Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Mansi Prakash"'
Publikováno v:
Journal of Neuroscience Research. 98:437-447
In Bioluminescent Optogenetics (BL-OG) a biological, rather than a physical, light source is used to activate light-sensing opsins, such as channelrhodopsins or pumps. This is commonly achieved by utilizing a luminopsin (LMO), a fusion protein of a l
Autor:
Tariq M. Brown, Nicolai Dorka, Mansi Prakash, Jessica R. Zenchak, William E. Medendorp, Lina Marie Wagner, Ute Hochgeschwender, Brandon Palmateer, Eric D. Petersen
Publikováno v:
J Neurosci Res
The need to develop efficient therapies for neurodegenerative diseases is urgent, especially given the increasing percentages of the population living longer, with increasing chances of being afflicted with conditions like Parkinson’s Disease (PD).
Autor:
Mansi Prakash, Jeremy Chou, O Ishaq, David L. Huso, Sonia Franco, I Rybanska, Joshua Bakhsheshian
Poly(ADP-ribose) polymerase 1 (PARP1) interacts genetically with the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) to suppress early-onset T-lineage lymphomas in the mouse, but the underlying mechanisms have remained unknown. To address t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d5162bcd1790e98be21b1a41f2fcf1e
https://europepmc.org/articles/PMC4710090/
https://europepmc.org/articles/PMC4710090/
Autor:
Guosheng Liu, Beatriz Escudero, Mansi Prakash, Benjamin C. Orsburn, Sonia Franco, Silvia Gesheva, David L. Huso
Publikováno v:
Molecular and cellular biology. 30(10)
Combined deficiencies of poly(ADP)ribosyl polymerase 1 (PARP1) and ataxia telangiectasia mutated (ATM) result in synthetic lethality and, in the mouse, early embryonic death. Here, we investigated the genetic requirements for this lethality via analy