Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mark Jesky"'
Autor:
Julie Wessels, Markus Storr, Colin A. Hutchison, Mark Jesky, Paul Cockwell, Lesley Fifer, Christopher G. Winearls, Nils Heyne, Veronica Moroz, Julian D. Gillmore, Arthur R. Bradwell, Mark Cook, Katja Weisel
Publikováno v:
The Lancet Haematology. 6:e217-e228
Summary Background In multiple myeloma, severe acute kidney injury due to myeloma cast nephropathy is caused by pathogenic free light chain immunoglobulin in serum. High cutoff haemodialysis (HCO-HD) can remove large quantities of free light chain im
Autor:
Kym I E Snell, J. Pinney, Mark Jesky, Punit Yadav, Paul Cockwell, Stephanie Stringer, Mark Cook, Lesley Fifer, Kolitha Basnayake, Colin A. Hutchison, Mark T. Drayson
Publikováno v:
European Journal of Haematology. 96:610-617
Objectives The aim of this study was to report the long-term outcomes in patients with multiple myeloma (MM) who receive dialysis treatment for acute kidney injury (AKI) due to myeloma cast nephropathy and subsequently recover renal function. Methods
Autor:
Mark Jesky, Paul Cockwell, Anthony Fenton, Punit Yadav, Stephen Harding, Charles J. Ferro, Rachel Webster, Indranil Dasgupta, Iain L. C. Chapple, Stephanie Stringer
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 5, p e0197043 (2018)
PLoS ONE, Vol 13, Iss 5, p e0197043 (2018)
BACKGROUND Patients with chronic kidney disease (CKD) are at an increased risk of developing end-stage renal disease (ESRD). We assessed for the first time whether urinary free light chains (FLC) are independently associated with risk of ESRD in pati
Autor:
Simon C. Satchell, Colin M. Dayan, Paul Cockwell, Alexa Wonnacott, Mark Jesky, Robert H. Jenkins, Thomas P O Ashdown, Timothy Bowen, Donald James Fraser, Christopher P. Carrington, Peter Corish, Lucy J. Newbury, Katherine Simpson, Peter Holmans, Cristina Beltrami
Publikováno v:
Beltrami, C, Simpson, K, Jesky, M, Wonnacott, A, Carrington, C, Holmans, P, Newbury, L, Jenkins, R, Ashdown, T, Dayan, C, Satchell, S, Corish, P, Cockwell, P, Fraser, D & Bowen, T 2018, ' Association of Elevated Urinary miR-126, miR-155, and miR-29b with Diabetic Kidney Disease ', American Journal of Pathology, vol. 188, no. 9, pp. 1982-1992 . https://doi.org/10.1016/j.ajpath.2018.06.006
Effective diabetic kidney disease (DKD) biomarkers remain elusive, and urinary miRNAs represent a potential source of novel noninvasive disease sentinels. We profiled 754 miRNAs in pooled urine samples from DKD patients (n = 20), detecting significan
Autor:
Mark Jesky, Anthony Fenton, Peter Boor, Federica Genovese, Morten A. Karsdal, Daniel Guldager Kring Rasmussen, Martin Tepel, Paul Cockwell, Charles J. Ferro
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Rasmussen, D G K, Fenton, A, Jesky, M, Ferro, C, Boor, P, Tepel, M, Karsdal, M A, Genovese, F & Cockwell, P 2017, ' Urinary endotrophin predicts disease progression in patients with chronic kidney disease ', Scientific Reports, vol. 7, 17328 . https://doi.org/10.1038/s41598-017-17470-3
Scientific Reports
Scientific reports 7, 17328 (2017). doi:10.1038/s41598-017-17470-3
Rasmussen, D G K, Fenton, A, Jesky, M, Ferro, C, Boor, P, Tepel, M, Karsdal, M A, Genovese, F & Cockwell, P 2017, ' Urinary endotrophin predicts disease progression in patients with chronic kidney disease ', Scientific Reports, vol. 7, 17328 . https://doi.org/10.1038/s41598-017-17470-3
Scientific Reports
Scientific reports 7, 17328 (2017). doi:10.1038/s41598-017-17470-3
Scientific reports 7(1), 17328 (2017). doi:10.1038/s41598-017-17470-3
Published by Nature Publishing Group, London
Published by Nature Publishing Group, London
