Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Paul J. Nestel"'
Autor:
Terje R. Pedersen, Gregory G. Schwartz, Andrew Tonkin, Anastasia Lesogor, Helen M. Colhoun, Christiane Drechsler, Florian Kronenberg, Peter Willeit, John Simes, Paul M. Ridker, Sotirios Tsimikas, Anders G. Olsson, Samia Mora, Paul J. Nestel, Christoph Wanner
Publikováno v:
Willeit, P, Ridker, P M, Nestel, P J, Simes, J, Tonkin, A M, Pedersen, T R, Schwartz, G G, Olsson, A G, Colhoun, H M, Kronenberg, F, Drechsler, C, Wanner, C, Mora, S, Lesogor, A & Tsimikas, S 2018, ' Baseline and on-statin treatment lipoprotein(a) levels for prediction of cardiovascular events : individual patient-data meta-analysis of statin outcome trials ', The Lancet, vol. 392, no. 10155, pp. 1311-1320 . https://doi.org/10.1016/S0140-6736(18)31652-0
BACKGROUND: Elevated lipoprotein(a) is a genetic risk factor for cardiovascular disease in general population studies. However, its contribution to risk for cardiovascular events in patients with established cardiovascular disease or on statin therap
Autor:
Edward D Janus, S. Mirzaee, David L Hare, Paul J. Nestel, Frank M. van Bockxmeer, Damon A. Bell, Timothy R. Bates, Leon A. Simons, John R. Burnett, Richard C O'Brien, David R. Sullivan, Warrick Bishop, Gerald F. Watts, Andrew Wilson, Karam Kostner, Justin J. Ardill, Jacqueline D.M. Ryan, Jing Pang, Peter M. Clifton, David Colquhoun, Dick C. Chan
Publikováno v:
Heart, lungcirculation. 30(3)
Background Familial hypercholesterolaemia (FH) is under-diagnosed and under-treated worldwide, including Australia. National registries play a key role in identifying patients with FH, understanding gaps in care and advancing the science of FH to imp
Autor:
Dimple Kauhanen, Wolfgang Koenig, Mitja Lääperi, John Simes, Paul J. Nestel, Ottar Nygård, Ben Schöttker, Hermann Brenner, Reijo Laaksonen, Mika Hilvo, David R. Sullivan, Eva Ringdal Pedersen, Natalie A. Mellett, Peter J. Meikle, Antti Jylhä, Dietrich Rothenbacher, Kevin Huynh, Andrew Tonkin, Grethe S. Tell, Indu Dhar, Kaisa M. Koistinen
Publikováno v:
Hilvo, M, Meikle, P J, Pedersen, E R, Tell, G S, Dhar, I, Brenner, H, Schöttker, B, Lääperi, M, Kauhanen, D, Koistinen, K M, Jylhä, A, Huynh, K, Mellett, N A, Tonkin, A M, Sullivan, D R, Simes, J, Nestel, P, Koenig, W, Rothenbacher, D, Nygård, O & Laaksonen, R 2020, ' Development and validation of a ceramide-And phospholipid-based cardiovascular risk estimation score for coronary artery disease patients ', European Heart Journal, vol. 41, no. 3, pp. 371-380 . https://doi.org/10.1093/eurheartj/ehz387
Journal of Heart Failure
Journal of Heart Failure
Aims Distinct ceramide lipids have been shown to predict the risk for cardiovascular disease (CVD) events, especially cardiovascular death. As phospholipids have also been linked with CVD risk, we investigated whether the combination of ceramides wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d82e120fdc0f25a2d9618daf3da8bd
https://cris.vtt.fi/en/publications/e4efcd39-4a58-48ce-a1e9-c8c1058be26d
https://cris.vtt.fi/en/publications/e4efcd39-4a58-48ce-a1e9-c8c1058be26d
Autor:
Anmar A. Khan, Nora E. Straznicky, Gavin W. Lambert, Piyushkumar A. Mundra, Gerard Wong, Theodore W.K. Ng, Zahir H Alshehry, Paul J. Nestel, Ricardo Tan, Christopher K. Barlow, Natalie A. Mellett, Peter J. Meikle, Bronwyn A. Kingwell, Kevin Huynh, Jacquelyn M. Weir
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38:438-447
Objective— High-density lipoprotein (HDL) lipid composition and function may better reflect cardiovascular risk than HDL cholesterol concentration. This study characterized the relationships between HDL composition, metabolism, and function in meta
