Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Michael J. Kelley"'
Autor:
Garth W. Strohbehn, Robert Holleman, Jennifer Burns, Mandi L. Klamerus, Michael J. Kelley, Eve A. Kerr, Nithya Ramnath, Timothy P. Hofer
Publikováno v:
JAMA oncology. 8(11)
ImportanceExtended-interval dosing of pembrolizumab (400 mg every 6 weeks) was approved by US Food and Drug Administration (FDA) in April 2020 as an alternative to standard-interval dosing (200 mg every 3 weeks). Extended-interval dosing may enhance
Autor:
Olivia M. Dong, Salvador Rivas, Michael Naglich, Nina R. Sperber, Catherine Chanfreau-Coffinier, Kara L. Gavin, Megan C. Roberts, Jill S Bates, Jason L. Vassy, R. Ryanne Wu, Deepak Voora, Maria Ribeiro, Michael J. Kelley, Peruvemba Sriram, Corrine I. Voils, C. William Heise, Jennifer G Chapman
Publikováno v:
Pharmacogenomics
Aim: The first Plan-Do-Study-Act cycle for the Veterans Affairs Pharmacogenomic Testing for Veterans pharmacogenomic clinical testing program is described. Materials & methods: Surveys evaluating implementation resources and processes were distribute
Autor:
Julie Lynch, Kristine E. Lynch, Christy Morrissey, Danil V. Makarov, Daniel J. Becker, Michael J. Kelley, Scott E. Sherman, Steve Y. Lee, Kyung Min Lee
Publikováno v:
JCO Precis Oncol
PURPOSEAdvances in precision oncology, including RAS testing to predict response to epidermal growth factor receptor monoclonal antibodies (EGFR mAbs) in colorectal cancer (CRC), can extend patients’ lives. We evaluated uptake and clinical use of K
Autor:
Brian Seal, Candice Yong, Trudy Buckingham, Anna Hung, Kyung Min Lee, Michael J. Kelley, Bradley J. Hintze, Yanhong Li, Shelby D. Reed, Julie Lynch, Olga V. Efimova, Pradeep J. Poonnen
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
BMC Cancer
BMC Cancer
BackgroundThe Veterans Health Administration (VHA) is the largest integrated health care system in the United States (US). Among VHA patients, the rate of use of concurrent chemoradiation therapy (CCRT) among those with unresectable, stage III non-sm
Autor:
Joseph K. Salama, Christina D. Williams, Manisha Palta, Julian C. Hong, Michael J. Kelley, Matthew J. Boyer, Daphna Y. Spiegel
Publikováno v:
Journal of the National Comprehensive Cancer Network. 18:52-58
Background: Adjuvant chemotherapy (AC) after chemoradiation (CRT) and surgery for locoregionally advanced rectal cancer (LARC) is a standard of care in the United States. This study examined the role, optimal regimen, and duration of AC using data fr
Autor:
Harvey G. Moore, Julian C. Hong, Michael J. Kelley, Christina D. Williams, Daphna Y. Spiegel, Manisha Palta, Joseph K. Salama, Matthew J. Boyer
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 103:565-573
Standard therapy for locally advanced rectal cancer includes neoadjuvant chemoradiation and surgery. Complete response (CR) rates after chemoradiation can be as high as 29%, suggesting that nonoperative management (NOM) may be reasonable with appropr
Autor:
Dilhan Weeraratne, Jill E. Duffy, Gretchen Purcell Jackson, Pradeep J. Poonnen, Vishal Vashistha, Jane L. Snowdon, Victoria McCaffrey, Vimla L. Patel, Bradley J. Hintze, Halcyon G. Skinner, Neil L Spector, Michael J. Kelley
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 7, p e0235861 (2020)
PLoS ONE, Vol 15, Iss 7, p e0235861 (2020)
BackgroundTo support the rising need for testing and to standardize tumor DNA sequencing practices within the U.S. Department of Veterans Affairs (VA)'s Veterans Health Administration (VHA), the National Precision Oncology Program (NPOP) was launched
Autor:
Julie Lynch, Michael J. Kelley, Scott L. DuVall, Olga Efimova, Brygida Berse, Vicki L. Venne, Danielle S. Chun, Leland E. Hull, Michael S. Icardi
Publikováno v:
Clinical Breast Cancer. 18:135-143
Introduction Ensuring guideline-concordant cancer care is a Department of Veterans Affairs (VA) priority, especially as the number of breast cancer patients at VA medical centers (VAMCs) grows. We assessed the utilization and clinical impact of the 2
Autor:
David H. Harpole, Christina D. Williams, Joseph K. Salama, Mark W. Onaitis, Michael J. Kelley, Matthew J. Boyer
Publikováno v:
Journal of Thoracic Oncology. 12:1814-1823
Introduction The combined impact of advances in diagnosis and treatment of stage I NSCLC has not been assessed comprehensively. To define the survival impact of modern staging and treatment techniques for clinical stage I NSCLC, the Veterans Administ
Autor:
Michael J. Kelley, Danielle Chun, Scott Kulich, Brygida Berse, Kelly K. Filipski, Benjamin Viernes, Donna R. Rivera, Julie Lynch, Scott L. DuVall
Publikováno v:
Clinical Lung Cancer. 18:401-409
Introduction We examined mutational testing of the epidermal growth factor gene ( EGFR ) and erlotinib treatment among veterans diagnosed with non–small-cell lung cancer in the United States Department of Veterans Affairs (VA). Our objectives were