Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Anil Pahuja"'
Autor:
Reinhold Pollner, Ghanashyam Sarikonda, Kevin Nguyen, Anil Pahuja, Creton Kalfoglou, Kerri Burns, Naveen Dakappagari, Irene L. Ch’en, Shabnam Tangri
Publikováno v:
Cytometry Part B: Clinical Cytometry. 100:72-78
Exceptional clinical responses produced by the first chimeric antigen receptor T [CAR-T] cell therapies, and their entry into commercial markets prompted a logarithmic increase in the number of next generation CAR-T clinical trials. As a result, ther
Autor:
Paul C Trampont, Ghanashyam Sarikonda, Virginia Litwin, Laïla-Aïcha Hanafi, Vilma Decman, Anil Pahuja, Yongliang S Sun, Mélissa Mathieu, Michael Nathan Hedrick, Susan Reynolds, Steven Eck, Qiong Xue, Naveen Dakappagari, Jennifer J. Stewart, Shabnam Tangri, Mahwish Natalia, Piotr L Pierog
Publikováno v:
Cytometry. Part B, Clinical cytometryREFERENCES. 100(1)
Chimeric Antigen Receptor (CAR) T cells are recognized as efficacious therapies with demonstrated ability to produce durable responses in blood cancer patients. Regulatory approvals and acceptance of these unique therapies by patients and reimburseme
Autor:
Ahmad A Tarhini, Arjun Khunger, Jane Gao, Ghanashyam Sarikonda, Zeni Alfonso, Naveen Dakappagari, Christian Laing, Jennifer Tsau, Christine Vaupel, Anil Pahuja
Publikováno v:
Translational Oncology, Vol 14, Iss 3, Pp 101014-(2021)
Translational Oncology
Translational Oncology
Highlights • Neoadjuvant ipilimumab and IFNα were evaluated in regionally advanced melanoma. • Immune cellular profiling investigated tumor immune susceptibility and resistance. • Higher levels of peripheral Th1 cell subsets predicted favorabl
Autor:
Anil Pahuja, Thomas R. Ott, Warren Wade, Molly M. Gross, Sarah Hudson, Francisco M. Lio, David G. Alleva, Pedro B. Simpson, R. Scott Struthers, Monica S. Mistry
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 51:105-114
Introduction: Higher-throughput chemotaxis assays have had limited use in chemokine receptor pharmacology studies mainly because of the unavailability of optimal assay formats in addition to an incompatibility of chemotactic cell backgrounds with oth
Autor:
Naveen Dakappagari, Shabnam Tangri, Shyam Sarikonda, Anil Pahuja, Armin Graber, Benjamin H. Lee
Publikováno v:
Cancer Research. 75:3388-3388
Propelled by the advent of novel oncogenic pathway-targeting drugs and increasing regulatory expectations to fulfil proof of mechanism endpoints in clinical trials, there is a critical need to reliably evaluate target inhibition by investigational dr
Autor:
Devika Ashok, Anil Pahuja, Ghanashyam Sarikonda, Naveen Dakappagari, Jelveh Lameh, Shabnam Tangri
Publikováno v:
Cancer Research. 75:1302-1302
The renaissance of cancer immunotherapies and the positive clinical responses observed with chimeric antigen receptor modified T cells in the hematomalignancy setting has stimulated substantial interest in monitoring immune cell activation and suppre
Autor:
Naveen Dakappagari, Armin Graber, Benjamin H. Lee, Shyam Sarikonda, Shabnam Tangri, Jelveh Lameh, Anil Pahuja, Abdel Saci
Publikováno v:
Cancer Research. 74:LB-96
Propelled by the advent of new technologies and an evolving regulatory landscape, the desire to personalize cancer treatments has never been greater. There is a critical need to reliably evaluate target inhibition and pharmacodynamic activity of inve