Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Karel Souček"'
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2543
Multicolor flow cytometry allows for analysis of tens of cellular parameters in millions of cells at a single-cell resolution within minutes. The lack of technologies that would facilitate feasible and relatively cheap profiling of such a number of c
Autor:
Jan Bouchal, Wytske M. van Weerden, Vladimír Študent, Zoran Culig, Martin Morong, Stanislav Drápela, Daniela Kurfürstová, Barbora Kvokackova, Radek Fedr, Martin Puhr, Karel Souček
BackgroundDocetaxel resistance represents a leading obstacle in the therapy of prostate cancer (PCa), resulting in lethal disease. Intratumoral heterogeneity, which is frequently driven by epithelial-mesenchymal plasticity significantly contributes t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c06e0a02611c88c6759b3e22b9c27403
https://doi.org/10.1101/2021.01.28.428577
https://doi.org/10.1101/2021.01.28.428577
Publikováno v:
Cytometry Part A. 93:239-248
Complex analysis of cellular responses after experimental treatment is important for screening, mechanistic understanding of treatment effects, and the identification of sensitive and resistant cell phenotypes. Modern multicolor flow cytometry has de
Autor:
Peter Kollar, Tatiana Syrovets, Tereza Kauerová, Radek Fedr, Tomáš Goněc, Ann-Kathrin Gaiser, Karel Souček, Josef Jampilek, Susanne Hafner
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 3416, p 3416 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 10
International Journal of Molecular Sciences
Volume 21
Issue 10
Ring-substituted 1-hydroxynaphthalene-2-carboxanilides were previously investigated for their antimycobacterial properties. In our study, we have shown their antiproliferative and cell death-inducing effects in cancer cell lines. Cell proliferation a
Autor:
Rastislav Jendželovský, Radek Fedr, Jaromír Mikeš, Karel Souček, Peter Fedoročko, Alois Kozubík, Lucia Mikešová, Barbora Kuchárová, Ján Remšík, Ľubomír Čulka, Jana Vargová
Publikováno v:
Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 99
Objective Cancer stem-like cells (CSLCs) are considered a root of tumorigenicity and resistance. However, their identification remains challenging. The use of the side population (SP) assay as a credible marker of CSLCs remains controversial. The SP
Autor:
Radek Fedr, Jiří Navrátil, Pavel Fabian, Marek Svoboda, Eva Slabáková, Ján Remšík, Lucia Binó, Karel Souček
Publikováno v:
British Journal of Cancer
Background: The intratumoural heterogeneity, often driven by epithelial-to-mesenchymal transition (EMT), significantly contributes to chemoresistance and disease progression in adenocarcinomas. Methods: We introduced a high-throughput screening platf
Publikováno v:
Cytometry. Part A : the journal of the International Society for Analytical Cytology. 93(2)
Complex analysis of cellular responses after experimental treatment is important for screening, mechanistic understanding of treatment effects, and the identification of sensitive and resistant cell phenotypes. Modern multicolor flow cytometry has de
Autor:
János Szöllősi, Viktor Horváth, Jiřina Hofmanová, Alois Kozubík, Ladislav Anděra, Alena Hyršlová Vaculová, György Vereb, Petr Sova, Olga Vondálová Blanářová, Karel Souček, Árpád Szöőr, Belma Skender, Iva Jelínková
Publikováno v:
Carcinogenesis. 32:42-51
TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) can selectively trigger apoptosis in various cancer cell types. However, many cancer cells are resistant to death receptor-mediated apoptosis. Combination therapy with platinum complexes
Autor:
Tomáš Bárta, Karel Šmejkal, Veronika Závalová, Jan Hošek, Pavlína Trnová, Peter Kollar, Aleš Hampl, Karel Souček, Stanislava Keltosova, Radek Fedr
Publikováno v:
Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-Based Complementary and Alternative Medicine, Vol 2015 (2015)
Evidence-Based Complementary and Alternative Medicine, Vol 2015 (2015)
Aims. In this work we studied cytodifferentiation effects of newly characterized prenyl flavonoid 4′-O-methylkuwanon E (4ME) isolated from white mulberry (Morus albaL.).Main Methods. Cell growth and viability were measured by dye exclusion assay; c
Autor:
Karel Šmejkal, Jan Hošek, Veronika Závalová, Rabih S. Talhouk, Shushan B. Artinian, Pavel Suchý, Aleš Hampl, Karel Souček, Tomáš Bárta, Peter Kollar
Publikováno v:
Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-Based Complementary and Alternative Medicine, Vol 2013 (2013)
Evidence-Based Complementary and Alternative Medicine, Vol 2013 (2013)
Morus albaL. (MA) is a natural source of many compounds with different biological effects. It has been described to possess anti-inflammatory, antioxidant, and hepatoprotective activities. The aim of this study was to evaluate cytotoxicity of three f