Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Veronica Vella"'
Autor:
Domenica Scordamaglia, Francesca Cirillo, Marianna Talia, Maria Francesca Santolla, Damiano Cosimo Rigiracciolo, Lucia Muglia, Azzurra Zicarelli, Salvatore De Rosis, Francesca Giordano, Anna Maria Miglietta, Ernestina Marianna De Francesco, Veronica Vella, Antonino Belfiore, Rosamaria Lappano, Marcello Maggiolini
Publikováno v:
Journal of translational medicine. 20(1)
Background Metabolic disorders are associated with increased incidence, aggressive phenotype and poor outcome of breast cancer (BC) patients. For instance, hyperinsulinemia is an independent risk factor for BC and the insulin/insulin receptor (IR) ax
Autor:
Veronica Vella, Ernestina Marianna De Francesco, Alfredo Pulvirenti, Michele Pellegrino, Paolo Vigneri, Alessandra Dicitore, Antonino Belfiore, Marika Giuliano, Michele Massimino, Rosamaria Lappano, Andrea Morrione, Alessandro La Ferlita, Germano Gaudenzi, Andrew H. Sims, Marcello Maggiolini, Roberta Malaguarnera, Salvatore Alaimo, Giovanni Vitale, Alfredo Ferro
Publikováno v:
Cells, Vol 10, Iss 3145, p 3145 (2021)
Cells
Volume 10
Issue 11
Vella, V, Giuliano, M, La Ferlita, A, Pellegrino, M, Gaudenzi, G, Alaimo, S, Massimino, M, Pulvirenti, A, Dicitore, A, Vigneri, P, Vitale, G, Malaguarnera, R, Morrione, A, Sims, A H, Ferro, A, Maggiolini, M, Lappano, R, De Francesco, E M & Belfiore, A 2021, ' Novel Mechanisms of Tumor Promotion by the Insulin Receptor Isoform A in Triple-Negative Breast Cancer Cells ', Cells, vol. 10, no. 11, pp. 3145 . https://doi.org/10.3390/cells10113145
Cells
Volume 10
Issue 11
Vella, V, Giuliano, M, La Ferlita, A, Pellegrino, M, Gaudenzi, G, Alaimo, S, Massimino, M, Pulvirenti, A, Dicitore, A, Vigneri, P, Vitale, G, Malaguarnera, R, Morrione, A, Sims, A H, Ferro, A, Maggiolini, M, Lappano, R, De Francesco, E M & Belfiore, A 2021, ' Novel Mechanisms of Tumor Promotion by the Insulin Receptor Isoform A in Triple-Negative Breast Cancer Cells ', Cells, vol. 10, no. 11, pp. 3145 . https://doi.org/10.3390/cells10113145
The insulin receptor isoform A (IR-A) plays an increasingly recognized role in fetal growth and tumor biology in response to circulating insulin and/or locally produced IGF2. This role seems not to be shared by the IR isoform B (IR-B). We aimed to di
Autor:
Andrea Morrione, Maria Grazia Muoio, Veronica Vella, Ernestina Marianna De Francesco, Maria Luisa Nicolosi, Maria Giovanna Majorana, Marcello Maggiolini, Antonino Belfiore, Rosamaria Lappano, Marika Giuliano, Małgorzata Anna Marć
Publikováno v:
Biomolecules, Vol 11, Iss 926, p 926 (2021)
Biomolecules
Volume 11
Issue 7
Biomolecules
Volume 11
Issue 7
The insulin receptor isoform A (IR-A), a dual receptor for insulin and IGF2, plays a role in breast cancer (BC) progression and metabolic reprogramming. Notably, discoidin domain receptor 1 (DDR1), a collagen receptor often dysregulated in cancer, is
Autor:
Lucia Frittitta, Andrea Tumminia, Agostino Milluzzo, Veronica Vella, Laura Sciacca, Riccardo Vigneri, Fiorenza Gianì, Antonino Belfiore, Livia Manzella
Publikováno v:
Journal of Chemotherapy. 31:150-159
The short-term adverse effects of anticancer drugs (AD) in patients with type 2 diabetes (T2D) are poorly studied and their management still represents an important challenge for clinicians. We carried out a retrospective single-center study in 168 p
Autor:
Francesco Frasca, Antonino Belfiore, Marco Russo, Rosario Le Moli, Pasqualino Malandrino, Veronica Vella
Publikováno v:
Hormones (Athens, Greece). 20(1)
Immune checkpoint blockade therapy may lead to thyroid dysfunction in 3–7% of treated patients. Alemtuzumab is a CD52 inhibitor leading to thyroid dysfunction in approximately 40% of patients. A female patient was affected by multiple sclerosis (MS
Autor:
Domenico Ciavardelli, Maria Bellomo, Veronica Vella, Manuela Pennisi, Giuseppe Lanza, Gera Destro, Rita Bella, Stella Silvia Centonze
Publikováno v:
Complementary Therapies in Medicine. 38:74-78
Objectives Among the complementary and alternative medicine, Shiatsu might represent a feasible option for depression in Alzheimer’s disease (AD). We evaluated Shiatsu on mood, cognition, and functional independence in patients undergoing physical
Autor:
Andrea Morrione, Veronica Vella, Rosamaria Lappano, Maria Luisa Nicolosi, Marco Ragusa, Roberta Malaguarnera, Antonino Belfiore
Publikováno v:
Cell Adhesion & Migration. :1-10
In the last decades increasing importance has been attributed to the Insulin/Insulin-like Growth Factor signaling (IIGFs) in cancer development, progression and resistance to therapy. In fact, IIGFs is often deregulated in cancer. In particular, the
Autor:
Andrea Morrione, Chiara Palladino, Veronica Vella, Michele Massimino, Cristina Barbara Spoleti, Antonino Belfiore, Paolo Vigneri, Marco Ragusa, Maria Luisa Nicolosi, Michele Purrello, Roberta Malaguarnera
Publikováno v:
Oncotarget
The fetal isoform A of the insulin receptor (IR-A) is frequently overexpressed in a variety of malignancies including breast cancer. IR overexpression has a recognized role in cancer progression and resistance to anticancer therapies. In particular,
Autor:
Marika Giuliano, Veronica Vella, Andrea Morrione, Roberta Malaguarnera, Maria Luisa Nicolosi, Antonino Belfiore
Publikováno v:
Cells
Volume 8
Issue 9
Cells, Vol 8, Iss 9, p 1017 (2019)
Volume 8
Issue 9
Cells, Vol 8, Iss 9, p 1017 (2019)
Previously published work has demonstrated that overexpression of the insulin receptor isoform A (IR-A) might play a role in cancer progression and metastasis. The IR has a predominant metabolic role in physiology, but the potential role of IR-A in c