Society of Clinical Oncology
Kersten, M J, Amaador, K, Minnema, M C, Vos, J M I, Nasserinejad, K, Kap, M, Kastritis, E, Gavriatopoulou, M, Kraan, W, Chamuleau, M E D, Deeren, D, Tick, L W, Doorduijn, J K, Offner, F, Böhmer, L H, Liu, R D, Pals, S T & Dimopoulos, M A 2022, ' Combining Ixazomib With Subcutaneous Rituximab and Dexamethasone in Relapsed or Refractory Waldenström's Macroglobulinemia : Final Analysis of the Phase I/II HOVON124/ECWM-R2 Study ', Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol. 40, no. 1, pp. 40-51 . https://doi.org/10.1200/JCO.21.00105
Journal of clinical oncology, 40(1), 40-51. American Society of Clinical Oncology
Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 40(1), 40-51. American Society of Clinical Oncology
Kersten, M J, Amaador, K, Minnema, M C, Vos, J M I, Nasserinejad, K, Kap, M, Kastritis, E, Gavriatopoulou, M, Kraan, W, Chamuleau, M E D, Deeren, D, Tick, L W, Doorduijn, J K, Offner, F, Böhmer, L H, Liu, R D, Pals, S T & Dimopoulos, M A 2022, ' Combining Ixazomib With Subcutaneous Rituximab and Dexamethasone in Relapsed or Refractory Waldenström's Macroglobulinemia : Final Analysis of the Phase I/II HOVON124/ECWM-R2 Study ', Journal of clinical oncology : official journal of the American Society of Clinical Oncology, vol. 40, no. 1, pp. 40-51 . https://doi.org/10.1200/JCO.21.00105
Journal of clinical oncology, 40(1), 40-51. American Society of Clinical Oncology
PURPOSE Proteasome inhibitors are effective in Waldenström's macroglobulinemia (WM) but require parenteral administration and are associated with polyneuropathy. We investigated efficacy and toxicity of the less neurotoxic oral proteasome inhibitor
Autor:
Leon P. Loevenich, Thomas Engleitner, Marlies Michl, Sebastian Vosberg, Matjaz Rokavec, Andreas Jung, Heiko Hermeking, Philipp A. Greif, Jens Neumann, Jörg Kumbrink, Roland Rad, Thomas Kirchner, Peter Jung, Rupert Öllinger, Sophie L. Boos
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 2, Pp 517-540 (2022)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Patient-derived tumor organoids recapitulate the characteristics of colorectal cancer (CRC) and provide an ideal platform for preclinical evaluation of personalized treatment options. We aimed to model the acquisition of chemotolera
Autor:
Michail Doukas, Merel van Pieterson, Sarah T A Teklenburg-Roord, Herbert M. van Wering, Lissy de Ridder, Dimitris Rizopoulos, Martinus A. Cozijnsen, Maria M E Jongsma, Obbe F. Norbruis, Michiel P. van Wijk, Marco W.J. Schreurs, Thalia Hummel, Johanna C. Escher, Janneke M. Stapelbroek, Michael Groeneweg, Kaija-Leena Kolho, Cathelijne van der Feen, Iva Hojsak, Tim G. J. de Meij, Janneke N. Samsom, M Aardoom, Victorien M. Wolters, Patrick F. van Rheenen
Publikováno v:
Jongsma, M M E, Aardoom, M A, Cozijnsen, M A, van Pieterson, M, de Meij, T, Groeneweg, M, Norbruis, O F, Wolters, V M, van Wering, H M, Hojsak, I, Kolho, K-L, Hummel, T, Stapelbroek, J, van der Feen, C, van Rheenen, P F, van Wijk, M P, Teklenburg-Roord, S T A, Schreurs, M W J, Rizopoulos, D, Doukas, M, Escher, J C, Samsom, J N & de Ridder, L 2022, ' First-line treatment with infliximab versus conventional treatment in children with newly diagnosed moderate-to-severe Crohn's disease: An open-label multicentre randomised controlled trial ', Gut, vol. 71, no. 1, pp. 34-42 . https://doi.org/10.1136/gutjnl-2020-322339
Gut, 71(1), 34-42. BMJ Publishing Group
Gut, 71, 34-42. BMJ PUBLISHING GROUP
Gut, 71(1), 34-42. BMJ Publishing Group
Gut, 71, 34-42. BMJ PUBLISHING GROUP
ObjectiveIn newly diagnosed paediatric patients with moderate-to-severe Crohn’s disease (CD), infliximab (IFX) is initiated once exclusive enteral nutrition (EEN), corticosteroid and immunomodulator therapies have failed. We aimed to investigate wh
Autor:
Amel Zerroukhi, Martha Duraes, Julien Baleine, Jean-François Schved, Isabelle Cau-Diaz, Tarik Kanouni, Elodie Boissier, Olivier Dautremay, Lionel Moulis, Alexandre Theron, Eric Jeziorski, Christine Biron-Andreani, Michel Rodière
Publikováno v:
Blood Advances
Key Points IPF has a typical clinical presentation with involvement of the lower limbs corresponding to vascular territories.The antithrombin level and platelet count at diagnosis seemed to be associated with severe complications in IPF.
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Autor:
Rafael Sartori Balbinot, Silvana Sartori Balbinot, Louise Zanotto Eberhardt, Raul Angelo Balbinot, Gilberto Luis Rost, Juline Isabel Leichtweis Balensiefer, Ana Laura Facco Muscope, Bruna Schena, Morgana Luisa Longen, Alana Zulian Terres, Jonathan Soldera, Bruna Teston Cini
Publikováno v:
Gastroenterología y Hepatología. 45:25-39
Hepatorenal syndrome (HRS) is the deadliest complication of cirrhosis. The purpose of this study is to analyze if the use of a protocol for HRS is associated with higher survival in these patients.An evidence-based protocol for the diagnosis and trea