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Autor:
Yoshiaki Murakami, Shingo Seo, Hiroyuki Otsuka, Yasushi Hashimoto, Naru Kondo, Shinya Takahashi, Takeshi Sudo, Kenjiro Okada, Tatsuaki Sumiyoshi, Kenichiro Uemura
Publikováno v:
European Journal of Cancer. 159:215-223
Background The prognosis of patients with borderline resectable pancreatic cancer with arterial contact (BRPC-A) is extremely poor, and effective preoperative treatment is indispensable. We evaluated the clinical efficacy and safety of neoadjuvant ch
Autor:
Yang Zhu, Shu Tian, Hua Zhong, Wenhao Zhang, Lifeng Wang, Rong Tao, Zhi-Chao Li, Hao Ding, Lina Jin, Chuanying Zhu, Yu-Jie Ma, Chuan-xu Liu, Siguo Hao, Lan Xu
Publikováno v:
British Journal of Haematology. 196:939-946
Early-stage natural killer/T-cell lymphoma (NK/TCL) patients usually receive a combination of chemotherapy and radiotherapy, but the optimal treatment approach has not yet been established. This study aimed to investigate the efficacy and safety prof
Autor:
Kohei Higuchi, Mariko Shimizu, Maho Koyama-Sato, Yosuke Okada, Masami Inoue, Shota Inoue, Kimitoshi Goto, Akihisa Sawada, Masahiro Yasui
Publikováno v:
International Journal of Hematology. 115:269-277
Graft failure is a major pitfall of unrelated umbilical cord blood transplantation (CBT) in children with rare hematological disorders other than acute leukemia, such as acquired and inherited bone marrow failure, myelodysplastic syndrome, juvenile m
Autor:
Shogo Teraoka, Atsushi Takenaka, Katsuya Hikita, Masashi Honda, Hideto Iwamoto, Shuichi Morizane, Bunya Kawamoto, Noriya Yamaguchi, Tetsuya Yumioka, Ryutaro Shimizu
Publikováno v:
Anticancer Research. 41:5767-5773
BACKGROUND This study aimed to investigate the response to platinum-based chemotherapy rechallenge in patients with pembrolizumab-refractory urothelial carcinoma. PATIENTS AND METHODS We retrospectively reviewed 14 patients with pembrolizumab-refract
Publikováno v:
Pharmacology. 107:69-80
Introduction: This study was conducted to develop and validate a nomogram for predicting the risk of neutropenia or febrile neutropenia (FN) in tumor patients in the first cycle of etoposide-based chemotherapy. Methods: This retrospective cohort stud
Autor:
Xiaoyong Huang, Zhiqiang Wu, Wenbo Guo, Zhiyong Liu, Tengfei Li, Xu Bo, Weiguang Yu, Song Chen, Yanqing Wu, Pengfei Wang
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-13 (2021)
BMC Cancer
BMC Cancer
Background Not all patients with unresectable hepatocellular carcinoma (uHCC) benefit from treatment with immune checkpoint inhibitors and molecular-targeted agents. The aim of this retrospective study was to assess the efficacy and safety of pembrol
Autor:
Joy Peter, Larry Michael, Rakesh Tripathi, Gurjit S. Sidhu, Ryan Tamashiro, Lois Larsen, Gary P. Wang, Jens Kort, David R. Nelson, Gretja Schnell, Joan A. Whitlock, Michael W. Fried, Layla Schuster, Ken Bergquist, Chandni B. Patel, Ashley Magee
Publikováno v:
Journal of Hepatology. 75:820-828
Background & Aims Retreatment with glecaprevir/pibrentasvir (G/P) resulted in a rate of sustained virologic response 12 weeks after treatment completion (SVR12) of >90% in HCV genotype 1 (GT1) patients who previously failed a regimen of sofosbuvir pl
Autor:
Koichi Inoue, Toshihiko Doi, Noboru Yamamoto, Yasutoshi Kuboki, Takafumi Koyama, Hiroya Asou, Naoto Tsujimoto, Yongzhe Piao, Yoichi Naito, Shunsuke Kondo
Publikováno v:
Cancer Medicine, Vol 10, Iss 19, Pp 6579-6589 (2021)
Cancer Medicine
Cancer Medicine
This phase 1, multi‐center, nonrandomized, open‐label, dose‐escalation study consisted of Part A wherein merestinib 80 or 120 mg (40‐mg tablets) was administered orally QD during a 28‐day cycle to patients diagnosed with solid tumors and Pa
Autor:
Naoyuki Uchida, Makoto Murata, Ritsuro Suzuki, Yasushi Onishi, Hirohito Yamazaki, Satoshi Yoshioka, Takehiko Mori, Akinori Nishikawa, Tetsuya Eto, Tatsuo Ichinohe, Takafumi Kimura, Yukinori Nakamura, Nobuhiro Hiramoto, Yoshiko Atsuta, Tadakazu Kondo
Publikováno v:
Annals of Hematology. 101:165-175
Thus far, there have been no large cohort studies on total body irradiation (TBI)-containing conditioning regimens without antithymocyte globulin (ATG) in adults with aplastic anemia (AA) undergoing umbilical cord blood (UCB) transplantation (UCBT).
Autor:
Zahra Mahmoudjafari, Al-Ola Abdallah, Joseph P. McGuirk, Nausheen Ahmed, Wei Cui, Meera Mohan, Ghulam Rehman Mohyuddin, Ryan Hawkins, Leyla Shune, Siddhartha Ganguly, Shebli Atrash, Dante Pennipede
Publikováno v:
European Journal of Haematology. 107:602-608
Background Multiple myeloma (MM) is an incurable hematologic malignancy, and outcomes remain poor for patients with triple-class relapsed/refractory MM (RRMM). Descriptive analyses were performed on available data for patient characteristics, disease