Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ken-ichi Noma"'
Autor:
Shuai Wu, Katherine M. Aird, Joseph A. Zundell, David W. Speicher, Takeshi Fukumoto, David C. Schultz, Ken-ichi Noma, Zachary T. Schug, Osamu Iwasaki, Lena Lau, Rugang Zhang, Timothy Nacarelli, Nail Fatkhutdinov, Hsin Yao Tang, Joseph A. Baur, Andrew V. Kossenkov, Gregory David
Publikováno v:
Nature Cell Biology. 21:397-407
Cellular senescence is a stable growth arrest that is implicated in tissue ageing and cancer. Senescent cells are characterized by an upregulation of proinflammatory cytokines, which is termed the senescence-associated secretory phenotype (SASP). NAD
Autor:
F. Brad Johnson, Osamu Iwasaki, Andrew V. Kossenkov, Linh Le, Gretchen M. Alicea, Hideki Tanizawa, Ting-Lin B. Yang, Nail Fatkhutdinov, Benjamin G. Bitler, Ken-ichi Noma, Katherine M. Aird, Rugang Zhang
Publikováno v:
The Journal of Cell Biology
In senescence, specific genes encoding secreted factors are excluded from senescence-associated heterochromatin foci, but the mechanisms underlying this senescence-associated secretory phenotype (SASP) are unclear. Aird et al. show that the chromatin
Autor:
Timothy, Nacarelli, Lena, Lau, Takeshi, Fukumoto, Joseph, Zundell, Nail, Fatkhutdinov, Shuai, Wu, Katherine M, Aird, Osamu, Iwasaki, Andrew V, Kossenkov, David, Schultz, Ken-Ichi, Noma, Joseph A, Baur, Zachary, Schug, Hsin-Yao, Tang, David W, Speicher, Gregory, David, Rugang, Zhang
Publikováno v:
Nature cell biology
Cellular senescence is a stable growth arrest that is implicated in tissue ageing and cancer. Senescent cells are characterized by an upregulation of proinflammatory cytokines, which is termed the senescence-associated secretory phenotype (SASP). NAD
Publikováno v:
Science. 304:1971-1976
At the silent mating-type interval of fission yeast, the RNA interference (RNAi) machinery cooperates with cenH , a DNA element homologous to centromeric repeats, to initiate heterochromatin formation. However, in RNAi mutants, heterochromatin assemb
Publikováno v:
Genes & Genetic Systems. 72:131-140
RIRE1 is a retrotransposon present in wild rice Oryza australiensis in an extraordinary number of copies, and only a portion of the LTR sequence has been determined previously. Here, we isolated and sequenced DNA segments of various portions of RIRE1
Autor:
Eishi Noguchi, Ken-ichi Noma, Hideki Tanizawa, Mukund M. Das, Ya Ting Chang, Mariana C. Gadaleta, Toru Nakamura
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 12, Iss 3, p e1005943 (2016)
PLoS Genetics, Vol 12, Iss 3, p e1005943 (2016)
Genomic instability associated with DNA replication stress is linked to cancer and genetic pathologies in humans. If not properly regulated, replication stress, such as fork stalling and collapse, can be induced at natural replication impediments pre
RNA interference machinery regulates chromosome dynamics during mitosis and meiosis in fission yeast
The regulation of higher-order chromosome structure is central to cell division and sexual reproduction. Heterochromatin assembly at the centromeres facilitates both kinetochore formation and sister chromatid cohesion, and the formation of specialize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::718e43a1a1bffb31e246ef201a5734d0
https://europepmc.org/articles/PMC140924/
https://europepmc.org/articles/PMC140924/
Autor:
Hugh P. Cam, Ken-ichi Noma, Martin Zofall, Tomoyasu Sugiyama, Ryuji Kobayashi, Shiv I. S. Grewal, Rie Sugiyama
Publikováno v:
Cell. (3):491-504
Summary Transcriptional gene silencing (TGS) is the mechanism generally thought by which heterochromatin effects silencing. However, recent discovery in fission yeast of a cis -acting posttranscriptional gene-silencing ( cis -PTGS) pathway operated b