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Akademický článek
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Autor:
Girolamo Cirrincione, Alessia Salvador, Francesco Dall'Acqua, Paola Barraja, Daniela Vedaldi, Alessandra Montalbano, Giampietro Viola, Patrizia Diana, Giuseppe Basso, Anna Carbone
Publikováno v:
Bioorganic & Medicinal Chemistry. 19:2326-2341
Pyrrolo[3,4- h ]quinolin-2-ones were synthesized as nitrogen isosters of the angular furocoumarin angelicin, with the aim of obtaining new photochemotherapeutic agents with increased antiproliferative activity and lower undesired toxic effects. A ver
Autor:
Barbara Cosimelli, Francesco Dall'Acqua, Daniela Vedaldi, Marco Boccalini, Giampietro Viola, Stefano Chimichi
Publikováno v:
Tetrahedron. 58:4859-4863
An efficient synthesis (yields >70%) of linear 7H-furo[3,2-g]chromen-7-one derivatives (psoralens or furocoumarins) has been carried out starting from ring-substituted 2-(coumarin-7-yl)oxyaldehydes; moreover, the phototoxicity of these compounds has
Autor:
Girolamo Cirrincione, Ignazio Castagliuolo, Alessia Salvador, Libero Caracausi, Giorgio Palù, Patrizia Diana, Paola Barraja, Daniela Vedaldi, Paola Brun, Francesco Dall'Acqua, Anna Carbone, Alessandra Montalbano
In the search for new photochemotherapeutic agents, a series of derivatives of the ring system pyrrolo[3,2-h]quinoline--bioisosters of the angular furocoumarin angelicin--were synthesized through a four-step synthetic approach, in reasonable overall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88da20c1b189b679b3f317089fdf0a14
http://hdl.handle.net/10447/51294
http://hdl.handle.net/10447/51294
THIOPYRANO[2,3-E]INDOL-2-ONES: ANGELICIN HETEROANALOGUES WITH POTENT PHOTOANTIPROLIFERATIVE ACTIVITY
Autor:
Patrizia Diana, Giampietro Viola, Alessia Salvador, Alessandra Montalbano, Girolamo Cirrincione, Paola Barraja, Daniela Vedaldi, Anna Carbone, Francesco Dall'Acqua
A new class of compounds, the thiopyrano[2,3-e]indol-2-ones, bioisosters of the angular furocoumarin angelicin, was synthesized with the aim of obtaining new photochemotherapeutic agents. In particular 7,8-dimethyl-thiopyranoindolone 6c s showed a re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::573c605814c6c64b997aa389120a5017
https://hdl.handle.net/11567/1024312
https://hdl.handle.net/11567/1024312
Autor:
Giampietro Viola, Patrizia Diana, Girolamo Cirrincione, Gaetano Dattolo, Francesco Dall'Acqua, Paola Barraja, Daniela Vedaldi, Alessandra Montalbano
A new class of compounds, the pyrrolo[2,3-h]quinolin-2-ones, nitrogen isosters of the angular furocoumarin Angelicin, was synthesized with the aim of obtaining new photochemotherapeutic agents with increased antiproliferative activity and lower undes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31f388ebf421ac7dda26fd0bd0aea9fa
http://hdl.handle.net/11577/2447640
http://hdl.handle.net/11577/2447640