Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Wenbing Yao"'
Autor:
Xiaoda Song, Tao Jiang, Hong Tian, Yue Tong, Jianhua Luo, Xiangdong Gao, Wenbing Yao, Liangliang Jiang, Yanliang Kang
Publikováno v:
Journal of Immunology Research
Journal of Immunology Research, Vol 2019 (2019)
Journal of Immunology Research, Vol 2019 (2019)
Single B cell antibody technology is a method for isolating antigen-specific B cells from human peripheral blood and obtaining antibody genes in developing antibody drugs. However, owing to immune tolerance to autoantigen, human autoantigen-specific
Autor:
Dingkang Liu, Chen Ye, Qun Wang, Jun Yin, Shan Hou, Lichen Bao, Xiangdong Gao, Wenbing Yao, Yali Yue
Publikováno v:
Cancer Letters. 452:38-50
The great therapeutic potential of peptides has not yet been achieved, mainly due to their remarkably short in vivo half-life. Although conjugation to macromolecules has been an effective way of improving protein in vivo half-life, the steric hindran
Autor:
Liangliang Jiang, Weisheng Lu, Wei Liu, Chun Pan, Hong Tian, Xiangdong Gao, Jianhua Luo, Wenbing Yao, Xingqun Gong
Publikováno v:
Carbohydrate polymers. 263
Immunological adjuvants are an important part of tumor vaccines and are critical for stimulating anti-tumor immune responses. However, the clinical needs of strong adjuvants have not been met. In this work, we found that the purified acidic polysacch
Publikováno v:
BMC Health Services Research, Vol 20, Iss 1, Pp 1-9 (2020)
BMC Health Services Research
BMC Health Services Research
Background Pharmaceutical care is attached with increasing importance around the world due to its clinical and economical effects. Tertiary hospitals are equipped with the richest healthcare resources and pioneer in the implementation of pharmaceutic
Publikováno v:
Australian journal of primary health. 26(5)
China is attempting to establish a pharmacy services network in primary healthcare (PHC) institutions. This study investigated the current status of pharmacy services in China. Following a conceptual framework derived from the structure–process–o
Autor:
Yanliang Kang, Wanli Zhang, Xingqun Gong, Wenbing Yao, Hongmei Chen, Xiaodao Song, Yi Xu, Hong Tian, Xiangdong Gao, Xuefei Xia, Yunyan Xu
Publikováno v:
Cancer letters. 476
Despite the clinical success of immune checkpoint blockade, only a subset of people exhibits durable responses, suggesting that an alternative immunotherapeutic strategy is required. This paper reported a two-in-one cancer vaccine that targets progra
Autor:
Xiaoda Song, Liangliang Jiang, Xiangdong Gao, Wanli Zhang, Yi Xu, He Yu, Hong Tian, Jianhua Luo, Wenbing Yao
Publikováno v:
Cancer Letters. 430:79-87
Human epidermal growth factor receptor 2 (HER2) is an attractive target for cancer vaccine. However, autoimmune tolerance prevents vaccines based on HER2 protein from inducing long-lasting, highly effective anti-tumor immunity. In this study, we prov
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 119, Iss, Pp-(2019)
B-cell activating factor (BAFF) plays a key role in the normal regulation of B cell development and immune response. Its abnormal expression level is accompanied by the occurrence of various autoimmune diseases. Therefore, BAFF is an effective target
Autor:
Qianwen Li, Dongmei Yu, Wei Guo, Yucong Chen, Shuo Li, Xiangdong Gao, Wenyao Xue, Wen Lei, Yaoyao Ge, Wenbing Yao
Publikováno v:
International Immunopharmacology. 47:141-149
IL-23/STAT3 signaling pathway is a key process in Th17 cell differentiation, and Th17 cells are closely related to the development of autoimmune diseases. We previously designed and prepared rhIL23R-CHR protein to antagonize endogenous IL-23, showing
Publikováno v:
Biomedicine & Pharmacotherapy. 88:991-998
Human ErbB-2 (Her-2) is a critical target for cancer immunotherapy, and its over-expression can promote cancer migration and invasion. Compared with passive antibody therapy, vaccination treatment is more effective in the prevention of cancer recurre