Zobrazeno 1 - 10
of 5 563
pro vyhledávání: '"MUSCLE proteins"'
Autor:
Lee-anne S. Chapple, Imre W. K. Kouw, Matthew J. Summers, Luke M. Weinel, Samuel Gluck, Eamon Raith, Peter Slobodian, Stijn Soenen, Adam M. Deane, Luc J. C. van Loon, Marianne J. Chapman
Publikováno v:
American Journal of Respiratory and Critical Care Medicine, 206(6), 740-749. American Thoracic Society
Rationale: Dietary protein may attenuate the muscle atrophy experienced by patients in the ICU, yet protein handling is poorly understood. Objectives: To quantify protein digestion and amino acid absorption and fasting and postprandial myofibrillar p
Autor:
Changhyun Lim, Daniel A. Traylor, Chris McGlory, Sophie Joanisse, James McKendry, Tavneet Grewal, Jonathan C. Mcleod, Todd Prior, Everson A. Nunes, Matthew Lees, Stuart M. Phillips
Publikováno v:
Applied Physiology, Nutrition, and Metabolism. 47:1104-1114
Leucine is a critical amino acid stimulating myofibrillar protein synthesis (MyoPS). The consumption of higher leucine-containing drinks stimulates MyoPS, but we know less about higher leucine solid foods. Here, we examined the effect of short-term r
Autor:
Anayt Ulla, Kanae Osaki, Md Mizanur Rahman, Reiko Nakao, Takayuki Uchida, Isafumi Maru, Kazuaki Mawatari, Tomoya Fukawa, Hiro-Omi Kanayama, Iori Sakakibara, Katsuya Hirasaka, Takeshi Nikawa
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 86:1448-1458
This study investigated the effect of morin, a flavonoid, on dexamethasone-induced muscle atrophy in C57BL/6J female mice. Dexamethasone (10 mg/kg body weight) for 10 days significantly reduced body weight, gastrocnemius and tibialis anterior muscle
Autor:
Lin, Zhang, Wenwu, Li, Yuting, Weng, Keqin, Lin, Kai, Huang, Shaohui, Ma, Jiayou, Chu, Zhaoqing, Yang, Xiaochao, Zhang, Hao, Sun
Publikováno v:
Clinical Genetics. 102:345-349
Limb-Girdle muscular dystrophy (LGMD) is a group of muscle disorders with highly heterogeneous genetic patterns and clinical phenotypes, and this group includes multiple subtypes. Different LGMD subtypes have similar phenotypes and clinical overlaps,
Autor:
Jie Shen, Qingwen Huang, Weiyi Jia, Shengjie Feng, Liang Liu, Xiaolan Li, Deding Tao, Daxing Xie
Publikováno v:
Oncogene. 41:3830-3845
Yes-associated protein 1 (YAP1), a central component of the Hippo pathway, plays an important role in tumor metastasis; however, the underlying mechanism remains to be elucidated. Invadopodia are actin-rich protrusions containing multiple proteases a
Autor:
Paola Barboro, Alessandra Rubagotti, Silvia Poddine, Federica Grillo, Luca Mastracci, Francesco Boccardo
Publikováno v:
The International Journal of Biological Markers. 37:328-335
Purpose Aspartate beta-hydroxylase (ASPH) is a transmembrane protein involved in cancer progression, which has been shown to imply a worse prognosis in several solid tumors. The aim of the present study was to further investigate the prognostic value
Autor:
Ma. A. Reyna-Hernández, Luz del C. Alarcón-Romero, Julio Ortiz-Ortiz, Berenice Illades-Aguiar, Marco A. Jiménez-López, Azucena Ocampo-Bárcenas, Martin O. Morrugares-Ixtepan, Francisco I. Torres-Rojas
Publikováno v:
J Histochem Cytochem
Metabolic reprogramming is typical in cancerous cells and is required for proliferation and cellular survival. In addition, oncoproteins of high-risk human papillomavirus (HR-HPV) are involved in this process. This study evaluated the relationship be
Autor:
Zheng, Wang, Haixia, Li, Hongxia, Wang, Xin, Li, Qiong, Zhang, Haifang, Wang, Kui, Li, Yurong, Qiu
Publikováno v:
Anti-Cancer Drugs. 33:489-501
A hypoxic tumor microenvironment (TME) promotes cancer progression, yet its value as a therapeutic target remains underexploited. Tripartite motif-containing 72 (TRIM72) may protect cells against various stresses including hypoxia. Recently, low TRIM
Autor:
Volker Adams, Antje Schauer, Antje Augstein, Virginia Kirchhoff, Runa Draskowski, Anett Jannasch, Keita Goto, Gemma Lyall, Anita Männel, Peggy Barthel, Norman Mangner, Ephraim B. Winzer, Axel Linke, Siegfried Labeit
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle. 13:1565-1581
About half of heart failure (HF) patients, while having preserved left ventricular function, suffer from diastolic dysfunction (so-called HFpEF). No specific therapeutics are available for HFpEF in contrast to HF where reduced ejection fractions (HFr
Publikováno v:
Am J Physiol Cell Physiol
Duchenne muscular dystrophy (DMD) is an inherited muscle wasting disease. Metabolic impairments and oxidative stress are major secondary mechanisms that severely worsen muscle function in DMD. Here, we sought to determine whether germline reduction o