Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Stovell, Matthew"'
Autor:
Khellaf, Abdelhakim, Garcia, Nuria Marco, Tajsic, Tamara, Alam, Aftab, Stovell, Matthew, Killen, Monica J, Howe, Duncan J, Guilfoyle, Mathew R, Jalloh, Ibrahim, Timofeev, Ivan, Murphy, Mike, Carpenter, Adrian, Menon, David K, Ercole, Ari, Hutchinson, Peter, Carpenter, Keri, Thelin, Eric, Helmy, Adel
Following traumatic brain injury (TBI), raised cerebral lactate/pyruvate ratio (LPR) reflects impaired energy metabolism. Raised LPR correlates with poor outcome and mortality following TBI. We prospectively recruited patients with TBI requiring neur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6dcfce8dfd541ebfe048c3444edad7b
https://www.repository.cam.ac.uk/handle/1810/325327
https://www.repository.cam.ac.uk/handle/1810/325327
Autor:
Stovell, Matthew G, Mada, Marius O, Carpenter, T Adrian, Yan, Jiun-Lin, Guilfoyle, Mathew R, Jalloh, Ibrahim, Welsh, Karen E, Helmy, Adel, Howe, Duncan J, Grice, Peter, Mason, Andrew, Giorgi-Coll, Susan, Gallagher, Clare N, Murphy, Michael P, Menon, David K, Hutchinson, Peter J, Carpenter, Keri LH
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism
Metabolic dysfunction is a key pathophysiological process in the acute phase of traumatic brain injury (TBI). Although changes in brain glucose metabolism and extracellular lactate/pyruvate ratio are well known, it was hitherto unknown whether these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::70be7e61a19d1710e9aa9023527e6fb5
https://www.repository.cam.ac.uk/handle/1810/284760
https://www.repository.cam.ac.uk/handle/1810/284760
Autor:
Guilfoyle, Mathew R, Helmy, Adel, Donnelly, Joseph, Stovell, Matthew G, Timofeev, Ivan, Pickard, John D, Czosnyka, Marek, Smielewski, Peter, Menon, David, Carpenter, Keri, Hutchinson, Peter
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0260291 (2021)
PLoS ONE
PLoS ONE
Funder: Evelyn Trust; funder-id: http://dx.doi.org/10.13039/501100004282
Funder: Raymond and Beverly Sackler Foundation; funder-id: http://dx.doi.org/10.13039/100013112
Traumatic brain injury (TBI) is a major cause of death and disability,
Funder: Raymond and Beverly Sackler Foundation; funder-id: http://dx.doi.org/10.13039/100013112
Traumatic brain injury (TBI) is a major cause of death and disability,
Autor:
Stovell, Matthew G., Mada, Marius O., Helmy, Adel, Carpenter, T. Adrian, Thelin, Eric P., Yan, Jiun-Lin, Guilfoyle, Mathew R., Jalloh, Ibrahim, Howe, Duncan J., Grice, Peter, Mason, Andrew, Giorgi-Coll, Susan, Gallagher, Clare N., Murphy, Michael P., Menon, David K., Hutchinson, Peter J., Carpenter, Keri L. H.
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports
Scientific Reports
A key pathophysiological process and therapeutic target in the critical early post-injury period of traumatic brain injury (TBI) is cell mitochondrial dysfunction; characterised by elevation of brain lactate/pyruvate (L/P) ratio in the absence of hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::91efcbd8952272bacc1d9f29826edb12
https://www.repository.cam.ac.uk/handle/1810/286016
https://www.repository.cam.ac.uk/handle/1810/286016
Autor:
Jalloh, Ibrahim, Helmy, Adel, Howe, Duncan J, Shannon, Richard J, Grice, Peter, Mason, Andrew, Gallagher, Clare N, Stovell, Matthew G, Van Der Heide, Susan, Murphy, Michael P, Pickard, John D, Menon, David K, Carpenter, T Adrian, Hutchinson, Peter J, Carpenter, Keri Lh
Following traumatic brain injury, complex cerebral energy perturbations occur. Correlating with unfavourable outcome, high brain extracellular lactate/pyruvate ratio suggests hypoxic metabolism and/or mitochondrial dysfunction. We investigated whethe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca861a93fba38eabcfb5a8db77588c29
https://www.repository.cam.ac.uk/handle/1810/260924
https://www.repository.cam.ac.uk/handle/1810/260924
Autor:
Stovell, Matthew G, Mada, Marius O, Carpenter, T Adrian, Yan, Jiun-Lin, Guilfoyle, Mathew R, Jalloh, Ibrahim, Welsh, Karen E, Helmy, Adel, Howe, Duncan J, Grice, Peter, Mason, Andrew, Giorgi-Coll, Susan, Gallagher, Clare N, Murphy, Michael P, Menon, David K, Hutchinson, Peter J, Carpenter, Keri Lh
Metabolic dysfunction is a key pathophysiological process in the acute phase of traumatic brain injury (TBI). Although changes in brain glucose metabolism and extracellular lactate/pyruvate ratio are well known, it was hitherto unknown whether these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06cd44c1f9c72cbebbed3c94dd5e30c3