Autor:
David Colquhoun, Nick Glozier, Brian Oldenburg, Simone Marschner, Adrienne Kirby, Ralph A.H. Stewart, Adrienne O'Neil, Paul J. Nestel, John Simes, Andrew Tonkin, Harvey D. White
Publikováno v:
Heart. 103:1860-1866
A single assessment of psychological distress, which includes depression and anxiety, has been associated with increased mortality in patients with coronary heart disease, but the prognostic importance of persistence of distress symptoms is less cert
Autor:
Nora E. Straznicky, Piyushkumar A. Mundra, Kaushala S. Jayawardana, Gavin W. Lambert, Anmar A. Khan, Paul J. Nestel, Natalie A. Mellett, Peter J. Meikle
Publikováno v:
Atherosclerosis. 256:21-28
Background and aims Plasma sphingolipids including ceramides, and gangliosides are associated with insulin resistance (IR) through effects on insulin signalling and glucose metabolism. Our studies of subjects with metabolic syndrome (MetS) showed clo
Autor:
Zahir H Alshehry, Graham S. Hillis, Kaushala S. Jayawardana, Piyushkumar A. Mundra, Christopher K. Barlow, Sophia Zoungas, Natalie A. Mellett, Paul J. Nestel, Malcolm J. McConville, Elizabeth H Barnes, John Simes, Bronwyn A. Kingwell, Andrew Tonkin, David R. Sullivan, Kevin Huynh, Ian C. Marschner, Peter J. Meikle, Corey Giles, Gerard Wong, Adrienne Kirby, Peter L. Thompson, Mark Woodward, John Chalmers
Publikováno v:
JCI Insight. 4
BACKGROUND: Statins have pleiotropic effects on lipid metabolism. The relationship between these effects and future cardiovascular events is unknown. We characterized the changes in lipids upon pravastatin treatment and defined the relationship with
Autor:
Lesley Cheng, Jennifer F Hoy, Tatiana Pushkarsky, Larisa Dubrovsky, Nigora Mukhamedova, Michael Bukrinsky, Dmitri Sviridov, Andrew F. Hill, Maria Silvana Di Yacovo, Elizabeth M Dewar, Gary L. Simon, Anthony M. Dart, Paul J. Nestel, Maria Saumoy, Catherine Downs, Anh Hoang, Hann Low, Michael L. Fitzgerald
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215620 (2019)
HIV infection is known to be associated with cardiometabolic abnormalities; here we investigated the progression and causes of these abnormalities. Three groups of participants were recruited: HIV-negative subjects and two groups of treatment-naive H
Autor:
Adrienne Kirby, Anthony C Keech, Wendy Hague, Andrew Tonkin, Anne Funke-Kaiser, Paul J. Nestel, Ralph A.H. Stewart, Malcolm J. West, Harvey D. White, David Hunt, Peter L. Thompson, David R. Sullivan, Stefan Blankenberg, R. John Simes, David Colquhoun, Tanja Zeller
Publikováno v:
International Journal of Cardiology. 201:499-507
In patients with stable coronary heart disease (CHD), we aimed to assess 1. the prognostic power of biomarkers reflecting haemodynamics, micronecrosis, inflammation, coagulation, lipids, neurohumoral activity, and renal function; 2. whether changes i
Autor:
Malcolm J. McConville, Gerard Wong, Andrew Tonkin, Bronwyn A. Kingwell, Zahir H Alshehry, Kevin Huynh, Peter L. Thompson, Kaushala S. Jayawardana, Natalie A. Mellett, Piyushkumar A. Mundra, Corey Giles, Sophia Zoungas, Peter J. Meikle, Paul J. Nestel, Elizabeth H Barnes, Graham S. Hillis, John Chalmers, David R. Sullivan, Christopher K. Barlow, Lipid Study Investigators, Mark Woodward, Adrienne Kirby, John Simes
Publikováno v:
JCI insight. 3(17)
BACKGROUND: Plasma lipidomic measures may enable improved prediction of cardiovascular outcomes in secondary prevention. The aim of this study is to determine the association of plasma lipidomic measurements with cardiovascular events and assess thei