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce16ae8627f30458645a999659e00379
Autor:
Charles J. Ferro, Stephen Harding, Paul Cockwell, Mark Jesky, Katie White, Kolitha Basnayake, Paul Bassett, Hannah Church, Clara E. Green, Colin A. Hutchison, Stephanie Stringer, Anne Burmeister
Publikováno v:
Mayo Clinic Proceedings. 89:615-622
To determine whether elevated serum polyclonal free light chain (FLC) levels predict mortality in a population of individuals with chronic kidney disease (CKD).From January 2, 2006, through July 31, 2007, we recruited a cohort of 848 people with CKD
Autor:
Daniel Guldager Kring Rasmussen, Anthony Fenton, Morten A. Karsdal, Mark Jesky, Paul Cockwell, Signe Holmh Nielsen, Federica Genovese, Susanne Brix, Charles J. Ferro
Publikováno v:
Holm Nielsen, S, Guldager Kring Rasmussen, D, Brix, S, Fenton, A, Jesky, M, Ferro, C J, Karsdal, M, Genovese, F & Cockwell, P 2018, ' A novel biomarker of laminin turnover is associated with disease progression and mortality in chronic kidney disease ', PLOS ONE, vol. 13, no. 10, e0204239 . https://doi.org/10.1371/journal.pone.0204239
Nielsen, S H, Rasmussen, D G K, Brix, S, Fenton, A, Jesky, M, Ferro, C J, Karsdal, M, Genovese, F & Cockwell, P 2018, ' A novel biomarker of laminin turnover is associated with disease progression and mortality in chronic kidney disease ', PLOS ONE, vol. 13, no. 10, e0204239 . https://doi.org/10.1371/journal.pone.0204239
PLoS ONE
PLoS ONE, Vol 13, Iss 10, p e0204239 (2018)
Nielsen, S H, Rasmussen, D G K, Brix, S, Fenton, A, Jesky, M, Ferro, C J, Karsdal, M, Genovese, F & Cockwell, P 2018, ' A novel biomarker of laminin turnover is associated with disease progression and mortality in chronic kidney disease ', PLOS ONE, vol. 13, no. 10, e0204239 . https://doi.org/10.1371/journal.pone.0204239
PLoS ONE
PLoS ONE, Vol 13, Iss 10, p e0204239 (2018)
Background: Patients with chronic kidney disease (CKD) have increased risk of development of endstage renal disease (ESRD) and early mortality. Fibrosis is the central pathogenic process in CKD and is caused by dysregulated extracellular matrix (ECM)
Autor:
Mark Jesky, Bridget Gunson, Vamsidhar B. Dronavalli, Desley Neil, Chandrashekhar A. Kubal, Robert S. Bonser, Paul Cockwell, Rajesh Hanvesakul
Publikováno v:
Transplantation. 93:406-411
Background It is proposed that chronic calcineurin inhibitor (CNI) nephrotoxicity has a central role in chronic kidney disease after nonrenal solid organ transplantation (NRSOT), although there are little data on renal histology in this setting. The
Autor:
Stephen Harding, Mark Jesky, Anthony Fenton, Charles J. Ferro, Indranil Dasgupta, Punit Yadav, Tim Plant, Miguel Ndumbo, Mark T. Drayson, Katerina McCann, Stephanie Stringer, Frank A. Redegeld, Paul Cockwell, Khai Ping Ng
Publikováno v:
European journal of clinical investigation. 46(5)
BACKGROUND Mast cell activation can lead to nonclassical activation of the Renin-Angiotensin-Aldosterone System. However, the relevance of this to human chronic kidney disease is unknown. We assessed the association between serum tryptase, a product
Autor:
Charles J. Ferro, Colin D. Chue, Claire E. Duff, Stephanie Stringer, Mark Jesky, Lorraine Harper, Richard P. Steeds, Jonathan N. Townend, Paul Cockwell, Nicola C. Edwards, Richard Borrows, Matthew J. Simmonds, Sourabh Chand
Publikováno v:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 31(7)
BACKGROUND: Arteriosclerosis is an independent predictor of increased cardiovascular mortality in chronic kidney disease (CKD). Histologically it is characterized by hypertrophy and fibrosis of the arterial media wall leading to increased arterial st