Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Steven Jacobson"'
Autor:
Raya Massoud, Irene Cortese, Bridgette Jeanne Billioux, Shila Azodi, Nyater Ngouth, Yoshimi Enose-Akahata, Jennifer E. Dwyer, Steven Jacobson, Satoshi Nozuma, Joan Ohayon, Ashley Vellucci
Publikováno v:
Annals of Clinical and Translational Neurology
Annals of Clinical and Translational Neurology, Vol 8, Iss 10, Pp 1970-1985 (2021)
Annals of Clinical and Translational Neurology, Vol 8, Iss 10, Pp 1970-1985 (2021)
Objective Human T‐cell lymphotropic virus 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic, progressive myelopathy. A high proviral load (PVL) is one of the main risk factors for HAM/TSP. Recently, it was sho
Autor:
Steven Jacobson, Tianxia Wu, Avindra Nath, Pascal Sati, Vincent Van Pesch, Daniel S. Reich, Marie Théaudin, Irene Cortese, Caroline Pot, Massimo Filippi, Vittorio Martinelli, Peter A. Calabresi, Renaud Du Pasquier, M. Absinta, Pietro Maggi, Govind Nair, Roberta Scotti, Gaetano Perrotta, Bryan Smith, Joan Ohayon
Publikováno v:
Ann Neurol
Annals of Neurology, Vol. 88, no. 5, p. 1034-1042 (2020)
Annals of Neurology, Vol. 88, no. 5, p. 1034-1042 (2020)
In multiple sclerosis (MS), a subset of chronic active white matter lesions are identifiable on magnetic resonance imaging by their paramagnetic rims, and increasing evidence supports their association with severity of clinical disease. We studied th
Autor:
Junji Yamauchi, Kenichiro Tanabe, Tomoo Sato, Masanori Nakagawa, Eiji Matsuura, Yoshio Tsuboi, Keiko Tamaki, Hirokuni Sakima, Satoshi Ishihara, Yuki Ohta, Naoki Matsumoto, Kenichi Kono, Naoko Yagishita, Natsumi Araya, Katsunori Takahashi, Yasuo Kunitomo, Misako Nagasaka, Ariella Coler-Reilly, Yasuhiro Hasegawa, Abelardo Araujo, Steven Jacobson, Maria Fernanda Rios Grassi, Bernardo Galvão-Castro, Martin Bland, Graham P. Taylor, Fabiola Martin, Yoshihisa Yamano
Publikováno v:
Viruses, Vol 14, Iss 136, p 136 (2022)
Viruses
Viruses; Volume 14; Issue 1; Pages: 136
Viruses
Viruses; Volume 14; Issue 1; Pages: 136
Corticosteroids are most commonly used to treat HTLV-1-associated myelopathy (HAM); however, their clinical efficacy has not been tested in randomized clinical trials. This randomized controlled trial included 8 and 30 HAM patients with rapidly and s
Autor:
Erin S Beck, David F. Stroncek, Nigar Dargah-Zada, Matthew K. Schindler, Jenifer Dwyer, B Jeanne Billioux, Omar Al-Louzi, Maria Chiara Monaco, John A. Barrett, Lauren B. Reoma, Eugene O. Major, Steven Jacobson, Gina Norato, Frances Andrada, Sandhya R. Panch, Kyle Binder, Irene Cortese, Steven L. Highfill, Bryan Smith, Joan Ohayon, Yoshimi Enose-Akahata, Ikesinachi Osuorah, Avindra Nath, Daniel S. Reich, Pawel Muranski
Publikováno v:
Lancet Neurol
Summary Background Progressive multifocal leukoencephalopathy, a rare disease of the CNS caused by JC virus and occurring in immunosuppressed people, is typically fatal unless adaptive immunity is restored. JC virus is a member of the human polyomavi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b283bf527dd79f4c6194eeaca398ce
https://europepmc.org/articles/PMC8395368/
https://europepmc.org/articles/PMC8395368/
Autor:
Ashley Vellucci, Raya Massoud, Bonita R. Bryant, Joan Ohayon, Irene Cortese, Nyater Ngouth, Unsong Oh, Bridgette Jeanne Billioux, Steven Jacobson, Yoshimi Enose-Akahata, Thomas A. Waldmann
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 8, Pp 1383-1394 (2019)
Annals of Clinical and Translational Neurology
Annals of Clinical and Translational Neurology
Objective Human T cell lymphotropic virus 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic, progressive, neurological disease. Chronic activation of CD8+ T cells, as evidenced by increased spontaneous lymphopro
Autor:
Martina Absinta, Seung Kwon Ha, Nicholas J. Luciano, Steven Jacobson, Pascal Sati, Dragan Maric, Daniel S. Reich, Govind Nair, Nathanael J. Lee, Maria Chiara Monaco
Publikováno v:
Ann Neurol
Accumulating evidence corroborates the role of the "central vein sign" in the radiological diagnosis of multiple sclerosis (MS). Here, we report human magnetic resonance imaging (MRI) and corresponding pathological data that inflammation-dependent in
Autor:
Joan Ohayon, Steven Jacobson, Jun Zhu, Kory R. Johnson, Paolo A. Muraro, Alessandra de Paula Alves Sousa
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
In this study we characterized the TCR repertoire profiles in patients with chronic progressive inflammatory neurological disorders including HAM/TSP, associated with human T-cell lymphotropic virus type I (HTLV-I) infection, and multiple sclerosis (
Haploinsufficiency of immune checkpoint receptor CTLA4 induces a distinct neuroinflammatory disorder
Autor:
Amy Rump, Stefania Pittaluga, V. Koneti Rao, Helen C. Su, Irene Cortese, Gulbu Uzel, Daniel S. Reich, Yoshimi Enose-Akahata, Steven Jacobson, Matthew K. Schindler
Publikováno v:
J Clin Invest
BACKGROUND: Cytotoxic T lymphocyte antigen 4 (CTLA4) is essential for immune homeostasis. Genetic mutations causing haploinsufficiency (CTLA4h) lead to a phenotypically heterogenous, immune-mediated disease that can include neuroinflammation. The neu
Autor:
Mary Alice Allnutt, Juan C. Troncoso, Susan M. Resnick, Philip L. De Jager, Steven Jacobson, Sarah M. Connor, Kory R. Johnson, Olga Pletnikova, Marilyn S. Albert, David A. Bennett, Sonja W. Scholz
Publikováno v:
Neuron
The interplay between viral infection and Alzheimer's disease (AD) has long been an area of interest, but proving causality has been elusive. Several recent studies have renewed the debate concerning the role of herpesviruses, and human herpesvirus 6
Autor:
Nathanael J. Lee, Nicholas J. Luciano, Daniel S. Reich, Martina Absinta, Seung Kwon Ha, Emily C. Leibovitch, Cecil Chern-Chyi Yen, Steven Jacobson, Pascal Sati, Govind Nair, Afonso C. Silva, Tracey A. Rouault
Inflammatory destruction of iron-rich myelin is characteristic of multiple sclerosis (MS). Although iron is needed for oligodendrocytes to produce myelin during development, its deposition has also been linked to neurodegeneration and inflammation, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f93a187ff98b9c7f36a4b9c4806947
https://europepmc.org/articles/PMC6763243/
https://europepmc.org/articles/PMC6763243/